TY  - JOUR
A1  - Ye, Liqing
A1  - Ambi, Uddhav B.
A1  - Olguin-Nava, Marco
A1  - Gribling-Burrer, Anne-Sophie
A1  - Ahmad, Shazeb
A1  - Bohn, Patrick
A1  - Weber, Melanie M.
A1  - Smyth, Redmond P.
T1  - RNA structures and their role in selective genome packaging
JF  - Viruses
N2  - To generate infectious viral particles, viruses must specifically select their genomic RNA from milieu that contains a complex mixture of cellular or non-genomic viral RNAs. In this review, we focus on the role of viral encoded RNA structures in genome packaging. We first discuss how packaging signals are constructed from local and long-range base pairings within viral genomes, as well as inter-molecular interactions between viral and host RNAs. Then, how genome packaging is regulated by the biophysical properties of RNA. Finally, we examine the impact of RNA packaging signals on viral evolution.
KW  - RNA virus
KW  - RNA
KW  - RNA structure
KW  - genome packaging
KW  - viral assembly
KW  - evolution
Y1  - 2021
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-246101
SN  - 1999-4915
VL  - 13
IS  - 9
ER  -