TY - JOUR A1 - Um, Jaegon A1 - Hinrichsen, Haye A1 - Kwon, Chulan A1 - Park, Hyunggyu T1 - Total cost of operating an information engine JF - New Journal of Physics N2 - We study a two-level system controlled in a discrete feedback loop, modeling both the system and the controller in terms of stochastic Markov processes. We find that the extracted work, which is known to be bounded from above by the mutual information acquired during measurement, has to be compensated by an additional energy supply during the measurement process itself, which is bounded by the same mutual information from below. Our results confirm that the total cost of operating an information engine is in full agreement with the conventional second law of thermodynamics. We also consider the efficiency of the information engine as a function of the cycle time and discuss the operating condition for maximal power generation. Moreover, we find that the entropy production of our information engine is maximal for maximal efficiency, in sharp contrast to conventional reversible heat engines. KW - wrath KW - information engine KW - mutual information KW - fluctuation theorem KW - Maxwell demon KW - Szilárd KW - efficiency KW - maximum power Y1 - 2015 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-148286 VL - 17 IS - 085001 ER - TY - JOUR A1 - Nedopil, Alexander J. A1 - Dhaliwal, Anand A1 - Howell, Stephen M. A1 - Hull, Maury L. T1 - A surgeon that switched to unrestricted kinematic alignment with manual instruments has a short learning curve and comparable resection accuracy and outcomes to those of an experienced surgeon JF - Journal of Personalized Medicine N2 - After starting an orthopedic practice, a surgeon with a fellowship in mechanically aligned (MA) TKA initiated this study to characterize their learning curve after they switched to unrestricted kinematic alignment (KA) TKA using manual instruments. Accordingly, the present study determined for the inexperienced (IE) surgeon the number of cases required to achieve consistent femoral resections and operating times, and whether the femoral resection accuracy, patient-reported outcome measures (PROMs), and component alignment were different from an experienced (E) surgeon. This prospective cohort study analyzed the IE surgeon's first 30 TKAs, all performed with KA, and 30 consecutive KA TKAs performed by an E surgeon. The resection accuracy or deviation was the calipered thickness of the distal and posterior medial and lateral femoral resections minus the planned resection thickness, which was the thickness of the corresponding condyle of the femoral component, minus 2 mm for cartilage wear, and 1 mm for the kerf of the blade. Independent observers recorded the femoral resection thickness, operative times, PROMs, and alignment. For each femoral resection, the deviation between three groups of patients containing ten consecutive KA TKAs, was either insignificant (p = 0.695 to 1.000) or within the 0.5 mm resolution of the caliper, which indicated no learning curve. More than three groups were needed to determine the learning curve for the operative time; however, the IE surgeon's procedure dropped to 77 min for the last 10 patients, which was 20 min longer than the E surgeon. The resection deviations of the IE and E surgeon were comparable, except for the posterolateral femoral resection, which the IE surgeon under-resected by a mean of −0.8 mm (p < 0.0001). At a mean follow-up of 9 and 17 months, the Forgotten Joint Score, Oxford Knee Score, KOOS, and the alignment of the components and limbs were not different between the IE and E surgeon (p ≥ 0.6994). A surgeon that switches to unrestricted KA with manual instruments can determine their learning curve by computing the deviation of the distal and posterior femoral resections from the planned resection. Based on the present study, an IE surgeon could have resection accuracy, post-operative patient outcomes, and component alignment comparable to an E surgeon. KW - total knee arthroplasty KW - kinematic alignment KW - learning curve KW - accuracy KW - efficiency Y1 - 2022 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-281842 SN - 2075-4426 VL - 12 IS - 7 ER -