TY - JOUR A1 - Gessler, Manfred A1 - Grupe, Andrew A1 - Grzeschik, Karl-Heinz A1 - Pongs, Olaf T1 - The potassium channel gene HK1 maps to human chromosome 11p14.1, close to the FSHB gene N2 - Transiently activating (A-type) potassium (K) channels are important regulators of action potential and action potential firing frequencies. HK1 designates the firsthuman cDNA that is highly homologous to the rat RCK4 cDNA that codes for an A-type K-channel. The HK1 channel is expressed in heart. By somatic cell hybrid analysis, the HK1 gene has been assigned to human chromosome 11p13-pl4, the WAGR deletion region (Wilms tumor, aniridia, genito-urinary abnormalities and mental retardation). Subsequent pulsed field gel (PFG) analysis and comparison with the well-established PFG map of this region localized the gene to 11p14, 200-600 kb telomeric to the FSHB gene. KW - Biochemie Y1 - 1992 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-59184 ER - TY - JOUR A1 - Wolf, Markus A1 - Klug, Jörg A1 - Hackenberg, Reinhard A1 - Gessler, Manfred A1 - Grzeschik, Karl-Heinz A1 - Beato, Miguel A1 - Suske, Guntram T1 - Human CC10, the homologue of rabbit uteroglobin: genomic cloning, chromosomal localization and expression in endometrial cell lines N2 - No abstract available KW - Biochemie Y1 - 1992 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-59206 ER - TY - JOUR A1 - Vortkamp, Andrea A1 - Franz, Thomas A1 - Gessler, Manfred A1 - Grzeschik, Karl-Heinz T1 - Deletion of GLI3 supports the homology of the human Greig cephalopolysyndactyly syndrome (GCPS) and the mouse mutant extra toes (Xt) N2 - No abstract available Y1 - 1992 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-30166 ER -