TY  - CHAP
A1  - Fiala, Brigitte
A1  - Maschwitz, Ulrich
A1  - Tho, Yow Pong
T1  - The association between Macaranga trees and ants in South-east Asia
N2  - No abstract available
KW  - Macaranga
Y1  - 1991
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-54752
ER  - 
TY  - CHAP
A1  - Gotz, R.
A1  - Schartl, Manfred
T1  - The conservation of neurotrophic factors during vertebrate evolution
N2  - No abstract available
KW  - Physiologische Chemie
Y1  - 1994
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-61964
ER  - 
TY  - CHAP
A1  - Fiala, Brigitte
A1  - Federle, W.
A1  - Maschwitz, U.
A1  - Azarae, Idris
T1  - The first myrmecophytic 2-partner-system in the genus Macaranga: The association between Macaranga puncticulata and a Componotus (Colobopsis) in Malaysia
N2  - No abstract available
KW  - Biologie
Y1  - 1994
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-55144
ER  - 
TY  - CHAP
A1  - Scheer, Ulrich
A1  - Franke, Werner W.
T1  - Transcriptional complexes of  nucleolar genes
N2  - No abstract available
Y1  - 1976
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-41072
ER  - 
TY  - CHAP
A1  - Trendelenburg, M. F.
A1  - Franke, Werner W.
A1  - Spring, H.
A1  - Scheer, Ulrich
T1  - Ultrastructure of transcription in the nucleoli of the green algae Acetabularia major and A. mediterranea
N2  - No abstract available
Y1  - 1975
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-33779
ER  - 
TY  - CHAP
A1  - Anders, Fritz
A1  - Schartl, Manfred
A1  - Barnekow, Angelika
T1  - Xiphophorus as an in vivo model for studies on oncogenes
N2  - The capacity of Xiphophorus to develop neoplasia can be formally assigned to a "tumor gene" (Tu), which appears to be a normal part of the genome of all individuals. The wild fish have evolved population-specific and cell type-specific systems of regulatory genes (R) for Tu that protect the fish from neoplasia. Hybridization of members of different wild populations in the laborstory followed by treatment of the hybrids with carcinogens led to disintegration of the R systems permitting excessive expression of Tu and thus resulting in neoplasia. Certain hybrids developed neoplasia even spontaneously. Observations on the genuine phenotypic effect of the derepressed Tu in the early embryo indicated an essential normal function of this oncogene in cell differentiation, proliferation and cell-cell communication. Tu appeared to be indispensable in the genome but may also be present in accessory copics. Recently, c-src, the cellular homolog of the Rous sarcoma virus oncogene v-src, was detected in Xiphophorus. The protein product of c-src, pp60c-src, was identified and then examined by its associated kinase activity. This pp60c-src was found in all individuals tested, but, depending on the genotype, its kinase activity was different. The genetic characters of c-src, such as linkage relations, dosage relations, expression, etc., correspond to those of Tu. From a systematic study which showed that pp60c-src was present in all metazoa tested ranging from mammals down to sponges, we concluded that c-src has evolved with the multicellular organization of animals. Neoplasia of animals and humans is a characteristic closely related to this evolution. Our data showed that small aquariurn fish, besides being used successfully because they are time-, space-, and money-saving systems for carcinogenicity testing, are also highly suitable for basic studies on neoplasia at the populational, morphological, developmental, cell biological, and molecular levels.
KW  - Schwertkärpfling
KW  - In vivo
KW  - Onkogen
Y1  - 1984
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-86398
ER  -