TY - CHAP A1 - Schmitz, Barbara T1 - War, violence and Tyrannicide in the Book of Judith N2 - No abstract available KW - Judit KW - Gewalt KW - Krieg KW - Tyrannenmord KW - Judith KW - Violence KW - War KW - Tyrannicide Y1 - 2010 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-67058 ER - TY - CHAP A1 - Schmitz, Barbara T1 - Geschaffen aus dem Nichts? Die Funktion der Rede von der Schöpfung im Zweiten Makkabäerbuch N2 - No abstract available KW - Makkabäer KW - Schöpfung KW - Maccabean books KW - Creation Y1 - 2010 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-67038 ER - TY - CHAP A1 - Schmitz, Barbara T1 - "Dir soll Deine ganze Schöpfung dienen" (Jdt 16,14). Schöpfungstheologie im Buch Judit N2 - No abstract available KW - Judit KW - Schöpfungslehre KW - Schöpfung KW - Judith KW - Creation Y1 - 2010 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-67042 ER - TY - CHAP A1 - Schlosser, Daniel A1 - Jarschel, Michael A1 - Duelli, Michael A1 - Hoßfeld, Tobias A1 - Hoffmann, Klaus A1 - Hoffmann, Marco A1 - Morper, Hans Jochen A1 - Jurca, Dan A1 - Khan, Ashiq T1 - A Use Case Driven Approach to Network Virtualization N2 - In today's Internet, services are very different in their requirements on the underlying transport network. In the future, this diversity will increase and it will be more difficult to accommodate all services in a single network. A possible approach to cope with this diversity within future networks is the introduction of support for running isolated networks for different services on top of a single shared physical substrate. This would also enable easy network management and ensure an economically sound operation. End-customers will readily adopt this approach as it enables new and innovative services without being expensive. In order to arrive at a concept that enables this kind of network, it needs to be designed around and constantly checked against realistic use cases. In this contribution, we present three use cases for future networks. We describe functional blocks of a virtual network architecture, which are necessary to support these use cases within the network. Furthermore, we discuss the interfaces needed between the functional blocks and consider standardization issues that arise in order to achieve a global consistent control and management structure of virtual networks. KW - Virtualisierung KW - Datenkommunikationsnetz KW - Internet KW - Rechnernetz KW - Anwendungsfall KW - Netzvirtualisierung KW - Standardisierung KW - Use case KW - network virtualization KW - future Internet architecture KW - standardization Y1 - 2010 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-55611 N1 - Accepted at IEEE Kaleidoscope 2010 ER - TY - CHAP A1 - Scheuermann, Manuela T1 - Effective or multilateral? The UN-EU partnership in military crisis management N2 - For the EU “effective multilateralism” in, with and within international organisations is the foundation of a system of global governance, so is laid down in the ESS. Therefore the term is used to label the EU’s activities in the UN-family and to characterise the relations with the UN in the wider context of global governance. It is the political argument for the EU’s commitment in military crisis management, side by side with UN peacekeepers. The UN in turn speaks of multilateralism to call for the EU’s loyalty and partnership. Both organisations build their partnership on the common normative ground of multilateralism. The paper questions these rhetorical denominations critically. It goes beyond the political declarations to analyse the degree and quality of “effective multilateralism” in reality in and with international organisations, using the example of UN-EU-relations in military crisis management. The theoretical approach of multilateralism serves as the starting point of the analysis and theoretical basis of the paper (Chapter 1). The special EU-touch in “effective multilateralism” in comparison to the “UN-touch” is subject of Chapter 2. This analysis is necessary due to the meanwhile inflationary use of the term “effective multilateralism” in almost every CSFP context. Are the institutional steps to a partnership in crisis management as well as the operational collaboration in DR Congo (2003/2006/2009) and Chad/CAR (2008/2009) in line with “multilateralism”? is the question that is answered in the paper (Chapter 3). KW - Friedenssicherung KW - Europäische Sicherheits- und Verteidigungspolitik KW - Multilateralismus KW - Krisenmanagement KW - inter-organisationale Beziehungen KW - GSVP KW - UN-Friedenssicherung KW - inter-organisational relations KW - CSDP KW - UN-peacekeeping KW - multilateralism KW - crisis management Y1 - 2011 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-65565 ER - TY - CHAP A1 - Scheer, Ulrich A1 - Trendelenburg, M. F. A1 - Franke, Werner W. T1 - Regulation of transcription of ribosomal RNA genes during amphibian oogenesis N2 - No abstract available Y1 - 1976 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-33700 ER - TY - CHAP A1 - Scheer, Ulrich A1 - Rose, Kathleen M. T1 - Localization of RNA polymerase I in interphase cells and mitotic chromosomes by light and electron microscopic immunocytochemistry N2 - Rabbit antibodies to RNA polymerase I from a rat hepatoma have been used to localize the enzyme in a variety of cells at the light and electron microscopic level. In interphase cells the immunofluorescence pattern indicated that polymerase I is contained exclusively within the nucleolus. That this fluorescence, which appeared punctated rather than uniform, represented transcriptional complexes of RNA polymerase I and rRNA genes was suggested by the observation that it was enhanced in regenerating liver and in a hepatoma and was markedly diminished in cells treated with actinomycin D. Electron microscopic immunolocalization using gold-coupled second antibodies showed that transcribed rRNA genes are located in, and probably confined to, the fibrillar centers of the nucleolus. In contrast, the surrounding dense fibrillar component, previously thought to be the site of nascent prerRNA, did not contain detectable amounts of polymerase I. During mitosis, polymerase I molecules were detected by immunofluorescence microscopy at the chromosomal nucleolus organizer region, indicating that a considerable quantity of the enzyme remains bound to the rRNA genes. From this we conclude that rRNA genes loaded with polymerase I molecules are transmitted from one cell generation to the next one and that factors other than the polymerase itself are involved in the modulation of transcription of DNA containing rRNA genes during the cell cycle. KW - nucleolus KW - nucleolus organizer KW - fibrillar centers KW - rRNA genes KW - anti-RNA polymerase I antibodies Y1 - 1984 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-33223 ER - TY - CHAP A1 - Scheer, Ulrich A1 - Franke, Werner W. T1 - Transcriptional complexes of nucleolar genes N2 - No abstract available Y1 - 1976 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-41072 ER - TY - CHAP A1 - Scheer, Ulrich T1 - Electron microscopic analysis of chromatin and gene expression N2 - No abstract available Y1 - 1982 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-39456 ER - TY - CHAP A1 - Schartl, Manfred A1 - Mäueler, Winfried A1 - Raulf, Friedrich A1 - Robertson, Scott M. T1 - Molecular aspects of melanoma formation in Xiphophorus N2 - No abstract available. KW - Schwertkärpfling KW - Krebs Y1 - 1988 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-72689 ER - TY - CHAP A1 - Schartl, A. A1 - Schartl, Manfred A1 - Anders, F. T1 - Phenotypic conversion of malignant melanoma to benign melanoma and vice versa in Xiphophorus N2 - No abstract available. KW - Schwertkärpfling KW - Krebs Y1 - 1981 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-86662 ER - TY - CHAP A1 - Sanusi, Khaleel Asyraaf Mat A1 - Klemke, Roland T1 - Immersive Multimodal Environments for Psychomotor Skills Training T2 - Proceedings of the 1st Games Technology Summit N2 - Modern immersive multimodal technologies enable the learners to completely get immersed in various learning situations in a way that feels like experiencing an authentic learning environment. These environments also allow the collection of multimodal data, which can be used with artificial intelligence to further improve the immersion and learning outcomes. The use of artificial intelligence has been widely explored for the interpretation of multimodal data collected from multiple sensors, thus giving insights to support learners’ performance by providing personalised feedback. In this paper, we present a conceptual approach for creating immersive learning environments, integrated with multi-sensor setup to help learners improve their psychomotor skills in a remote setting. KW - immersive learning technologies KW - multimodal learning KW - sensor devices KW - artificial intelligence KW - psychomotor training Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-246016 ER - TY - CHAP A1 - Sagelsdorff, P. A1 - Lutz, Werner K. T1 - Sensitivity of DNA and nucleotides to oxidation by permanganate and hydrogen peroxide N2 - no abstract available KW - Toxikologie Y1 - 1987 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-80062 ER - TY - CHAP A1 - Ruhe, Ernstpeter T1 - Tristan et Iseut dans l'espace: A propos d'un poème de Pierre Garnier N2 - No abstract available Y1 - 1987 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-34074 ER - TY - CHAP A1 - Ruhe, Ernstpeter T1 - Pour faire la lumiere as lais? Mittelalterliche Handbücher des Glaubenswissens und ihr Publikum. N2 - No abstract available KW - Fachliteratur KW - Geschichte 1100-1600 KW - Wissensorganisation KW - Lehrdichtung KW - Wissensliteratur Y1 - 1987 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-36805 ER - TY - CHAP A1 - Ruhe, Ernstpeter T1 - Der chevalier errant auf enzyklopädischer Fahrt N2 - No abstract available Y1 - 1984 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-33722 ER - TY - CHAP A1 - Ruhe, Ernstpeter T1 - Les plumes du paon et le mouton assimilé: Zum Problem der Originalität im Mittelalter. N2 - No abstract available Y1 - 1985 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-36872 ER - TY - CHAP A1 - Ruhe, Ernstpeter T1 - Inventio devenue troevemens: La recherche de la matière au moyen âge. N2 - No abstract available Y1 - 1984 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-36816 ER - TY - CHAP A1 - Ruhe, Ernstpeter T1 - La peur de la transgression: A propos du Livre d'Enanchet et du Bestiaire d'amours. N2 - No abstract available Y1 - 1984 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-36841 ER - TY - CHAP A1 - Ruhe, Ernstpeter T1 - Literatur und Zeitgeschichte. Der algerische Roman seit der Unabhängigkeit N2 - No abstract available Y1 - 1991 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-33875 ER - TY - CHAP A1 - Ruhe, Ernstpeter T1 - De Nedjma à Nedschma: Il y a trente ans, la critique allemande découvrait une nouvelle comète N2 - No abstract available Y1 - 1993 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-33857 ER - TY - CHAP A1 - Ruhe, Ernstpeter T1 - Repetition und Integration: Strukturprobleme des 'Roman de Tristan en prose' N2 - No abstract available Y1 - 1979 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-33610 ER - TY - CHAP A1 - Ruhe, Ernstpeter T1 - Aimé Césaire et Janheinz Jahn. Un dialogue important pour le théâtre césairien N2 - No abstract available Y1 - 1987 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-33714 ER - TY - CHAP A1 - Ruhe, Ernstpeter T1 - Thesen zum Ende der Gattungsgeschichte des höfischen Romans N2 - No abstract available Y1 - 1979 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-33626 ER - TY - CHAP A1 - Ruhe, Ernstpeter T1 - L'Anticlaudelianus d'Aimé Césaire: Intertextualité dans 'Et les chiens se taisaient' N2 - No abstract available Y1 - 1994 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-38220 ER - TY - CHAP A1 - Riehl, Rüdiger A1 - Schartl, Manfred A1 - Anders, Fritz T1 - An ultrastructural study of melanoma in Xiphophorus N2 - Melanotic melanoma (MM) of Xiphophorus (Teleostei: Poeciliidae) was studied by conventional preparations and freeze-etch preparations for electron microscopy. MM of Xiphophorus exhibits tightly packed pigment cells with prominent dendritic processes and interdigitations of their plasma membranes. The most impressive feature of MM cells is the occurrence of Iarge lobulated nuclei with numerous nuclear pores and some nuclear pockets. Abundant spheroidal or ellipsoidal melanosomes (diameter 200-650 nm) and vesicular structures are distributed throughout the cellular dendrites, whereas the perinucJear cytoplasm is free of melanosomes. A further characteristic feature of melanoma cells in fish is the occurrence of melanosome complexes (i.e., "compound melanosomes"). These melanosome complexes consist of a few to numerous melanosomes, which are enveloped by a separate rnembrane. Pinocytotic vesicles couJd be demonstrated with distinct differences in frequency and distribution patterns, indicating differences in the metabolic activities of the cells in the same melanoma. Intercellular junctions are lacking in the MM cells. The conventional TEM technique showed clear advantages in the demonstration of intemal architecture of organelles, whereas FE bad considerable potential in respect to the visualization of membrane surface specializations. KW - Schwertkärpfling KW - Krebs KW - Ultrastruktur Y1 - 1985 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-70978 ER - TY - CHAP A1 - Rethwilm, Axel A1 - Baunach, Gerald A1 - Mori, Kazuyasu A1 - ter Meulen, Volker T1 - Transactivation of HIV by human spumaretrovirus N2 - To study the activation of HIV by human spumaretrovirus (HSRV) the long terminal repeats (LTRs) of HSRV, HIVl and HIV2 were examined with respect to their ability to function as transcriptional promoters in virus infected and uninfected cells. Transient transfections using plasmids in which the L TRs of the three viruses were coupled to the bacterial chloramphenicol acetyltransferase (CA T) gene revealed (i) the level of cat gene expression directed by the HSRV LTR was markedly increased in HSRV infected cells compared to uninfected cells, (ii) cat gene expression driven by the HIV1 LTR, but not by the HIV2 LTR could be enhanced upon HSRV infection, whereas (iii) neither in HIV1 nor in HIV2 infected cells an effect on HSRV LTR driven cat geneexpression was detected. KW - HIV Y1 - 1990 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-86436 ER - TY - CHAP A1 - Peter, R. U. A1 - Schartl, Manfred A1 - Anders, F. A1 - Duncker, H.-R. T1 - Pigment pattern formation during embryogenesis in Xiphophorus N2 - No abstract available. KW - Schwertkärpfling KW - Embryonalentwicklung KW - Pigmentmuster Y1 - 1985 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-69370 ER - TY - CHAP A1 - Mori, Kazuyasu A1 - Rethwilm, Axel A1 - Schwinn, Andreas A1 - Horak, Ivan T1 - Replication of human immunodeficiency virus type 1 in human t-cells expressing antisense RNA N2 - No abstract available. KW - HIV Y1 - 1990 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-86426 ER - TY - CHAP A1 - Moch, Thomas A1 - Hoschützky, Heinz A1 - Hacker, Jörg A1 - Krönke, Klaus-D. A1 - Jann, Klaus T1 - Isolation and characterization of the \(\alpha\)-Sialyl-\(\beta\) 2-3-Galactosyl (S)-Specific Adhesin fimbriated Escherichia coli N2 - The \(\alpha\)-Sialyl-\(\beta\) 2-3-Galactosyl-specific adhesin (S adhesin) was isolated from cells of a recombinant Escherichia coli K-12 strain expressing the S-flmbrial adhesin complex. A crude cell extract was partiaUy dissociated into fimbriae and an adhesin-enriched fraction by heating to 7O°C. From the latter, adhesin was purified to apparent homogeneity (by fast protein liquid chromatography, immunoblot, and NaDodSO\(_4\)/PAGE) by differential ammonium sulfate precipitation, dissociation in 8 M guanidine hydrochloride, and high-resolution anion-exchange chromatography in 8 M urea. The purified adhesin formed an aggregate of M\(_r\)\(\approx\)10\(^6\) that was made up of one type of 12-kDa polypeptide (fimbrillin is 16.5 kDa). It had pI value of 4.7 (fimbriae has a pI value of 6). Adhesin and fimbrillin had different amino add compositions. The purified adhesins agglutinated human and bovine erythrocytes with the same speclfkity as the whole bacteria; purified fimbriae were not adhesive. Monoclonal anti-adhesin and anti-fimbriae antibodies were obtained. Monoclonal antiadhesin, but none of the anti-fimbriae, antibodies inhibited the agglutination of erythrocytes. The anti-adhesive antibodies were used in immuno-gold electron microscopy to localize adhesin exclusively on the fimbriae, with a possible preference to their tips. Y1 - 1987 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-40330 ER - TY - CHAP A1 - Maurer, B. A1 - Bannert, H. A1 - Rethwilm, Axel A1 - Darai, B. A1 - Flügel, R. M. T1 - Characterization of the env gene and of two novel coding regions of the human spumaretrovirus N2 - Recombinant clones harboring retroviral DNA were established. The nucleotide sequence of the central and 3' region of the genome of the human spumaretrovirus was determined. The 5' end of the deduced protein sequence was homologaus to the endonuclease domain of retroviral reverse transcriptases. A small intergenic region is followed by a lang open reading frame of 985 aminoacid residues that according to its genomic location and structural features is a typical retroviral env gene. Surprisingly, the postenv region contains two open reading frames that encodes two novel retroviral genes, termed bel-l and bel-2. The 3' LTR is 963 nucleotides lang and contains the signal sequences characteristic for transcriptional regulation of retrovirus genomes. KW - Spumaviren Y1 - 1988 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-86334 ER - TY - CHAP A1 - Marohn, Frank T1 - On testing the exponential and Gumbel distribution N2 - No abstract available KW - Gumbel-Verteilung KW - Extremal–I–Verteilung KW - generalized Pareto distribution KW - extreme value distribution Y1 - 1994 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-45804 ER - TY - CHAP A1 - Mahsberg, Dieter T1 - Brood care and family cohesion in the tropical scorpion Pandinus imperator (Koch) (Scorpiones: Scorpionidae) N2 - Pandinus imperator is a forest dweller of tropical West Africa. In the field, lobserved aggregations of up to 15 individuals. In the laboratory, mixed age groups of related and also unrelated animals lived jointly in terraria rarely showing within-group aggression or cannibalism. Brood-caring behavior of the mother influenced growth rate and survival probability of the young. With birth, mothers became very aggressive. To study family cohesion in Pandinus, experiments with family groups were conducted. Siblings aggregated around their mother. In choice experiments with two family groups, mothers were placed in enclosures that only the young were able to enter or to leave. Second instars significantly preferred the enclosure containing their own mother. Aggression among unrelated young of the same age was not observed. Feeding experiments studied the possible advantages of long-Iasting group living with regard to enhanced success in prey capture and its effect on growth of the young. Even groups of second instars were unable to subdue large prey on their own. Sibling groups with their mother removed suffered high mortality due to starvation and cannibalism compared to groups with mothers present. Here, young grew significantly faster: they shared the prey that only the mother was able to kill and dismember. Pandinus imperator has to be considered an intermediate subsocial scorpion. KW - Skorpion Y1 - 1990 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-45776 ER - TY - CHAP A1 - Macht, Michael T1 - Kovariation und Dissoziation psychophysiologischer Variablen unter kurzzeitig verminderter Energiezufuhr N2 - no abstract available KW - Psychologie KW - Medizinische Psychologie KW - Kongress KW - Magdeburg <1994> KW - Physiologische Psychologie Y1 - 1994 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-80187 ER - TY - CHAP A1 - Lutz, Werner K. A1 - Schlatter, C. T1 - Extrapolation of carcinogenicity data to low doses with a dose-response study of the binding of benzo(a)pyrene to rat liver DNA N2 - The binding of tritiated benzo(a)pyrene (BP) to liver DNA of 25 adult male rats (SIV 50) has been determined 50 h after a single intraperitoneal injection of doses between 40 ug/kg and 4; mg/kg. The dose-response relations~ ip is linear up to i mg/kg, shows a sigmoid step towards 2 mg/kg and a shallow linear. slope above that value. TlJe 0 bserved bin ding ranges from 1.7 to 180 nmoles BP per mole DNA phosphate. The non-linearity between 1 and 2 mg/kg could be explained 0):1 the basis of an induction of metabolizing enzymes. A pure1y mathematical extrapolation of therumour incidence from a carcinogenic dose (1 x 40mg/kg for a 20% hepatoma incidence in newborn mice) to human exposure levels (aboilt 0.1 ug/kg per day) would never have followed a step like the on~ found in our experiments. Our dose-effect study therefore shows how carcinogenitity data could be extrapolated in a biologically founded way to low doses. KW - Toxikologie Y1 - 1978 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-80157 ER - TY - CHAP A1 - Lutz, Werner K. T1 - Quantitative evaluation of DNA-binding data in vivo for low-dose extrapolations N2 - no abstract available KW - Toxikologie Y1 - 1987 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-80079 ER - TY - CHAP A1 - Lutz, Werner K. T1 - Structural characteristics of compounds that can be activated to chemically reactive metabolites: use for a prediction of a carcinogenic potential N2 - Many mutagens and carcinogens act via covalent interaction of metabolic intermediates with DNA in the target cell. This report groups those structural elements which are often found to form the basis for a metabolism to such chemically reactive metabolites. ~mpounds which are chemically reactive per se and which do not require metabolic activation form group 1. Group 2 compri~es of olefins and aromatic hydrocarbons where the oxidation via an epoxide can be responsible for the generation of reactive species. Aromatic amines, hydrazines, and nitrosamirres form group 3 requiring an oxidation of a nitrogen atom or of a carbon atom in alpha position to a nitrosated amine. Group 4 compounds are halogenated hydrocarbons which can either give rise to radicals or can form an ·olefin (group 2) upon dehydrohalogenation. Group 5 compounds depend upon some preceding enzymatic activity either not available in the target cell or acting on positions in the molecule which are not directly involved in the subsequent formation of electrophilic atoms. Examples for each group are taken from the "List of Chemieals and Irrdustrial Processes Associated with Cancer in Humans" as compiled by the International Agency for the Research on Cancer, and it is shown that 91% of the organic carcinogens would have been detected on the basis of structural elements characteristic for group 1-5. As opposed to this very high sensitivity, the specificity ( the true negative fraction) of using this approach as a short-term test for carcinogenicity is shown to be bad because detoxification pathways have so far not been taken into account. These competing processes are so complex, however, that either only very extensive knowledge about pharmacokinetics, stability, and reactivity will be required or that in vivo systems have to be used to predict, on a quantitative basis, the darnage expected on the DNA. DNA-binding experiments in vivo are presented with benzene and toluene to demonstrate one possible way for an experimental assessment and it is shown that the detoxification reaction at the methyl group available only in toluene gives rise to a reduction by at least a factor of forty for the binding to rat liver DNA. This quantitative approach available with DNA-binding tests in vivo, also allows evaluation as to whether reactive metabolites and their DNA binding are always the most important single activities contributing to the overall carcinogenicity of a chemical. With the example of the livertumor inducing hexachlorocyclohexane isomers it is shown that situations will be found where reactive metabolites are formed and DNA binding in vivo is measurable but where this activity cannot be the decisive mode of carcinogenic action. It is concluded that the lack of structural elements known to become potentially reactive does not guarantee the lack of a carcinogenic potential. KW - Toxikologie KW - Structureactivity relationship KW - Reactive intermediates KW - Metabolic activation KW - DNA Binding KW - Covalent binding index KW - Carcinogens KW - Benzene Y1 - 1984 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-80105 ER - TY - CHAP A1 - Kurtz, Beth A1 - Schneider, Wolfgang A1 - Borkowski, John G. A1 - Carr, Martha A1 - Turner, Lisa A. T1 - Sources of memory and metamemory development: Societal, parental, and educational influences N2 - This project had two goals: (1) to examine the impact of strategy training on memory performance in German and American children, and (2) to search for environmental correlates of individual differences in cognitive processes. Following pretesting, 437 children were divided into training and control groups, with the former receiving training in clustering strategies. Trained children showed sizable strategy maintenance and transfer effects two weeks and six months later. Parents and teachers completed questionnaires about the teaching of strategies and their attributional beliefs about children's academic successes and failures. The differences in strategie behavior and attributions of German and American children were due, in part, to differences in strategy-enriched environments. KW - Psychologie Y1 - 1988 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-50524 ER - TY - CHAP A1 - Kuhn, Dieter T1 - Emperor Huizong’s (r. 1100-1126): Short-lived Earthly Paradise N2 - Zhao Ji (1082-1135), better known as Emperor Huizong (r. 1100-1126) of the Southern Song Dynasty (960-1127) gained a reputation as supreme perfectionist as artist, art collector and connoisseur, a ruler devoted to the faith of Daoism, squandering a fortune on building palaces and halls and on landscape gardening. A famous example of his costly ‘folie de grandeur’ is the Sacred Northeast Mountain Peak Genyue, a gigantic rock garden in the northeast part of the Old City of the capital Kaifeng. The garden is described in sources such as the Huayanggong jishi (Description of the Florescent Solitary Palace) by the Buddhist monk Zu Xiu from 1127 and Zhang Hao’s (ca. 1180-1250) Genyue ji (Record of the Northeast Marchmount). The project in search of auspicious blessing started in 1118, having originated in the emperor’s conviction that the Daoist Immortals would descend to this exquisite paradise situated in the centre of the world, his capital. In his conviction the landscape garden that exceeded nature’s beauty would prolong and glorify his rule for ten thousand years. The Genyue was completed in January 1123, and thus became part of Emperor Huizong’s Divine Empyrean Daoist ideology of statecraft. Contrary to all auspicious symbolism, the Song’s emblematic demonstrations of power, and the necessity to meet political expectations, Emperor Huizong proved incapable of finding a solution to the disastrous situation at the northern frontier with Jin troupes moving onto his capital. Completed in 1123 the Genyue Marchmount was destroyed in the cold winter of 1126/1127 by the inhabitants of Kaifeng in their desperate struggle for survival in their besieged town. KW - China KW - Genyue ji KW - Song Huizong KW - Kaifeng KW - Landschaftsgarten KW - Südliche Songdynstie KW - Huayanggong jishi KW - Kaiser Huizong Y1 - 2014 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-106115 ER - TY - CHAP A1 - Krüger, Hans-Peter A1 - Rausche, A. T1 - Die Prüfung von Verlaufskurven auf das Vorliegen von Trends über die exakte Verteilung von Spearman's S N2 - no abstract available KW - Psychologie Y1 - 1980 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-79827 ER - TY - CHAP A1 - Krüger, Hans-Peter A1 - Kohnen, Ralph T1 - Evaluierung gruppentherapeutischer Situationen durch physiologische Parameter und Selbsteinschätzungen N2 - No abstract available Y1 - 1980 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-40971 ER - TY - CHAP A1 - Krüger, Hans-Peter A1 - Kohnen, Ralph T1 - Kognitive, emotionale und physiologische Determinanten sozialer Zustände N2 - The psychological and physiological effects of a socially oriented sensitivity training were evaluated. It is shown that decreased physical distance as well as increased intimacy yields high activation, both in psychological measures (experienced stress) and in pulse frequences. One result (highly significant and replicated in other experiments) was paradoxical: when Ss had to caress the face of a heterosexual vis-a-vis, they reported high experienced stress, but pulse frequences dropped rapidely below the resting pulse. Some suggestions are made to explain these findings. The question arises whether an autonomic somatic process, induced by social Stimulation, but independent of the cognitive coping is responsible for these results. KW - Psychologie Y1 - 1981 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-86055 ER - TY - CHAP A1 - Krüger, Hans-Peter A1 - Kohnen, Ralf A1 - Lienert, Gustav A. T1 - Drei Forderungen zur Prüfung der Homogenität von Zentren bei Multicenter-Studien N2 - Es wird argumentiert, daß bei der Prüfung der Homgenität von Zentren in mehrfaktoriellen Multicenter-Studien vor allem entscheidend ist, daß sich die Zentren in den faktoriellen Variablen nicht unterscheiden, deren Effekte in der späteren Auswertung interpretiert werden sollen. Dazu wird folgendes Procedere vorgeschlagen: (1) überprüfe, ob in allen Zentren die Randomisierungsbedingungen eingehalten wurden, (2) überprüfe, ob die Zentren homogen bezogen auf die eingebrachten Schichtvariablen (z.B. Geschlecht, Indikation) sind und (3) überprüfe, ob die Zentren homogen sind bezogen auf die Wechselwirkungen zwischen den eingebrachten faktoriellen Variablen. Es wird gezeigt, daß vor allem Forderung (3) für die Interpretationsfähigkeit der Ergebnisse von entscheidender Bedeutung ist. Möglichkeiten der statistischen Prüfung dieser Voraussetzungen werden an einem Beispiel aus der klinischen Prüfung eines Psychopharmakons vorgestellt. KW - Psychologie Y1 - 1981 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-101730 ER - TY - CHAP A1 - Krüger, Hans-Peter A1 - Heller, Dieter T1 - Psychomotorische Effekte von Alkohol N2 - No abstract available. KW - Psychomotorik KW - Alkohol Y1 - 1989 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-87079 ER - TY - CHAP A1 - Krüger, Hans-Peter A1 - Gold, Rainer A1 - Hüppe, A. T1 - Coergisms between drugs and alcohol - a psychopharmacological review N2 - No abstract available. KW - Rauschgift KW - Alkohol Y1 - 1993 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-69850 ER - TY - CHAP A1 - Krüger, Hans-Peter T1 - Selbst- und Fremdbeurteilung in Diagnostik und Psychotherapie N2 - No abstract available KW - Klinische Psychologie KW - Psychotherapie Y1 - 1980 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-40964 ER - TY - CHAP A1 - Krüger, Hans-Peter T1 - Was ist Sprechen? - objektive Registrierung des Sprechverhaltens im Alltag mit dem Logoport N2 - No abstract available Y1 - 1984 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-41266 ER - TY - CHAP A1 - Krüger, Hans-Peter T1 - Die Selbst- und Fremdbeurteilung als Resultante sozialer Erfahrung N2 - No abstract available KW - Selbsteinschätzung Y1 - 1979 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-86039 ER - TY - CHAP A1 - Krüger, Hans-Peter T1 - Interaction - toward a precise understanding of a scientific term N2 - No abstract available. KW - Interaktion Y1 - 1993 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-87088 ER - TY - CHAP A1 - Krüger, Hans-Peter T1 - Effects of low alcohol dosages: A review of the literature N2 - No abstract available. KW - Blutalkohol Y1 - 1993 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-69843 ER -