TY  - JOUR
A1  - Zhang, Xin
A1  - Wu, Wei
A1  - Li, Gang
A1  - Wen, Lin
A1  - Sun, Qing
A1  - Ji, An-Chun
T1  - Phase diagram of interacting Fermi gas in spin-orbit coupled square lattices
JF  - New Journal of Physics
N2  - The spin-orbit (SO) coupled optical lattices have attracted considerable interest. In this paper, we investigate the phase diagram of the interacting Fermi gas with Rashba-type spin-orbit coupling (SOC) on a square optical lattice. The phase diagram is investigated in a wide range of atomic interactions and SOC strength within the framework of the cluster dynamical mean-field theory (CDMFT). We show that the interplay between the atomic interactions and SOC results in a rich phase diagram. In the deep Mott insulator regime, the SOC can induce diverse spin ordered phases. Whereas near the metal-insulator transition (MIT), the SOC tends to destroy the conventional antiferromagnetic fluctuations, giving rise to distinctive features of the MIT. Furthermore, the strong fluctuations arising from SOC may destroy the magnetic orders and trigger an order to disorder transition in close proximity of the MIT.
KW  - ultracold
KW  - hubbard-model
KW  - physics transition
KW  - metal-insulator transition
KW  - cluster dynamical mean-field theory
KW  - atomic gases
KW  - mean-field theory
KW  - mott insulator
KW  - optical lattice
KW  - weak ferromagnetism
KW  - quantum gases
KW  - superfluid
KW  - spin-orbit coupling
Y1  - 2015
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-151475
VL  - 17
IS  - 073036
ER  - 
TY  - JOUR
A1  - Sun, Wei
A1  - Starly, Binil
A1  - Daly, Andrew C
A1  - Burdick, Jason A
A1  - Groll, Jürgen
A1  - Skeldon, Gregor
A1  - Shu, Wenmiao
A1  - Sakai, Yasuyuki
A1  - Shinohara, Marie
A1  - Nishikawa, Masaki
A1  - Jang, Jinah
A1  - Cho, Dong-Woo
A1  - Nie, Minghao
A1  - Takeuchi, Shoji
A1  - Ostrovidov, Serge
A1  - Khademhosseini, Ali
A1  - Kamm, Roger D
A1  - Mironov, Vladimir
A1  - Moroni, Lorenzo
A1  - Ozbolat, Ibrahim T
T1  - The bioprinting roadmap
JF  - Biofabrication
N2  - This bioprinting roadmap features salient advances in selected applications of the technique and highlights the status of current developments and challenges, as well as envisioned advances in science and technology, to address the challenges to the young and evolving technique. The topics covered in this roadmap encompass the broad spectrum of bioprinting; from cell expansion and novel bioink development to cell/stem cell printing, from organoid-based tissue organization to bioprinting of human-scale tissue structures, and from building cell/tissue/organ-on-a-chip to biomanufacturing of multicellular engineered living systems. The emerging application of printing-in-space and an overview of bioprinting technologies are also included in this roadmap. Due to the rapid pace of methodological advancements in bioprinting techniques and wide-ranging applications, the direction in which the field should advance is not immediately clear. This bioprinting roadmap addresses this unmet need by providing a comprehensive summary and recommendations useful to experienced researchers and newcomers to the field.
KW  - biofabrication
KW  - bioprinting
KW  - cell printing
KW  - biological models
KW  - disease models
KW  - organoids
KW  - organ-on-a-chip
Y1  - 2020
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-254027
VL  - 12
IS  - 2
ER  - 
TY  - JOUR
A1  - Benhalevy, Daniel
A1  - Gupta, Sanjay K.
A1  - Danan, Charles H.
A1  - Ghosal, Suman
A1  - Sun, Hong-Wei
A1  - Kazemeier, Hinke G.
A1  - Paeschke, Katrin
A1  - Hafner, Markus
A1  - Juranek, Stefan A.
T1  - The Human CCHC-type Zinc Finger Nucleic Acid-Binding Protein Binds G-Rich Elements in Target mRNA Coding Sequences and Promotes Translation
JF  - Cell Reports
N2  - The CCHC-type zinc finger nucleic acid-binding protein (CNBP/ZNF9) is conserved in eukaryotes and is essential for embryonic development in mammals. It has been implicated in transcriptional, as well as post-transcriptional, gene regulation; however, its nucleic acid ligands and molecular function remain elusive. Here, we use multiple systems-wide approaches to identify CNBP targets and function. We used photoactivatable ribonucleoside-enhanced crosslinking and immunoprecipitation (PAR-CLIP) to identify 8,420 CNBP binding sites on 4,178 mRNAs. CNBP preferentially bound G-rich elements in the target mRNA coding sequences, most of which were previously found to form G-quadruplex and other stable structures in vitro. Functional analyses, including RNA sequencing, ribosome profiling, and quantitative mass spectrometry, revealed that CNBP binding did not influence target mRNA abundance but rather increased their translational efficiency. Considering that CNBP binding prevented G-quadruplex structure formation in vitro, we hypothesize that CNBP is supporting translation by resolving stable structures on mRNAs.
KW  - PAR-CLIP
KW  - ribosome profiling
KW  - translational regulation
KW  - posttranscriptional gene regulation
KW  - zinc-finger
KW  - RNA binding protein
KW  - CLIP-seq
Y1  - 2017
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-171122
VL  - 18
IS  - 12
ER  -