TY - INPR A1 - Dandekar, Thomas T1 - Biological heuristics applied to cosmology suggests a condensation nucleus as start of our universe and inflation cosmology replaced by a period of rapid Weiss domain-like crystal growth N2 - Cosmology often uses intricate formulas and mathematics to derive new theories and concepts. We do something different in this paper: We look at biological processes and derive from these heuristics so that the revised cosmology agrees with astronomical observations but does also agree with standard biological observations. We show that we then have to replace any type of singularity at the start of the universe by a condensation nucleus and that the very early period of the universe usually assumed to be inflation has to be replaced by a period of rapid crystal growth as in Weiss magnetization domains. Impressively, these minor modifications agree well with astronomical observations including removing the strong inflation perturbations which were never observed in the recent BICEP2 experiments. Furthermore, looking at biological principles suggests that such a new theory with a condensation nucleus at start and a first rapid phase of magnetization-like growth of the ordered, physical laws obeying lattice we live in is in fact the only convincing theory of the early phases of our universe that also is compatible with current observations. We show in detail in the following that such a process of crystal creation, breaking of new crystal seeds and ultimate evaporation of the present crystal readily leads over several generations to an evolution and selection of better, more stable and more self-organizing crystals. Moreover, this explains the “fine-tuning” question why our universe is fine-tuned to favor life: Our Universe is so self-organizing to have enough offspring and the detailed physics involved is at the same time highly favorable for all self-organizing processes including life. This biological theory contrasts with current standard inflation cosmologies. The latter do not perform well in explaining any phenomena of sophisticated structure creation or self-organization. As proteins can only thermodynamically fold by increasing the entropy in the solution around them we suggest for cosmology a condensation nucleus for a universe can form only in a “chaotic ocean” of string-soup or quantum foam if the entropy outside of the nucleus rapidly increases. We derive an interaction potential for 1 to n-dimensional strings or quantum-foams and show that they allow only 1D, 2D, 4D or octonion interactions. The latter is the richest structure and agrees to the E8 symmetry fundamental to particle physics and also compatible with the ten dimensional string theory E8 which is part of the M-theory. Interestingly, any other interactions of other dimensionality can be ruled out using Hurwitz compositional theorem. Crystallization explains also extremely well why we have only one macroscopic reality and where the worldlines of alternative trajectories exist: They are in other planes of the crystal and for energy reasons they crystallize mostly at the same time, yielding a beautiful and stable crystal. This explains decoherence and allows to determine the size of Planck´s quantum h (very small as separation of crystal layers by energy is extremely strong). Ultimate dissolution of real crystals suggests an explanation for dark energy agreeing with estimates for the “big rip”. The halo distribution of dark matter favoring galaxy formation is readily explained by a crystal seed starting with unit cells made of normal and dark matter. That we have only matter and not antimatter can be explained as there may be right handed mattercrystals and left-handed antimatter crystals. Similarly, real crystals are never perfect and we argue that exactly such irregularities allow formation of galaxies, clusters and superclusters. Finally, heuristics from genetics suggest to look for a systems perspective to derive correct vacuum and Higgs Boson energies. KW - heuristics KW - inflation KW - cosmology KW - crystallization KW - crystal growth KW - E8 symmetry KW - Hurwitz theorem KW - evolution KW - Lee Smolin Y1 - 2019 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-183945 ER - TY - THES A1 - Ostermayer, Ludwig T1 - Integration of Prolog and Java with the Connector Architecture CAPJa T1 - Integration von Prolog und Java mit Hilfe der Connector Architecture CAPJa N2 - Modern software is often realized as a modular combination of subsystems for, e. g., knowledge management, visualization, verification, or the interaction with users. As a result, software libraries from possibly different programming languages have to work together. Even more complex the case is if different programming paradigms have to be combined. This type of diversification of programming languages and paradigms in just one software application can only be mastered by mechanisms for a seamless integration of the involved programming languages. However, the integration of the common logic programming language Prolog and the popular object-oriented programming language Java is complicated by various interoperability problems which stem on the one hand from the paradigmatic gap between the programming languages, and on the other hand, from the diversity of the available Prolog systems. The subject of the thesis is the investigation of novel mechanisms for the integration of logic programming in Prolog and object–oriented programming in Java. We are particularly interested in an object–oriented, uniform approach which is not specific to just one Prolog system. Therefore, we have first identified several important criteria for the seamless integration of Prolog and Java from the object–oriented perspective. The main contribution of the thesis is a novel integration framework called the Connector Architecture for Prolog and Java (CAPJa). The framework is completely implemented in Java and imposes no modifications to the Java Virtual Machine or Prolog. CAPJa provides a semi–automated mechanism for the integration of Prolog predicates into Java. For compact, readable, and object–oriented queries to Prolog, CAPJa exploits lambda expressions with conditional and relational operators in Java. The communication between Java and Prolog is based on a fully automated mapping of Java objects to Prolog terms, and vice versa. In Java, an extensible system of gateways provides connectivity with various Prolog system and, moreover, makes any connected Prolog system easily interchangeable, without major adaption in Java. N2 - Moderne Software ist oft modular zusammengesetzt aus Subsystemen zur Wissensverwaltung, Visualisierung, Verfikation oder Benutzerinteraktion. Dabei müssen Programmbibliotheken aus möglicherweise verschiedenen Programmiersprachen miteinander zusammenarbeiten. Noch komplizierter ist der Fall, wenn auch noch verschiedene Programmierparadigmen miteinander kombiniert werden. Diese Art der Diversifikation an Programmiersprachen und –paradigmen in nur einer Software kann nur von nahtlosen Integrationsmechansimen für die beteiligten Programmiersprachen gemeistert werden. Gerade die Einbindung der gängigen Logikprogrammiersprache Prolog und der populären objektorientierten Programmiersprache Java wird durch zahlreiche Kompatibilitätsprobleme erschwert, welche auf der einen Seite von paradigmatischen Unterschieden der beiden Programmiersprachen herrühren und auf der anderen Seite von der Vielfalt der erhältlichen Prologimplementierungen. Gegenstand dieser Arbeit ist die Untersuchung von neuartigen Mechanismen für die Zusammenführung von Logikprogrammierung in Prolog und objektorienter Programmierung in Java. Besonders interessiert uns dabei ein objektorientierter, einheitlicher Ansatz, der nicht auf eine konkrete Prologimplementierung festgelegt ist. Aus diesem Grund haben wir zunächst wichtige Kriterien für die nahtlose Integration von Prolog und Java aus der objetorientierten Sicht identifziert. Der Hauptbeitrag dieser Arbeit ist ein neuartiges Integrationssystems, welches Connector Architecture for Prolog and Java (CAPJa) heißt. Das System ist komplett in Java implementiert und benötigt keine Anpassungen der Java Virtual Machine oder Prolog. CAPJa stellt einen halbautomatischen Mechanismus zur Vernetzung von Prolog Prädikaten mit Java zur Verfügung. Für kompakte, lesbare und objektorientierte Anfragen an Prolog nutzt CAPJa Lambdaausdrücke mit logischen und relationalen Operatoren in Java. Die Kommunikation zwischen Java und Prolog basiert auf einer automatisierten Abbildung von Java Objekten auf Prolog Terme, und umgekehrt. In Java bietet ein erweiterbares System von Schnittstellen Konnektivität zu einer Vielzahl an Prologimplmentierung und macht darüber hinaus jede verbundene Prologimplementierung einfach austauschbar, und zwar ohne größere Anpassung in Java. KW - Logische Programmierung KW - Objektorientierte Programmierung KW - PROLOG KW - Java KW - Multi-Paradigm Programming KW - Logic Programming KW - Object-Oriented Programming KW - Multi-Paradigm Programming Framework Y1 - 2017 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-150713 ER - TY - JOUR A1 - Kunz, Meik A1 - Liang, Chunguang A1 - Nilla, Santosh A1 - Cecil, Alexander A1 - Dandekar, Thomas T1 - The drug-minded protein interaction database (DrumPID) for efficient target analysis and drug development JF - Database N2 - The drug-minded protein interaction database (DrumPID) has been designed to provide fast, tailored information on drugs and their protein networks including indications, protein targets and side-targets. Starting queries include compound, target and protein interactions and organism-specific protein families. Furthermore, drug name, chemical structures and their SMILES notation, affected proteins (potential drug targets), organisms as well as diseases can be queried including various combinations and refinement of searches. Drugs and protein interactions are analyzed in detail with reference to protein structures and catalytic domains, related compound structures as well as potential targets in other organisms. DrumPID considers drug functionality, compound similarity, target structure, interactome analysis and organismic range for a compound, useful for drug development, predicting drug side-effects and structure–activity relationships. KW - drug-minded protein KW - database Y1 - 2016 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-147369 VL - 2016 ER - TY - JOUR A1 - Buchheim, Mark A. A1 - Keller, Alexander A1 - Koetschan, Christian A1 - Förster, Frank A1 - Merget, Benjamin A1 - Wolf, Matthias T1 - Internal Transcribed Spacer 2 (nu ITS2 rRNA) Sequence-Structure Phylogenetics: Towards an Automated Reconstruction of the Green Algal Tree of Life JF - PLoS ONE N2 - Background: Chloroplast-encoded genes (matK and rbcL) have been formally proposed for use in DNA barcoding efforts targeting embryophytes. Extending such a protocol to chlorophytan green algae, though, is fraught with problems including non homology (matK) and heterogeneity that prevents the creation of a universal PCR toolkit (rbcL). Some have advocated the use of the nuclear-encoded, internal transcribed spacer two (ITS2) as an alternative to the traditional chloroplast markers. However, the ITS2 is broadly perceived to be insufficiently conserved or to be confounded by introgression or biparental inheritance patterns, precluding its broad use in phylogenetic reconstruction or as a DNA barcode. A growing body of evidence has shown that simultaneous analysis of nucleotide data with secondary structure information can overcome at least some of the limitations of ITS2. The goal of this investigation was to assess the feasibility of an automated, sequence-structure approach for analysis of IT2 data from a large sampling of phylum Chlorophyta. Methodology/Principal Findings: Sequences and secondary structures from 591 chlorophycean, 741 trebouxiophycean and 938 ulvophycean algae, all obtained from the ITS2 Database, were aligned using a sequence structure-specific scoring matrix. Phylogenetic relationships were reconstructed by Profile Neighbor-Joining coupled with a sequence structure-specific, general time reversible substitution model. Results from analyses of the ITS2 data were robust at multiple nodes and showed considerable congruence with results from published phylogenetic analyses. Conclusions/Significance: Our observations on the power of automated, sequence-structure analyses of ITS2 to reconstruct phylum-level phylogenies of the green algae validate this approach to assessing diversity for large sets of chlorophytan taxa. Moreover, our results indicate that objections to the use of ITS2 for DNA barcoding should be weighed against the utility of an automated, data analysis approach with demonstrated power to reconstruct evolutionary patterns for highly divergent lineages. KW - RBCL Gene-sequences KW - Colonial volvocales chlorophyta KW - 26S RDNA Data KW - Land plants KW - Molecular systematics KW - Secondary structure KW - Nuclear RDNA KW - DNA KW - Barcodes KW - Dasycladales chlorophyta KW - Profile distances Y1 - 2011 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-140866 VL - 6 IS - 2 ER - TY - THES A1 - Baier, Herbert T1 - Operators of Higher Order N2 - Motivated by results on interactive proof systems we investigate the computational power of quantifiers applied to well-known complexity classes. In special, we are interested in existential, universal and probabilistic bounded error quantifiers ranging over words and sets of words, i.e. oracles if we think in a Turing machine model. In addition to the standard oracle access mechanism, we also consider quantifiers ranging over oracles to which access is restricted in a certain way. N2 - Angeregt durch die Resultate über interaktive Beweissysteme untersuchen wir Quantoren in Anwendung auf bereits bekannte Komplexitätsklassen hinsichtlich ihrer dadurch gegebenen Berechnungsmächtigkeit. Von besonderem Interesse sind dabei existentielle und universelle Quantoren sowie Quantoren mit begrenzter Fehlerwahrscheinlichkeit, die alle über Wörter oder Wortmengen (Orakel im Kontext der Turingmaschinen) quantifizieren. Außer in Bezug auf den Standardmechanismus eines Orakelzugriffs werden auch Quantifizierungen über Orakel, für deren Zugriff gewisse Beschränkungen bestehen, betrachtet. KW - Komplexitätstheorie KW - Quantor KW - Operator KW - Komplexitätsklasse Y1 - 1998 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-140799 SN - 3-8265-4008-5 PB - Shaker Verlag ER - TY - JOUR A1 - Hurtienne, Jörn T1 - Inter-coder reliability of categorising force-dynamic events in human-technology interaction N2 - Two studies are reported that investigate how readily accessible and applicable ten force-dynamic categories are to novices in describing short episodes of human-technology interaction (Study 1) and that establish a measure of inter-coder reliability when re-classifying these episodes into force-dynamic categories (Study 2). The results of the first study show that people can easily and confidently relate their experiences with technology to the definitions of force-dynamic events (e.g. “The driver released the handbrake” as an example of restraint removal). The results of the second study show moderate agreement between four expert coders across all ten force-dynamic categories (Cohen’s kappa = .59) when re-classifying these episodes. Agreement values for single force-dynamic categories ranged between ‘fair’ and ‘almost perfect’, i.e. between kappa = .30 and .95. Agreement with the originally intended classifications of study 1 was higher than the pure inter-coder reliabilities. Single coders achieved an average kappa of .71, indicating substantial agreement. Using more than one coder increased kappas to almost perfect: up to .87 for four coders. A qualitative analysis of the predicted versus the observed number of category confusions revealed that about half of the category disagreement could be predicted from strong overlaps in the definitions of force-dynamic categories. From the quantitative and qualitative results, guidelines are derived to aid the better training of coders in order to increase inter-coder reliability. KW - inter-coder reliability KW - force dynamics KW - image schemas KW - humantechnology interaction Y1 - 2013 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-194127 SN - 2197-2796 SN - 2197-2788 N1 - This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively. VL - 1 IS - 1 ER - TY - JOUR A1 - Gehrke, Alexander A1 - Balbach, Nico A1 - Rauch, Yong-Mi A1 - Degkwitz, Andreas A1 - Puppe, Frank T1 - Erkennung von handschriftlichen Unterstreichungen in Alten Drucken JF - Bibliothek Forschung und Praxis N2 - Die Erkennung handschriftlicher Artefakte wie Unterstreichungen in Buchdrucken ermöglicht Rückschlüsse auf das Rezeptionsverhalten und die Provenienzgeschichte und wird auch für eine OCR benötigt. Dabei soll zwischen handschriftlichen Unterstreichungen und waagerechten Linien im Druck (z. B. Trennlinien usw.) unterschieden werden, da letztere nicht ausgezeichnet werden sollen. Im Beitrag wird ein Ansatz basierend auf einem auf Unterstreichungen trainierten Neuronalen Netz gemäß der U-Net Architektur vorgestellt, dessen Ergebnisse in einem zweiten Schritt mit heuristischen Regeln nachbearbeitet werden. Die Evaluationen zeigen, dass Unterstreichungen sehr gut erkannt werden, wenn bei der Binarisierung der Scans nicht zu viele Pixel der Unterstreichung wegen geringem Kontrast verloren gehen. Zukünftig sollen die Worte oberhalb der Unterstreichung mit OCR transkribiert werden und auch andere Artefakte wie handschriftliche Notizen in alten Drucken erkannt werden. N2 - The recognition of handwritten artefacts like underlines in historical printings allows inference on the reception and provenance history and is necessary for OCR (optical character recognition). In this context it is important to differentiate between handwritten and printed lines, since the latter are common in printings, but should be ignored. We present an approach based on neural nets with the U-Net architecture, whose segmentation results are post processed with heuristic rules. The evaluations show that handwritten underlines are very well recognized if the binarisation of the scans is adequate. Future work includes transcription of the underlined words with OCR and recognition of other artefacts like handwritten notes in historical printings. T2 - Recognition of handwritten underlines in historical printings KW - Brüder Grimm Privatbibliothek KW - Erkennung handschriftlicher Artefakte KW - Convolutional Neural Network KW - regelbasierte Nachbearbeitung KW - Grimm brothers personal library KW - handwritten artefact recognition KW - convolutional neural network KW - rule based post processing Y1 - 2019 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-193377 SN - 1865-7648 SN - 0341-4183 N1 - Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich. VL - 43 IS - 3 SP - 447 EP - 452 ER - TY - JOUR A1 - Ali, Qasim A1 - Montenegro, Sergio T1 - Decentralized control for scalable quadcopter formations JF - International Journal of Aerospace Engineering N2 - An innovative framework has been developed for teamwork of two quadcopter formations, each having its specified formation geometry, assigned task, and matching control scheme. Position control for quadcopters in one of the formations has been implemented through a Linear Quadratic Regulator Proportional Integral (LQR PI) control scheme based on explicit model following scheme. Quadcopters in the other formation are controlled through LQR PI servomechanism control scheme. These two control schemes are compared in terms of their performance and control effort. Both formations are commanded by respective ground stations through virtual leaders. Quadcopters in formations are able to track desired trajectories as well as hovering at desired points for selected time duration. In case of communication loss between ground station and any of the quadcopters, the neighboring quadcopter provides the command data, received from the ground station, to the affected unit. Proposed control schemes have been validated through extensive simulations using MATLAB®/Simulink® that provided favorable results. KW - scalable quadcopter Y1 - 2016 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-146704 VL - 2016 ER - TY - JOUR A1 - Ali, Qasim A1 - Montenegro, Sergio T1 - Explicit Model Following Distributed Control Scheme for Formation Flying of Mini UAVs JF - IEEE Access N2 - A centralized heterogeneous formation flight position control scheme has been formulated using an explicit model following design, based on a Linear Quadratic Regulator Proportional Integral (LQR PI) controller. The leader quadcopter is a stable reference model with desired dynamics whose output is perfectly tracked by the two wingmen quadcopters. The leader itself is controlled through the pole placement control method with desired stability characteristics, while the two followers are controlled through a robust and adaptive LQR PI control method. Selected 3-D formation geometry and static stability are maintained under a number of possible perturbations. With this control scheme, formation geometry may also be switched to any arbitrary shape during flight, provided a suitable collision avoidance mechanism is incorporated. In case of communication loss between the leader and any of the followers, the other follower provides the data, received from the leader, to the affected follower. The stability of the closed-loop system has been analyzed using singular values. The proposed approach for the tightly coupled formation flight of mini unmanned aerial vehicles has been validated with the help of extensive simulations using MATLAB/Simulink, which provided promising results. KW - quadcopter KW - robustness KW - intelligent vehicles KW - rotors KW - mathematical model KW - aerodynamics KW - adaptation models KW - vehicle dynamics KW - unmanned aerial vehicle KW - distributed control KW - formation flight KW - model following Y1 - 2016 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-146061 N1 - (c) 2016 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other users, including reprinting/ republishing this material for advertising or promotional purposes, creating new collective works for resale or redistribution to servers or lists, or reuse of any copyrighted components of this work in other works VL - 4 IS - 397-406 ER - TY - JOUR A1 - Lugrin, Jean-Luc A1 - Latoschik, Marc Erich A1 - Habel, Michael A1 - Roth, Daniel A1 - Seufert, Christian A1 - Grafe, Silke T1 - Breaking Bad Behaviors: A New Tool for Learning Classroom Management Using Virtual Reality JF - Frontiers in ICT N2 - This article presents an immersive virtual reality (VR) system for training classroom management skills, with a specific focus on learning to manage disruptive student behavior in face-to-face, one-to-many teaching scenarios. The core of the system is a real-time 3D virtual simulation of a classroom populated by twenty-four semi-autonomous virtual students. The system has been designed as a companion tool for classroom management seminars in a syllabus for primary and secondary school teachers. This will allow lecturers to link theory with practice using the medium of VR. The system is therefore designed for two users: a trainee teacher and an instructor supervising the training session. The teacher is immersed in a real-time 3D simulation of a classroom by means of a head-mounted display and headphone. The instructor operates a graphical desktop console, which renders a view of the class and the teacher whose avatar movements are captured by a marker less tracking system. This console includes a 2D graphics menu with convenient behavior and feedback control mechanisms to provide human-guided training sessions. The system is built using low-cost consumer hardware and software. Its architecture and technical design are described in detail. A first evaluation confirms its conformance to critical usability requirements (i.e., safety and comfort, believability, simplicity, acceptability, extensibility, affordability, and mobility). Our initial results are promising and constitute the necessary first step toward a possible investigation of the efficiency and effectiveness of such a system in terms of learning outcomes and experience. KW - virtual reality training KW - immersive classroom management KW - immersive classroom KW - virtual agent interaction KW - student simulation Y1 - 2016 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-147945 VL - 3 IS - 26 ER -