TY  - JOUR
A1  - Cataldi, Eleonora
A1  - Raschig, Martina
A1  - Gutmann, Marcus
A1  - Geppert, Patrick T.
A1  - Ruopp, Matthias
A1  - Schock, Marvin
A1  - Gerwe, Hubert
A1  - Bertermann, Rüdiger
A1  - Meinel, Lorenz
A1  - Finze, Maik
A1  - Nowak‐Król, Agnieszka
A1  - Decker, Michael
A1  - Lühmann, Tessa
T1  - Amber Light Control of Peptide Secondary Structure by a Perfluoroaromatic Azobenzene Photoswitch
JF  - ChemBioChem
N2  - The incorporation of photoswitches into the molecular structure of peptides and proteins enables their dynamic photocontrol in complex biological systems. Here, a perfluorinated azobenzene derivative triggered by amber light was site‐specifically conjugated to cysteines in a helical peptide by perfluoroarylation chemistry. In response to the photoisomerization (trans→cis) of the conjugated azobenzene with amber light, the secondary structure of the peptide was modulated from a disorganized into an amphiphilic helical structure.
KW  - amber light
KW  - decafluoroazobezene
KW  - peptide stapling
KW  - photocontrol
KW  - perfluoroarylation
Y1  - 2023
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-312480
VL  - 24
IS  - 5
ER  -