TY  - JOUR
A1  - Wan, Wei-Lin
A1  - Zhang, Lisha
A1  - Pruitt, Rory
A1  - Zaidem, Maricris
A1  - Brugman, Rik
A1  - Ma, Xiyu
A1  - Krol, Elzbieta
A1  - Perraki, Artemis
A1  - Kilian, Joachim
A1  - Grossmann, Guido
A1  - Stahl, Mark
A1  - Shan, Libo
A1  - Zipfel, Cyril
A1  - van Kan, Jan A. L.
A1  - Hedrich, Rainer
A1  - Weigel, Detlef
A1  - Gust, Andrea A.
A1  - Nürnberger, Thorsten
T1  - Comparing Arabidopsis receptor kinase and receptor protein-mediated immune signaling reveals BIK1-dependent differences
JF  - New Phytologist
N2  - Pattern recognition receptors (PRRs) sense microbial patterns and activate innate immunity against attempted microbial invasions. The leucine-rich repeat receptor kinases (LRR-RK) FLS2 and EFR, and the LRR receptor protein (LRR-RP) receptors RLP23 and RLP42, respectively, represent prototypical members of these two prominent and closely related PRR families.

We conducted a survey of Arabidopsis thaliana immune signaling mediated by these receptors to address the question of commonalities and differences between LRR-RK and LRR-RP signaling.

Quantitative differences in timing and amplitude were observed for several early immune responses, with RP-mediated responses typically being slower and more prolonged than those mediated by RKs. Activation of RLP23, but not FLS2, induced the production of camalexin. Transcriptomic analysis revealed that RLP23-regulated genes represent only a fraction of those genes differentially expressed upon FLS2 activation. Several positive and negative regulators of FLS2-signaling play similar roles in RLP23 signaling. Intriguingly, the cytoplasmic receptor kinase BIK1, a positive regulator of RK signaling, acts as a negative regulator of RP-type immune receptors in a manner dependent on BIK1 kinase activity.

Our study unveiled unexpected differences in two closely related receptor systems and reports a new negative role of BIK1 in plant immunity.
KW  - Arabidopsis
KW  - immune receptor
KW  - immune signaling comparison
KW  - plant immunity
KW  - receptor kinase
KW  - receptor protein
Y1  - 2019
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-233385
VL  - 221
ER  -