TY  - JOUR
A1  - Franzek, E.
A1  - Stöber, Gerald
A1  - Beckmann, H.
T1  - Malignes neuroleptisches und lebensbedrohliches katatones Syndrom: Eine identische Komplikation im Verlauf von funktionellen Psychosen
T1  - Malignant neuroleptic syndrome and lethai catatonia: an identical complication in functional psychoses
N2  - no abstract available
KW  - Neuropsychiatrie
KW  - Malignes neuroleptisches Syndrom
KW  - akut lebensbedrohlich katatones Syndrom
KW  - perniziöse Katatonie
KW  - zykloide Psychose
KW  - Malignant neuroleptic syndrome
KW  - Iife threatening catatonic syndrome
KW  - lethai catatonia
KW  - cycloid psychosis
Y1  - 1994
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-82243
ER  - 
TY  - JOUR
A1  - Lesch, K. P.
A1  - Stöber, Gerald
A1  - Balling, U.
A1  - Franzek, Ernst
A1  - Li, S. H.
A1  - Ross, C. A.
A1  - Newman, M.
A1  - Beckmann, H.
A1  - Riederer, P.
T1  - Triplet repeats in clinical subtypes of schizophrenia: variation at the DRPLA (B37 CAG repeat) locus is not associated with periodic catatonia
N2  - Clinical evidence for a dominant mode of inheritance and anticipation in periodic catatonia, a distinct subtype of schizophrenia, indicates that genes with triplet repeat expansions or other unstable repetitive elements affecting gene expression may be involved in the etiology of this disorder. Because patients affected with dentatorubral-pallidoluysian atrophy (DRPLA) may present with "schizophrenic" symptoms, we have investigated the DRPLA (B 37 CAG repeat) locus on chromosome 12 in 41 patients with periodic catatonia. The B 37 CAG repeat locus was highly polymorphic but all alleles in both the patient and control group had repeat sizes within the normal range. We conclude that variation at the DRPLA locus is unlikely to be associated with periodic catatonia. The evidence for dominant inheritance and anticipation as well as the high prevalence of human brain genes containing trinucleotide repeats justifies further screening for triplet repeat expansions in periodic catatonia.
KW  - Schizophrenie
KW  - Association study
KW  - B 37 CAG repeat locus
KW  - chromosome 12
KW  - schizophrenia
KW  - periodic catatonia
Y1  - 1994
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-63369
ER  -