TY  - JOUR
A1  - Riehl, R.
A1  - Schartl, Manfred
A1  - Kollinger, G.
T1  - Comparative studies on the ultrastructure of malignant melanoma in fish and human by freeze-etching and transmission electron microscopy
N2  - Malignant melanomas (MM) in the fish Xiphophorus and in humans were studied both by transmission electron microscopy (TEM) and freeze-etching (FE). In both fish and human melanomas the cells show interdigitations of the,plasma membranes. The nuclei are large and lobulated and have many nuclear pores. Melanosomes are abundant and melanosome complexes ("compound melanosomes") occur regularly. Pinocytotic vesicles could be demonstrated in fish and human melanomas showing iocal differences in frequency and distribution patterns in the tumor. lntercellular junctions are lacking in MM cells from fish and humans. The FE technique showed considerable advantages in demonstrating membrane-surface peculiarities such as nuclear pores or pinocytotic vesicles. The FE replicas of fish melanomas are like those of humans. These findings may support the hypothesis that melanoma in fish and humans reflect the same biological phenomenon.
KW  - Physiologische Chemie
KW  - Malignant melanoma
KW  - Fish
KW  - Human
KW  - Freeze-etching
KW  - Transmission electron microscopy
Y1  - 1984
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-61920
ER  - 
TY  - JOUR
A1  - Riehl, R.
A1  - Schartl, Manfred
T1  - A Transmission Electron Microscopical and Freeze-Etch Study of Malignant-Melanoma in Fish
N2  - No abstract available
KW  - Physiologische Chemie
Y1  - 1984
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-61916
ER  - 
TY  - JOUR
A1  - Schartl, Manfred
A1  - Barnekow, A.
T1  - Cellular src gene product detected in the freshwater sponge Spongilla lacustris
N2  - No abstract available
KW  - Physiologische Chemie
Y1  - 1984
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-61904
ER  - 
TY  - JOUR
A1  - Schartl, Manfred
A1  - Barnekow, A.
T1  - Differential expression of the cellular src gene during vertebrate development
N2  - No abstract available
KW  - Physiologische Chemie
Y1  - 1984
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-61893
ER  - 
TY  - JOUR
A1  - Schartl, Manfred
A1  - Schmidt, C. R.
A1  - Anders, A.
A1  - Barnekow, A.
T1  - Elevated expression of the cellular src gene in tumors of differing etiologies in Xiphophorus
N2  - No abstract available
KW  - Physiologische Chemie
Y1  - 1985
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-61889
ER  - 
TY  - JOUR
A1  - Barnekow, A.
A1  - Paul, E.
A1  - Schartl, Manfred
T1  - Expression of the c-src protooncogene in human skin tumors
N2  - No abstract available
KW  - Physiologische Chemie
Y1  - 1987
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-61870
ER  - 
TY  - JOUR
A1  - Barnekow, A.
A1  - Schartl, Manfred
T1  - Comparative studies on the src proto-oncogene and its gene product pp60\(^{c-src}\) in normal and neoplastic tissues of lower vertebrates
N2  - No abstract available
KW  - Physiologische Chemie
Y1  - 1987
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-61869
ER  - 
TY  - JOUR
A1  - Maueler, W.
A1  - Eigenbrodt, E.
A1  - Schartl, Manfred
T1  - Intermediary metabolism of normal and tumorous tissue of Xiphophorus (Teleostei: Poeciliidae)
N2  - No abstract available
KW  - Physiologische Chemie
Y1  - 1987
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-61855
ER  - 
TY  - JOUR
A1  - Schartl, Manfred
T1  - A sex chromosomal restriction-fragment-length marker linked to melanoma-determining Tu loci in Xiphophorus
N2  - No abstract available
KW  - Physiologische Chemie
Y1  - 1988
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-61842
ER  - 
TY  - JOUR
A1  - Schartl, Manfred
A1  - Peter, R. U.
T1  - Progressive growth of fish tumors after transplantation into thymus-aplastic (nu/nu) mice
N2  - No abstract available
KW  - Physiologische Chemie
Y1  - 1988
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-61833
ER  -