TY - CHAP A1 - Anders, F. A1 - Scholl, E. A1 - Schartl, Manfred T1 - Xiphophorus als Modell in der Krebsforschung N2 - No abstract available. KW - Schwertkärpfling KW - Krebsforschung KW - Modell Y1 - 1979 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-72752 ER - TY - JOUR A1 - Bousquet, J. A1 - Farrell, J. A1 - Crooks, G. A1 - Hellings, P. A1 - Bel, E. H. A1 - Bewick, M. A1 - Chavannes, N. H. A1 - Correia de Sousa, J. A1 - Cruz, A. A. A1 - Haahtela, T. A1 - Joos, G. A1 - Khaltaev, N. A1 - Malva, J. A1 - Muraro, A. A1 - Nogues, M. A1 - Palkonen, S. A1 - Pedersen, S. A1 - Robalo-Cordeiro, C. A1 - Samolinski, B. A1 - Strandberg, T. A1 - Valiulis, A. A1 - Yorgancioglu, A. A1 - Zuberbier, T. A1 - Bedbrook, A. A1 - Aberer, W. A1 - Adachi, M. A1 - Agusti, A. A1 - Akdis, C. A. A1 - Akdis, M. A1 - Ankri, J. A1 - Alonso, A. A1 - Annesi-Maesano, I. A1 - Ansotegui, I. J. A1 - Anto, J. M. A1 - Arnavielhe, S. A1 - Arshad, H. A1 - Bai, C. A1 - Baiardini, I. A1 - Bachert, C. A1 - Baigenzhin, A. K. A1 - Barbara, C. A1 - Bateman, E. D. A1 - Beghé, B. A1 - Ben Kheder, A. A1 - Bennoor, K. S. A1 - Benson, M. A1 - Bergmann, K. C. A1 - Bieber, T. A1 - Bindslev-Jensen, C. A1 - Bjermer, L. A1 - Blain, H. A1 - Blasi, F. A1 - Boner, A. L. A1 - Bonini, M. A1 - Bonini, S. A1 - Bosnic-Anticevitch, S. A1 - Boulet, L. P. A1 - Bourret, R. A1 - Bousquet, P. J. A1 - Braido, F. A1 - Briggs, A. H. A1 - Brightling, C. E. A1 - Brozek, J. A1 - Buhl, R. A1 - Burney, P. G. A1 - Bush, A. A1 - Caballero-Fonseca, F. A1 - Caimmi, D. A1 - Calderon, M. A. A1 - Calverley, P. M. A1 - Camargos, P. A. M. A1 - Canonica, G. W. A1 - Camuzat, T. A1 - Carlsen, K. H. A1 - Carr, W. A1 - Carriazo, A. A1 - Casale, T. A1 - Cepeda Sarabia, A. M. A1 - Chatzi, L. A1 - Chen, Y. Z. A1 - Chiron, R. A1 - Chkhartishvili, E. A1 - Chuchalin, A. G. A1 - Chung, K. F. A1 - Ciprandi, G. A1 - Cirule, I. A1 - Cox, L. A1 - Costa, D. J. A1 - Custovic, A. A1 - Dahl, R. A1 - Dahlen, S. E. A1 - Darsow, U. A1 - De Carlo, G. A1 - De Blay, F. A1 - Dedeu, T. A1 - Deleanu, D. A1 - De Manuel Keenoy, E. A1 - Demoly, P. A1 - Denburg, J. A. A1 - Devillier, P. A1 - Didier, A. A1 - Dinh-Xuan, A. T. A1 - Djukanovic, R. A1 - Dokic, D. A1 - Douagui, H. A1 - Dray, G. A1 - Dubakiene, R. A1 - Durham, S. R. A1 - Dykewicz, M. S. A1 - El-Gamal, Y. A1 - Emuzyte, R. A1 - Fabbri, L. M. A1 - Fletcher, M. A1 - Fiocchi, A. A1 - Fink Wagner, A. A1 - Fonseca, J. A1 - Fokkens, W. J. A1 - Forastiere, F. A1 - Frith, P. A1 - Gaga, M. A1 - Gamkrelidze, A. A1 - Garces, J. A1 - Garcia-Aymerich, J. A1 - Gemicioğlu, B. A1 - Gereda, J. E. A1 - González Diaz, S. A1 - Gotua, M. A1 - Grisle, I. A1 - Grouse, L. A1 - Gutter, Z. A1 - Guzmán, M. A. A1 - Heaney, L. G. A1 - Hellquist-Dahl, B. A1 - Henderson, D. A1 - Hendry, A. A1 - Heinrich, J. A1 - Heve, D. A1 - Horak, F. A1 - Hourihane, J. O’. B. A1 - Howarth, P. A1 - Humbert, M. A1 - Hyland, M. E. A1 - Illario, M. A1 - Ivancevich, J. C. A1 - Jardim, J. R. A1 - Jares, E. J. A1 - Jeandel, C. A1 - Jenkins, C. A1 - Johnston, S. L. A1 - Jonquet, O. A1 - Julge, K. A1 - Jung, K. S. A1 - Just, J. A1 - Kaidashev, I. A1 - Kaitov, M. R. A1 - Kalayci, O. A1 - Kalyoncu, A. F. A1 - Keil, T. A1 - Keith, P. K. A1 - Klimek, L. A1 - Koffi N’Goran, B. A1 - Kolek, V. A1 - Koppelman, G. H. A1 - Kowalski, M. L. A1 - Kull, I. A1 - Kuna, P. A1 - Kvedariene, V. A1 - Lambrecht, B. A1 - Lau, S. A1 - Larenas‑Linnemann, D. A1 - Laune, D. A1 - Le, L. T. T. A1 - Lieberman, P. A1 - Lipworth, B. A1 - Li, J. A1 - Lodrup Carlsen, K. A1 - Louis, R. A1 - MacNee, W. A1 - Magard, Y. A1 - Magnan, A. A1 - Mahboub, B. A1 - Mair, A. A1 - Majer, I. A1 - Makela, M. J. A1 - Manning, P. A1 - Mara, S. A1 - Marshall, G. D. A1 - Masjedi, M. R. A1 - Matignon, P. A1 - Maurer, M. A1 - Mavale‑Manuel, S. A1 - Melén, E. A1 - Melo‑Gomes, E. A1 - Meltzer, E. O. A1 - Menzies‑Gow, A. A1 - Merk, H. A1 - Michel, J. P. A1 - Miculinic, N. A1 - Mihaltan, F. A1 - Milenkovic, B. A1 - Mohammad, G. M. Y. A1 - Molimard, M. A1 - Momas, I. A1 - Montilla‑Santana, A. A1 - Morais‑Almeida, M. A1 - Morgan, M. A1 - Mösges, R. A1 - Mullol, J. A1 - Nafti, S. A1 - Namazova‑Baranova, L. A1 - Naclerio, R. A1 - Neou, A. A1 - Neffen, H. A1 - Nekam, K. A1 - Niggemann, B. A1 - Ninot, G. A1 - Nyembue, T. D. A1 - O’Hehir, R. E. A1 - Ohta, K. A1 - Okamoto, Y. A1 - Okubo, K. A1 - Ouedraogo, S. A1 - Paggiaro, P. A1 - Pali‑Schöll, I. A1 - Panzner, P. A1 - Papadopoulos, N. A1 - Papi, A. A1 - Park, H. S. A1 - Passalacqua, G. A1 - Pavord, I. A1 - Pawankar, R. A1 - Pengelly, R. A1 - Pfaar, O. A1 - Picard, R. A1 - Pigearias, B. A1 - Pin, I. A1 - Plavec, D. A1 - Poethig, D. A1 - Pohl, W. A1 - Popov, T. A. A1 - Portejoie, F. A1 - Potter, P. A1 - Postma, D. A1 - Price, D. A1 - Rabe, K. F. A1 - Raciborski, F. A1 - Radier Pontal, F. A1 - Repka‑Ramirez, S. A1 - Reitamo, S. A1 - Rennard, S. A1 - Rodenas, F. A1 - Roberts, J. A1 - Roca, J. A1 - Rodriguez Mañas, L. A1 - et al, T1 - Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5) JF - Clinical and Translational Allergy N2 - Action Plan B3 of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) focuses on the integrated care of chronic diseases. Area 5 (Care Pathways) was initiated using chronic respiratory diseases as a model. The chronic respiratory disease action plan includes (1) AIRWAYS integrated care pathways (ICPs), (2) the joint initiative between the Reference site MACVIA-LR (Contre les MAladies Chroniques pour un VIeillissement Actif) and ARIA (Allergic Rhinitis and its Impact on Asthma), (3) Commitments for Action to the European Innovation Partnership on Active and Healthy Ageing and the AIRWAYS ICPs network. It is deployed in collaboration with the World Health Organization Global Alliance against Chronic Respiratory Diseases (GARD). The European Innovation Partnership on Active and Healthy Ageing has proposed a 5-step framework for developing an individual scaling up strategy: (1) what to scale up: (1-a) databases of good practices, (1-b) assessment of viability of the scaling up of good practices, (1-c) classification of good practices for local replication and (2) how to scale up: (2-a) facilitating partnerships for scaling up, (2-b) implementation of key success factors and lessons learnt, including emerging technologies for individualised and predictive medicine. This strategy has already been applied to the chronic respiratory disease action plan of the European Innovation Partnership on Active and Healthy Ageing. KW - EIP on AHA KW - European Innovation Partnership on Active and Healthy Ageing KW - AIRWAYS ICPs KW - MACVIA KW - Scaling up KW - Chronic respiratory diseases KW - ARIA Y1 - 2016 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-166874 VL - 6 IS - 29 ER - TY - JOUR A1 - Eckardt, Jan-Niklas A1 - Stasik, Sebastian A1 - Kramer, Michael A1 - Röllig, Christoph A1 - Krämer, Alwin A1 - Scholl, Sebastian A1 - Hochhaus, Andreas A1 - Crysandt, Martina A1 - Brümmendorf, Tim H. A1 - Naumann, Ralph A1 - Steffen, Björn A1 - Kunzmann, Volker A1 - Einsele, Hermann A1 - Schaich, Markus A1 - Burchert, Andreas A1 - Neubauer, Andreas A1 - Schäfer-Eckart, Kerstin A1 - Schliemann, Christoph A1 - Krause, Stefan W. A1 - Herbst, Regina A1 - Hänel, Mathias A1 - Frickhofen, Norbert A1 - Noppeney, Richard A1 - Kaiser, Ulrich A1 - Baldus, Claudia D. A1 - Kaufmann, Martin A1 - Rácil, Zdenek A1 - Platzbecker, Uwe A1 - Berdel, Wolfgang E. A1 - Mayer, Jiří A1 - Serve, Hubert A1 - Müller-Tidow, Carsten A1 - Ehninger, Gerhard A1 - Stölzel, Friedrich A1 - Kroschinsky, Frank A1 - Schetelig, Johannes A1 - Bornhäuser, Martin A1 - Thiede, Christian A1 - Middeke, Jan Moritz T1 - Loss-of-function mutations of BCOR are an independent marker of adverse outcomes in intensively treated patients with acute myeloid leukemia JF - Cancers N2 - Acute myeloid leukemia (AML) is characterized by recurrent genetic events. The BCL6 corepressor (BCOR) and its homolog, the BCL6 corepressor-like 1 (BCORL1), have been reported to be rare but recurrent mutations in AML. Previously, smaller studies have reported conflicting results regarding impacts on outcomes. Here, we retrospectively analyzed a large cohort of 1529 patients with newly diagnosed and intensively treated AML. BCOR and BCORL1 mutations were found in 71 (4.6%) and 53 patients (3.5%), respectively. Frequently co-mutated genes were DNTM3A, TET2 and RUNX1. Mutated BCORL1 and loss-of-function mutations of BCOR were significantly more common in the ELN2017 intermediate-risk group. Patients harboring loss-of-function mutations of BCOR had a significantly reduced median event-free survival (HR = 1.464 (95%-Confidence Interval (CI): 1.005–2.134), p = 0.047), relapse-free survival (HR = 1.904 (95%-CI: 1.163–3.117), p = 0.01), and trend for reduced overall survival (HR = 1.495 (95%-CI: 0.990–2.258), p = 0.056) in multivariable analysis. Our study establishes a novel role for loss-of-function mutations of BCOR regarding risk stratification in AML, which may influence treatment allocation. KW - acute myeloid leukemia KW - BCOR KW - BCORL1 KW - loss-of-function KW - risk stratification KW - survival Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-236735 SN - 2072-6694 VL - 13 IS - 9 ER - TY - CHAP A1 - Anders, F. A1 - Schartl, Manfred A1 - Scholl, E. T1 - Evaluation of environmental and hereditary factors in carcinogenesis, based on studies in Xiphophorus N2 - Neoplasia in Xiphophorus can be classified into a) a large group that is triggered by carcinogens; b) a large group triggered by promoters; c) a small group that develops "spontaneously" following interpopulational and interracial hybridizations; and d) a small group that develops "spontaneously" following germ line mutation. The process leading to susceptibility for neoplasia is represented by the disintegration of gene systems that normally protect the fish from neoplasia. Hybridization is the most effective process that leads to disintegration of the protection gene systems. Environmental factors may complete disintegration and thus may trigger neoplasia. It is discussed whether the findings on Xiphophorus may also apply to humans. KW - Schwertkärpfling KW - Gen KW - Umweltfaktor KW - Carcinogenese Y1 - 1981 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-72741 ER - TY - CHAP A1 - Anders, F. A1 - Scholl, E. A1 - Schartl, Manfred T1 - Environmental and hereditary factors in the causation of neoplasia, based on studies of the Xiphophorus fish melanoma system N2 - Neoplasia in Xiphophorus can be classified into: a) a Jarge group triggered by carcinogens; b) a large group triggered by promoters; and c) a small group that develops "spontaneously" according to Mendelian Jaw. The process leading to susceptibility for neoplasia is represented by the disintegration of gene systems that normally protect the fish from neoplasia. Interpopulational arid interracial hybridization is the most effective process that Ieads to disintegration of the protective gene systems. Environmental factors may complete disintegration in somatic cells and thus may trigger neoplasia. The applications of the findings on Xiphophorus to humans are discussed. KW - Schwertkärpfling KW - Gen KW - Umweltfaktor KW - Tumor Y1 - 1981 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-86402 ER - TY - JOUR A1 - Bousquet, Jean A1 - Anto, Josep M. A1 - Bachert, Claus A1 - Haahtela, Tari A1 - Zuberbier, Torsten A1 - Czarlewski, Wienczyslawa A1 - Bedbrook, Anna A1 - Bosnic‐Anticevich, Sinthia A1 - Walter Canonica, G. A1 - Cardona, Victoria A1 - Costa, Elisio A1 - Cruz, Alvaro A. A1 - Erhola, Marina A1 - Fokkens, Wytske J. A1 - Fonseca, Joao A. A1 - Illario, Maddalena A1 - Ivancevich, Juan‐Carlos A1 - Jutel, Marek A1 - Klimek, Ludger A1 - Kuna, Piotr A1 - Kvedariene, Violeta A1 - Le, LTT A1 - Larenas‐Linnemann, Désirée E. A1 - Laune, Daniel A1 - Lourenço, Olga M. A1 - Melén, Erik A1 - Mullol, Joaquim A1 - Niedoszytko, Marek A1 - Odemyr, Mikaëla A1 - Okamoto, Yoshitaka A1 - Papadopoulos, Nikos G. A1 - Patella, Vincenzo A1 - Pfaar, Oliver A1 - Pham‐Thi, Nhân A1 - Rolland, Christine A1 - Samolinski, Boleslaw A1 - Sheikh, Aziz A1 - Sofiev, Mikhail A1 - Suppli Ulrik, Charlotte A1 - Todo‐Bom, Ana A1 - Tomazic, Peter‐Valentin A1 - Toppila‐Salmi, Sanna A1 - Tsiligianni, Ioanna A1 - Valiulis, Arunas A1 - Valovirta, Erkka A1 - Ventura, Maria‐Teresa A1 - Walker, Samantha A1 - Williams, Sian A1 - Yorgancioglu, Arzu A1 - Agache, Ioana A1 - Akdis, Cezmi A. A1 - Almeida, Rute A1 - Ansotegui, Ignacio J. A1 - Annesi‐Maesano, Isabella A1 - Arnavielhe, Sylvie A1 - Basagaña, Xavier A1 - D. Bateman, Eric A1 - Bédard, Annabelle A1 - Bedolla‐Barajas, Martin A1 - Becker, Sven A1 - Bennoor, Kazi S. A1 - Benveniste, Samuel A1 - Bergmann, Karl C. A1 - Bewick, Michael A1 - Bialek, Slawomir A1 - E. Billo, Nils A1 - Bindslev‐Jensen, Carsten A1 - Bjermer, Leif A1 - Blain, Hubert A1 - Bonini, Matteo A1 - Bonniaud, Philippe A1 - Bosse, Isabelle A1 - Bouchard, Jacques A1 - Boulet, Louis‐Philippe A1 - Bourret, Rodolphe A1 - Boussery, Koen A1 - Braido, Fluvio A1 - Briedis, Vitalis A1 - Briggs, Andrew A1 - Brightling, Christopher E. A1 - Brozek, Jan A1 - Brusselle, Guy A1 - Brussino, Luisa A1 - Buhl, Roland A1 - Buonaiuto, Roland A1 - Calderon, Moises A. A1 - Camargos, Paulo A1 - Camuzat, Thierry A1 - Caraballo, Luis A1 - Carriazo, Ana‐Maria A1 - Carr, Warner A1 - Cartier, Christine A1 - Casale, Thomas A1 - Cecchi, Lorenzo A1 - Cepeda Sarabia, Alfonso M. A1 - H. Chavannes, Niels A1 - Chkhartishvili, Ekaterine A1 - Chu, Derek K. A1 - Cingi, Cemal A1 - Correia de Sousa, Jaime A1 - Costa, David J. A1 - Courbis, Anne‐Lise A1 - Custovic, Adnan A1 - Cvetkosvki, Biljana A1 - D'Amato, Gennaro A1 - da Silva, Jane A1 - Dantas, Carina A1 - Dokic, Dejan A1 - Dauvilliers, Yves A1 - De Feo, Giulia A1 - De Vries, Govert A1 - Devillier, Philippe A1 - Di Capua, Stefania A1 - Dray, Gerard A1 - Dubakiene, Ruta A1 - Durham, Stephen R. A1 - Dykewicz, Mark A1 - Ebisawa, Motohiro A1 - Gaga, Mina A1 - El‐Gamal, Yehia A1 - Heffler, Enrico A1 - Emuzyte, Regina A1 - Farrell, John A1 - Fauquert, Jean‐Luc A1 - Fiocchi, Alessandro A1 - Fink‐Wagner, Antje A1 - Fontaine, Jean‐François A1 - Fuentes Perez, José M. A1 - Gemicioğlu, Bilun A1 - Gamkrelidze, Amiran A1 - Garcia‐Aymerich, Judith A1 - Gevaert, Philippe A1 - Gomez, René Maximiliano A1 - González Diaz, Sandra A1 - Gotua, Maia A1 - Guldemond, Nick A. A1 - Guzmán, Maria‐Antonieta A1 - Hajjam, Jawad A1 - Huerta Villalobos, Yunuen R. A1 - Humbert, Marc A1 - Iaccarino, Guido A1 - Ierodiakonou, Despo A1 - Iinuma, Tomohisa A1 - Jassem, Ewa A1 - Joos, Guy A1 - Jung, Ki‐Suck A1 - Kaidashev, Igor A1 - Kalayci, Omer A1 - Kardas, Przemyslaw A1 - Keil, Thomas A1 - Khaitov, Musa A1 - Khaltaev, Nikolai A1 - Kleine‐Tebbe, Jorg A1 - Kouznetsov, Rostislav A1 - Kowalski, Marek L. A1 - Kritikos, Vicky A1 - Kull, Inger A1 - La Grutta, Stefania A1 - Leonardini, Lisa A1 - Ljungberg, Henrik A1 - Lieberman, Philip A1 - Lipworth, Brian A1 - Lodrup Carlsen, Karin C. A1 - Lopes‐Pereira, Catarina A1 - Loureiro, Claudia C. A1 - Louis, Renaud A1 - Mair, Alpana A1 - Mahboub, Bassam A1 - Makris, Michaël A1 - Malva, Joao A1 - Manning, Patrick A1 - Marshall, Gailen D. A1 - Masjedi, Mohamed R. A1 - Maspero, Jorge F. A1 - Carreiro‐Martins, Pedro A1 - Makela, Mika A1 - Mathieu‐Dupas, Eve A1 - Maurer, Marcus A1 - De Manuel Keenoy, Esteban A1 - Melo‐Gomes, Elisabete A1 - Meltzer, Eli O. A1 - Menditto, Enrica A1 - Mercier, Jacques A1 - Micheli, Yann A1 - Miculinic, Neven A1 - Mihaltan, Florin A1 - Milenkovic, Branislava A1 - Mitsias, Dimitirios I. A1 - Moda, Giuliana A1 - Mogica‐Martinez, Maria‐Dolores A1 - Mohammad, Yousser A1 - Montefort, Steve A1 - Monti, Ricardo A1 - Morais‐Almeida, Mario A1 - Mösges, Ralph A1 - Münter, Lars A1 - Muraro, Antonella A1 - Murray, Ruth A1 - Naclerio, Robert A1 - Napoli, Luigi A1 - Namazova‐Baranova, Leyla A1 - Neffen, Hugo A1 - Nekam, Kristoff A1 - Neou, Angelo A1 - Nordlund, Björn A1 - Novellino, Ettore A1 - Nyembue, Dieudonné A1 - O'Hehir, Robyn A1 - Ohta, Ken A1 - Okubo, Kimi A1 - Onorato, Gabrielle L. A1 - Orlando, Valentina A1 - Ouedraogo, Solange A1 - Palamarchuk, Julia A1 - Pali‐Schöll, Isabella A1 - Panzner, Peter A1 - Park, Hae‐Sim A1 - Passalacqua, Gianni A1 - Pépin, Jean‐Louis A1 - Paulino, Ema A1 - Pawankar, Ruby A1 - Phillips, Jim A1 - Picard, Robert A1 - Pinnock, Hilary A1 - Plavec, Davor A1 - Popov, Todor A. A1 - Portejoie, Fabienne A1 - Price, David A1 - Prokopakis, Emmanuel P. A1 - Psarros, Fotis A1 - Pugin, Benoit A1 - Puggioni, Francesca A1 - Quinones‐Delgado, Pablo A1 - Raciborski, Filip A1 - Rajabian‐Söderlund, Rojin A1 - Regateiro, Frederico S. A1 - Reitsma, Sietze A1 - Rivero‐Yeverino, Daniela A1 - Roberts, Graham A1 - Roche, Nicolas A1 - Rodriguez‐Zagal, Erendira A1 - Rolland, Christine A1 - Roller‐Wirnsberger, Regina E. A1 - Rosario, Nelson A1 - Romano, Antonino A1 - Rottem, Menachem A1 - Ryan, Dermot A1 - Salimäki, Johanna A1 - Sanchez‐Borges, Mario M. A1 - Sastre, Joaquin A1 - Scadding, Glenis K. A1 - Scheire, Sophie A1 - Schmid‐Grendelmeier, Peter A1 - Schünemann, Holger J. A1 - Sarquis Serpa, Faradiba A1 - Shamji, Mohamed A1 - Sisul, Juan‐Carlos A1 - Sofiev, Mikhail A1 - Solé, Dirceu A1 - Somekh, David A1 - Sooronbaev, Talant A1 - Sova, Milan A1 - Spertini, François A1 - Spranger, Otto A1 - Stellato, Cristiana A1 - Stelmach, Rafael A1 - Thibaudon, Michel A1 - To, Teresa A1 - Toumi, Mondher A1 - Usmani, Omar A1 - Valero, Antonio A. A1 - Valenta, Rudolph A1 - Valentin‐Rostan, Marylin A1 - Pereira, Marilyn Urrutia A1 - van der Kleij, Rianne A1 - Van Eerd, Michiel A1 - Vandenplas, Olivier A1 - Vasankari, Tuula A1 - Vaz Carneiro, Antonio A1 - Vezzani, Giorgio A1 - Viart, Frédéric A1 - Viegi, Giovanni A1 - Wallace, Dana A1 - Wagenmann, Martin A1 - Wang, De Yun A1 - Waserman, Susan A1 - Wickman, Magnus A1 - Williams, Dennis M. A1 - Wong, Gary A1 - Wroczynski, Piotr A1 - Yiallouros, Panayiotis K. A1 - Yusuf, Osman M. A1 - Zar, Heather J. A1 - Zeng, Stéphane A1 - Zernotti, Mario E. A1 - Zhang, Luo A1 - Shan Zhong, Nan A1 - Zidarn, Mihaela T1 - ARIA digital anamorphosis: Digital transformation of health and care in airway diseases from research to practice JF - Allergy N2 - Digital anamorphosis is used to define a distorted image of health and care that may be viewed correctly using digital tools and strategies. MASK digital anamorphosis represents the process used by MASK to develop the digital transformation of health and care in rhinitis. It strengthens the ARIA change management strategy in the prevention and management of airway disease. The MASK strategy is based on validated digital tools. Using the MASK digital tool and the CARAT online enhanced clinical framework, solutions for practical steps of digital enhancement of care are proposed. KW - ARIA KW - asthma KW - CARAT KW - digital transformation of health and care KW - MASK KW - rhinitis Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-228339 VL - 76 IS - 1 SP - 168 EP - 190 ER -