TY - JOUR A1 - Heiser, A. A1 - Müller-Ruchholtz, W. A1 - Ulrichs, Karin T1 - Isolation of Islets of Langerhans: Improvement of the Isolation Technique Using the Pig Model. N2 - During the last view years, interest in pancreatic islet transplantation for the cure of type I diabetes has increased markedly. A serious barrier to clinical islet transplantation is the isolation of a sufficient mass of viable and functional islets. We used a porcine islet isolation model to examine various parameters of the isolation procedure and to improve isolation technique. KW - Langerhans-Inseln Y1 - 1994 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-87765 ER - TY - JOUR A1 - Dickneite, G. A1 - Schorlemmer, H. U. A1 - Sedlacek, H. H. A1 - Falk, W. A1 - Ulrichs, Karin A1 - Müller-Ruchholtz, W. T1 - Suppression of macrophage function and prolongation of graft survival by the new guanidinic-like structure, 15-deoxyspergualin N2 - No abstract available. KW - Makrophage Y1 - 1987 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-86991 ER - TY - JOUR A1 - Winoto-Morbach, S. A1 - Leyhausen, G. A1 - Müller-Ruchholtz, W. A1 - Ulrichs, Karin T1 - The Electromagnetic Separation Principle: A Basis for Human Pancreatic Islet Transplantation N2 - No abstract available KW - Allergie Y1 - 1988 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-82520 ER - TY - JOUR A1 - Ulrichs, Karin A1 - Keller, R. A1 - Müller-Ruchholtz, W. T1 - Serological demonstration and manipulation of passenger cells (PC) in pancreas islet grafts N2 - No abstract available KW - Immunobiologie Y1 - 1985 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-72944 ER - TY - JOUR A1 - Laus, R. A1 - Ulrichs, Karin A1 - Müller-Ruchholtz, W. T1 - Molecular Specificity of Human Heterophile Antibodies (HHA) in Normal Human Serum (NHS) Reacting with Xenogeneic Cells. N2 - No abstract available KW - Immunobiologie Y1 - 1986 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-72921 ER - TY - JOUR A1 - Ulrichs, Karin A1 - Winoto-Morbach, S. A1 - Hering, B. A1 - Müller-Ruchholtz, W. T1 - A Useful Biotechnological Approach to Solve the Problem of Graft Purity in Human Pancreatic Islet Transplantation N2 - No abstract available KW - Chirurgie Y1 - 1990 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-45619 ER - TY - JOUR A1 - Ulrichs, Karin A1 - Müller-Ruchholtz, W. T1 - Further Analyses of Pancreas Islet Immunogenicity, a Major Barrier to Successful Islet Transplantation N2 - No abstract available KW - Chirurgie Y1 - 1985 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-45563 ER - TY - JOUR A1 - Ulrichs, Karin A1 - Müller-Ruchholtz, W. T1 - Expression of MHC Structures on Immunologically Reactive and Non Reactive Cells in Islets of Langerhans and Other Tissues N2 - No abstract available KW - Chirurgie Y1 - 1988 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-45557 ER - TY - JOUR A1 - Ulrichs, Karin A1 - Bosse, M. A1 - Wacker, HH A1 - Heiser, A. A1 - Müller-Ruchholtz, W. T1 - Histologic analysis of the porcine pancreas to improve islet yield and integrity after collagenase digestion N2 - No abstract available KW - Chirurgie Y1 - 1994 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-45166 ER - TY - JOUR A1 - Heiser, A. A1 - Ulrichs, Karin A1 - Müller-Ruchholtz, W. T1 - Influence of porcine strain, age, and pH of the isolation medium on porcine pancreatic islet isolation success N2 - No abstract available KW - Chirurgie Y1 - 1994 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-45171 ER - TY - JOUR A1 - Winoto-Morbach, S. A1 - Krout, OS A1 - Heiser, A. A1 - Ulrichs, Karin A1 - Müller-Ruchholtz, W. T1 - Lectin binding to acinar tissue for complete magnetophoretic purification of porcine pancreatic islets depends on the composition and pH of the incubation medium N2 - No abstract available KW - Chirurgie Y1 - 1994 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-45183 ER - TY - JOUR A1 - Ulrichs, Karin A1 - Müller-Ruchholtz, W. T1 - Significant manipulative procedures to reduce immunogenicity of human islet allografts N2 - No abstract available KW - Chirurgie Y1 - 1989 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-45155 ER - TY - JOUR A1 - Ulrichs, Karin A1 - Kaitschick, J. A1 - Bartlett, R. A1 - Müller-Ruchholtz, W. T1 - Suppression of natural xenophile antibodies with the novel immunomodulating drug leflunomide N2 - No abstract available KW - Chirurgie Y1 - 1992 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-45202 ER - TY - JOUR A1 - Falk, W. A1 - Ulrichs, Karin A1 - Müller-Ruchholtz, W. T1 - 15-Deoxyspergualin (a new guanidine-like drug) blocks T lymphocyte proliferation N2 - No abstract available KW - Chirurgie Y1 - 1987 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-45215 ER - TY - JOUR A1 - Kekow, J. A1 - Ulrichs, Karin A1 - Müller-Ruchholtz, W. A1 - Gross, WL T1 - Pancreas transplantation: a study of insulin secretion in isolated islets of Langerhans and in sera using a new enzyme-linked immunosorbent assay N2 - No abstract available KW - Chirurgie Y1 - 1987 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-45229 ER - TY - JOUR A1 - Eckstein, V. A1 - Ulrichs, K. A1 - Meincke, G. A1 - Müller-Ruchholtz, W. T1 - Natural xenophile antibodies from sera of type I diabetic patients differ strongly in their reactivity against various porcine pancreatic cells N2 - No abstract available KW - Chirurgie Y1 - 1992 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-45277 ER - TY - JOUR A1 - Deltz, E. A1 - Müller-Hermelink, HK A1 - Ulrichs, Karin A1 - Thiede, A. A1 - Müller-Ruchholtz, W. T1 - Development of graft-versus-host reaction in various target organs after small intestine transplantation N2 - The GVHRIL foHowing transplantation of small intestine are different from those found after bone marrow transplantation or spleen cell injections in that they show a remarka ble, significant prevalence of lesions within the intestinal mucosa. These findings are consistent with the observation that jntestinal lymphocytes newly formed in mesenteric lymph nodes predominantly home in on the intestine again.& The degree of histologic alteration within different tissues indicates that the graft and the host may survive the lesions of the lymphatic tissues, whereas the severe intestinal lesions following GVHR may easily cause death of the recipient. With regard to clinical sman bowel transplantation two statements can be made: (l) GVHRIL play a significant role in small bowel trans~ plantation. (2) To minimize their biologic importance, a selective elimination of the graft's Jymph nodes by irradiation or surgical resection should be considered in view of the remarkable difference between GVHRIL in lymph nodes and in the graft's intestinal wall itself. KW - Chirurgie Y1 - 1981 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-45459 ER - TY - JOUR A1 - Winoto-Morbach, S. A1 - Ulrichs, Karin A1 - Hering, BJ A1 - Leyhausen, G. A1 - Müller-Ruchholtz, W. T1 - Lectins for electromagnetic purification of islets from humans and large mammals N2 - No abstract available KW - Chirurgie Y1 - 1990 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-45430 ER - TY - JOUR A1 - Ulrichs, Karin A1 - Müller-Ruchholtz, W. T1 - Mixed lymphocyte islet culture (MLIC) and its use in manipulation of human islet alloimmunogenicity N2 - No abstract available Y1 - 1990 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-45515 ER - TY - JOUR A1 - Ulrichs, Karin A1 - Kuhlencordt, KM A1 - Müller-Ruchholtz, W. T1 - Plating inhibition assay (PIA): a new test for cell mediated cytotoxicity N2 - No abstract available Y1 - 1979 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-45443 ER -