TY - CHAP A1 - Heusermann, U. A1 - Nöthling, R. A1 - Hansmann, M. L. A1 - Ulrichs, Karin T1 - Immunhistochemische und immunelektronenmikroskopischeUntersuchungen zum Vorkommen von dendritischen Zellen im Pankreas der Ratte T1 - Immunohistochemical and immune electron microscopy studies of the occurrence of dendritic cells in the pancreas of the rat N2 - Dendritic cells, first described by STEINMAN and COHN in the mouse spleen and now called lymphoid dendritic cells (LDC), were investigated in the rat pancreas with the monoclonal antibodies 29AI-L. T. and MRC-OX17, which both recognize the la-antigen immunohistochemically and immune electron microscopically. la-positive cells with a dendritic morphology were found in the connective tissue of the cxocrine and endocrine pancreas. Immune e1ectron microscopically, the Ia-antibodies were 10- calized on the cell surface and in sm all vesicles. A small portion of the la-positive cells showed additional acid phosphatase positivity, i. e. were la-positive macrophages. The other la-positive cells were probably LDC, which may be important in the elimination of foreign antigens, e. g. bacteria and vIruses. Y1 - 1987 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-45689 ER -