TY - JOUR A1 - Patzer, Theresa Sophie A1 - Kunz, Andreas Steven A1 - Huflage, Henner A1 - Conrads, Nora A1 - Luetkens, Karsten Sebastian A1 - Pannenbecker, Pauline A1 - Paul, Mila Marie A1 - Ergün, Süleyman A1 - Bley, Thorsten Alexander A1 - Grunz, Jan-Peter T1 - Ultrahigh-resolution photon-counting CT in cadaveric fracture models: spatial frequency is not everything JF - Diagnostics N2 - In this study, the impact of reconstruction sharpness on the visualization of the appendicular skeleton in ultrahigh-resolution (UHR) photon-counting detector (PCD) CT was investigated. Sixteen cadaveric extremities (eight fractured) were examined with a standardized 120 kVp scan protocol (CTDI\(_{vol}\) 10 mGy). Images were reconstructed with the sharpest non-UHR kernel (Br76) and all available UHR kernels (Br80 to Br96). Seven radiologists evaluated image quality and fracture assessability. Interrater agreement was assessed with the intraclass correlation coefficient. For quantitative comparisons, signal-to-noise-ratios (SNRs) were calculated. Subjective image quality was best for Br84 (median 1, interquartile range 1–3; p ≤ 0.003). Regarding fracture assessability, no significant difference was ascertained between Br76, Br80 and Br84 (p > 0.999), with inferior ratings for all sharper kernels (p < 0.001). Interrater agreement for image quality (0.795, 0.732–0.848; p < 0.001) and fracture assessability (0.880; 0.842–0.911; p < 0.001) was good. SNR was highest for Br76 (3.4, 3.0–3.9) with no significant difference to Br80 and Br84 (p > 0.999). Br76 and Br80 produced higher SNRs than all kernels sharper than Br84 (p ≤ 0.026). In conclusion, PCD-CT reconstructions with a moderate UHR kernel offer superior image quality for visualizing the appendicular skeleton. Fracture assessability benefits from sharp non-UHR and moderate UHR kernels, while ultra-sharp reconstructions incur augmented image noise. KW - photon-counting KW - tomography KW - X-ray computed KW - fracture KW - cancellous bone KW - convolution kernel Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-319281 SN - 2075-4418 VL - 13 IS - 10 ER -