TY  - JOUR
A1  - Gorboulev, Valentin
A1  - Akhundova, Aida
A1  - Luzius, Heike
A1  - Fahrenholz, Falk
T1  - Molecular cloning of substance P receptor cDNA from guinea-pig uterus
N2  - A cDNA encoding guinea-pig uterine substance P (SP) receptor has been isolated using the homology screening approach. Northern blot analysis reveals that the corresponding mRNA, of approx. 4.8 kb, is expressed in all tissues tested, but predominantly in the uteri of non-pregnant animals; during pregnancy its expression is reduced. The guinea-pig SP receptor was expressed in COS-7 cells and demonstrated relative Iigand affinity in the order: SP >> neurokinin A > neurokinin B.
KW  - Biologie
KW  - Substance P receptor
KW  - G-protein-coupled receptor
KW  - Guinea-pig uterus
KW  - COS cell expression
Y1  - 1992
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-59293
ER  -