TY - JOUR A1 - Tacke, Reinhold A1 - Wannagat, U. T1 - N-Quaternäre Derivate basischer Sila-benzhydryläther T1 - N-Quaternary Derivatives of Basic Silabenzhydryl Ethers N2 - Die quartären Ammoniumsalze 1-10 einiger bioaktiver Sila-benzhydryläther wurden erstmalig durch Reaktion der entsprechenden freien Basen A-E mit CH\(_3\)J, CH\(_3\)Br bzw. CH\(_3\)Cl in CH\(_3\)CN dargestellt. Die Strukturen von 1-10 wurden durch Elementaranalysen und 1 H-NMR-Spektren bestätigt. Die pharmakologischen Effekte einiger Verbindungen wurden sowohl mit den Eigenschaft der entsprechenden freien Basen als auch mit einigen Struktur-Wirkungsbeziehungen analoger Kohlenstoffverbindungen verglichen. N2 - Quaternary ammonium salts 1-10 of some biologically active silabenzhydryl ethers were synthesized for the frrst time by the reaction of the corresponding free bases A-E with CH\(_3\)I, CH\(_3\)Br or CH\(_3\)Cl in CH\(_3\)CN. The structures of 1-10 were confirmed by elementary analysis and 1 HNMR spectroscopy. The pharmacological effects of some compounds were compared with those of the corresponding free bases and of analogaus carbon cornpounds. KW - Anorganische Chemie Y1 - 1977 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-63583 ER - TY - JOUR A1 - Tacke, Reinhold T1 - Sila-Analoga des Meflophenhydramins T1 - Sila-analogues of Meflophenhydramine N2 - Die Sila-Analoga A, 8, C des Antihistaminikums Meflophenhydramin, sowie die Derivate D und E, das Hydrolyseprodukt 8 und die Vorstufen 3-7 wurden dargestellt. Die chemischen und physikalischen Eigenschaften aller Verbindungen und das pharmakologische Verhalten von A-D und 8 wurden untersucht. N2 - Sila-analogues A, 8, C of the antihistamine meflophenhydramine as weil as the derivatives D and E, the product of hydrolysis 8 and the precursors 3-7 were synthesized. The chemical and physical properties and the pharmacological behaviour of A-D and 8 are described. KW - Anorganische Chemie Y1 - 1977 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-63594 ER - TY - JOUR A1 - Burschka, Christian A1 - Bronger, W. T1 - Über die Struktur von CsAg\(_3\)S\(_2\) und RbAg\(_3\)S\(_2\) T1 - The Crystal Structure of cesium silver sulfide (CsAg\(_3\)S\(_2\)) and rubidium silver sulfide (RbAg\(_3\)S\(_2\)) N2 - Die Synthese von CsAg\(_3\)S\(_2\) und RbAg\(_3\)S\(_2\) gelingt durch Umsetzungen von Alkalimetallcarbonaten mit Silber und Schwefel in der Schmelze. Röntgenbeugungsuntersuchungen an Einkristallen ergaben, daß die Schichtstruktur dieser beiden isotypen Verbindungen mit der von K\(_2\)Ag\(_4\)Sa [1] verwandt ist. In allen drei Thioargentaten fanden wir die gleichen röhrenförmigen SilberSchwefel- Verbände. Durch eine verschiedene Verknüpfung dieser Verbände wird der unterschiedlichen Stöchiometrie der Verbindungen Rechnung getragen. N2 - Fusion reactions of alkali carbonates with silver and sulfur led to the compounds CsAg\(_3\)S\(_2\) and RbAg\(_3\)S\(_2\) X.my investigations on single crystals revealed that their structure is closely related to that of ~A~Sa (1]. A channel-Iike arrangement in the silver·sulfur network was found in both of the structures. According to the difference in stoichiometry. the compounds show a different type of linkage between these silver·sulfur channels. KW - Chemie Y1 - 1977 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-31393 ER - TY - JOUR A1 - Tacke, Reinhold A1 - Saad, S. M. T1 - Silylation of cellulose N2 - Ethane-l:2-diol and propane-l:3-diol reaet with 1: 1:3:3-tetramethyl-l:3-dichlorodisiloxane forming the corresponding rings. However, no ring compounds could be traced tbrough the reaction between butane-l :4-diol, glycerol and the dichlorodisiloxane respectively, where only polymeric compounds are formed. The silylation products of the di- and trihydroxy alcohols, as model compounds, has confirmed that the ring formation during silylation of cellulose with dichlorodisiloxane is uncertain. KW - Anorganische Chemie Y1 - 1977 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-78368 ER - TY - JOUR A1 - Saad, S. M. A1 - Tacke, Reinhold T1 - Zur Darstellung von 1,1,3,3-Tetramethyl-1,3-disila-2,4,7-trioxa-cycloheptan (1) und 1,1,3,3-Tetramethyl-1,3-disila-2,4,8-trioxa-cyclooctan (2) N2 - No abstract available. KW - Anorganische Analyse Y1 - 1977 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-86958 ER - TY - JOUR A1 - Werner, H. A1 - Leonhard, K. A1 - Burschka, Christian T1 - Basische Metalle: IX. Synthese und Kristallstruktur von C\(_5\)H\(_5\)Co(PMe\(_3\))CS\(_2\) : Reaktionen zu zweikernkomplexen mit Co(SCS)Cr- und Co(SCS)Mn-Brückenbindungen T1 - Basic metals. IX. Synthesis and crystal structure of C\(_5\)H\(_5\)Co(PMe\(_3\))CS\(_2\). Reactions to binuclear complexes with Co(SCS)Cr and Co(SCS)Mn bridging compounds. N2 - Durch Reaktion von C\(_5\)H\(_5\)Co(PMe\(_3\))\(_2\) (I) oder des Hetero-Zweikernkomplexes C\(_5\)H\(_5\)(PMe\(_3\))Co(CO)\(_2\)Mn(CO)C\(_3\)H .. Me (III) mit CS\(_2\) entsteht in praktisch quantitativer Ausbeute C\(_5\)H\(_5\)Co(PMe\(_3\))CS\(_2\) (IV). Die Kristallstruktur zeigt, dass der Carbondisulfid-Ligal'ld iiber Kohlenstoff und ein Schwefelatom (S(2)) dihaptogebunden vorliegt (Co-C = 1.89, Co-S(2) = 2.24 A, S(2)-C-S(1) = 141.2°). Die beiden C-S-AbsUinde in IV (C-S(2) = 1.68, C-S(l) = 1.60 A) sind gegenliber dem C-S-Abstand in freiem CS\(_2\) (1.554 A) aufgeweitet, was in Einklang mit dem aus spektroskopischen Daten zu folgernden starken 1T-Akzeptorcharakter von h\(^2\)-CS\(_2\) steht. IV reagiert mit Cr(CO)\(_5\)THF und C\(_5\)H\(_5\)Mn(CO)\(_2\)THF zu den Komplexen C\(_5\)H\(_5\)(PMe\(_3\))Co(SCS)Cr(CO)\(_5\) (V) bzw. C\(_5\)H\(_5\)(PMe\(_3\))Co(SCS)Mn(CO)\(_2\)C\(_5\)H\(_5\) (VI), in den en das in IV nicht am Cobalt gebundene Schwefelatom S(l) als Koordinationspartner gegenüber den 16-Elektronen-Fragmenten Cr(CO)\(_5\) und Mn(CO)\(_2\)C\(_5\)H\(_5\) fungierl. Die spektroskopischen Daten von IV, V und VI werden diskutiert. N2 - C\(_5\)H\(_5\)Co(PMe\(_3\))CS\(_2\) (IV) is formed in practically quantitative yield in the reaction of C\(_5\)H\(_5\)Co(PMe\(_3\))\(_2\) (I) or the heterobinuclear complex C\(_5\)H\(_5\)(PMe\(_3\))Co(CO)\(_2\)Mn(CO)C\(_3\)H .. Me (III) with CS\(_2\). The crystal structure shows that the carbon disulfide bonds as a dihapto ligand through the carbon and one sulfur atom (S(2)) (Co-C = 1.89, Co-S(2) = 2.24 ft., S(2)-C-S(1) = 141.2°). The two C-S bond lengths in IV (C-S(2) = 1.68, C-S(l) = 1.60 A) are greater than in free CS\(_2\) (1.554 A) which is in agreement with the strong 7T-acceptor character of h\(^2\)-CS\(_2\) as shown in the spectroscopic data. IV reacts with Cr(CO)\(_5\)THF and C\(_5\)H\(_5\)Mn(CO)\(_2\)THF to give the complexes C\(_5\)H\(_5\)(PMe\(_3\))Co(SCS)Cr(CO)\(_5\) (V) and C\(_5\)H\(_5\)(PMe\(_3\))Co(SCS)Mn(CO)\(_2\)C\(_5\)H\(_5\) (VI) respectively, in which the sulfur atom S(l) that is not bound to cobalt coordinates to the 16-electron fragments Cr(CO)\(_5\) and Mn(CO)\(_2\)C\(_5\)H\(_5\). The spectroscopic data of IV, V and VI are discussed. KW - Anorganische Chemie Y1 - 1978 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-70444 ER - TY - JOUR A1 - Wieber, Markus A1 - Burschka, Christian A1 - Baudis, Ulrich T1 - Darstellung und Molekülstruktur von 2-Methylthio-1,3,2-benzodithiastibol T1 - Preparation and X-ray structure of 2-Methylthio-l,3,2-benzodithiastibole N2 - No abstract available KW - Chemie Y1 - 1978 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-46772 ER - TY - JOUR A1 - Tacke, Reinhold A1 - Niederer, Reinhold T1 - Sila-Pharmaka, 9. Mitt. [1] Darstellung und Eigenschaften potentiell curarewirksamer Silicium-Verbindungen, I T1 - Sila-Drugs, 9th Communication [1] Preparation and Properties of Silicon Compounds with Potential Curare-Like Activity, I JF - Zeitschrift für Naturforschung B N2 - Organosilicon compounds 8, 9 and 10 with potential curare-like action and their precursors 0, 6 and 7 were synthesized for the first time. 0-10 were characterized by their physical and chemical properties, and their structures were confirmed by analyses, IH NMR and mass spectroscopy (only for 0-7). The pharmacological and toxicological data of 8, 9 and 10 are reported. KW - curare-like activity KW - toxicological properties KW - pharmacological properties KW - silicon compounds Y1 - 1978 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-128277 VL - 33 IS - 4 ER - TY - JOUR A1 - Burschka, Christian T1 - Intermolekulare Koordination bei zyklischen Esternder stibonigen und der thiostibonigen Säure T1 - Intermolecular Coordination in Cyclic Esters of Stibonic Acid and Thiostibonic Acid N2 - Die Struktur von EinkristalIen des 2-Methoxi-l,3, 2-benzodioxastibols und des 2-Methylthio-l, 3, 2-benzodithiastibols konnte über Röntgendiffraktometermessungen ermittelt werden. Die Verbindungen kristallisieren beide monoklin mit Elementarzellen, die jeweils 4 Formeleinheiten enthalten, sie sind jedoch nicht isomorph. Als Raumgruppe ergibt sich P21/n bzw. P21/c. Ungewöhnlich kurze intermolekulare Antimon-Chalkogen-Abstände lassen in der Struktur des Oxastibols koordinative Bindungen erkennen, die in dieser Stärke beim Thiastibol nicht auftreten. N2 - The crystal structure of 2-methoxi-l,3,2-benzodioxastibole and of 2-methylthio- 1,3,2-benzodithiastibole was solved by X-ray diffraction methods. The compounds crystallize with monoclinic unit cells which contain 4 formula units each, they are, however, not isomorphou8. The space grol1p is P21/n and P21/c, respectively. Unusually short intermolecular antimony.-chalcogen distances revenl the existance of additional coordinative bonds within the structure of the oX3stiboJe which to such an extent cannot be observed within the corresponding thiastibole. KW - Chemie Y1 - 1978 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-31374 ER - TY - JOUR A1 - Burschka, Christian T1 - Na\(_3\)Cu\(_4\)S\(_4\) - ein Thiocuprat mit verknüpften \(^1 _\infty\)[Cu\(_4\)S\(_4\)]-Ketten N2 - No abstract available KW - Chemie Y1 - 1979 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-46828 ER - TY - JOUR A1 - Burschka, Christian T1 - Zur Kristallstruktur der Thiocuprate K\(_3\)Cu\(_8\)S\(_6\) und Rb\(_3\)Cu\(_8\)S\(_6\) N2 - No abstract available KW - Chemie Y1 - 1979 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-46819 ER - TY - JOUR A1 - Schmidt, M. A1 - Bender, R. A1 - Burschka, Christian T1 - Additionsverbindungen zwischen Antimon(III)-Halogeniden und 1,4-Dithiacycloheptan T1 - Addition Compounds between Antimony(III)-Halides and 1,4-Dithiacycloheptane N2 - No abstract available KW - Chemie Y1 - 1979 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-46570 ER - TY - JOUR A1 - Burschka, Christian A1 - Wieber, Markus T1 - Eine pentagonal pyramidale Koordination des Bismuts. Kristallstruktur von Methylbismutbis(dietyldithiocarbonat) T1 - A pentagonal pyramidal coordination of Bismut. Crystal structure of Methylbismuthbis(diethyldithiocar bamate) N2 - The crystal structure of the title compound, recrystallized from ethanol, was solved by means of X-ray diffraction methods and could be refined to an R-value of 0.050 with 2126 reflections observed. In contrast to its behaviour in benzene solution, where the compound is monomerie, in the crystalline state dimerie units are formed by intermoleeular Bi-S-interactions. The bismuth atoms are coordinated in form of a slightly distorted pentagonal pyramid with the free electron pair presumably directed opposite the apical C-atom. KW - Chemie Y1 - 1979 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-46750 ER - TY - JOUR A1 - Steiling, L. A1 - Tacke, Reinhold A1 - Wannagat, U. T1 - Diphenyl(3-piperidinopropyl)silanol, ein Sila-Analogon des Difenidols T1 - Dipbenyl(3-piperidinopropyl)silanol, a Sila-Analogue of Difenidol N2 - Diphenyl(3-piperidinopropyl)silanol (6b), ein Sila-Analogon des Arzneimittels Difenidol (6a), und dessen Methoiodid 7 wurden erstmals gemäß Schema 1 synthetisiert. - Die pharmakologischen und toxikologischen Eigenschaften der Analoga 6a und 6b wurden vergleichend untersucht. N2 - Diphenyl(3-piperidinopropyl)silanol (6b), a sila-analogue of the drug difenidol (6a), and its methoiodide 7 were synthesized for the firsttime according to scheme 1. - The pharmacological and toxicological properties of the analogues 6a and 6b were investigated comparatively. KW - Anorganische Chemie Y1 - 1979 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-63618 ER - TY - JOUR A1 - Ackermann, J. A1 - Tacke, Reinhold A1 - Wannagat, U. A1 - Koke, U. A1 - Meyer, F. T1 - Derivate des 1-(4-Chlorphenyl)silacyclohexans mit 3-(Diethylamino)propyl- und 2-(Diethylamino)ethyl-Gruppierungen T1 - Derivatives of 1-(4-Chlorophenyl)silacyclobexane with 3-(Diethylamino)propyl- and 2-(Diethylamino)etbyl Groups N2 - Die Darstellung der Verbindungen 3a (sowie 3b) und 10, die sich vom 1-(4-Chlorphenyl)-1-(2~ diethylaminoethoxy)silacyclohexan (Sila-Chlorphencyclan, II a) ableiten, wird beschrieben. Die Verbindung 3 b wurde pharmakologisch und toxikologisch untersucht. Die biologischen Eigen· schaften von 3b wurden mit denen von Ila (sowie Chlorphencyclan) und seinem Hydrochiarid Ilb verglichen. N2 - The preparation of the compounds 3a (and 3b) and 10, which derive from 1-(4-chlorophenyl)-1· (2-diethylaminoethoxy)silacyclohexane (sila-chlorophencyclane, II a). is described. Compound 3 b has been investigated pharmacologically and toxicologically. The biological properties of 3 b and those of ßa (and chlorophencyclane) and its hydrochloride Ilb are compared. KW - Anorganische Chemie Y1 - 1979 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-63621 ER - TY - JOUR A1 - Tacke, Reinhold A1 - Zimonyi-Hegedüs, E. A1 - Wannagat, U. T1 - Si-C-Spaltung in 2-Thienylsilanen durch sekundäre Amine N2 - Die Umsetzung von Diphenyl-vinylsilan mit zyklischen sekundären Aminen (z.B. Morpholin) in Gegenwart der entsprechenden Lithium-amide führt zu einer Substitution des an Silicium gebundenen H-Atoms durch eine Aminogruppe und zu einer Addition des Amins an die Vinylgruppe. 2-Thienylphenyl- vinylsilan reagiert jedoch zusätzlich unter Spaltung der Si-e-Bindung und Aminosubstitution der 2-Thienylgruppe. N2 - Treatment of diphenylvinylsilane with cyclic secondary amines (e.g. morpholine) in the presence of the corresponding Iithium amides leads to substitution of the SiH hydrogen atom by an amino group and to. addition of the amine to the vinyl group. A similar reaction observed in the case of 2-thienylphenylvinylsilane is accompanied by cleavage of the Si-e band and substitution of the 2-thienyl group by an amino group. KW - Anorganische Chemie Y1 - 1979 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-63608 ER - TY - JOUR A1 - Tacke, R. A1 - Strecker, M. A1 - Sheldrick, W. S. A1 - Heeg, E. A1 - Berndt, B. A1 - Knapstein, K. M. T1 - Sila-Pharmaka, 14. Mitt. Darstellung und Eigenschaften sowie Kristall-und Molekülstruktur von Sila-Difenidol JF - Zeitschrift für Naturforschung B N2 - Sila-difenidol (6b), a sila-analogue of the drug difenidol (6a), was synthesized according to Scheme 1. 6b and its new precursors 3 and 5 were characterized by their physical and chemical properties, and their structures confirmed by elementary analyses, 1H NMR and mass spectroscopy. 6 b crystallizes orthorhombic \(P2_12_12_1\) with a = 11.523(1), b = 14.366(4), c = 11.450(1) Å, Z = 4, \(D_{ber} = 1.14 gcm^{-3}\). The structure was refined to R = 0.050 for 1897 reflexions. A strong nearly linear intramolecular O-H···N hydrogen bond of 2.685 Å is observed. The anticholinergic, histaminolytic and musculotropic spasmolytic activities of 6 a and 6 b are reported. KW - sila-difenidol KW - syntheses KW - crystal structure KW - molecular structure KW - biological activity Y1 - 1979 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-128391 VL - 34 IS - 9 ER - TY - JOUR A1 - Tacke, Reinhold A1 - Haller, Ingo A1 - Zeiler, Hans-Joachim T1 - Sila-Analoga der Antiseptica Octafoniumchlorid und p-tert-Butylphenol N2 - No abstract available. KW - Silaanaloga KW - Antiseptikum Y1 - 1979 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-86893 ER - TY - JOUR A1 - Werner, Helmut A1 - Kuehn, Alfred A1 - Burschka, Christian T1 - Strukturdynamische Organometall-Komplexe II: Synthese, Struktur und Dynamik der Komplexe C\(_5\)H\(_5\)M(2-R'C\(_3\)H\(_4\))PR\(_3\) (M = Pd, Pt) T1 - Structurally dynamic organometallic complexes II: Synthesis, structure, and dynamics of the complexes C\(_5\)H\(_5\)M(2-R'C\(_3\)H\(_4\))PR\(_3\) (M = Pd, Pt) N2 - No abstract available KW - Anorganische Chemie Y1 - 1980 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-57853 ER - TY - JOUR A1 - Burschka, Christian T1 - Kristallstruktur von NH\(_4\)CuS\(_4\) T1 - The crystal structure of NH\(_4\)CuS\(_4\) N2 - NH4CuS4 was prepared according to syntheses reported in the literature. Orthorhombic crystals could be grown (P21 21 21 , a = 5.249(1), b = 8.444(2), c = 12.782(2) A, Z = 4), the structure of which was solved from X-ray diffractometer data. (R = 0.031 for 767 obs. reflections). In the solid state (CuS4)- chelate rings are linked via additional Cu-S-bonds to form one-dimensional polymerie anions. KW - Chemie KW - Crystal Structure KW - Copper Polysulfides KW - Chain Polymers Y1 - 1980 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-46763 ER -