TY - JOUR A1 - Stöckli, K. A. A1 - Lottspeich, F. A1 - Sendtner, Michael A1 - Masiakowski, P. A1 - Carroll, Patrick A1 - Götz, Rudolf A1 - Lindholm, D. A1 - Thoenen, Hans T1 - Molecular cloning, expression and regional distribution of rat ciliary neurotrophic factor N2 - CILIARY neurotrophic factor (CNTF) was originally characterized as a survival factor for chick ciliary neurons in vitro. More recently, it was shown to promote the survival of a variety of otherneuronal cell types and to affect the differentiation of E7 chick sympathetic neurons by inhibiting their proliferation and by inducing the expression of yasoactiYe intestinal peptide immunoreactiyity (VIP-IR). In cultures of dissociated sympathetic neurons from newborn rats, CNTF induces cholinergic differentiation as shown by increased levels of choline acetyltransferase (ChAT. Y1 - 1989 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-34229 ER -