TY  - JOUR
A1  - Werner, Rudolf A.
A1  - Ordonez, Alvaro A.
A1  - Sanchez-Bautista, Julian
A1  - Marcus, Charles
A1  - Lapa, Constantin
A1  - Rowe, Steven P.
A1  - Pomper, Martin G.
A1  - Leal, Jeffrey P.
A1  - Lodge, Martin A.
A1  - Javadi, Mehrbod S.
A1  - Jain, Sanjay K.
A1  - Higuchi, Takahiro
T1  - Novel functional renal PET imaging with 18F-FDS in human subjects
JF  - Clinical Nuclear Medicine
N2  - The novel PET probe 2-deoxy-2-18F-fluoro-D-sorbitol (18F-FDS) has demonstrated favorable renal kinetics in animals. We aimed to elucidate its imaging properties in two human volunteers. 18F-FDS was produced by a simple one-step reduction from 18F-FDG. On dynamic renal PET, the cortex was delineated and activity gradually transited in the parenchyma, followed by radiotracer excretion. No adverse effects were reported. Given the higher spatiotemporal resolution of PET relative to conventional scintigraphy, 18F-FDS PET offers a more thorough evaluation of human renal kinetics. Due to its simple production from 18F-FDG, 18F-FDS is virtually available at any PET facility with radiochemistry infrastructure.
KW  - 2-deoxy-2-18F-fluoro-D-sorbitol
KW  - Positronen-Emissions-Tomografie
KW  - 18F-FDS
KW  - renal imaging
KW  - Positron-Emission Tomography
KW  - split renal function
KW  - kidney
Y1  - 2019
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-174634
SN  - 0363-9762
VL  - 44
IS  - 5
ER  - 
TY  - CHAP
A1  - Werner, Rudolf A.
A1  - Marcus, Charles
A1  - Sheikhbahaei, Sara
A1  - Higuchi, Takahiro
A1  - Solnes, Lilja B.
A1  - Rowe, Steven P.
A1  - Buck, Andreas K.
A1  - Lapa, Constantin
A1  - Javadi, Mehrbod S.
T1  - Diagnostic Accuracy of Visual Assessment of an Initial DaT-Scan in Comparison to a Fully Automatic Semiquantitative Method
T2  - Journal of Nuclear Medicine
N2  - No abstract available.
KW  - Parkinson-Krankheit
KW  - SPECT
KW  - Parkinson
KW  - Parkinson Disease
KW  - DaTscan
KW  - Ioflupane
KW  - molecular imaging
Y1  - 2018
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-162208
UR  - http://jnm.snmjournals.org/content/59/supplement_1/626.abstract
SN  - 0161-5505
N1  - This research was originally published in JNM. Rudolf A. Werner, Charles Marcus, Sara Sheikhbahaei, Takahiro Higuchi, Lilja B. Solnes, Steven P. Rowe, Andreas K. Buck, Constantin Lapa, Mehrbod S. Javadi. Diagnostic Accuracy of Visual Assessment of an Initial DaT-Scan in Comparison to a Fully Automatic Semiquantitative Method. J Nucl Med. May 1, 2018; vol. 59 no. supplement 1:626. © SNMMI.
VL  - 59
IS  - Supplement No. 1
SP  - 626
ER  - 
TY  - CHAP
A1  - Werner, Rudolf A.
A1  - Marcus, Charles
A1  - Sheikhbahaei, Sara
A1  - Higuchi, Takahiro
A1  - Solnes, Lilja B.
A1  - Rowe, Steven P.
A1  - Buck, Andreas K.
A1  - Lapa, Constantin
A1  - Javadi, Mehrbod S.
T1  - The Impact of Ageing on Dopamine Transporter Imaging
T2  - Journal of Nuclear Medicine
N2  - No abstract available.
KW  - Parkinson-Krankheit
KW  - Parkinson
KW  - Parkinson Disease
KW  - DaTscan
KW  - Ioflupane
KW  - SPECT
KW  - molecular imaging
KW  - ageing
Y1  - 2018
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-162213
UR  - http://jnm.snmjournals.org/content/59/supplement_1/1646.abstract
SN  - 0161-5505
N1  - This research was originally published in JNM. Rudolf A. Werner, Charles Marcus, Sara Sheikhbahaei, Takahiro Higuchi, Lilja B. Solnes, Steven P. Rowe, Andreas K. Buck, Constantin Lapa, Mehrbod S. Javadi. The Impact of Ageing on Dopamine Transporter Imaging. J Nucl Med. May 1, 2018; vol. 59 no. supplement 1:1646. © SNMMI.
VL  - 59
IS  - Supplement No 1
SP  - 1646
ER  -