TY  - JOUR
A1  - Jung‐König, Mona
A1  - Füllenbach, Christoph
A1  - Murphy, Michael F.
A1  - Manzini, Paola
A1  - Laspina, Stefan
A1  - Pendry, Kate
A1  - Mühling, Jörg
A1  - Wikman, Agneta
A1  - Humbrecht, Catherine
A1  - Rigal, Jean‐Christophe
A1  - Lasocki, Sigismond
A1  - Folléa, Gilles
A1  - Seifried, Erhard
A1  - Müller, Markus M.
A1  - Geisen, Christof
A1  - Aranko, Kari
A1  - Zacharowski, Kai
A1  - Meybohm, Patrick
T1  - Programmes for the management of preoperative anaemia: audit in ten European hospitals within the PaBloE (Patient Blood Management in Europe) working group
JF  - Vox Sanguinis
N2  - Background and objectives
Preoperative anaemia is an independent risk factor for a higher morbidity and mortality, a longer hospitalization and increased perioperative transfusion rates. Managing preoperative anaemia is the first of three pillars of Patient Blood Management (PBM), a multidisciplinary concept to improve patient safety. While various studies provide medical information on (successful) anaemia treatment pathways, knowledge of organizational details of diagnosis and management of preoperative anaemia across Europe is scarce.

Materials and methods
To gain information on various aspects of preoperative anaemia management including organization, financing, diagnostics and treatment, we conducted a survey (74 questions) in ten hospitals from seven European nations within the PaBloE (Patient Blood Management in Europe) working group covering the year 2016.

Results
Organization and activity in the field of preoperative anaemia management were heterogeneous in the participating hospitals. Almost all hospitals had pathways for managing preoperative anaemia in place, however, only two nations had national guidelines. In six of the ten participating hospitals, preoperative anaemia management was organized by anaesthetists. Diagnostics and treatment focused on iron deficiency anaemia which, in most hospitals, was corrected with intravenous iron.

Conclusion
Implementation and approaches of preoperative anaemia management vary across Europe with a primary focus on treating iron deficiency anaemia. Findings of this survey motivated the hospitals involved to critically evaluate their practice and may also help other hospitals interested in PBM to develop action plans for diagnosis and management of preoperative anaemia.
KW  - iron deficiency
KW  - patient blood management
KW  - preoperative anaemia management
Y1  - 2020
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-214049
VL  - 115
IS  - 3
SP  - 182
EP  - 191
ER  - 
TY  - JOUR
A1  - Schmitt, Elke
A1  - Meybohm, Patrick
A1  - Neef, Vanessa
A1  - Baumgarten, Peter
A1  - Bayer, Alexandra
A1  - Choorapoikayil, Suma
A1  - Friederich, Patrick
A1  - Friedrich, Jens
A1  - Geisen, Christof
A1  - Güresir, Erdem
A1  - Grünewald, Matthias
A1  - Gutjahr, Martin
A1  - Helmer, Philipp
A1  - Herrmann, Eva
A1  - Müller, Markus
A1  - Narita, Diana
A1  - Raadts, Ansgar
A1  - Schwendner, Klaus
A1  - Seifried, Erhard
A1  - Stark, Patrick
A1  - Steinbicker, Andrea U.
A1  - Thoma, Josef
A1  - Velten, Markus
A1  - Weigt, Henry
A1  - Wiesenack, Christoph
A1  - Wittmann, Maria
A1  - Zacharowski, Kai
A1  - Piekarski, Florian
T1  - Preoperative anaemia and red blood cell transfusion in patients with aneurysmal subarachnoid and intracerebral haemorrhage - a multicentre subanalysis of the German PBM Network Registry
JF  - Acta Neurochirurgica
N2  - Purpose
Anaemia is common in patients presenting with aneurysmal subarachnoid (aSAH) and intracerebral haemorrhage (ICH). In surgical patients, anaemia was identified as an idenpendent risk factor for postoperative mortality, prolonged hospital length of stay (LOS) and increased risk of red blood cell (RBC) transfusion. This multicentre cohort observation study describes the incidence and effects of preoperative anaemia in this critical patient collective for a 10-year period.

Methods
This multicentre observational study included adult in-hospital surgical patients diagnosed with aSAH or ICH of 21 German hospitals (discharged from 1 January 2010 to 30 September 2020). Descriptive, univariate and multivariate analyses were performed to investigate the incidence and association of preoperative anaemia with RBC transfusion, in-hospital mortality and postoperative complications in patients with aSAH and ICH.

Results
A total of n = 9081 patients were analysed (aSAH n = 5008; ICH n = 4073). Preoperative anaemia was present at 28.3% in aSAH and 40.9% in ICH. RBC transfusion rates were 29.9% in aSAH and 29.3% in ICH. Multivariate analysis revealed that preoperative anaemia is associated with a higher risk for RBC transfusion (OR = 3.25 in aSAH, OR = 4.16 in ICH, p < 0.001), for in-hospital mortality (OR = 1.48 in aSAH, OR = 1.53 in ICH, p < 0.001) and for several postoperative complications.

Conclusions
Preoperative anaemia is associated with increased RBC transfusion rates, in-hospital mortality and postoperative complications in patients with aSAH and ICH.
KW  - aneurysmal subarachnoid haemorrhage
KW  - intracerebral haemorrhage
KW  - anaemia
KW  - red blood cell transfusion
KW  - patient blood management
Y1  - 2022
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-346754
VL  - 164
ER  -