TY  - JOUR
A1  - Galluzzi, L.
A1  - Bravo-San Pedro, J. M.
A1  - Vitale, I.
A1  - Aaronson, S. A.
A1  - Abrams, J. M.
A1  - Adam, D.
A1  - Alnemri, E. S.
A1  - Altucci, L.
A1  - Andrews, D.
A1  - Annicchiarico-Petruzelli, M.
A1  - Baehrecke, E. H.
A1  - Bazan, N. G.
A1  - Bertrand, M. J.
A1  - Bianchi, K.
A1  - Blagosklonny, M. V.
A1  - Blomgren, K.
A1  - Borner, C.
A1  - Bredesen, D. E.
A1  - Brenner, C.
A1  - Campanella, M.
A1  - Candi, E.
A1  - Cecconi, F.
A1  - Chan, F. K.
A1  - Chandel, N. S.
A1  - Cheng, E. H.
A1  - Chipuk, J. E.
A1  - Cidlowski, J. A.
A1  - Ciechanover, A.
A1  - Dawson, T. M.
A1  - Dawson, V. L.
A1  - De Laurenzi, V.
A1  - De Maria, R.
A1  - Debatin, K. M.
A1  - Di Daniele, N.
A1  - Dixit, V. M.
A1  - Dynlacht, B. D.
A1  - El-Deiry, W. S.
A1  - Fimia, G. M.
A1  - Flavell, R. A.
A1  - Fulda, S.
A1  - Garrido, C.
A1  - Gougeon, M. L.
A1  - Green, D. R.
A1  - Gronemeyer, H.
A1  - Hajnoczky, G.
A1  - Hardwick, J. M.
A1  - Hengartner, M. O.
A1  - Ichijo, H.
A1  - Joseph, B.
A1  - Jost, P. J.
A1  - Kaufmann, T.
A1  - Kepp, O.
A1  - Klionsky, D. J.
A1  - Knight, R. A.
A1  - Kumar, S.
A1  - Lemasters, J. J.
A1  - Levine, B.
A1  - Linkermann, A.
A1  - Lipton, S. A.
A1  - Lockshin, R. A.
A1  - López-Otín, C.
A1  - Lugli, E.
A1  - Madeo, F.
A1  - Malorni, W.
A1  - Marine, J. C.
A1  - Martin, S. J.
A1  - Martinou, J. C.
A1  - Medema, J. P.
A1  - Meier, P.
A1  - Melino, S.
A1  - Mizushima, N.
A1  - Moll, U.
A1  - Muñoz-Pinedo, C.
A1  - Nuñez, G.
A1  - Oberst, A.
A1  - Panaretakis, T.
A1  - Penninger, J. M.
A1  - Peter, M. E.
A1  - Piacentini, M.
A1  - Pinton, P.
A1  - Prehn, J. H.
A1  - Puthalakath, H.
A1  - Rabinovich, G. A.
A1  - Ravichandran, K. S.
A1  - Rizzuto, R.
A1  - Rodrigues, C. M.
A1  - Rubinsztein, D. C.
A1  - Rudel, T.
A1  - Shi, Y.
A1  - Simon, H. U.
A1  - Stockwell, B. R.
A1  - Szabadkai, G.
A1  - Tait, S. W.
A1  - Tang, H. L.
A1  - Tavernarakis, N.
A1  - Tsujimoto, Y.
A1  - Vanden Berghe, T.
A1  - Vandenabeele, P.
A1  - Villunger, A.
A1  - Wagner, E. F.
A1  - Walczak, H.
A1  - White, E.
A1  - Wood, W. G.
A1  - Yuan, J.
A1  - Zakeri, Z.
A1  - Zhivotovsky, B.
A1  - Melino, G.
A1  - Kroemer, G.
T1  - Essential versus accessory aspects of cell death: recommendations of the NCCD 2015
JF  - Cell Death and Differentiation
N2  - Cells exposed to extreme physicochemical or mechanical stimuli die in an uncontrollable manner, as a result of their immediate structural breakdown. Such an unavoidable variant of cellular demise is generally referred to as 'accidental cell death' (ACD). In most settings, however, cell death is initiated by a genetically encoded apparatus, correlating with the fact that its course can be altered by pharmacologic or genetic interventions. 'Regulated cell death' (RCD) can occur as part of physiologic programs or can be activated once adaptive responses to perturbations of the extracellular or intracellular microenvironment fail. The biochemical phenomena that accompany RCD may be harnessed to classify it into a few subtypes, which often (but not always) exhibit stereotyped morphologic features. Nonetheless, efficiently inhibiting the processes that are commonly thought to cause RCD, such as the activation of executioner caspases in the course of apoptosis, does not exert true cytoprotective effects in the mammalian system, but simply alters the kinetics of cellular demise as it shifts its morphologic and biochemical correlates. Conversely, bona fide cytoprotection can be achieved by inhibiting the transduction of lethal signals in the early phases of the process, when adaptive responses are still operational. Thus, the mechanisms that truly execute RCD may be less understood, less inhibitable and perhaps more homogeneous than previously thought. Here, the Nomenclature Committee on Cell Death formulates a set of recommendations to help scientists and researchers to discriminate between essential and accessory aspects of cell death.
Y1  - 2015
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-121207
VL  - 22
ER  - 
TY  - JOUR
A1  - De Palma, Adriana
A1  - Abrahamczyk, Stefan
A1  - Aizen, Marcelo A.
A1  - Albrecht, Matthias
A1  - Basset, Yves
A1  - Bates, Adam
A1  - Blake, Robin J.
A1  - Boutin, Céline
A1  - Bugter, Rob
A1  - Connop, Stuart
A1  - Cruz-López, Leopoldo
A1  - Cunningham, Saul A.
A1  - Darvill, Ben
A1  - Diekötter, Tim
A1  - Dorn, Silvia
A1  - Downing, Nicola
A1  - Entling, Martin H.
A1  - Farwig, Nina
A1  - Felicioli, Antonio
A1  - Fonte, Steven J.
A1  - Fowler, Robert
A1  - Franzen, Markus Franzén
A1  - Goulson, Dave
A1  - Grass, Ingo
A1  - Hanley, Mick E.
A1  - Hendrix, Stephen D.
A1  - Herrmann, Farina
A1  - Herzog, Felix
A1  - Holzschuh, Andrea
A1  - Jauker, Birgit
A1  - Kessler, Michael
A1  - Knight, M. E.
A1  - Kruess, Andreas
A1  - Lavelle, Patrick
A1  - Le Féon, Violette
A1  - Lentini, Pia
A1  - Malone, Louise A.
A1  - Marshall, Jon
A1  - Martínez Pachón, Eliana
A1  - McFrederick, Quinn S.
A1  - Morales, Carolina L.
A1  - Mudri-Stojnic, Sonja
A1  - Nates-Parra, Guiomar
A1  - Nilsson, Sven G.
A1  - Öckinger, Erik
A1  - Osgathorpe, Lynne
A1  - Parra-H, Alejandro
A1  - Peres, Carlos A.
A1  - Persson, Anna S.
A1  - Petanidou, Theodora
A1  - Poveda, Katja
A1  - Power, Eileen F.
A1  - Quaranta, Marino
A1  - Quintero, Carolina
A1  - Rader, Romina
A1  - Richards, Miriam H.
A1  - Roulston, T’ai
A1  - Rousseau, Laurent
A1  - Sadler, Jonathan P.
A1  - Samnegård, Ulrika
A1  - Schellhorn, Nancy A.
A1  - Schüepp, Christof
A1  - Schweiger, Oliver
A1  - Smith-Pardo, Allan H.
A1  - Steffan-Dewenter, Ingolf
A1  - Stout, Jane C.
A1  - Tonietto, Rebecca K.
A1  - Tscharntke, Teja
A1  - Tylianakis, Jason M.
A1  - Verboven, Hans A. F.
A1  - Vergara, Carlos H.
A1  - Verhulst, Jort
A1  - Westphal, Catrin
A1  - Yoon, Hyung Joo
A1  - Purvis, Andy
T1  - Predicting bee community responses to land-use changes: Effects of geographic and taxonomic biases
JF  - Scientific Reports
N2  - Land-use change and intensification threaten bee populations worldwide, imperilling pollination services. Global models are needed to better characterise, project, and mitigate bees' responses to these human impacts. The available data are, however, geographically and taxonomically unrepresentative; most data are from North America and Western Europe, overrepresenting bumblebees and raising concerns that model results may not be generalizable to other regions and taxa. To assess whether the geographic and taxonomic biases of data could undermine effectiveness of models for conservation policy, we have collated from the published literature a global dataset of bee diversity at sites facing land-use change and intensification, and assess whether bee responses to these pressures vary across 11 regions (Western, Northern, Eastern and Southern Europe; North, Central and South America; Australia and New Zealand; South East Asia; Middle and Southern Africa) and between bumblebees and other bees. Our analyses highlight strong regionally-based responses of total abundance, species richness and Simpson's diversity to land use, caused by variation in the sensitivity of species and potentially in the nature of threats. These results suggest that global extrapolation of models based on geographically and taxonomically restricted data may underestimate the true uncertainty, increasing the risk of ecological surprises.
KW  - bee community
KW  - land-use change
KW  - intensification
KW  - geographic biases
KW  - taxonomic biases
KW  - global dataset
Y1  - 2016
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-167642
VL  - 6
ER  -