TY  - JOUR
A1  - Riehl, R.
A1  - Schartl, Manfred
T1  - A Transmission Electron Microscopical and Freeze-Etch Study of Malignant-Melanoma in Fish
N2  - No abstract available
KW  - Physiologische Chemie
Y1  - 1984
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-61916
ER  - 
TY  - JOUR
A1  - Riehl, R.
A1  - Schartl, Manfred
A1  - Kollinger, G.
T1  - Comparative studies on the ultrastructure of malignant melanoma in fish and human by freeze-etching and transmission electron microscopy
N2  - Malignant melanomas (MM) in the fish Xiphophorus and in humans were studied both by transmission electron microscopy (TEM) and freeze-etching (FE). In both fish and human melanomas the cells show interdigitations of the,plasma membranes. The nuclei are large and lobulated and have many nuclear pores. Melanosomes are abundant and melanosome complexes ("compound melanosomes") occur regularly. Pinocytotic vesicles could be demonstrated in fish and human melanomas showing iocal differences in frequency and distribution patterns in the tumor. lntercellular junctions are lacking in MM cells from fish and humans. The FE technique showed considerable advantages in demonstrating membrane-surface peculiarities such as nuclear pores or pinocytotic vesicles. The FE replicas of fish melanomas are like those of humans. These findings may support the hypothesis that melanoma in fish and humans reflect the same biological phenomenon.
KW  - Physiologische Chemie
KW  - Malignant melanoma
KW  - Fish
KW  - Human
KW  - Freeze-etching
KW  - Transmission electron microscopy
Y1  - 1984
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-61920
ER  -