TY  - JOUR
A1  - Sendtner, Michael
A1  - Carroll, P.
A1  - Holtmann, B
A1  - Hughes, R. A.
A1  - Thoenen, H.
T1  - Ciliary Neurotrophic Factor
N2  - No abstract available
KW  - ciliary neuron
KW  - ciliary neurotrophic factor
KW  - motoneuron
KW  - nonneuronaI cells
KW  - homologous recombination
Y1  - 1994
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-42545
ER  - 
TY  - JOUR
A1  - Sendtner, Michael
A1  - Thoenen, Hans
A1  - Holtmann, B.
A1  - Kohlbeck, R.
A1  - Barde, Y.-A.
T1  - Brain-derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section
N2  - Motoneurons innervating the skeletal musculature were among the first neurons shown to require the presence of their target cells to develop appropriatelyl,2. But the characterization of molecules allowing motoneuron survival has been difficult. Ciliary neurotrophic factor prevents the death of motoneurons3-6, but its gene is not expressed during development7. Although the presence of a neurotrophin receptor on developing motoneurons8-1O has suggested a role for neurotrophins, none could be shown to promote motoneuron survival in vitro3. We report here that brainderived neurotrophic factor can prevent the death of axotomized motoneurons in newborn rats, suggesting a role for this neurotrophin for motoneuron survival in vivo.
Y1  - 1992
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-42673
ER  -