TY  - JOUR
A1  - Flügel, Rolf M.
A1  - Maurer, Bernd
A1  - Bannert, Helmut
A1  - Rethwilm, Axel
A1  - Schnitzler, Paul
A1  - Darai, Gholamreza
T1  - Nucleotide sequence analysis of a cloned DNA fragment from human cells reveals homology to retrotransposons
N2  - During molecular cloning of proviral DNA of human. spumaretroVirus, various recombinant clones were estabUshed and analyzed. Blot hybridization revealed that one of the recoinbinant plasmids bad the characteristic features of a member of the long interspersed repetitive sequences famlly. The DNA element was analyzed by restrictioil mapping and nuelootide sequencing. It showed a high degree of amino acid sequence homology of 54.3% when conipared with the 5'-terminal part of the pol gelie product of the murine retrotransposon LIMd. The 3' region of the cloned DNA element encodes proteins witb an even higher degree of homology of 67.4% in comparison to the corresponding parts of a member of the primate Kpnl sequence family.
KW  - Virologie
Y1  - 1987
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-61525
ER  -