TY  - JOUR
A1  - Petritsch, Bernhard
A1  - Köstler, Herbert
A1  - Gassenmaier, Tobias
A1  - Kunz, Andreas S
A1  - Bley, Thorsten A
A1  - Horn, Michael
T1  - An investigation into potential gender-specific differences in myocardial triglyceride content assessed by \(^{1}\)H-Magnetic Resonance Spectroscopy at 3Tesla
JF  - Journal of International Medical Research
N2  - Objective:
Over the past decade, myocardial triglyceride content has become an accepted biomarker for chronic metabolic and cardiac disease. The purpose of this study was to use proton (hydrogen 1)-magnetic resonance spectroscopy (\(^{1}\)H-MRS) at 3Tesla (3 T) field strength to assess potential gender-related differences in myocardial triglyceride content in healthy individuals.

Methods:
Cardiac MR imaging was performed to enable accurate voxel placement and obtain functional and morphological information. Double triggered (i.e., ECG and respiratory motion gating) \(^{1}\)H-MRS was used to quantify myocardial triglyceride levels for each gender. Two-sample t-test and Mann-Whitney U-test were used for statistical analyses.

Results:
In total, 40 healthy volunteers (22 male, 18 female; aged >18 years and age matched) were included in the study. Median myocardial triglyceride content was 0.28% (interquartile range [IQR] 0.17–0.42%) in male and 0.24% (IQR 0.14–0.45%) in female participants, and no statistically significant difference was observed between the genders. Furthermore, no gender-specific difference in ejection fraction was observed, although on average, male participants presented with a higher mean ± SD left ventricular mass (136.3 ± 25.2 g) than female participants (103.9 ± 16.1 g).

Conclusions:
The study showed that \(^{1}\)H-MRS is a capable, noninvasive tool for acquisition of myocardial triglyceride metabolites. Myocardial triglyceride concentration was shown to be unrelated to gender in this group of healthy volunteers.
KW  - cardiac
KW  - magnetic resonance imaging
KW  - 1H-Magnetic resonance spectroscopy (1H-MRS)
KW  - myocardium
KW  - triglycerides
KW  - metabolism
KW  - gender
Y1  - 2016
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-168808
VL  - 44
IS  - 3
ER  - 
TY  - JOUR
A1  - Sauer, Stephanie
A1  - Goltz, Jan P.
A1  - Gassenmaier, Tobias
A1  - Kunz, Andreas S.
A1  - Bley, Thorsten A.
A1  - Klein, Detlef
A1  - Petritsch, Bernhard
T1  - Partial Segmental Thrombosis of the Corpus Cavernosum (PSTCC) diagnosed by contrast-enhanced ultrasound: a case report
JF  - BMC Urology
N2  - Background
Partial segmental thrombosis of the corpus cavernosum (PSTCC) is a rare disease predominantly occurring in young men. Cardinal symptoms are pain and perineal swelling. Although several risk factors are described in the literature, the exact etiology of penile thrombosis remains unclear in most cases. MRI or ultrasound (US) is usually used for diagnosing this condition.

Case presentation
We report a case of penile thrombosis after left-sided varicocele ligature in a young patient. The diagnosis was established using contrast-enhanced ultrasound (CEUS) and was confirmed by contrast-enhanced magnetic resonance imaging (ceMRI). Successful conservative treatment consisted of systemic anticoagulation using low molecular weight heparin and acetylsalicylic acid.

Conclusion
PSTCC is a rare condition in young men and appears with massive pain and perineal swelling. In case of suspected PSTCC utilization of CEUS may be of diagnostic benefit.
KW  - MRI
KW  - priapism
KW  - corpus cavernosum
KW  - penile thrombosis
KW  - contrast-enhanced ultrasound
Y1  - 2014
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-126495
VL  - 14
IS  - 100
ER  -