TY  - JOUR
A1  - Nell, Manuel
A1  - Burgkart, Rainer H.
A1  - Gradl, Guntmar
A1  - von Eisenhart-Rothe, Rüdiger
A1  - Schaeffeler, Christoph
A1  - Trappe, Dennis
A1  - Prazeres da Costa, Clarissa
A1  - Gradinger, Reiner
A1  - Kirchhoff, Chlodwig
T1  - Primary extrahepatic alveolar echinococcosis of the lumbar spine and the psoas muscle
JF  - Annals of Clinical Microbiology and Antimicrobials
N2  - Alveolar echinococcosis (AE) of human being caused by Echinococcus multilocularis is a rare but important zoonosis especially in tempered zones of middle Europe and Northern America with endemic character in many countries. Due to the long incubation period, various clinical manifestations, critical prognosis, and outcome AE presents a serious and severe disease. The primary focus of infection is usually the liver. Although secondary affection of visceral organs is possible extrahepatic AE is highly uncommon. Moreover, the involvement of bone and muscle presents with an even lower incidence. In the literature numerous cases on hepatic AE have been reported. However, extrahepatic AE involving bones and/or muscles was described very rarely. We report a case of an 80-year-old man with primary extrahepatic alveolar Echinococcosis of the lumbar spine and the psoas muscle. The etiology, diagnosis, differential diagnoses, treatment options and outcome of this rare disease are discussed in context with the current literature.
KW  - Medicine
Y1  - 2011
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-141796
VL  - 10
IS  - 13
ER  - 
TY  - JOUR
A1  - Holzapfel, Boris Michael
A1  - Chhaya, Mohit Prashant
A1  - Melchels, Ferry Petrus Wilhelmus
A1  - Holzapfel, Nina Pauline
A1  - Prodinger, Peter Michael
A1  - von Eisenhart-Rothe, Rüdiger
A1  - Griensven, Martijn van
A1  - Schantz, Jan-Thorsten
A1  - Rudert, Maximilian
A1  - Hutmacher, Dietmar Werner
T1  - Can Bone Tissue Engineering Contribute to Therapy Concepts after Resection of Musculoskeletal Sarcoma?
JF  - Sarcoma
N2  - Resection of musculoskeletal sarcoma can result in large bone defects where regeneration is needed in a quantity far beyond the normal potential of self-healing. In many cases, these defects exhibit a limited intrinsic regenerative potential due to an adjuvant therapeutic regimen, seroma, or infection. Therefore, reconstruction of these defects is still one of the most demanding procedures in orthopaedic surgery. The constraints of common treatment strategies have triggered a need for new therapeutic concepts to design and engineer unparalleled structural and functioning bone grafts. To satisfy the need for long-term repair and good clinical outcome, a paradigm shift is needed from methods to replace tissues with inert medical devices to more biological approaches that focus on the repair and reconstruction of tissue structure and function. It is within this context that the field of bone tissue engineering can offer solutions to be implemented into surgical therapy concepts after resection of bone and soft tissue sarcoma. In this paper we will discuss the implementation of tissue engineering concepts into the clinical field of orthopaedic oncology.
KW  - musculoskeletal sarcoma
Y1  - 2013
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-132465
VL  - 2013
IS  - Article ID 153640
ER  -