TY  - JOUR
A1  - Tacke, Reinhold
A1  - Linoh, Haryanto
A1  - Stumpf, Burghard
A1  - Abraham, Wolf-Rainer
A1  - Kieslich, Klaus
A1  - Ernst, Ludger
T1  - Mikrobiologische Umwandlung von Silicium-Verbindungen: Enantioselektive Reduktion von Acetessigsäure-(trimethylsilylalkyl)estern und deren Carba-Analoga
T1  - Microbiological Transformation of Silicon Compounds: Enantioselective Reduction of Trimethylsilylalkyl Acetoacetates and their Carba-Analogues
JF  - Zeitschrift für Naturforschung B
N2  - The trimethylsilylalkyl acetoacetates 1 b and 2 b as well as their carba analogues 1 a and 2 a have been reduced microbiologically by Kloeckera corticis (ATCC 20109), leading to the corresponding ( + )-3(S)-hydroxybutanoates 3b, 4b, 3a, and 4a. The enantiomeric purity was found to be 80% (3a, 3b, 4b) and 65% (4a), respectively. The reduction of lb and 2b is - to our knowledge - the first example for a controlled microbiological transformation of organosilicon substrates.
KW  - enantioselective reduction
KW  - microbiological transformation
KW  - silicon compounds
Y1  - 1983
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-128304
VL  - 38
IS  - 5
ER  -