TY  - JOUR
A1  - Jockel-Schneider, Yvonne
A1  - Harks, Inga
A1  - Haubitz, Imme
A1  - Fickl, Stefan
A1  - Eigenthaler, Martin
A1  - Schlagenhauf, Ulrich
A1  - Baulmann, Johannes
T1  - Arterial Stiffness and Pulse Wave Reflection Are Increased in Patients Suffering from Severe Periodontitis
JF  - PLOS ONE
N2  - Aim: This single blind cross-sectional study compared the vascular health of subjects suffering from severe chronic periodontitis, severe aggressive periodontitis and periodontal healthy controls by evaluating pulse wave velocity (PWV), augmentation index (AIx) and pulse pressure amplification (PPA).
Material and Methods: In a total of 158 subjects, 92 suffering from severe periodontitis and 66 matched periodontal healthy controls, PWV, AIx, central and peripheral blood pressure were recorded using an oscillometric device (Arteriograph).
Results: Subjects suffering from severe chronic or aggressive periodontitis exhibited significantly higher PWV (p = 0.00004), higher AIx (p = 0.0049) and lower PPA (p = 0.028) than matched periodontal healthy controls.
Conclusions: The results of this study confirm the association between periodontal inflammation and increased cardiovascular risk shown by impaired vascular health in case of severe periodontitis. As impaired vascular health is a common finding in patients suffering from severe periodontal disease a concomitant routine cardiovascular evaluation may be advised.
KW  - periodontal diseases
KW  - diagnostic medicine
KW  - teeth
KW  - stiffness
KW  - reflection
KW  - periodontitis
KW  - blood pressure
KW  - hypertension
Y1  - 2014
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-119459
SN  - 1932-6203
VL  - 9
IS  - 8
ER  - 
TY  - JOUR
A1  - Schlagenhauf, Ulrich
A1  - Jakob, Lena
A1  - Eigenthaler, Martin
A1  - Segerer, Sabine
A1  - Jockel-Schneider, Yvonne
A1  - Rehn, Monika
T1  - Regular consumption of Lactobacillus reuteri-containing lozenges reduces pregnancy gingivitis: an RCT
JF  - Journal of Clinical Periodontology
N2  - Aim: 
This randomized controlled trial assessed the impact of Lactobacillus reuteri on pregnancy gingivitis in healthy women. 

Materials and Methods: 
Forty-five healthy women (24 test/21 placebo) with pregnancy gingivitis in the third trimester of pregnancy were enrolled. At baseline Gingival Index (GI) and Plaque Index (PlI) were assessed at the Ramfjord teeth and venous blood taken for TNF-alpha analysis. Subsequently participants were randomly provided with lozenges to be consumed 2 9 daily until birth (approx. 7 weeks) containing >= 10(8) CFU L. reuteri ATCC PTA 5289 and >= 10(8) CFU L. reuteri DSM 17938 (test) or being devoid of L. reuteri (placebo). Within 2 days after birth recording of GI, PlI and blood sampling were repeated. 

Results: 
At baseline, mean GI and mean PlI did not differ significantly between both groups. In the test group mean TNF-alpha serum level was significantly (p < 0.02) lower than in the placebo group. At reevaluation, mean GI and mean PlI of the test group were both significantly (p < 0.0001) lower than in the placebo group. Mean TNF-alpha serum level did no longer differ significantly between the groups. 

Conclusions: 
The consumption of L. reuteri lozenges may be a useful adjunct in the control of pregnancy gingivitis.
KW  - chronic periodontitis
KW  - probiotic lozenges
KW  - subgingival
KW  - bacteria
KW  - postpartum
KW  - microbiota
KW  - disease
KW  - L. reuteri
KW  - plaque
KW  - pregnancy
KW  - pregnancy gingivitis
Y1  - 2016
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-186783
VL  - 43
IS  - 11
ER  -