TY  - JOUR
A1  - Buder, Kristina
A1  - Müller, Philip A.
A1  - Beekmann, Gabriele
A1  - Ugurel, Selma
A1  - Bröcker, Eva-Bettina
A1  - Becker, Jürgen C.
T1  - Denileukin Diftitox plus Total Skin Electron Beam Radiation in Patients with Treatment-refractory Cutaneous T-cell Lymphoma (Mycosis Fungoides): Report of Four Cases
JF  - Acta Dermato-Venereologica
N2  - Mycosis fungoides (MF) is the most common cutaneous T-cell lymphoma (CTCL) (1). Most patients initially respond well to standard therapy, but advanced MF is often treatment refractory. Thus, a combination of the available treatment options is an important strategy. Total skin electron beam radiation (TSEB) is effective in MF, with a complete remission rate of up to 90% in the early stages. However, in patients with more advanced stages, remission rates are considerably lower (2, 3). Denileukin diftitox (DD) (Ontak®) is a recombinant fusion protein of the receptor-binding domain of interleukin (IL)-2 and the enzymatic and translocation domains of diphtheria toxin (4). It targets the alpha-subunit of the IL-2-receptor (CD25). There are no reports on this combination therapy in MF.
KW  - lymphoma
Y1  - 2014
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-120091
N1  - Der Zugang zum Volltext ist aus rechtlichen Gründen gesperrt.
VL  - 94
ER  - 
TY  - JOUR
A1  - Müller, Bettina
A1  - Richter, Tobias
A1  - Karageorgos, Panagiotis
A1  - Krawietz, Sabine
A1  - Ennemoser, Marco
T1  - Effects of a syllable-based reading intervention in poor-reading fourth graders
JF  - Frontiers in Psychology
N2  - In transparent orthographies, persistent reading fluency difficulties are a major cause of poor reading skills in primary school. The purpose of the present study was to investigate effects of a syllable-based reading intervention on word reading fluency and reading comprehension among German-speaking poor readers in Grade 4. The 16-session intervention was based on analyzing the syllabic structure of words to strengthen the mental representations of syllables and words that consist of these syllables. The training materials were designed using the 500 most frequent syllables typically read by fourth graders. The 75 poor readers were randomly allocated to the treatment or the control group. Results indicate a significant and strong effect on the fluency of recognizing single words, whereas text-level reading comprehension was not significantly improved by the training. The specific treatment effect provides evidence that a short syllable-based approach works even in older poor readers at the end of primary school.
KW  - word reading fluency
KW  - syllable-based intervention
KW  - older poor readers
KW  - primary school
KW  - reading comprehension
Y1  - 2017
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-158841
VL  - 8
IS  - 1635
ER  -