TY  - JOUR
A1  - Guggenberger, Konstanze V.
A1  - Bley, Thorsten A.
A1  - Vogt, Marius L.
A1  - Urbach, Horst
A1  - Meckel, Stephan
T1  - High-Resolution Black Blood Vessel Wall Imaging in COVID-19 Encephalopathy-Is it Really Endotheliitis?
JF  - Clinical Neuroradiology
N2  - No abstract available.
KW  - Covid-19
KW  - encephalopathy
KW  - endotheliitis
Y1  - 2022
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-264794
VL  - 32
IS  - 1
ER  - 
TY  - JOUR
A1  - Guggenberger, Konstanze Viktoria
A1  - Torre, Giulia Dalla
A1  - Ludwig, Ute
A1  - Vogel, Patrick
A1  - Weng, Andreas Max
A1  - Vogt, Marius Lothar
A1  - Fröhlich, Matthias
A1  - Schmalzing, Marc
A1  - Raithel, Esther
A1  - Forman, Christoph
A1  - Urbach, Horst
A1  - Meckel, Stephan
A1  - Bley, Thorsten Alexander
T1  - Vasa vasorum of proximal cerebral arteries after dural crossing - potential imaging confounder in diagnosing intracranial vasculitis in elderly subjects on black-blood MRI
JF  - European Radiology
N2  - Objectives
Vessel wall enhancement (VWE) may be commonly seen on MRI images of asymptomatic subjects. This study aimed to characterize the VWE of the proximal internal carotid (ICA) and vertebral arteries (VA) in a non-vasculitic elderly patient cohort.
Methods
Cranial MRI scans at 3 Tesla were performed in 43 patients (aged ≥ 50 years) with known malignancy for exclusion of cerebral metastases. For vessel wall imaging (VWI), a high-resolution compressed-sensing black-blood 3D T1-weighted fast (turbo) spin echo sequence (T1 CS-SPACE prototype) was applied post gadolinium with an isotropic resolution of 0.55 mm. Bilateral proximal intradural ICA and VA segments were evaluated for presence, morphology, and longitudinal extension of VWE.
Results
Concentric VWE of the proximal intradural ICA was found in 13 (30%) patients, and of the proximal intradural VA in 39 (91%) patients. Mean longitudinal extension of VWE after dural entry was 13 mm in the VA and 2 mm in the ICA. In 14 of 39 patients (36%) with proximal intradural VWE, morphology of VWE was suggestive of the mere presence of vasa vasorum. In 25 patients (64 %), morphology indicated atherosclerotic lesions in addition to vasa vasorum.
Conclusions
Vasa vasorum may account for concentric VWE within the proximal 2 mm of the ICA and 13 mm of the VA after dural entry in elderly subjects. Concentric VWE in these locations should not be confused with large artery vasculitis. Distal to these segments, VWE may be more likely related to pathologic conditions such as vasculitis.
KW  - vertebral artery
KW  - magnetic resonance imaging
KW  - vasa vasorum
KW  - large artery vasculitis
KW  - Atherosclerosis, intracranial arteries
Y1  - 2022
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-266524
SN  - 1432-1084
VL  - 32
IS  - 2
ER  -