TY - THES A1 - Fink, Martin T1 - Crossings, Curves, and Constraints in Graph Drawing T1 - Kreuzungen, Kurven und Constraints beim Zeichnen von Graphen N2 - In many cases, problems, data, or information can be modeled as graphs. Graphs can be used as a tool for modeling in any case where connections between distinguishable objects occur. Any graph consists of a set of objects, called vertices, and a set of connections, called edges, such that any edge connects a pair of vertices. For example, a social network can be modeled by a graph by transforming the users of the network into vertices and friendship relations between users into edges. Also physical networks like computer networks or transportation networks, for example, the metro network of a city, can be seen as graphs. For making graphs and, thereby, the data that is modeled, well-understandable for users, we need a visualization. Graph drawing deals with algorithms for visualizing graphs. In this thesis, especially the use of crossings and curves is investigated for graph drawing problems under additional constraints. The constraints that occur in the problems investigated in this thesis especially restrict the positions of (a part of) the vertices; this is done either as a hard constraint or as an optimization criterion. N2 - Viele Probleme, Informationen oder Daten lassen sich mit Hilfe von Graphen modellieren. Graphen können überall dort eingesetzt werden, wo Verbindungen zwischen unterscheidbaren Objekten auftreten. Ein Graph besteht aus einer Menge von Objekten, genannt Knoten, und einer Menge von Verbindungen, genannt Kanten, zwischen je einem Paar von Knoten. Ein soziales Netzwerk lässt sich etwa als Graph modellieren, indem die teilnehmenden Personen als Knoten und Freundschaftsbeziehungen als Kanten dargestellt werden. Physikalische Netzwerke wie etwa Computernetze oder Transportnetze - wie beispielsweise das U-Bahnliniennetz einer Stadt - lassen sich ebenfalls als Graph auffassen. Um Graphen und die damit modellierten Daten gut erfassen zu können benötigen wir eine Visualisierung. Das Graphenzeichnen befasst sich mit dem Entwickeln von Algorithmen zur Visualisierung von Graphen. Diese Dissertation beschäftigt sich insbesondere mit dem Einsatz von Kreuzungen und Kurven beim Zeichnen von Graphen unter Nebenbedingungen (Constraints). Die in den untersuchten Problemen auftretenden Nebenbedingungen sorgen unter anderem dafür, dass die Lage eines Teils der Knoten - als feste Anforderung oder als Optimierungskriterium - vorgegeben ist. KW - Graphenzeichnen KW - Kreuzung KW - Kurve KW - Graph KW - graph drawing KW - crossing minimization KW - curves KW - labeling KW - metro map KW - Kreuzungsminimierung KW - Landkartenbeschriftung KW - U-Bahnlinienplan Y1 - 2014 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-98235 SN - 978-3-95826-002-3 (print) SN - 978-3-95826-003-0 (online) PB - Würzburg University Press ER - TY - JOUR A1 - Fischer, Norbert A1 - Hartelt, Alexander A1 - Puppe, Frank T1 - Line-level layout recognition of historical documents with background knowledge JF - Algorithms N2 - Digitization and transcription of historic documents offer new research opportunities for humanists and are the topics of many edition projects. However, manual work is still required for the main phases of layout recognition and the subsequent optical character recognition (OCR) of early printed documents. This paper describes and evaluates how deep learning approaches recognize text lines and can be extended to layout recognition using background knowledge. The evaluation was performed on five corpora of early prints from the 15th and 16th Centuries, representing a variety of layout features. While the main text with standard layouts could be recognized in the correct reading order with a precision and recall of up to 99.9%, also complex layouts were recognized at a rate as high as 90% by using background knowledge, the full potential of which was revealed if many pages of the same source were transcribed. KW - layout recognition KW - background knowledge KW - historical document analysis KW - fully convolutional neural networks KW - baseline detection KW - text line detection Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-310938 SN - 1999-4893 VL - 16 IS - 3 ER - TY - JOUR A1 - Fisseler, Denis A1 - Müller, Gerfrid G. W. A1 - Weichert, Frank T1 - Web-Based scientific exploration and analysis of 3D scanned cuneiform datasets for collaborative research JF - Informatics N2 - The three-dimensional cuneiform script is one of the oldest known writing systems and a central object of research in Ancient Near Eastern Studies and Hittitology. An important step towards the understanding of the cuneiform script is the provision of opportunities and tools for joint analysis. This paper presents an approach that contributes to this challenge: a collaborative compatible web-based scientific exploration and analysis of 3D scanned cuneiform fragments. The WebGL -based concept incorporates methods for compressed web-based content delivery of large 3D datasets and high quality visualization. To maximize accessibility and to promote acceptance of 3D techniques in the field of Hittitology, the introduced concept is integrated into the Hethitologie-Portal Mainz, an established leading online research resource in the field of Hittitology, which until now exclusively included 2D content. The paper shows that increasing the availability of 3D scanned archaeological data through a web-based interface can provide significant scientific value while at the same time finding a trade-off between copyright induced restrictions and scientific usability. KW - cuneiform KW - 3D viewer KW - WebGL KW - Hittitology KW - 3D collation Y1 - 2017 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-197958 SN - 2227-9709 VL - 4 IS - 4 ER - TY - THES A1 - Fleszar, Krzysztof T1 - Network-Design Problems in Graphs and on the Plane T1 - Netzwerk-Design-Probleme in Graphen und auf der Ebene N2 - A network design problem defines an infinite set whose elements, called instances, describe relationships and network constraints. It asks for an algorithm that, given an instance of this set, designs a network that respects the given constraints and at the same time optimizes some given criterion. In my thesis, I develop algorithms whose solutions are optimum or close to an optimum value within some guaranteed bound. I also examine the computational complexity of these problems. Problems from two vast areas are considered: graphs and the Euclidean plane. In the Maximum Edge Disjoint Paths problem, we are given a graph and a subset of vertex pairs that are called terminal pairs. We are asked for a set of paths where the endpoints of each path form a terminal pair. The constraint is that any two paths share at most one inner vertex. The optimization criterion is to maximize the cardinality of the set. In the hard-capacitated k-Facility Location problem, we are given an integer k and a complete graph where the distances obey a given metric and where each node has two numerical values: a capacity and an opening cost. We are asked for a subset of k nodes, called facilities, and an assignment of all the nodes, called clients, to the facilities. The constraint is that the number of clients assigned to a facility cannot exceed the facility's capacity value. The optimization criterion is to minimize the total cost which consists of the total opening cost of the facilities and the total distance between the clients and the facilities they are assigned to. In the Stabbing problem, we are given a set of axis-aligned rectangles in the plane. We are asked for a set of horizontal line segments such that, for every rectangle, there is a line segment crossing its left and right edge. The optimization criterion is to minimize the total length of the line segments. In the k-Colored Non-Crossing Euclidean Steiner Forest problem, we are given an integer k and a finite set of points in the plane where each point has one of k colors. For every color, we are asked for a drawing that connects all the points of the same color. The constraint is that drawings of different colors are not allowed to cross each other. The optimization criterion is to minimize the total length of the drawings. In the Minimum Rectilinear Polygon for Given Angle Sequence problem, we are given an angle sequence of left (+90°) turns and right (-90°) turns. We are asked for an axis-parallel simple polygon where the angles of the vertices yield the given sequence when walking around the polygon in counter-clockwise manner. The optimization criteria considered are to minimize the perimeter, the area, and the size of the axis-parallel bounding box of the polygon. N2 - Ein Netzwerk-Design-Problem definiert eine unendliche Menge, deren Elemente, als Instanzen bezeichnet, Beziehungen und Beschränkungen in einem Netzwerk beschreiben. Die Lösung eines solchen Problems besteht aus einem Algorithmus, der auf die Eingabe einer beliebigen Instanz dieser Menge ein Netzwerk entwirft, welches die gegebenen Beschränkungen einhält und gleichzeitig ein gegebenes Kriterium optimiert. In meiner Dissertation habe ich Algorithmen entwickelt, deren Netzwerke stets optimal sind oder nachweisbar nahe am Optimum liegen. Zusätzlich habe ich die Berechnungskomplexität dieser Probleme untersucht. Dabei wurden Probleme aus zwei weiten Gebieten betrachtet: Graphen und der Euklidische Ebene. Im Maximum-Edge-Disjoint-Paths-Problem besteht die Eingabe aus einem Graphen und einer Teilmenge von Knotenpaaren, die wir mit Terminalpaare bezeichnen. Gesucht ist eine Menge von Pfaden, die Terminalpaare verbinden. Die Beschränkung ist, dass keine zwei Pfade einen gleichen inneren Knoten haben dürfen. Das Optimierungskriterium ist die Maximierung der Kardinalität dieser Menge. Im Hard-Capacitated-k-Facility-Location-Problem besteht die Eingabe aus einer Ganzzahl k und einem vollständigen Graphen, in welchem die Distanzen einer gegebenen Metrik unterliegen und in welchem jedem Knoten sowohl eine numerische Kapazität als auch ein Eröffnungskostenwert zugeschrieben ist. Gesucht ist eine Teilmenge von k Knoten, Facilities genannt, und eine Zuweisung aller Knoten, Clients genannt, zu den Facilities. Die Beschränkung ist, dass die Anzahl der Clients, die einer Facility zugewiesen sind, nicht deren Kapazität überschreiten darf. Das Optimierungskriterium ist die Minimierung der Gesamtkosten bestehend aus den Gesamteröffnungskosten der Facilities sowie der Gesamtdistanz zwischen den Clients und den ihnen zugewiesenen Facilities. Im Stabbing-Problem besteht die Eingabe aus einer Menge von achsenparallelen Rechtecken in der Ebene. Gesucht ist eine Menge von horizontalen Geradenstücken mit der Randbedingung, dass die linke und rechte Seite eines jeden Rechtecks von einem Geradenstück verbunden ist. Das Optimierungskriterium ist die Minimierung der Gesamtlänge aller Geradenstücke. Im k-Colored-Non-Crossing-Euclidean-Steiner-Forest-Problem besteht die Eingabe aus einer Ganzzahl k und einer endlichen Menge von Punkten in der Ebene, wobei jeder Punkt in einer von k Farben gefärbt ist. Gesucht ist für jede Farbe eine Zeichnung, in welcher alle Punkte der Farbe verbunden sind. Die Beschränkung ist, dass Zeichnungen verschiedener Farben sich nicht kreuzen dürfen. Das Optimierungskriterium ist die Minimierung des Gesamtintenverbrauchs, das heißt, der Gesamtlänge der Zeichnungen. Im Minimum-Rectilinear-Polygon-for-Given-Angle-Sequence-Problem besteht die Eingabe aus einer Folge von Links- (+90°) und Rechtsabbiegungen (-90°). Gesucht ist ein achsenparalleles Polygon dessen Eckpunkte die gegebene Folge ergeben, wenn man das Polygon gegen den Uhrzeigersinn entlangläuft. Die Optimierungskriterien sind die Minimierung des Umfangs und der inneren Fläche des Polygons sowie der Größe des notwendigen Zeichenblattes, d.h., des kleinsten Rechteckes, das das Polygon einschließt. N2 - Given points in the plane, connect them using minimum ink. Though the task seems simple, it turns out to be very time consuming. In fact, scientists believe that computers cannot efficiently solve it. So, do we have to resign? This book examines such NP-hard network-design problems, from connectivity problems in graphs to polygonal drawing problems on the plane. First, we observe why it is so hard to optimally solve these problems. Then, we go over to attack them anyway. We develop fast algorithms that find approximate solutions that are very close to the optimal ones. Hence, connecting points with slightly more ink is not hard. KW - Euklidische Ebene KW - Algorithmus KW - Komplexität KW - NP-schweres Problem KW - Graph KW - approximation algorithm KW - hardness KW - optimization KW - graphs KW - network KW - Optimierungsproblem KW - Approximationsalgorithmus KW - complexity KW - Euclidean plane Y1 - 2018 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-154904 SN - 978-3-95826-076-4 (Print) SN - 978-3-95826-077-1 (Online) N1 - Parallel erschienen als Druckausgabe in Würzburg University Press, ISBN 978-3-95826-076-4, 28,90 EUR. PB - Würzburg University Press CY - Würzburg ET - 1. Auflage ER - TY - THES A1 - Freiberg, Martina T1 - UI-, User-, & Usability-Oriented Engineering of Participative Knowledge-Based Systems T1 - UI-, Benutzer-, & Usability-orientierte Entwicklung partizipativer Wissensbasierter Systeme N2 - Knowledge-based systems (KBS) face an ever-increasing interest in various disciplines and contexts. Yet, the former aim to construct the ’perfect intelligent software’ continuously shifts to user-centered, participative solutions. Such systems enable users to contribute their personal knowledge to the problem solving process for increased efficiency and an ameliorated user experience. More precisely, we define non-functional key requirements of participative KBS as: Transparency (encompassing KBS status mediation), configurability (user adaptability, degree of user control/exploration), quality of the KB and UI, and evolvability (enabling the KBS to grow mature with their users). Many of those requirements depend on the respective target users, thus calling for a more user-centered development. Often, also highly expertise domains are targeted — inducing highly complex KBs — which requires a more careful and considerate UI/interaction design. Still, current KBS engineering (KBSE) approaches mostly focus on knowledge acquisition (KA) This often leads to non-optimal, little reusable, and non/little evaluated KBS front-end solutions. In this thesis we propose a more encompassing KBSE approach. Due to the strong mutual influences between KB and UI, we suggest a novel form of intertwined UI and KB development. We base the approach on three core components for encompassing KBSE: (1) Extensible prototyping, a tailored form of evolutionary prototyping; this builds on mature UI prototypes and offers two extension steps for the anytime creation of core KBS prototypes (KB + core UI) and fully productive KBS (core KBS prototype + common framing functionality). (2) KBS UI patterns, that define reusable solutions for the core KBS UI/interaction; we provide a basic collection of such patterns in this work. (3) Suitable usability instruments for the assessment of the KBS artifacts. Therewith, we do not strive for ’yet another’ self-contained KBS engineering methodology. Rather, we motivate to extend existing approaches by the proposed key components. We demonstrate this based on an agile KBSE model. For practical support, we introduce the tailored KBSE tool ProKEt. ProKEt offers a basic selection of KBS core UI patterns and corresponding configuration options out of the box; their further adaption/extension is possible on various levels of expertise. For practical usability support, ProKEt offers facilities for quantitative and qualitative data collection. ProKEt explicitly fosters the suggested, intertwined development of UI and KB. For seamlessly integrating KA activities, it provides extension points for two selected external KA tools: For KnowOF, a standard office based KA environment. And for KnowWE, a semantic wiki for collaborative KA. Therewith, ProKEt offers powerful support for encompassing, user-centered KBSE. Finally, based on the approach and the tool, we also developed a novel KBS type: Clarification KBS as a mashup of consultation and justification KBS modules. Those denote a specifically suitable realization for participative KBS in highly expertise contexts and consequently require a specific design. In this thesis, apart from more common UI solutions, we particularly also introduce KBS UI patterns especially tailored towards Clarification KBS. N2 - Das Interesse an wissensbasierten Systemen (WBS) in verschiedensten Fachdisziplinen und Anwendungskontexten wächst nach wie vor stetig. Das frühere Ziel — intelligente Software als Expertenersatz — verschiebt sich dabei allerdings kontinuierlich in Richtung partizipativer, nutzerzentrierter Anwendungen. Solche Systeme erlauben dem Benutzer, das vorhandene persönliche Hintergrundwissen in den Problemlösungsprozess mit einzubringen um die Effizienz des Systems zu steigern und die User Experience zu verbessern. Konkret definieren wir für partizipative WBS die folgenden, nichtfunktionalen Anforderungen: Transparenz (umfassende Vermittlung des Systemstatus), Konfigurierbarkeit (Anpassbarkeit an verschiedene Benutzer und Grad der Benutzerkontrolle und Explorationsmöglichkeit), Qualität sowohl der Wissensbasis als auch der Benutzeroberfläche und Fortentwickelbarkeit (Fähigkeit des WBS analog zu den Kenntnissen seiner Nutzer zu reifen). Viele dieser Anforderungen hängen stark von den jeweiligen Nutzern ab. Im Umkehrschluss erfordert dies eine nutzerzentriertere Entwicklung solcher Systeme. Die häufig sehr fachspezifischen Zieldomänen haben meist entsprechend komplexe Wissensbasen zur Folge. Dies verlangt erst Recht nach einem wohlüberlegten, durchdachten UI- und Inkteraktionsdesign. Dem zum Trotz fokussieren aktuelle WBS Entwicklungsansätze jedoch nach wie vor auf der Wissensformalisierung. Mit der Folge, dass oft keine optimalen, schlecht wiederverwendbare und nur teilweise (oder gar nicht) evaluierte WBS UI/Interaktionslösungen entstehen. Die vorliegende Dissertation schlägt einen allumfassenderen WBS Entwicklungsansatz vor. Unter Berücksichtigung der starken, wechselseitigen Beeinflussung von Wissensbasis und UI ist dieser geprägt durch eine starke Verzahnung von Wissensbasis- und UI-Entwicklung. Der Ansatz stützt sich auf drei Kernkomponenten für allumfassende Entwicklung wissensbasierter Systeme: (1) Extensible Prototyping, eine adaptierte Form des evolutionären Prototyping. Extensible Prototyping basiert auf hochentwickelten UI Prototypen und definiert zwei Erweiterungsschritte um jederzeit WBS-Kernprototypen (Wissensbasis und Kern-UI) beziehungsweise voll funktionale wissensbasierte Anwendungen (WBS Kernprototyp und Rahmenfunktionalität) zu erstellen. (2) WBS UI Patterns. Diese Patterns, oder Muster, definieren wiederverwendbare Lösungen für die Kern-UI und -Inkteraktion. In dieser Arbeit stellen wir eine Sammlung grundlegender WBS UI Patterns vor. (3) Passende Usability Techniken die sich speziell für die Evaluation von WBS Software eignen. Insgesamt streben wir keine weitere, in sich geschlossene WBS Entwicklungsmethodologie an. Vielmehr motivieren wir, existierende, Wissensformalisierungs-lastige Ansätze um die vorgeschlagenen Kernkomponenten zu erweitern. Wir demonstrieren das am agilen Prozessmodell für wissensbasierte Systeme. Für die praktische Umsetzung des vorgestellten Ansatzes stellen wir außerdem das spezialisierte WBS Prototyping- und Softwareentwicklungswerkzeug ProKEt vor. ProKEt unterstützt eine Auswahl der interessantesten WBS UI Patterns sowie zugehöriger Konfigurationsoptionen. Deren weitere Anpassung beziehungsweise Erweiterung ist auf verschiedenen Expertise-Leveln möglich. Um ebenso die Anwendung von Usability Techniken zu unterstützen, bietet ProKEt weiterhin Funktionalität für die quantitative und qualitative Datensammlung. Auch baut ProKEt bewusst auf die strikt verzahnte Entwicklung von UI- und Wissensbasis. Für die einfache und nahtlose Integration von Wissensformalisierung in den Gesamtprozess unterstützt ProKEt zwei externe Wissensformalisierungs-Werkzeuge: KnowOF, eine Wissensformalisierungsumgebung welche standartisierte Office Dokumente nutzt. Und KnowWE, ein semantisches Wiki für die kollaborative Wissensformalisierung im Web. Damit ist ProKEt ein mächtiges Werkzeug für umfassende, nutzerzentrierte WBS Entwicklung. Mithilfe des Entwicklungsansatzes und des Werkzeugs ProKEt haben wir weiterhin einen neuartigen WBS Typ entwickelt: Wissensbasierte Klärungssysteme, im Wesentlichen ein Mashup aus Beratungs-, Erklärungs- und Rechtfertigungskomponente. Diese Systeme stellen eine angepasste Realisierung von partizipativen WBS für höchst fachliche Kontexte dar und verlangten entsprechend nach einem sehr speziellen Design. In der vorliegenden Arbeit stellen wir daher neben allgemeinen WBS UI Patterns auch einige spezialisierte Varianten für wissensbasierte Klärungssysteme vor. KW - Wissensbasiertes System KW - Knowledge-based Systems Engineering KW - Expert System KW - Usability KW - UI and Interaction Design KW - User Participation KW - Expertensystem Y1 - 2015 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-106072 SN - 978-3-95826-012-2 (print) SN - 978-3-95826-013-9 (online) PB - Würzburg University Press ER - TY - RPRT A1 - Funda, Christoph A1 - Konheiser, Tobias A1 - German, Reinhard A1 - Hielscher, Kai-Steffen T1 - How to Model and Predict the Scalability of a Hardware-In-The-Loop Test Bench for Data Re-Injection? T2 - KuVS Fachgespräch - Würzburg Workshop on Modeling, Analysis and Simulation of Next-Generation Communication Networks 2023 (WueWoWAS’23) N2 - This paper describes a novel application of an empirical network calculus model based on measurements of a hardware-in-the-loop (HIL) test system. The aim is to predict the performance of a HIL test bench for open-loop re-injection in the context of scalability. HIL test benches are distributed computer systems including software, hardware, and networking devices. They are used to validate complex technical systems, but have not yet been system under study themselves. Our approach is to use measurements from the HIL system to create an empirical model for arrival and service curves. We predict the performance and design the previously unknown parameters of the HIL simulator with network calculus (NC), namely the buffer sizes and the minimum needed pre-buffer time for the playback buffer. We furthermore show, that it is possible to estimate the CPU load from arrival and service-curves based on the utilization theorem, and hence estimate the scalability of the HIL system in the context of the number of sensor streams. KW - hardware-in-the-loop simulation KW - computer performance evaluation KW - network calculus KW - scalability evaluation Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-322150 ER - TY - RPRT A1 - Funda, Christoph A1 - Marín García, Pablo A1 - German, Reinhard A1 - Hielscher, Kai-Steffen T1 - Online Algorithm for Arrival & Service Curve Estimation T2 - KuVS Fachgespräch - Würzburg Workshop on Modeling, Analysis and Simulation of Next-Generation Communication Networks 2023 (WueWoWAS’23) N2 - This paper presents a novel concept to extend state-of-the-art buffer monitoring with additional measures to estimate service-curves. The online algorithm for service-curve estimation replaces the state-of-the-art timestamp logging, as we expect it to overcome the main disadvantages of generating a huge amount of data and using a lot of CPU resources to store the data to a file during operation. We prove the accuracy of the online-algorithm offline with timestamp data and compare the derived bounds to the measured delay and backlog. We also do a proof-of- concept of the online-algorithm, implement it in LabVIEW and compare its performance to the timestamp logging by CPU load and data-size of the log-file. However, the implementation is still work-in-progress. KW - hardware-in-the-loop streaming system KW - network calculus KW - service-curve estimation KW - performance monitoring Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-322112 ER - TY - JOUR A1 - Gageik, Nils A1 - Strohmeier, Michael A1 - Montenegro, Sergio T1 - Waypoint flight parameter comparison of an autonomous UAV JF - International Journal of Artificial Intelligence & Applications (IJAIA) N2 - The present paper compares the effect of different waypoint parameters on the flight performance of a special autonomous indoor UAV (unmanned aerial vehicle) fusing ultrasonic, inertial, pressure and optical sensors for 3D positioning and controlling. The investigated parameters are the acceptance threshold for reaching a waypoint as well as the maximal waypoint step size or block size. The effect of these parameters on the flight time and accuracy of the flight path is investigated. Therefore the paper addresses how the acceptance threshold and step size influence the speed and accuracy of the autonomous flight and thus influence the performance of the presented autonomous quadrocopter under real indoor navigation circumstances. Furthermore the paper demonstrates a drawback of the standard potential field method for navigation of such autonomous quadrocopters and points to an improvement. KW - autonomous UAV KW - Quadrocopter KW - Quadrotor KW - waypoint parameter KW - navigation Y1 - 2013 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-96833 ER - TY - JOUR A1 - Gageik, Nils A1 - Strohmeier, Michael A1 - Montenegro, Sergio T1 - An Autonomous UAV with an Optical Flow Sensor for Positioning and Navigation JF - International Journal of Advanced Robotic Systems N2 - A procedure to control all six DOF (degrees of freedom) of a UAV (unmanned aerial vehicle) without an external reference system and to enable fully autonomous flight is presented here. For 2D positioning the principle of optical flow is used. Together with the output of height estimation, fusing ultrasonic, infrared and inertial and pressure sensor data, the 3D position of the UAV can be computed, controlled and steered. All data processing is done on the UAV. An external computer with a pathway planning interface is for commanding purposes only. The presented system is part of the AQopterI8 project, which aims to develop an autonomous flying quadrocopter for indoor application. The focus of this paper is 2D positioning using an optical flow sensor. As a result of the performed evaluation, it can be concluded that for position hold, the standard deviation of the position error is 10cm and after landing the position error is about 30cm. KW - Autonomous UAV KW - Quadrocopter KW - Quadrotor KW - Optical Flow KW - positioning KW - navigation Y1 - 2013 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-96368 ER - TY - RPRT A1 - Gallenmüller, Sebastian A1 - Scholz, Dominik A1 - Stubbe, Henning A1 - Hauser, Eric A1 - Carle, Georg T1 - Reproducible by Design: Network Experiments with pos T2 - Würzburg Workshop on Next-Generation Communication Networks (WueWoWas'22) N2 - In scientific research, the independent reproduction of experiments is the source of trust. Detailed documentation is required to enable experiment reproduction. Reproducibility awards were created to honor the increased documentation effort. In this work, we propose a novel approach toward reproducible research—a structured experimental workflow that allows the creation of reproducible experiments without requiring additional efforts of the researcher. Moreover, we present our own testbed and toolchain, namely, plain orchestrating service (pos), which enables the creation of such experimental workflows. The experiment is documented by our proposed, fully scripted experiment structure. In addition, pos provides scripts enabling the automation of the bundling and release of all experimental artifacts. We provide an interactive environment where pos experiments can be executed and reproduced, available at https://gallenmu.github.io/single-server-experiment. KW - Datennetz KW - Reproducibility KW - Testbed KW - Network Experiments KW - plain orchestrating service KW - pos Y1 - 2022 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-280834 ER - TY - THES A1 - Geißler, Stefan T1 - Performance Evaluation of Next-Generation Data Plane Architectures and their Components T1 - Leistungsbewertung von Data Plane Architekturen der Nächsten Generation sowie ihrer Einzelkomponenten N2 - In this doctoral thesis we cover the performance evaluation of next generation data plane architectures, comprised of complex software as well as programmable hardware components that allow fine granular configuration. In the scope of the thesis we propose mechanisms to monitor the performance of singular components and model key performance indicators of software based packet processing solutions. We present novel approaches towards network abstraction that allow the integration of heterogeneous data plane technologies into a singular network while maintaining total transparency between control and data plane. Finally, we investigate a full, complex system consisting of multiple software-based solutions and perform a detailed performance analysis. We employ simulative approaches to investigate overload control mechanisms that allow efficient operation under adversary conditions. The contributions of this work build the foundation for future research in the areas of network softwarization and network function virtualization. N2 - Diese Doktorarbeit behandelt die Leistungsbewertung von Data Plane Architekturen der nächsten Generation, die aus komplexen Softwarelösungen sowie programmierbaren Hardwarekomponenten bestehen. Hierbei werden Mechanismen entwickelt, die es ermöglichen, die Leistungsfähigkeit einzelner Komponenten zu messen und zentrale Leistungsindikatoren softwarebasierter Systeme zur Verarbeitung von Datenpaketen zu modellieren. Es werden neuartige Ansätze zur Netzabstraktion entworfen, die eine vollständig transparente Integration heterogener Technologien im selben Netz ermöglichen. Schließlich wird eine umfassende Leistungsbewertung eines komplexen Systems, das aus einer Vielzahl softwarebasierter Netzfunktionen besteht, durchgeführt. Anhand simulativer Modelle werden Überlastkontrollmechanismen entwickelt, die es dem System erlauben auch unter Überlast effizient zu arbeiten. Die Beiträge dieser Arbeit bilden die Grundlage weiterer Forschungen im Bereich der Softwarisierung von Netzen sowie der Virtualisierung von Netzfunktionen. T3 - Würzburger Beiträge zur Leistungsbewertung Verteilter Systeme - 02/21 KW - Leistungsbewertung KW - Simulation KW - Zeitdiskretes System KW - Implementierung KW - performance evaluation KW - simulation KW - discrete-time analysis KW - network softwarization KW - mobile networks Y1 - 2022 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-260157 SN - 1432-8801 ER - TY - THES A1 - Glaßer, Christian T1 - Forbidden-Patterns and Word Extensions for Concatenation Hierarchies T1 - Verbotsmuster und Worterweiterungen für Konkatenationshierarchien N2 - Starfree regular languages can be build up from alphabet letters by using only Boolean operations and concatenation. The complexity of these languages can be measured with the so-called dot-depth. This measure leads to concatenation hierarchies like the dot-depth hierarchy (DDH) and the closely related Straubing-Thérien hierarchy (STH). The question whether the single levels of these hierarchies are decidable is still open and is known as the dot-depth problem. In this thesis we prove/reprove the decidability of some lower levels of both hierarchies. More precisely, we characterize these levels in terms of patterns in finite automata (subgraphs in the transition graph) that are not allowed. Therefore, such characterizations are called forbidden-pattern characterizations. The main results of the thesis are as follows: forbidden-pattern characterization for level 3/2 of the DDH (this implies the decidability of this level) decidability of the Boolean hierarchy over level 1/2 of the DDH definition of decidable hierarchies having close relations to the DDH and STH Moreover, we prove/reprove the decidability of the levels 1/2 and 3/2 of both hierarchies in terms of forbidden-pattern characterizations. We show the decidability of the Boolean hierarchies over level 1/2 of the DDH and over level 1/2 of the STH. A technique which uses word extensions plays the central role in the proofs of these results. With this technique it is possible to treat the levels 1/2 and 3/2 of both hierarchies in a uniform way. Furthermore, it can be used to prove the decidability of the mentioned Boolean hierarchies. Among other things we provide a combinatorial tool that allows to partition words of arbitrary length into factors of bounded length such that every second factor u leads to a loop with label u in a given finite automaton. N2 - Sternfreie reguläre Sprachen können aus Buchstaben unter Verwendung Boolescher Operationen und Konkatenation aufgebaut werden. Die Komplexität solcher Sprachen lässt sich durch die sogenannte "Dot-Depth" messen. Dieses Maß führt zu Konkatenationshierarchien wie der Dot-Depth-Hierachie (DDH) und der Straubing-Thérien-Hierarchie (STH). Die Frage nach der Entscheidbarkeit der einzelnen Stufen dieser Hierarchien ist als (immer noch offenes) Dot-Depth-Problem bekannt. In dieser Arbeit beweisen wir die Entscheidbarkeit einiger unterer Stufen beider Hierarchien. Genauer gesagt charakterisieren wir diese Stufen durch das Verbot von bestimmten Mustern in endlichen Automaten. Solche Charakterisierungen werden Verbotsmustercharakterisierungen genannt. Die Hauptresultate der Arbeit lassen sich wie folgt zusammenfassen: Verbotsmustercharakterisierung der Stufe 3/2 der DDH (dies hat die Entscheidbarkeit dieser Stufe zur Folge) Entscheidbarkeit der Booleschen Hierarchie über der Stufe 1/2 der DDH Definition von entscheidbaren Hierarchien mit engen Verbindungen zur DDH und STH Darüber hinaus beweisen wir die Entscheidbarkeit der Stufen 1/2 und 3/2 beider Hierarchien (wieder mittels Verbotsmustercharakterisierungen) und die der Booleschen Hierarchien über den Stufen 1/2 der DDH bzw. STH. Dabei stützen sich die Beweise größtenteils auf eine Technik, die von Eigenschaften bestimmter Worterweiterungen Gebrauch macht. Diese Technik erlaubt eine einheitliche Vorgehensweise bei der Untersuchung der Stufen 1/2 und 3/2 beider Hierarchien. Außerdem wird sie in den Beweisen der Entscheidbarkeit der genannten Booleschen Hierarchien verwendet. Unter anderem wird ein kombinatorisches Hilfsmittel zur Verfügung gestellt, das es erlaubt, Wörter beliebiger Länge in Faktoren beschränkter Länge zu zerlegen, so dass jeder zweite Faktor u zu einer u-Schleife in einem gegebenen endlichen Automaten führt. KW - Automatentheorie KW - Formale Sprache KW - Entscheidbarkeit KW - Reguläre Sprache KW - Berechenbarkeit KW - Theoretische Informatik KW - reguläre Sprachen KW - endliche Automaten KW - Dot-Depth Problem KW - Entscheidbarkeit KW - Verbotsmuster KW - Worterweiterungen KW - Theoretical Computer Science KW - regular languages KW - finite automata KW - dot-depth problem KW - decidability KW - forbidden patterns KW - word extensions Y1 - 2001 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-1179153 ER - TY - JOUR A1 - Glémarec, Yann A1 - Lugrin, Jean-Luc A1 - Bosser, Anne-Gwenn A1 - Buche, Cédric A1 - Latoschik, Marc Erich T1 - Controlling the stage: a high-level control system for virtual audiences in Virtual Reality JF - Frontiers in Virtual Reality N2 - This article presents a novel method for controlling a virtual audience system (VAS) in Virtual Reality (VR) application, called STAGE, which has been originally designed for supervised public speaking training in university seminars dedicated to the preparation and delivery of scientific talks. We are interested in creating pedagogical narratives: narratives encompass affective phenomenon and rather than organizing events changing the course of a training scenario, pedagogical plans using our system focus on organizing the affects it arouses for the trainees. Efficiently controlling a virtual audience towards a specific training objective while evaluating the speaker’s performance presents a challenge for a seminar instructor: the high level of cognitive and physical demands required to be able to control the virtual audience, whilst evaluating speaker’s performance, adjusting and allowing it to quickly react to the user’s behaviors and interactions. It is indeed a critical limitation of a number of existing systems that they rely on a Wizard of Oz approach, where the tutor drives the audience in reaction to the user’s performance. We address this problem by integrating with a VAS a high-level control component for tutors, which allows using predefined audience behavior rules, defining custom ones, as well as intervening during run-time for finer control of the unfolding of the pedagogical plan. At its core, this component offers a tool to program, select, modify and monitor interactive training narratives using a high-level representation. The STAGE offers the following features: i) a high-level API to program pedagogical narratives focusing on a specific public speaking situation and training objectives, ii) an interactive visualization interface iii) computation and visualization of user metrics, iv) a semi-autonomous virtual audience composed of virtual spectators with automatic reactions to the speaker and surrounding spectators while following the pedagogical plan V) and the possibility for the instructor to embody a virtual spectator to ask questions or guide the speaker from within the Virtual Environment. We present here the design, and implementation of the tutoring system and its integration in STAGE, and discuss its reception by end-users. KW - virtual reality KW - virtual agent KW - behavior perception KW - public speaking KW - education Y1 - 2022 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-284601 SN - 2673-4192 VL - 3 ER - TY - JOUR A1 - Glémarec, Yann A1 - Lugrin, Jean-Luc A1 - Bosser, Anne-Gwenn A1 - Collins Jackson, Aryana A1 - Buche, Cédric A1 - Latoschik, Marc Erich T1 - Indifferent or Enthusiastic? Virtual Audiences Animation and Perception in Virtual Reality JF - Frontiers in Virtual Reality N2 - In this paper, we present a virtual audience simulation system for Virtual Reality (VR). The system implements an audience perception model controlling the nonverbal behaviors of virtual spectators, such as facial expressions or postures. Groups of virtual spectators are animated by a set of nonverbal behavior rules representing a particular audience attitude (e.g., indifferent or enthusiastic). Each rule specifies a nonverbal behavior category: posture, head movement, facial expression and gaze direction as well as three parameters: type, frequency and proportion. In a first user-study, we asked participants to pretend to be a speaker in VR and then create sets of nonverbal behaviour parameters to simulate different attitudes. Participants manipulated the nonverbal behaviours of single virtual spectator to match a specific levels of engagement and opinion toward them. In a second user-study, we used these parameters to design different types of virtual audiences with our nonverbal behavior rules and evaluated their perceptions. Our results demonstrate our system’s ability to create virtual audiences with three types of different perceived attitudes: indifferent, critical, enthusiastic. The analysis of the results also lead to a set of recommendations and guidelines regarding attitudes and expressions for future design of audiences for VR therapy and training applications. KW - virtual reality KW - perception KW - nonverbal behavior KW - interaction KW - virtual agent KW - virtual audience Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-259328 VL - 2 ER - TY - JOUR A1 - Greubel, André A1 - Andres, Daniela A1 - Hennecke, Martin T1 - Analyzing reporting on ransomware incidents: a case study JF - Social Sciences N2 - Knowledge about ransomware is important for protecting sensitive data and for participating in public debates about suitable regulation regarding its security. However, as of now, this topic has received little to no attention in most school curricula. As such, it is desirable to analyze what citizens can learn about this topic outside of formal education, e.g., from news articles. This analysis is both relevant to analyzing the public discourse about ransomware, as well as to identify what aspects of this topic should be included in the limited time available for this topic in formal education. Thus, this paper was motivated both by educational and media research. The central goal is to explore how the media reports on this topic and, additionally, to identify potential misconceptions that could stem from this reporting. To do so, we conducted an exploratory case study into the reporting of 109 media articles regarding a high-impact ransomware event: the shutdown of the Colonial Pipeline (located in the east of the USA). We analyzed how the articles introduced central terminology, what details were provided, what details were not, and what (mis-)conceptions readers might receive from them. Our results show that an introduction of the terminology and technical concepts of security is insufficient for a complete understanding of the incident. Most importantly, the articles may lead to four misconceptions about ransomware that are likely to lead to misleading conclusions about the responsibility for the incident and possible political and technical options to prevent such attacks in the future. KW - media analysis KW - informal education KW - IT security KW - ransomware KW - misconceptions Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-313746 SN - 2076-0760 VL - 12 IS - 5 ER - TY - RPRT A1 - Grigorjew, Alexej A1 - Diederich, Philip A1 - Hoßfeld, Tobias A1 - Kellerer, Wolfgang T1 - Affordable Measurement Setups for Networking Device Latency with Sub-Microsecond Accuracy T2 - Würzburg Workshop on Next-Generation Communication Networks (WueWoWas'22) N2 - This document presents a networking latency measurement setup that focuses on affordability and universal applicability, and can provide sub-microsecond accuracy. It explains the prerequisites, hardware choices, and considerations to respect during measurement. In addition, it discusses the necessity for exhaustive latency measurements when dealing with high availability and low latency requirements. Preliminary results show that the accuracy is within ±0.02 μs when used with the Intel I350-T2 network adapter. KW - Datennetz KW - latency Y1 - 2022 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-280751 ER - TY - RPRT A1 - Grigorjew, Alexej A1 - Schumann, Lukas Kilian A1 - Diederich, Philip A1 - Hoßfeld, Tobias A1 - Kellerer, Wolfgang T1 - Understanding the Performance of Different Packet Reception and Timestamping Methods in Linux T2 - KuVS Fachgespräch - Würzburg Workshop on Modeling, Analysis and Simulation of Next-Generation Communication Networks 2023 (WueWoWAS’23) N2 - This document briefly presents some renowned packet reception techniques for network packets in Linux systems. Further, it compares their performance when measuring packet timestamps with respect to throughput and accuracy. Both software and hardware timestamps are compared, and various parameters are examined, including frame size, link speed, network interface card, and CPU load. The results indicate that hardware timestamping offers significantly better accuracy with no downsides, and that packet reception techniques that avoid system calls offer superior measurement throughput. KW - packet reception method KW - timestamping method KW - Linux Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-322064 ER - TY - JOUR A1 - Grohmann, Johannes A1 - Herbst, Nikolas A1 - Chalbani, Avi A1 - Arian, Yair A1 - Peretz, Noam A1 - Kounev, Samuel T1 - A Taxonomy of Techniques for SLO Failure Prediction in Software Systems JF - Computers N2 - Failure prediction is an important aspect of self-aware computing systems. Therefore, a multitude of different approaches has been proposed in the literature over the past few years. In this work, we propose a taxonomy for organizing works focusing on the prediction of Service Level Objective (SLO) failures. Our taxonomy classifies related work along the dimensions of the prediction target (e.g., anomaly detection, performance prediction, or failure prediction), the time horizon (e.g., detection or prediction, online or offline application), and the applied modeling type (e.g., time series forecasting, machine learning, or queueing theory). The classification is derived based on a systematic mapping of relevant papers in the area. Additionally, we give an overview of different techniques in each sub-group and address remaining challenges in order to guide future research. KW - taxonomy KW - survey KW - failure prediction KW - anomaly prediction KW - anomaly detection KW - self-aware computing KW - self-adaptive systems KW - performance prediction Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-200594 SN - 2073-431X VL - 9 IS - 1 ER - TY - RPRT A1 - Großmann, Marcel A1 - Homeyer, Tobias T1 - Emulation of Multipath Transmissions in P4 Networks with Kathará T2 - KuVS Fachgespräch - Würzburg Workshop on Modeling, Analysis and Simulation of Next-Generation Communication Networks 2023 (WueWoWAS’23) N2 - Packets sent over a network can either get lost or reach their destination. Protocols like TCP try to solve this problem by resending the lost packets. However, retransmissions consume a lot of time and are cumbersome for the transmission of critical data. Multipath solutions are quite common to address this reliability issue and are available on almost every layer of the ISO/OSI model. We propose a solution based on a P4 network to duplicate packets in order to send them to their destination via multiple routes. The last network hop ensures that only a single copy of the traffic is further forwarded to its destination by adopting a concept similar to Bloom filters. Besides, if fast delivery is requested we provide a P4 prototype, which randomly forwards the packets over different transmission paths. For reproducibility, we implement our approach in a container-based network emulation system called Kathará. KW - P4 KW - multipath KW - emulation KW - Kathará Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-322095 ER - TY - RPRT A1 - Großmann, Marcel A1 - Le, Duy Thanh T1 - Visualization of Network Emulation Enabled by Kathará T2 - KuVS Fachgespräch - Würzburg Workshop on Modeling, Analysis and Simulation of Next-Generation Communication Networks 2023 (WueWoWAS’23) N2 - In network research, reproducibility of experiments is not always easy to achieve. Infrastructures are cumbersome to set up or are not available due to vendor-specific devices. Emulators try to overcome those issues to a given extent and are available in different service models. Unfortunately, the usability of emulators requires time-consuming efforts and a deep understanding of their functionality. At first, we analyze to which extent currently available open-source emulators support network configurations and how user-friendly they are. With these insights, we describe, how an ease-to-use emulator is implemented and may run as a Network Emulator as a Service (NEaaS). Therefore, virtualization plays a major role in order to deploy a NEaaS based on Kathará. KW - Network Emulator KW - Visualized Kathará KW - Containerization Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-322189 ER - TY - JOUR A1 - Gupta, Shishir K. A1 - Minocha, Rashmi A1 - Thapa, Prithivi Jung A1 - Srivastava, Mugdha A1 - Dandekar, Thomas T1 - Role of the pangolin in origin of SARS-CoV-2: an evolutionary perspective JF - International Journal of Molecular Sciences N2 - After the recent emergence of SARS-CoV-2 infection, unanswered questions remain related to its evolutionary history, path of transmission or divergence and role of recombination. There is emerging evidence on amino acid substitutions occurring in key residues of the receptor-binding domain of the spike glycoprotein in coronavirus isolates from bat and pangolins. In this article, we summarize our current knowledge on the origin of SARS-CoV-2. We also analyze the host ACE2-interacting residues of the receptor-binding domain of spike glycoprotein in SARS-CoV-2 isolates from bats, and compare it to pangolin SARS-CoV-2 isolates collected from Guangdong province (GD Pangolin-CoV) and Guangxi autonomous regions (GX Pangolin-CoV) of South China. Based on our comparative analysis, we support the view that the Guangdong Pangolins are the intermediate hosts that adapted the SARS-CoV-2 and represented a significant evolutionary link in the path of transmission of SARS-CoV-2 virus. We also discuss the role of intermediate hosts in the origin of Omicron. KW - COVID-19 KW - SARS-CoV-2 KW - origin KW - evolution KW - intermediate host KW - pangolin KW - mutation KW - recombination KW - adaptation KW - transmission KW - comparative sequence analysis Y1 - 2022 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-285995 SN - 1422-0067 VL - 23 IS - 16 ER - TY - JOUR A1 - Halbig, Andreas A1 - Latoschik, Marc Erich T1 - A systematic review of physiological measurements, factors, methods, and applications in virtual reality JF - Frontiers in Virtual Reality N2 - Measurements of physiological parameters provide an objective, often non-intrusive, and (at least semi-)automatic evaluation and utilization of user behavior. In addition, specific hardware devices of Virtual Reality (VR) often ship with built-in sensors, i.e. eye-tracking and movements sensors. Hence, the combination of physiological measurements and VR applications seems promising. Several approaches have investigated the applicability and benefits of this combination for various fields of applications. However, the range of possible application fields, coupled with potentially useful and beneficial physiological parameters, types of sensor, target variables and factors, and analysis approaches and techniques is manifold. This article provides a systematic overview and an extensive state-of-the-art review of the usage of physiological measurements in VR. We identified 1,119 works that make use of physiological measurements in VR. Within these, we identified 32 approaches that focus on the classification of characteristics of experience, common in VR applications. The first part of this review categorizes the 1,119 works by field of application, i.e. therapy, training, entertainment, and communication and interaction, as well as by the specific target factors and variables measured by the physiological parameters. An additional category summarizes general VR approaches applicable to all specific fields of application since they target typical VR qualities. In the second part of this review, we analyze the target factors and variables regarding the respective methods used for an automatic analysis and, potentially, classification. For example, we highlight which measurement setups have been proven to be sensitive enough to distinguish different levels of arousal, valence, anxiety, stress, or cognitive workload in the virtual realm. This work may prove useful for all researchers wanting to use physiological data in VR and who want to have a good overview of prior approaches taken, their benefits and potential drawbacks. KW - virtual reality KW - use cases KW - sesnsors KW - tools KW - biosignals KW - psychophyisology KW - HMD (Head-Mounted Display) KW - systematic review Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-260503 VL - 2 ER - TY - THES A1 - Hartmann, Matthias T1 - Optimization and Design of Network Architectures for Future Internet Routing T1 - Optimierung und Design von Netzwerkarchitekturen für zukünftiges Internet Routing N2 - At the center of the Internet’s protocol stack stands the Internet Protocol (IP) as a common denominator that enables all communication. To make routing efficient, resilient, and scalable, several aspects must be considered. Care must be taken that traffic is well balanced to make efficient use of the existing network resources, both in failure free operation and in failure scenarios. Finding the optimal routing in a network is an NP-complete problem. Therefore, routing optimization is usually performed using heuristics. This dissertation shows that a routing optimized with one objective function is often not good when looking at other objective functions. It can even be worse than unoptimized routing with respect to that objective function. After looking at failure-free routing and traffic distribution in different failure scenarios, the analysis is extended to include the loop-free alternate (LFA) IP fast reroute mechanism. Different application scenarios of LFAs are examined and a special focus is set on the fact that LFAs usually cannot protect all traffic in a network even against single link failures. Thus, the routing optimization for LFAs is targeted on both link utilization and failure coverage. Finally, the pre-congestion notification mechanism PCN for network admission control and overload protection is analyzed and optimized. Different design options for implementing the protocol are compared, before algorithms are developed for the calculation and optimization of protocol parameters and PCN-based routing. The second part of the thesis tackles a routing problem that can only be resolved on a global scale. The scalability of the Internet is at risk since a major and intensifying growth of the interdomain routing tables has been observed. Several protocols and architectures are analyzed that can be used to make interdomain routing more scalable. The most promising approach is the locator/identifier (Loc/ID) split architecture which separates routing from host identification. This way, changes in connectivity, mobility of end hosts, or traffic-engineering activities are hidden from the routing in the core of the Internet and the routing tables can be kept much smaller. All of the currently proposed Loc/ID split approaches have their downsides. In particular, the fact that most architectures use the ID for routing outside the Internet’s core is a poor design, which inhibits many of the possible features of a new routing architecture. To better understand the problems and to provide a solution for a scalable routing design that implements a true Loc/ID split, the new GLI-Split protocol is developed in this thesis, which provides separation of global and local routing and uses an ID that is independent from any routing decisions. Besides GLI-Split, several other new routing architectures implementing Loc/ID split have been proposed for the Internet. Most of them assume that a mapping system is queried for EID-to-RLOC mappings by an intermediate node at the border of an edge network. When the mapping system is queried by an intermediate node, packets are already on their way towards their destination, and therefore, the mapping system must be fast, scalable, secure, resilient, and should be able to relay packets without locators to nodes that can forward them to the correct destination. The dissertation develops a classification for all proposed mapping system architectures and shows their similarities and differences. Finally, the fast two-level mapping system FIRMS is developed. It includes security and resilience features as well as a relay service for initial packets of a flow when intermediate nodes encounter a cache miss for the EID-to-RLOC mapping. N2 - Daten durch das Internet werden heutzutage mit dem paketbasierten Internet Protokoll (IP) übertragen. Dezentralisierte Routingprotokolle innerhalb der einzelnen Netze sorgen für eine zielgerichtete Weiterleitung der einzelnen Pakete. Diese verteilten Protokolle können auch im Fehlerfall weiterarbeiten, benötigen aber mitunter sehr lange bis Daten wieder zuverlässig am Ziel ankommen. Um im Betrieb des Internets eine hohe Leistungsfähigkeit auch bei auftretenden Problemfällen zu gewährleisten, müssen die eingesetzten Protokolle optimal eingestellt werden. Zielfunktionen zur Optimierung paketbasierter Link-State Intradomain-Routingprotokolle: Ein wichtiger Faktor für die Performanz eines Netzes ist die Auswahl der administrativen Linkkosten, anhand derer die Weiterleitungsentscheidungen im Netz getroffen werden. Mit Hilfe von Modellen für Verkehrsaufkommen und für die darunterliegende Netzarchitektur kann mit geeigneten Optimierungsmethoden das Netz für verschiedene Szenarien bestmöglich eingestellt werden. Von besonderer Wichtigkeit ist hierbei die Auswahl der betrachteten Szenarien und Zielfunktionen für die Optimierung. Eine Routingkonfiguration die optimal für ein bestimmtes Ziel ist, kann beliebig schlecht für ein anderes Ziel sein. Zum Beispiel kann eine Konfiguration, die eine besonders hohe Fehlerabdeckung erreicht, zu einer sehr schlechten Verkehrsverteilung führen. Im Rahmen der Dissertation werden heuristische Optimierungen des Routings für verschiedene Protokolle und Anwendungsszenarien durchgeführt. Darüber hinaus wird eine Pareto-Optimierung implementiert, die gleichzeitig mehrere Ziele optimieren kann. Die Analysen werden zuerst für normales Routing im fehlerfreien Fall und für Fehlerszenarien durchgeführt. Daraufhin werden verschiedenste Anwendungsfälle des IP Fast-Reroute Mechanismus Loop-Free Alternates (LFA) betrachtet. Hier wird insbesondere auf die Problematik eingegangen, dass LFAs in Abhängigkeit vom eingestellten Routing in bestimmten Fehlerfällen nicht angewendet werden können. Beim Optimieren des Routings muss hier zusätzlich zur Lastverteilung auch noch die Maximierung der Fehlerabdeckung berücksichtigt werden. Schließlich folgt eine Untersuchung und Optimierung des Pre-Congestion Notification (PCN) Verfahren zur Netzzugangskontrolle und Überlaststeuerung. Hier werden verschiedene Architekturvarianten des Protokolls miteinander verglichen und Algorithmen zur Berechnung und Optimierung wichtiger Parameter des Protokolls entwickelt. Das Wachstum der Routingtabellen im Kern des Internets droht zu einem Skalierbarkeitsproblem zu werden. Ein Grund für diese Problematik ist die duale Funktion der IP-Adresse. Sie wird einerseits zur Identifikation eines Geräts benutzt und andererseits zur Weiterleitung der Daten zu diesem Gerät. Neue Mechanismen und Protokolle die eine Trennung zwischen den beiden Funktionalitäten der IP-Adresse ermöglichen sind potentielle Kandidaten für eine bessere Skalierbarkeit des Internetroutings und damit für die Erhaltung der Funktionalität des Internets. Design eines neuen Namens- und Routingprotokolls für skalierbares Interdomain-Routing: In der Dissertation werden grundlegende Eigenschaften die zu diesem Problem führen erörtert. Daraufhin werden vorhandene Ansätze zur Verbesserung der Skalierbarkeit des Internetroutings analysiert, und es werden Gemeinsamkeiten wie auch Schwachstellen identifiziert. Auf dieser Basis wird dann ein Protokoll entwickelt, das eine strikte Trennung zwischen Identifikationsadressen (IDs) und routebaren Locator-Adressen einhält. Das GLI-Split genannte Protokoll geht dabei über den einfachen Split von vorhandenen Architekturvorschlägen hinaus und führt eine weitere Adresse ein die nur für das lokale Routing innerhalb eines Endkunden-Netzes benutzt wird. Hierdurch wird die ID eines Endgeräts vollständig unabhängig vom Routing. Durch das GLI-Split Protokoll kann das globale Routing wieder skalierbar gemacht werden. Zusätzlich bietet es viele Vorteile für Netze die das Protokoll einführen, was als Anreiz nötig ist um den Einsatz eines neuen Protokolls zu motivieren. Solch ein Identifier/Locator Split Protokoll benötigt ein Mappingsystem um die Identifier der Endgeräte in routebare Locator-Adressen zu übersetzen. Im letzten Teil der Dissertation wird eine mehrstufige Mapping-Architektur namens FIRMS entwickelt. Über ein hierarchisches Verteilungssystem, das die Adressvergabestruktur der fünf Regionalen Internet Registrare (RIRs) und der darunterliegenden Lokalen Internet Registrare (LIRs) abbildet, werden die erforderlichen Zuordnungstabellen so verteilt, dass jederzeit schnell auf die benötigten Informationen zugegriffen werden kann. Hierbei wird auch besonders auf Sicherheitsaspekte geachtet. T3 - Würzburger Beiträge zur Leistungsbewertung Verteilter Systeme - 02/15 KW - Netzwerk KW - Routing KW - Optimierung KW - Netzwerkmanagement KW - Optimization KW - Future Internet Y1 - 2015 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-114165 SN - 1432-8801 ER - TY - RPRT A1 - Hasslinger, Gerhard A1 - Ntougias, Konstantinos A1 - Hasslinger, Frank A1 - Hohlfeld, Oliver T1 - Performance Analysis of Basic Web Caching Strategies (LFU, LRU, FIFO, ...) with Time-To-Live Data Validation T2 - KuVS Fachgespräch - Würzburg Workshop on Modeling, Analysis and Simulation of Next-Generation Communication Networks 2023 (WueWoWAS’23) N2 - Web caches often use a Time-to-live (TTL) limit to validate data consistency with web servers. We study the impact of TTL constraints on the hit ratio of basic strategies in caches of fixed size. We derive analytical results and confirm their accuracy in comparison to simulations. We propose a score-based caching method with awareness of the current TTL per data for improving the hit ratio close to the upper bound. KW - LRU KW - LFU KW - FIFO caching strategies KW - hit ratio analysis and simulation KW - TTL validation of data consistency Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-322048 ER - TY - THES A1 - Heck, Klaus T1 - Wireless LAN performance studies in the context of 4G networks N2 - Wireless communication is nothing new. The first data transmissions based on electromagnetic waves have been successfully performed at the end of the 19th century. However, it took almost another century until the technology was ripe for mass market. The first mobile communication systems based on the transmission of digital data were introduced in the late 1980s. Within just a couple of years they have caused a revolution in the way people communicate. The number of cellular phones started to outnumber the fixed telephone lines in many countries and is still rising. New technologies in 3G systems, such as UMTS, allow higher data rates and support various kinds of multimedia services. Nevertheless, the end of the road in wireless communication is far from being reached. In the near future, the Internet and cellular phone systems are expected to be integrated to a new form of wireless system. Bandwidth requirements for a rich set of wireless services, e.g.\ video telephony, video streaming, online gaming, will be easily met. The transmission of voice data will just be another IP based service. On the other hand, building such a system is by far not an easy task. The problems in the development of the UMTS system showed the high complexity of wireless systems with support for bandwidth-hungry, IP-based services. But the technological challenges are just one difficulty. Telecommunication systems are planned on a world-wide basis, such that standard bodies, governments, institutions, hardware vendors, and service providers have to find agreements and compromises on a number of different topics. In this work, we provide the reader with a discussion of many of the topics involved in the planning of a Wireless LAN system that is capable of being integrated into the 4th generation mobile networks (4G) that is being discussed nowadays. Therefore, it has to be able to cope with interactive voice and video traffic while still offering high data rates for best effort traffic. Let us assume a scenario where a huge office complex is completely covered with Wireless LAN access points. Different antenna systems are applied in order to reduce the number of access points that are needed on the one hand, while optimizing the coverage on the other. No additional infrastructure is implemented. Our goal is to evaluate whether the Wireless LAN technology is capable of dealing with the various demands of such a scenario. First, each single access point has to be capable of supporting best-effort and Quality of Service (QoS) demanding applications simultaneously. The IT infrastructure in our scenario consists solely of Wireless LAN, such that it has to allow users surfing the Web, while others are involved in voice calls or video conferences. Then, there is the problem of overlapping cells. Users attached to one access point produce interference for others. However, the QoS support has to be maintained, which is not an easy task. Finally, there are nomadic users, which roam from one Wireless LAN cell to another even during a voice call. There are mechanisms in the standard that allow for mobility, but their capabilities for QoS support are yet to be studied. This shows the large number of unresolved issues when it comes to Wireless LAN in the context of 4G networks. In this work we want to tackle some of the problems. KW - Drahtloses lokales Netz KW - Wireless LAN KW - Voice-over-IP (VoIP) KW - Quality-of-Service (QoS) KW - IEEE 802.11e KW - 4G Networks KW - Wireless LAN KW - Voice-over-IP (VoIP) KW - Quality-of-Service (QoS) KW - IEEE 802.11e KW - 4G Networks Y1 - 2005 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-14896 ER - TY - JOUR A1 - Hein, Rebecca M. A1 - Latoschik, Marc Erich A1 - Wienrich, Carolin T1 - Inter- and transcultural learning in cocial virtual reality: a proposal for an inter- and transcultural virtual object database to be used in the implementation, reflection, and evaluation of virtual encounters JF - Multimodal Technologies and Interaction N2 - Visual stimuli are frequently used to improve memory, language learning or perception, and understanding of metacognitive processes. However, in virtual reality (VR), there are few systematically and empirically derived databases. This paper proposes the first collection of virtual objects based on empirical evaluation for inter-and transcultural encounters between English- and German-speaking learners. We used explicit and implicit measurement methods to identify cultural associations and the degree of stereotypical perception for each virtual stimuli (n = 293) through two online studies, including native German and English-speaking participants. The analysis resulted in a final well-describable database of 128 objects (called InteractionSuitcase). In future applications, the objects can be used as a great interaction or conversation asset and behavioral measurement tool in social VR applications, especially in the field of foreign language education. For example, encounters can use the objects to describe their culture, or teachers can intuitively assess stereotyped attitudes of the encounters. KW - virtual stimuli KW - implicit association test KW - virtual reality KW - social VR KW - InteractionSuitcase Y1 - 2022 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-278974 SN - 2414-4088 VL - 6 IS - 7 ER - TY - JOUR A1 - Hein, Rebecca M. A1 - Wienrich, Carolin A1 - Latoschik, Marc E. T1 - A systematic review of foreign language learning with immersive technologies (2001-2020) JF - AIMS Electronics and Electrical Engineering N2 - This study provides a systematic literature review of research (2001–2020) in the field of teaching and learning a foreign language and intercultural learning using immersive technologies. Based on 2507 sources, 54 articles were selected according to a predefined selection criteria. The review is aimed at providing information about which immersive interventions are being used for foreign language learning and teaching and where potential research gaps exist. The papers were analyzed and coded according to the following categories: (1) investigation form and education level, (2) degree of immersion, and technology used, (3) predictors, and (4) criterions. The review identified key research findings relating the use of immersive technologies for learning and teaching a foreign language and intercultural learning at cognitive, affective, and conative levels. The findings revealed research gaps in the area of teachers as a target group, and virtual reality (VR) as a fully immersive intervention form. Furthermore, the studies reviewed rarely examined behavior, and implicit measurements related to inter- and trans-cultural learning and teaching. Inter- and transcultural learning and teaching especially is an underrepresented investigation subject. Finally, concrete suggestions for future research are given. The systematic review contributes to the challenge of interdisciplinary cooperation between pedagogy, foreign language didactics, and Human-Computer Interaction to achieve innovative teaching-learning formats and a successful digital transformation. KW - foreign language learning and teaching KW - intercultural learning and teaching KW - immersive technologies KW - education KW - human-computer interaction KW - systematic literature review Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-268811 VL - 5 IS - 2 ER - TY - THES A1 - Henjes, Robert T1 - Performance Evaluation of Publish/Subscribe Middleware Architectures T1 - Leistungsuntersuchung von Publish/Subscribe Middleware Architekturen N2 - While developing modern applications, it is necessary to ensure an efficient and performant communication between different applications. In current environments, a middleware software is used, which supports the publish/subscribe communication pattern. Using this communication pattern, a publisher sends information encapsulated in messages to the middleware. A subscriber registers its interests at the middleware. The monograph describes three different steps to determine the performance of such a system. In a first step, the message throughput performance of a publish/subscribe in different scenarios is measured using a Java Message Service (JMS) based implementation. In the second step the maximum achievable message throughput is described by adapted models depending on the filter complexity and the replication grade. Using the model, the performance characteristics of a specific system in a given scenario can be determined. These numbers are used for the queuing model described in the third part of the thesis, which supports the dimensioning of a system in realistic scenarios. Additionally, we introduce a method to approximate an M/G/1 system numerically in an efficient way, which can be used for real time analysis to predict the expected performance in a certain scenario. Finally, the analytical model is used to investigate different possibilities to ensure the scalability of the maximum achievable message throughput of the overall system. N2 - Bei der Entwicklung moderner Applikationen ist es notwendig eine effiziente und performante Kommunikation zwischen den einzelnen Anwendungen sicherzustellen. In der Praxis kommt dabei eine Middleware Software zum Einsatz, die das Publish/Subscribe Kommunikationsmuster unterstützt. Dabei senden Publisher Informationen in Form von Nachrichten an die Middleware. Die Subscriber hingegen zeigen durch die Nutzung von Filtern der Middleware an, welche Informationen zugestellt werden sollen. Die Arbeit beschreibt ein dreistufiges Verfahren zur Leistungsbestimmung eines solchen Systems. Zunächst wird durch Messung die Leistung von Publish/Subscribe Systemen in verschiedenen Szenarien untersucht am Beispiel von Java Message Service (JMS) basierten Implementierungen. Danach wird der maximale Nachrichtendurchsatz in Abhängigkeit der Filterkomplexität und des Nachrichtenreplikationsgrades durch einfache Modelle beschrieben. Damit können die Leistungskennwerte für ein System und vorgegebenen Randbedingungen beschrieben werden. Im dritten Teil wird mittels Leistungsbewertung und durch Anwendung eines Warteschlangenmodells die Leistung in praxisnahen Umfeld beschrieben, so dass eine Dimensionierung möglich wird. Zusätzlich wird ein mathematisch, approximatives Verfahren vorgestellt, um ein M/G/1 System numerisch effizient berechnen zu können, was bei der Echtzeitbewertung eines Systems zur Leistungsvorhersage benutzt werden kann. Des Weiteren werden mittels des Modells Möglichkeiten untersucht die Skalierbarkeit des Gesamtsystems in Bezug auf den Nachrichtendurchsatz sicherzustellen. T3 - Würzburger Beiträge zur Leistungsbewertung Verteilter Systeme - 04/10 KW - Middleware KW - Publish-Subscribe-System KW - Java Message Service KW - Leistungsbewertung KW - Middleware KW - Publish-Subscribe-System KW - Java Message Service KW - Performance Evaluation Y1 - 2010 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-53388 ER - TY - JOUR A1 - Hentschel, Simon A1 - Kobs, Konstantin A1 - Hotho, Andreas T1 - CLIP knows image aesthetics JF - Frontiers in Artificial Intelligence N2 - Most Image Aesthetic Assessment (IAA) methods use a pretrained ImageNet classification model as a base to fine-tune. We hypothesize that content classification is not an optimal pretraining task for IAA, since the task discourages the extraction of features that are useful for IAA, e.g., composition, lighting, or style. On the other hand, we argue that the Contrastive Language-Image Pretraining (CLIP) model is a better base for IAA models, since it has been trained using natural language supervision. Due to the rich nature of language, CLIP needs to learn a broad range of image features that correlate with sentences describing the image content, composition, environments, and even subjective feelings about the image. While it has been shown that CLIP extracts features useful for content classification tasks, its suitability for tasks that require the extraction of style-based features like IAA has not yet been shown. We test our hypothesis by conducting a three-step study, investigating the usefulness of features extracted by CLIP compared to features obtained from the last layer of a comparable ImageNet classification model. In each step, we get more computationally expensive. First, we engineer natural language prompts that let CLIP assess an image's aesthetic without adjusting any weights in the model. To overcome the challenge that CLIP's prompting only is applicable to classification tasks, we propose a simple but effective strategy to convert multiple prompts to a continuous scalar as required when predicting an image's mean aesthetic score. Second, we train a linear regression on the AVA dataset using image features obtained by CLIP's image encoder. The resulting model outperforms a linear regression trained on features from an ImageNet classification model. It also shows competitive performance with fully fine-tuned networks based on ImageNet, while only training a single layer. Finally, by fine-tuning CLIP's image encoder on the AVA dataset, we show that CLIP only needs a fraction of training epochs to converge, while also performing better than a fine-tuned ImageNet model. Overall, our experiments suggest that CLIP is better suited as a base model for IAA methods than ImageNet pretrained networks. KW - Image Aesthetic Assessment KW - CLIP KW - language-image pre-training KW - text supervision KW - prompt engineering KW - AVA Y1 - 2022 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-297150 SN - 2624-8212 VL - 5 ER - TY - THES A1 - Herrmann, Christian T1 - Robotic Motion Compensation for Applications in Radiation Oncology T1 - Robotergestützte Bewegungskompensation für Anwendungen in der Radioonkologie N2 - Aufgrund vieler Verbesserungen der Behandlungsmethoden im Laufe der letzten 60 Jahre, erlaubt die Strahlentherapie heutzutage präzise Behandlungen von statischen Tumoren. Jedoch birgt die Bestrahlung von sich bewegenden Tumoren noch große Herausforderungen in sich, da bewegliche Tumore oft den Behandlungsstrahl verlassen. Dabei reduziert sich die Strahlendosis im Tumor während sich diese im umliegenden gesunden Gewebe erhöht. Diese Forschungsarbeit zielt darauf ab, die Grenzen der Strahlentherapie zu erweitern, um präzise Behandlungen von beweglichen Tumoren zu ermöglichen. Der Fokus der Arbeit liegt auf der Erstellung eines Echtzeitsystems zur aktiven Kompensation von Tumorbewegungen durch robotergestützte Methoden. Während Behandlungen befinden sich Patienten auf einer Patientenliege, mit der statische Lagerungsfehler vor Beginn einer Behandlung korrigiert werden. Die in dieser Arbeit verwendete Patientenliege "HexaPOD" ist ein paralleler Manipulator mit sechs Freiheitsgraden, der große Lasten innerhalb eines eingeschränkten Arbeitsbereichs präzise positionieren kann. Obwohl der HexaPOD ursprünglich nicht für dynamische Anwendungen konzipiert wurde, wird dieser für eine dauerhafte Bewegungskompensation eingesetzt, in dem Patienten so bewegt werden, dass Tumore präzise im Zentralstrahl während der Dauer einer gesamten Behandlung verbleiben. Um ein echtzeitfähiges Kompensationssystem auf Basis des HexaPODs zu realisieren, muss eine Reihe an Herausforderungen bewältigt werden. Echtzeitaspekte werden einerseits durch die Verwendung eines harten Echtzeitbetriebssystems abgedeckt, andererseits durch die Messung und Schätzung von Latenzzeiten aller physikalischen Größen im System, z.B. Messungen der Tumor- und Atemposition. Neben der konsistenten und durchgängigen Berücksichtigung von akkuraten Zeitinformation, werden alle software-induzierten Latenzen adaptiv ausgeglichen. Dies erfordert Vorhersagen der Tumorposition in die nahe Zukunft. Zahlreiche Prädiktoren zur Atem- und Tumorpositionsvorhersage werden vorgeschlagen und anhand verschiedenster Metriken evaluiert. Erweiterungen der Prädiktionsalgorithmen werden eingeführt, die sowohl Atem- als auch Tumorpositionsinformationen fusionieren, um Vorhersagen ohne explizites Korrelationsmodell zu ermöglichen. Die Vorhersagen bestimmen den zukünftigen Bewegungspfad des HexaPODs, um Tumorbewegungen zu kompensieren. Dazu werden verschiedene Regler entwickelt, die eine Trajektorienverfolgung mit dem HexaPOD ermöglichen. Auf der Basis von linearer und nicht-linearer dynamischer Modellierung des HexaPODs mit Methoden der Systemidentifikation, wird zunächst ein modellprädiktiver Regler entwickelt. Ein zweiter Regler wird auf Basis einer Annahme über das Arbeitsprinzip des internen Reglers im HexaPOD entworfen. Schließlich wird ein dritter Regler vorgeschlagen, der beide vorhergehenden Regler miteinander kombiniert. Für jeden dieser Regler werden vergleichende Ergebnisse aus Experimenten mit realer Hardware und menschlichen Versuchspersonen präsentiert und diskutiert. Darüber hinaus wird die geeignete Wahl von freien Parametern in den Reglern vorgestellt. Neben einer präzisen Verfolgung der Referenztrajektorie spielt der Patientenkomfort eine entscheidende Rolle für die Akzeptanz des Systems. Es wird gezeigt, dass die Regler glatte Trajektorien realisieren können, um zu garantieren, dass sich Patienten wohl fühlen während ihre Tumorbewegung mit Genauigkeiten im Submillimeterbereich ausgeglichen wird. Gesamtfehler werden im Kompensationssystem analysiert, in dem diese zu Trajektorienverfolgungsfehlern und Prädiktionsfehlern in Beziehung gesetzt werden. Durch Ausnutzung von Eigenschaften verschiedener Prädiktoren wird gezeigt, dass die Startzeit des Systems bis die Verfolgung der Referenztrajektorie erreicht ist, wenige Sekunden beträgt. Dies gilt insbesondere für den Fall eines initial ruhenden HexaPODs und ohne Vorwissen über Tumorbewegungen. Dies zeigt die Eignung des Systems für die sehr kurz fraktionierten Behandlungen von Lungentumoren. Das Tumorkompensationssystem wurde ausschließlich auf Basis von klinischer Standard-Hardware entwickelt, die in vielen Behandlungsräumen zu finden ist. Durch ein einfaches und flexibles Design können Behandlungsräume in kosteneffizienter Weise um Möglichkeiten der Bewegungskompensation ergänzt werden. Darüber hinaus werden aktuelle Behandlungsmethoden wie intensitätsmodulierte Strahlentherapie oder Volumetric Modulated Arc Therapy in keiner Weise eingeschränkt. Aufgrund der Unterstützung verschiedener Kompensationsmodi kann das System auf alle beweglichen Tumore angewendet werden, unabhängig davon ob die Bewegungen vorhersagbar (Lungentumore) oder nicht vorhersagbar (Prostatatumore) sind. Durch Integration von geeigneten Methoden zur Tumorpositionsbestimmung kann das System auf einfache Weise zur Kompensation von anderen Tumoren erweitert werden. N2 - Radiation therapy today, on account of improvements in treatment procedures over the last 60 years, allows precise treatment of static tumors inside the human body. However, irradiation of moving tumors is still a challenging task as moving tumors often leave the treatment beam and the radiation dose delivered to the tumor reduces simultaneously increasing that on healthy tissue. This research work aims to push the frontiers of radiation therapy in order to enable precise treatment of moving tumors with focus on research and development of a unique real-time system enabling active motion compensation through robotic means to compensate tumor motion. During treatment, patients lie on a treatment couch which is normally used for static position corrections of patient set-up errors prior to radiation treatment. The treatment couch used, called HexaPOD, is a parallel manipulator with six degrees of freedom which can precisely position heavy loads inside a small region. Despite the HexaPOD not initially built with dynamics in mind, it is used in this work for sustained motion compensation by moving patients such that tumors stay precisely located at the center of the treatment beam during the complete course of treatment. In order to realize real-time tumor motion compensation by means of the HexaPOD, several challanges need to be addressed. Real-time aspects are covered by the adoption of a hard real-time operation system in combination with measurement and estimation of latencies of all physical quantities in the compensation system such as tumor or breathing position measurements. Accurate timing information is respected consistently in the whole system and all software-induced latencies are adaptively compensated for. This requires knowledge of future tumor positions from predictors. Several predictors for breathing and tumor motion predictions are proposed and evaluated in terms of a variety of different performance metrics. Extensions to prediction algorithms are introduced fusing both breathing and tumor position information to allow for predictions without the need of an explicit correlation model. Predictions determine the future motion path of the HexaPOD in order to compensate for tumor motion. Several control schemes are developed to enable reference tracking for the HexaPOD. Based on linear and non-linear dynamic modelling of the HexaPOD with system identification methods, a first controller is derived in the form of a model predictive controller. A second controller is proposed based on an assumption of the working principle of the HexaPOD's internal controller. Finally, a third controller is derived as combination of the first and second one. For each of these controllers, comparative results with real hardware experiments and humans in the loop as well as choices of free parameters are presented and discussed. Apart from precise tracking, emphasis is placed on patient comfort which is of crucial importance for acceptance of the system. It is demonstrated that smooth trajectories can be realized by the controllers to guarantee that patients feel comfortable while their tumor motion is compensated at sub-millimeter accuracies. Overall errors of the system are analyzed by relating them to tracking and prediction errors. By exploiting the properties of different predictors, it is shown that the startup time until tracking is reached can be reduced to only a few seconds, even in the case of an initially at-rest HexaPOD and with no initial knowledge of tumor motion. This makes the system especially suitable for the relatively short-fractionated treatment sessions for lung tumors. The tumor motion compensation system has been developed solely based on standard clinical hardware, found in most treatment rooms. With a simple and flexible design, existing treatment can be updated in a cost-efficient way to introduce motion compensation capabilities. Simultaneously, the system does not impose any constraints on state-of-the-art treatment types such as intensity modulated radiotherapy or volumetric modulated arc therapy. Supporting different compensation modes, the system can be applied to any moving tumor whether its motion is predictable (lung tumors) or unpredictable (prostate tumors). By integration of adequate tumor position determination methods, the system can be easily extended to other tumors as well. T3 - Forschungsberichte in der Robotik = Research Notes in Robotics - 7 KW - Robotik KW - Bewegungskompensation KW - Regelung KW - Strahlentherapie KW - Vorhersage KW - Tumorbewegung KW - Echzeit KW - Prediction KW - Tumor motion KW - Real-time Y1 - 2013 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-79045 SN - 978-3-923959-88-4 ER - TY - RPRT A1 - Herrmann, Martin A1 - Rizk, Amr T1 - On Data Plane Multipath Scheduling for Connected Mobility Applications T2 - KuVS Fachgespräch - Würzburg Workshop on Modeling, Analysis and Simulation of Next-Generation Communication Networks 2023 (WueWoWAS’23) N2 - Cooperative, connected and automated mobility (CCAM) systems depend on a reliable communication to provide their service and more crucially to ensure the safety of users. One way to ensure the reliability of a data transmission is to use multiple transmission technologies in combination with redundant flows. In this paper, we describe a system requiring multipath communication in the context of CCAM. To this end, we introduce a data plane-based scheduler that uses replication and integration modules to provide redundant and transparent multipath communication. We provide an analytical model for the full replication module of the system and give an overview of how and where the data-plane scheduler components can be realized. KW - multipath scheduling KW - connected mobility applications Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-322033 N1 - Aktualisierte Version unter https://doi.org/10.25972/OPUS-35344 ER - TY - RPRT A1 - Herrmann, Martin A1 - Rizk, Amr T1 - On Data Plane Multipath Scheduling for Connected Mobility Applications T2 - KuVS Fachgespräch - Würzburg Workshop on Modeling, Analysis and Simulation of Next-Generation Communication Networks 2023 (WueWoWAS’23) N2 - Cooperative, connected and automated mobility (CCAM) systems depend on a reliable communication to provide their service and more crucially to ensure the safety of users. One way to ensure the reliability of a data transmission is to use multiple transmission technologies in combination with redundant flows. In this paper, we describe a system requiring multipath communication in the context of CCAM. To this end, we introduce a data plane-based scheduler that uses replication and integration modules to provide redundant and transparent multipath communication. We provide an analytical model for the full replication module of the system and give an overview of how and where the data-plane scheduler components can be realized. KW - multipath scheduling KW - connected mobility applications Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-353444 N1 - Ursprüngliche Version unter https://doi.org/10.25972/OPUS-32203 ET - aktualisierte Version ER - TY - THES A1 - Hess, Martin T1 - Motion coordination and control in systems of nonholonomic autonomous vehicles T1 - Bewegungskoordination und Regelung in Gruppen nichtholonomer autonomer Fahrzeuge N2 - This work focuses on coordination methods and the control of motion in groups of nonholonomic wheeled mobile robots, in particular of the car-like type. These kind of vehicles are particularly restricted in their mobility. In the main part of this work the two problems of formation motion coordination and of rendezvous in distributed multi-vehicle systems are considered. We introduce several enhancements to an existing motion planning approach for formations of nonholonomic mobile robots. Compared to the original method, the extended approach is able to handle time-varying reference speeds as well as adjustments of the formation's shape during reference trajectory segments with continuously differentiable curvature. Additionally, undesired discontinuities in the speed and steering profiles of the vehicles are avoided. Further, the scenario of snow shoveling on an airfield by utilizing multiple formations of autonomous snowplows is discussed. We propose solutions to the subproblems of motion planning for the formations and tracking control for the individual vehicles. While all situations that might occur have been tested in a simulation environment, we also verified the developed tracking controller in real robot hardware experiments. The task of the rendezvous problem in groups of car-like robots is to drive all vehicles to a common position by means of decentralized control laws. Typically there exists no direct interaction link between all of the vehicles. In this work we present decentralized rendezvous control laws for vehicles with free and with bounded steering. The convergence properties of the approaches are analyzed by utilizing Lyapunov based techniques. Furthermore, they are evaluated within various simulation experiments, while the bounded steering case is also verified within laboratory hardware experiments. Finally we introduce a modification to the bounded steering system that increases the convergence speed at the expense of a higher traveled distance of the vehicles. N2 - Diese Arbeit befasst sich mit Methoden zur Bewegungskoordination und Regelung in Gruppen autonomer, nichtholomer Fahrzeuge, wobei vornehmlich autoähnliche mobile Roboter betrachtet werden. Diese Fahrzeuge sind besonders eingeschränkt in ihrer Bewegungsfreiheit. Im Hauptteil der Arbeit werden die Probleme der Formationsbewegung und des Rendezvous in Gruppen verteilter Fahrzeuge betrachtet. Für ein bestehendes Verfahren zur Bewegungsplanung für Formationen nichtholonomer, mobiler Fahrzeuge werden eine Reihe von Verbesserungen vorgestellt. Diese ermöglichen dem erweiterten Verfahren den Umgang mit Referenztrajektorien mit nicht-konstanter Geschwindigkeit und stetig differenzierbarer Krümmung. Außerdem werden im Gegensatz zum ursprünglichen Ansatz unerwünschte Sprungstellen in den Geschwindigkeits- und Krümmungsprofilen der Fahrzeuge vermieden. Desweiteren wird in dieser Arbeit das Schneeräumen auf Flughafenrollfeldern mittels Formationen autonomer Schneepflugfahrzeuge diskutiert. Dabei werden Lösungen für die Teilprobleme Bewegungsplanung der Formationen und Spurführungsregelung der einzelnen Fahrzeuge vorgestellt. Zusätzlich zu den durchgeführten Simulationen werden außerdem die Ergebnisse von Hardwareexperimenten mit der entwickelten Spurführungsregelung präsentiert. Das Rendezvous-Problem in Gruppen autoähnlicher Roboter besteht darin, die Fahrzeuge durch dezentrale Regelgesetze zu einer gemeinsamen Position in der Ebene zu bewegen. Dabei besteht typischerweise keine direkte Interaktionsverbindung zwischen allen Fahrzeugen der Gruppe. In dieser Arbeit werden verteilte Rendezvous-Regelgesetze für Fahrzeuge mit unbeschränktem und mit beschränktem Lenkwinkel eingeführt und deren Konvergenzeigenschaften mit Methoden zur Stabilitätsanalyse nicht-linearer Systeme untersucht. Die vorgestellten Regelsysteme werden weiterhin anhand von Simulationen und Hardwareexperimenten verifiziert. Schließlich wird noch eine Erweiterung des Systems für Fahrzeuge mit beschränktem Lenkwinkel vorgestellt, welches die Konvergenzgeschwindigkeit auf Kosten der zurückgelegten Distanz der Fahrzeuge erhöht. T3 - Forschungsberichte in der Robotik = Research Notes in Robotics - 2 KW - Robotik KW - Autonomer Roboter KW - Mobiler Roboter KW - Bewegungskoordination KW - Dezentrale Regelung KW - Nichtlineare Regelung KW - Rendezvous KW - Kooperierende mobile Roboter KW - Formationsbewegung KW - Nichtholonome Fahrzeuge KW - Mehrfahrzeugsysteme KW - Unstetige Regelung KW - Autonomous multi-vehicle systems KW - multi-vehicle formations KW - multi-vehicle rendezvous KW - car-like robots KW - nonholonomic vehicles Y1 - 2009 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-46442 SN - 978-3-923959-55-6 ER - TY - JOUR A1 - Hirth, Matthias A1 - Seufert, Michael A1 - Lange, Stanislav A1 - Meixner, Markus A1 - Tran-Gia, Phuoc T1 - Performance evaluation of hybrid crowdsensing and fixed sensor systems for event detection in urban environments JF - Sensors N2 - Crowdsensing offers a cost-effective way to collect large amounts of environmental sensor data; however, the spatial distribution of crowdsensing sensors can hardly be influenced, as the participants carry the sensors, and, additionally, the quality of the crowdsensed data can vary significantly. Hybrid systems that use mobile users in conjunction with fixed sensors might help to overcome these limitations, as such systems allow assessing the quality of the submitted crowdsensed data and provide sensor values where no crowdsensing data are typically available. In this work, we first used a simulation study to analyze a simple crowdsensing system concerning the detection performance of spatial events to highlight the potential and limitations of a pure crowdsourcing system. The results indicate that even if only a small share of inhabitants participate in crowdsensing, events that have locations correlated with the population density can be easily and quickly detected using such a system. On the contrary, events with uniformly randomly distributed locations are much harder to detect using a simple crowdsensing-based approach. A second evaluation shows that hybrid systems improve the detection probability and time. Finally, we illustrate how to compute the minimum number of fixed sensors for the given detection time thresholds in our exemplary scenario. KW - crowdsensing KW - event detection KW - detection time simulation KW - performance analysis Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-245245 SN - 1424-8220 VL - 21 IS - 17 ER - TY - THES A1 - Hock, David Rogér T1 - Analysis and Optimization of Resilient Routing in Core Communication Networks T1 - Analyse und Optimierung von ausfallsicherem Routing in Kernkommunikationsnetzen N2 - Routing is one of the most important issues in any communication network. It defines on which path packets are transmitted from the source of a connection to the destination. It allows to control the distribution of flows between different locations in the network and thereby is a means to influence the load distribution or to reach certain constraints imposed by particular applications. As failures in communication networks appear regularly and cannot be completely avoided, routing is required to be resilient against such outages, i.e., routing still has to be able to forward packets on backup paths even if primary paths are not working any more. Throughout the years, various routing technologies have been introduced that are very different in their control structure, in their way of working, and in their ability to handle certain failure cases. Each of the different routing approaches opens up their own specific questions regarding configuration, optimization, and inclusion of resilience issues. This monograph investigates, with the example of three particular routing technologies, some concrete issues regarding the analysis and optimization of resilience. It thereby contributes to a better general, technology-independent understanding of these approaches and of their diverse potential for the use in future network architectures. The first considered routing type, is decentralized intra-domain routing based on administrative IP link costs and the shortest path principle. Typical examples are common today's intra-domain routing protocols OSPF and IS-IS. This type of routing includes automatic restoration abilities in case of failures what makes it in general very robust even in the case of severe network outages including several failed components. Furthermore, special IP-Fast Reroute mechanisms allow for a faster reaction on outages. For routing based on link costs, traffic engineering, e.g. the optimization of the maximum relative link load in the network, can be done indirectly by changing the administrative link costs to adequate values. The second considered routing type, MPLS-based routing, is based on the a priori configuration of primary and backup paths, so-called Label Switched Paths. The routing layout of MPLS paths offers more freedom compared to IP-based routing as it is not restricted by any shortest path constraints but any paths can be setup. However, this in general involves a higher configuration effort. Finally, in the third considered routing type, typically centralized routing using a Software Defined Networking (SDN) architecture, simple switches only forward packets according to routing decisions made by centralized controller units. SDN-based routing layouts offer the same freedom as for explicit paths configured using MPLS. In case of a failure, new rules can be setup by the controllers to continue the routing in the reduced topology. However, new resilience issues arise caused by the centralized architecture. If controllers are not reachable anymore, the forwarding rules in the single nodes cannot be adapted anymore. This might render a rerouting in case of connection problems in severe failure scenarios infeasible. N2 - Routing stellt eine der zentralen Aufgaben in Kommunikationsnetzen dar. Es bestimmt darüber, auf welchem Weg Verkehr von der Quelle zum Ziel transportiert wird. Durch geschicktes Routing kann dadurch eine Verteilung der Verkehrsflüsse zum Beispiel zur Lastverteilung erreicht werden. Da Fehler in Kommunikationsnetzen nicht vollständig verhindert werden können, muss Routing insbesondere ausfallsicher sein, d.h., im Falle von Fehlern im Netz muss das Routing weiterhin in der Lage sein, Pakete auf alternativen Pfaden zum Ziel zu transportieren. Es existieren verschiedene gängige Routingverfahren und Technologien, die sich hinsichtlich Ihrer Arbeitsweise, Ihrer Kontrollstrukturen und Ihrer Funktionalität in bestimmten Fehlerszenarien unterscheiden. Für diese verschiedenen Ansätze ergeben sich jeweils eigene Fragestellungen hinsichtlich der Konfiguration, der Optimierung und der Berücksichtigung von Ausfallsicherheit. Diese Doktorarbeit behandelt am Beispiel bestimmter Technologien einige konkrete Fragestellungen zur Analyse und Optimierung der Ausfallsicherheit. Sie liefert damit einen Beitrag zum besseren generellen Verständnis verschiedenartiger Routingansätze und deren unterschiedlichen Potentials für den Einsatz in zukünftigen Netzarchitekturen. Zuerst wird dezentrales Routing behandelt, basierend auf administrativen Linkgewichten und dem Prinzip der kürzesten Pfade, wie es beispielsweise in den Protokollen IS-IS und OSPF genutzt wird. Diese Routingverfahren beinhalteten automatische Rekonvergenz-Mechanismen um im Falle von Fehlern auf der verbleibenden Netzstruktur weiterhin einen Transport von Verkehr zu ermöglichen. Spezielle IP-Fast Reroute Mechanismen ermöglichen zudem eine schnelle Reaktion im Falle von Fehlern. Routing basierend auf Linkgewichten lässt sich nur indirekt durch die Wahl geeigneter Gewichte beeinflussen und optimieren. Die zweite in der Doktorarbeit behandelte Routingart ist MPLS-basiertes Routing, bei dem Labels für Pakete verwendet werden und Pakete anhand sogenannter vorkonfigurierter Label Switched Paths weitergeleitet werden. Diese Technologie bietet mehr Freiheiten bei der Wahl des Pfadlayouts, was aber wiederum im Allgemeinen einen erhöhten Konfigurationsaufwand mit sich bringt. Schließlich greift die Doktorarbeit auch das Routing in SDN Netzen auf. Dort erfolgt eine Trennung von Control Plane und Data Plane, so dass einzelne dedizierte Controller die Routingentscheidungen festlegen und ansonsten einfache Switches mit reduzierter Komplexität den Verkehr lediglich entsprechend der festgelegten Regeln weiterleiten. Dies ermöglicht die größte Freiheit bei der Konfiguration des Routing bringt aber wiederum neue Fragestellungen bedingt durch die zentralen Kontrolleinheiten mit sich. T3 - Würzburger Beiträge zur Leistungsbewertung Verteilter Systeme - 02/14 KW - Leistungsbewertung KW - Verteiltes System KW - Routing KW - Netzwerk KW - Optimization KW - Routing KW - Software Defined Networking KW - Optimierung Y1 - 2014 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-101681 SN - 1432-8801 ER - TY - JOUR A1 - Holfelder, Marc A1 - Mulansky, Lena A1 - Schlee, Winfried A1 - Baumeister, Harald A1 - Schobel, Johannes A1 - Greger, Helmut A1 - Hoff, Andreas A1 - Pryss, Rüdiger T1 - Medical device regulation efforts for mHealth apps during the COVID-19 pandemic — an experience report of Corona Check and Corona Health JF - J — Multidisciplinary Scientific Journal N2 - Within the healthcare environment, mobile health (mHealth) applications (apps) are becoming more and more important. The number of new mHealth apps has risen steadily in the last years. Especially the COVID-19 pandemic has led to an enormous amount of app releases. In most countries, mHealth applications have to be compliant with several regulatory aspects to be declared a “medical app”. However, the latest applicable medical device regulation (MDR) does not provide more details on the requirements for mHealth applications. When developing a medical app, it is essential that all contributors in an interdisciplinary team — especially software engineers — are aware of the specific regulatory requirements beforehand. The development process, however, should not be stalled due to integration of the MDR. Therefore, a developing framework that includes these aspects is required to facilitate a reliable and quick development process. The paper at hand introduces the creation of such a framework on the basis of the Corona Health and Corona Check apps. The relevant regulatory guidelines are listed and summarized as a guidance for medical app developments during the pandemic and beyond. In particular, the important stages and challenges faced that emerged during the entire development process are highlighted. KW - mHealth KW - mobile application KW - MDR KW - medical device regulation KW - medical device software Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-285434 SN - 2571-8800 VL - 4 IS - 2 SP - 206 EP - 222 ER - TY - THES A1 - Hopfner, Marbod T1 - Source Code Analysis, Management, and Visualization for PROLOG T1 - Quelltextanalyse, Verwaltung und Visualisierung für Prolog N2 - This thesis deals with the management and analysis of source code, which is represented in XML. Using the elementary methods of the XML repository, the XML source code representation is accessed, changed, updated, and saved. We reason about the source code, refactor source code and we visualize dependency graphs for call analysis. The visualized dependencies between files, modules, or packages are used to structure the source code in order to get a system, which is easily to comprehend, to modify and to complete. Sophisticated methods have been developed to slice the source code in order to obtain a working package of a large system, containing only a specific functionality. The basic methods, on which the visualizations and analyses are built on can be changed like changing a plug-in. The visualization methods can be reused in order to handle arbitrary source code representations, e.g., JAML, PHPML, PROLOGML. Dependencies of other context can be visualized, too, e.g., ER diagrams, or website references. The tool SCAV supports source code visualization and analyzing methods. N2 - Diese Dissertation beschäftigt sich mit der Verwaltung und Analyse von Quellcode, der in XML repräsentiert ist. Es werden Abhängigkeitsgraphen visualisiert um ein Projekt leichter verstehen zu können. Es kann auch ein Slice einer bestimmten Methode aus dem Projekt erstellt werden. Die Programmierung ist in Modulen gemacht, so dass die Funktionalität leicht erweitert werden kann. KW - Refactoring KW - Software Engineering KW - Refactoring KW - Call Graph KW - Dependency Graph KW - Abhängigskeitsgraph KW - Software Engineering KW - Source Code Visualization KW - Refactoring KW - Call Graph KW - Dependency Graph KW - Abhängigskeitsgraph KW - Software Engineering KW - Source Code Visualization Y1 - 2008 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-36300 ER - TY - JOUR A1 - Hossfeld, Tobias A1 - Heegaard, Poul E. A1 - Kellerer, Wolfgang T1 - Comparing the scalability of communication networks and systems JF - IEEE Access N2 - Scalability is often mentioned in literature, but a stringent definition is missing. In particular, there is no general scalability assessment which clearly indicates whether a system scales or not or whether a system scales better than another. The key contribution of this article is the definition of a scalability index (SI) which quantifies if a system scales in comparison to another system, a hypothetical system, e.g., linear system, or the theoretically optimal system. The suggested SI generalizes different metrics from literature, which are specialized cases of our SI. The primary target of our scalability framework is, however, benchmarking of two systems, which does not require any reference system. The SI is demonstrated and evaluated for different use cases, that are (1) the performance of an IoT load balancer depending on the system load, (2) the availability of a communication system depending on the size and structure of the network, (3) scalability comparison of different location selection mechanisms in fog computing with respect to delays and energy consumption; (4) comparison of time-sensitive networking (TSN) mechanisms in terms of efficiency and utilization. Finally, we discuss how to use and how not to use the SI and give recommendations and guidelines in practice. To the best of our knowledge, this is the first work which provides a general SI for the comparison and benchmarking of systems, which is the primary target of our scalability analysis. KW - communication networks KW - performance KW - availability KW - scalability Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-349403 VL - 11 ER - TY - THES A1 - Houshiar, Hamidreza T1 - Documentation and mapping with 3D point cloud processing T1 - Dokumentation und Kartierung mittels 3D-Punktwolkenverarbeitung N2 - 3D point clouds are a de facto standard for 3D documentation and modelling. The advances in laser scanning technology broadens the usability and access to 3D measurement systems. 3D point clouds are used in many disciplines such as robotics, 3D modelling, archeology and surveying. Scanners are able to acquire up to a million of points per second to represent the environment with a dense point cloud. This represents the captured environment with a very high degree of detail. The combination of laser scanning technology with photography adds color information to the point clouds. Thus the environment is represented more realistically. Full 3D models of environments, without any occlusion, require multiple scans. Merging point clouds is a challenging process. This thesis presents methods for point cloud registration based on the panorama images generated from the scans. Image representation of point clouds introduces 2D image processing methods to 3D point clouds. Several projection methods for the generation of panorama maps of point clouds are presented in this thesis. Additionally, methods for point cloud reduction and compression based on the panorama maps are proposed. Due to the large amounts of data generated from the 3D measurement systems these methods are necessary to improve the point cloud processing, transmission and archiving. This thesis introduces point cloud processing methods as a novel framework for the digitisation of archeological excavations. The framework replaces the conventional documentation methods for excavation sites. It employs point clouds for the generation of the digital documentation of an excavation with the help of an archeologist on-site. The 3D point cloud is used not only for data representation but also for analysis and knowledge generation. Finally, this thesis presents an autonomous indoor mobile mapping system. The mapping system focuses on the sensor placement planning method. Capturing a complete environment requires several scans. The sensor placement planning method solves for the minimum required scans to digitise large environments. Combining this method with a navigation system on a mobile robot platform enables it to acquire data fully autonomously. This thesis introduces a novel hole detection method for point clouds to detect obscured parts of a captured environment. The sensor placement planning method selects the next scan position with the most coverage of the obscured environment. This reduces the required number of scans. The navigation system on the robot platform consist of path planning, path following and obstacle avoidance. This guarantees the safe navigation of the mobile robot platform between the scan positions. The sensor placement planning method is designed as a stand alone process that could be used with a mobile robot platform for autonomous mapping of an environment or as an assistant tool for the surveyor on scanning projects. N2 - 3D-Punktwolken sind der de facto Standard bei der Dokumentation und Modellierung in 3D. Die Fortschritte in der Laserscanningtechnologie erweitern die Verwendbarkeit und die Verfügbarkeit von 3D-Messsystemen. 3D-Punktwolken werden in vielen Disziplinen verwendet, wie z.B. in der Robotik, 3D-Modellierung, Archäologie und Vermessung. Scanner sind in der Lage bis zu einer Million Punkte pro Sekunde zu erfassen, um die Umgebung mit einer dichten Punktwolke abzubilden und mit einem hohen Detaillierungsgrad darzustellen. Die Kombination der Laserscanningtechnologie mit Methoden der Photogrammetrie fügt den Punktwolken Farbinformationen hinzu. Somit wird die Umgebung realistischer dargestellt. Vollständige 3D-Modelle der Umgebung ohne Verschattungen benötigen mehrere Scans. Punktwolken zusammenzufügen ist eine anspruchsvolle Aufgabe. Diese Arbeit stellt Methoden zur Punktwolkenregistrierung basierend auf aus den Scans erzeugten Panoramabildern vor. Die Darstellung einer Punktwolke als Bild bringt Methoden der 2D-Bildverarbeitung an 3D-Punktwolken heran. Der Autor stellt mehrere Projektionsmethoden zur Erstellung von Panoramabildern aus 3D-Punktwolken vor. Außerdem werden Methoden zur Punktwolkenreduzierung und -kompression basierend auf diesen Panoramabildern vorgeschlagen. Aufgrund der großen Datenmenge, die von 3D-Messsystemen erzeugt wird, sind diese Methoden notwendig, um die Punktwolkenverarbeitung, -übertragung und -archivierung zu verbessern. Diese Arbeit präsentiert Methoden der Punktwolkenverarbeitung als neuartige Ablaufstruktur für die Digitalisierung von archäologischen Ausgrabungen. Durch diesen Ablauf werden konventionellen Methoden auf Ausgrabungsstätten ersetzt. Er verwendet Punktwolken für die Erzeugung der digitalen Dokumentation einer Ausgrabung mithilfe eines Archäologen vor Ort. Die 3D-Punktwolke kommt nicht nur für die Anzeige der Daten, sondern auch für die Analyse und Wissensgenerierung zum Einsatz. Schließlich stellt diese Arbeit ein autonomes Indoor-Mobile-Mapping-System mit Fokus auf der Positionsplanung des Messgeräts vor. Die Positionsplanung bestimmt die minimal benötigte Anzahl an Scans, um großflächige Umgebungen zu digitalisieren. Kombiniert mit einem Navigationssystem auf einer mobilen Roboterplattform ermöglicht diese Methode die vollautonome Datenerfassung. Diese Arbeit stellt eine neuartige Erkennungsmethode für Lücken in Punktwolken vor, um verdeckte Bereiche der erfassten Umgebung zu bestimmen. Die Positionsplanung bestimmt als nächste Scanposition diejenige mit der größten Abdeckung der verdeckten Umgebung. Das Navigationssystem des Roboters besteht aus der Pfadplanung, der Pfadverfolgung und einer Hindernisvermeidung um eine sichere Fortbewegung der mobilen Roboterplattform zwischen den Scanpositionen zu garantieren. Die Positionsplanungsmethode wurde als eigenständiges Verfahren entworfen, das auf einer mobilen Roboterplattform zur autonomen Kartierung einer Umgebung zum Einsatz kommen oder einem Vermesser bei einem Scanprojekt als Unterstützung dienen kann. T3 - Forschungsberichte in der Robotik = Research Notes in Robotics - 12 KW - 3D Punktwolke KW - Robotik KW - Registrierung KW - 3D Pointcloud KW - Feature Based Registration KW - Compression KW - Computer Vision KW - Robotics KW - Panorama Images Y1 - 2017 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-144493 SN - 978-3-945459-14-0 ER - TY - THES A1 - Hoßfeld, Tobias T1 - Performance Evaluation of Future Internet Applications and Emerging User Behavior T1 - Leistungsbewertung von zukünftigen Internet-Applikationen und auftretenden Nutzerverhaltens N2 - In future telecommunication systems, we observe an increasing diversity of access networks. The separation of transport services and applications or services leads to multi-network services, i.e., a future service has to work transparently to the underlying network infrastructure. Multi-network services with edge-based intelligence, like P2P file sharing or the Skype VoIP service, impose new traffic control paradigms on the future Internet. Such services adapt the amount of consumed bandwidth to reach different goals. A selfish behavior tries to keep the QoE of a single user above a certain level. Skype, for instance, repeats voice samples depending on the perceived end-to-end loss. From the viewpoint of a single user, the replication of voice data overcomes the degradation caused by packet loss and enables to maintain a certain QoE. The cost for this achievement is a higher amount of consumed bandwidth. However, if the packet loss is caused by congestion in the network, this additionally required bandwidth even worsens the network situation. Altruistic behavior, on the other side, would reduce the bandwidth consumption in such a way that the pressure on the network is released and thus the overall network performance is improved. In this monograph, we analyzed the impact of the overlay, P2P, and QoE paradigms in future Internet applications and the interactions from the observing user behavior. The shift of intelligence toward the edge is accompanied by a change in the emerging user behavior and traffic profile, as well as a change from multi-service networks to multi-networks services. In addition, edge-based intelligence may lead to a higher dynamics in the network topology, since the applications are often controlled by an overlay network, which can rapidly change in size and structure as new nodes can leave or join the overlay network in an entirely distributed manner. As a result, we found that the performance evaluation of such services provides new challenges, since novel key performance factors have to be first identified, like pollution of P2P systems, and appropriate models of the emerging user behavior are required, e.g. taking into account user impatience. As common denominator of the presented studies in this work, we focus on a user-centric view when evaluating the performance of future Internet applications. For a subscriber of a certain application or service, the perceived quality expressed as QoE will be the major criterion of the user's satisfaction with the network and service providers. We selected three different case studies and characterized the application's performance from the end user's point of view. Those are (1) cooperation in mobile P2P file sharing networks, (2) modeling of online TV recording services, and (3) QoE of edge-based VoIP applications. The user-centric approach facilitates the development of new mechanisms to overcome problems arising from the changing user behavior. An example is the proposed CycPriM cooperation strategy, which copes with selfish user behavior in mobile P2P file sharing system. An adequate mechanism has also been shown to be efficient in a heterogeneous B3G network with mobile users conducting vertical handovers between different wireless access technologies. The consideration of the user behavior and the user perceived quality guides to an appropriate modeling of future Internet applications. In the case of the online TV recording service, this enables the comparison between different technical realizations of the system, e.g. using server clusters or P2P technology, to properly dimension the installed network elements and to assess the costs for service providers. Technologies like P2P help to overcome phenomena like flash crowds and improve scalability compared to server clusters, which may get overloaded in such situations. Nevertheless, P2P technology invokes additional challenges and different user behavior to that seen in traditional client/server systems. Beside the willingness to share files and the churn of users, peers may be malicious and offer fake contents to disturb the data dissemination. Finally, the understanding and the quantification of QoE with respect to QoS degradations permits designing sophisticated edge-based applications. To this end, we identified and formulated the IQX hypothesis as an exponential interdependency between QoE and QoS parameters, which we validated for different examples. The appropriate modeling of the emerging user behavior taking into account the user's perceived quality and its interactions with the overlay and P2P paradigm will finally help to design future Internet applications. N2 - Applikationen im heutigen Internet werden immer mehr durch intelligente Endknoten bereitgestellt, deren Kommunikation in logischen, virtuellen Netzwerken, (Overlays) realisiert wird. Die verstärkte Diensterbringung durch solche Overlays, wie zum Beispiel bei Peer-to-Peer Dateitauschbörsen oder Telefonie über das Internet, wird durch einen Paradigmenwechsel von Multi-Service Networks zu Multi-Network Services beschrieben. Während in einem Multi-Service Network verschiedene Dienste innerhalb eines Netzes angeboten werden, beschreibt ein Multi-Network Service die Diensterbringung über verschiedene Netze und Netzzugangstechnologien, wie es im Internet der Fall ist. Dadurch kann die technische Güte des Telekommunikationsdienstes (Quality of Service, QoS) nicht mehr die alleinige Metrik für die Qualität eines Dienstes sein. Stattdessen ist die vom Nutzer erfahrene Dienstgüte (User Perceived Quality of Experience, QoE) zu betrachten. Diese QoE muss entsprechend modelliert werden, um die Performanz von heutigen oder auch zukünftigen Internetapplikationen zu beurteilen. Die Berücksichtigung der QoE beinhaltet unter anderem auch neuartige Verhaltensweisen der Teilnehmer, die ebenfalls modelliert werden müssen. Ein Beispiel ist der Dienstabbruch durch ungeduldige Nutzer beim Herunterladen von Filmen oder bei nicht ausreichender Qualität bei Internet-Telefonie. Durch die Verschiebung der Intelligenz von Applikationen in Richtung Endknoten entstehen neu aufkommende Verhaltensweisen der Teilnehmer und sich ändernde Charakteristika des Netzwerkverkehrs, die sie von klassischen Client-Server-Anwendungen unterscheiden. Beispiele hierfür sind egoistisches oder altruistisches Nutzerverhalten bei der Einbringung von Endnutzer-Ressourcen zur Diensterbringung oder auch bösartiges Nutzerverhalten bei der gezielten Störung eines Dienstes (Pollution). In beiden Fällen sind die zeitdynamischen Verhaltensmuster (Churn, Flash Crowds) zu berücksichtigen. Um die ausgedehnten Overlay. Netze zu planen und zu evaluieren, sind überdies auch neue Leistungsbewertungsmodelle notwendig, damit zum Beispiel die Simulation skaliert oder aber auch zeitdynamische Nutzerverhalten in analytischen Modellen abgebildet wird. Diese Doktorarbeit arbeitet diese Aspekte an drei Anwendungsbeispielen auf: Verteilernetz für Dateiinhalte (Content Distribution Network), Netzwerk-basierte Videorekorder (Online TV Recorder) und Sprachtelefonie über P2P (VoP2P). Die Ergebnisse und Untersuchungen dieser Arbeit gliedern sich entsprechend dieser Anwendungsbeispiele. T3 - Würzburger Beiträge zur Leistungsbewertung Verteilter Systeme - 01/09 KW - Leistungsbewertung KW - Peer-to-Peer-Netz KW - Dienstgüte KW - Overlay-Netz KW - Mathematische Modellierung KW - BitTorrent KW - Skype KW - Warteschlangentheorie KW - zukünftiges Internet KW - vom Nutzer erfahrene Dienstgüte QoE KW - Multi-Netzwerk Dienste KW - intelligente Applikationen KW - Verteilung von Inhalten KW - Future Internet KW - Quality of Experience QoE KW - Multi-Network Service KW - Edge-based Intelligence KW - Content Distribution Y1 - 2009 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-37570 ER - TY - THES A1 - Huber, Stephan T1 - Proxemo: Documenting Observed Emotions in HCI T1 - Proxemo: Die Dokumentation Beobachteter Emotionen in der Mensch-Computer-Interaktion N2 - For formative evaluations of user experience (UX) a variety of methods have been developed over the years. However, most techniques require the users to interact with the study as a secondary task. This active involvement in the evaluation is not inclusive of all users and potentially biases the experience currently being studied. Yet there is a lack of methods for situations in which the user has no spare cognitive resources. This condition occurs when 1) users' cognitive abilities are impaired (e.g., people with dementia) or 2) users are confronted with very demanding tasks (e.g., air traffic controllers). In this work we focus on emotions as a key component of UX and propose the new structured observation method Proxemo for formative UX evaluations. Proxemo allows qualified observers to document users' emotions by proxy in real time and then directly link them to triggers. Technically this is achieved by synchronising the timestamps of emotions documented by observers with a video recording of the interaction. In order to facilitate the documentation of observed emotions in highly diverse contexts we conceptualise and implement two separate versions of a documentation aid named Proxemo App. For formative UX evaluations of technology-supported reminiscence sessions with people with dementia, we create a smartwatch app to discreetly document emotions from the categories anger, general alertness, pleasure, wistfulness and pride. For formative UX evaluations of prototypical user interfaces with air traffic controllers we create a smartphone app to efficiently document emotions from the categories anger, boredom, surprise, stress and pride. Descriptive case studies in both application domains indicate the feasibility and utility of the method Proxemo and the appropriateness of the respectively adapted design of the Proxemo App. The third part of this work is a series of meta-evaluation studies to determine quality criteria of Proxemo. We evaluate Proxemo regarding its reliability, validity, thoroughness and effectiveness, and compare Proxemo's efficiency and the observers' experience to documentation with pen and paper. Proxemo is reliable, as well as more efficient, thorough and effective than handwritten notes and provides a better UX to observers. Proxemo compares well with existing methods where benchmarks are available. With Proxemo we contribute a validated structured observation method that has shown to meet requirements formative UX evaluations in the extreme contexts of users with cognitive impairments or high task demands. Proxemo is agnostic regarding researchers' theoretical approaches and unites reductionist and holistic perspectives within one method. Future work should explore the applicability of Proxemo for further domains and extend the list of audited quality criteria to include, for instance, downstream utility. With respect to basic research we strive to better understand the sources leading observers to empathic judgments and propose reminisce and older adults as model environment for investigating mixed emotions. N2 - Für formative Evaluationen der User Experience (UX) wurden im Laufe der Jahre zahlreiche Methoden entwickelt. Die meisten Methoden erfordern jedoch, dass die Benutzer als Nebenaufgabe mit der Studie interagieren. Diese aktive Beteiligung an der Evaluation kann das untersuchte Erlebnis verfälschen und schließt Benutzer komplett aus, die keine kognitiven Ressourcen zur Verfügung haben. Dies ist der Fall, wenn 1) die kognitiven Fähigkeiten der Benutzer beeinträchtigt sind (z. B. Menschen mit Demenz) oder 2) Benutzer mit sehr anspruchsvollen Aufgaben konfrontiert sind (z. B. Fluglotsen). In dieser Arbeit konzentrieren wir uns auf Emotionen als eine Schlüsselkomponente von UX und schlagen die neue strukturierte Beobachtungsmethode Proxemo für formative UX-Evaluationen vor. Proxemo ermöglicht es qualifizierten Beobachtern, die Emotionen der Nutzer in Echtzeit zu dokumentieren und sie direkt mit Auslösern zu verknüpfen. Technisch wird dies erreicht, indem die Zeitstempel der von den Beobachtern dokumentierten Emotionen mit einer Videoaufzeichnung der Interaktion synchronisiert werden. Um die Dokumentation von beobachteten Emotionen in sehr unterschiedlichen Kontexten zu erleichtern, konzipieren und implementieren wir zwei verschiedene Versionen einer Dokumentationshilfe namens Proxemo App. Für formative UX-Evaluationen von technologiegestützten Erinnerungssitzungen mit Menschen mit Demenz erstellen wir eine Smartwatch-App zur unauffälligen Dokumentation von Emotionen aus den Kategorien Ärger, allgemeine Wachsamkeit, Freude, Wehmut und Stolz. Für formative UX-Evaluationen prototypischer Nutzerschnittstellen mit Fluglotsen erstellen wir eine Smartphone-App zur effizienten Dokumentation von Emotionen aus den Kategorien Ärger, Langeweile, Überraschung, Stress und Stolz. Deskriptive Fallstudien in beiden Anwendungsfeldern zeigen die Machbarkeit und den Nutzen der Methode Proxemo und die Angemessenheit des jeweiligen Designs der Proxemo App. Der dritte Teil dieser Arbeit besteht aus einer Reihe von Meta-Evaluationsstudien zu den Gütekriterien von Proxemo. Wir evaluieren Proxemo hinsichtlich der Reliabilität, Validität, Gründlichkeit und Effektivität, und vergleichen die Effizienz von Proxemo und die UX der Beobachter mit der Dokumentation mit Stift und Papier. Proxemo ist reliabel, sowie effizienter, gründlicher und effektiver als handschriftliche Notizen und bietet den Beobachtern eine bessere UX. Proxemo schneidet gut ab im Vergleich zu bestehenden Methoden, für die Benchmarks verfügbar sind. Mit Proxemo stellen wir eine validierte, strukturierte Beobachtungsmethode vor, die nachweislich den Anforderungen formativer UX Evaluationen in den extremen Kontexten von Benutzern mit kognitiven Beeinträchtigungen oder hohen Aufgabenanforderungen gerecht wird. Proxemo ist agnostisch bezüglich der theoretischen Ansätze von Forschenden und vereint reduktionistische und ganzheitliche Perspektiven in einer Methode. Zukünftige Arbeiten sollten die Anwendbarkeit von Proxemo für weitere Domänen erkunden und die Liste der geprüften Gütekriterien erweitern, zum Beispiel um das Kriterium Downstream Utility. In Bezug auf die Grundlagenforschung werden wir versuchen, die Quellen besser zu verstehen, auf denen die empathischen Urteile der Beobachter fußen und schlagen Erinnerungen und ältere Erwachsene als Modellumgebung für die künftige Erforschung gemischter Emotionen vor. KW - Gefühl KW - Wissenschaftliche Beobachtung KW - Methode KW - Benutzererlebnis KW - Benutzerforschung KW - Emotionserkennung KW - Emotion inference KW - Emotionsinterpretation Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-305730 ER - TY - JOUR A1 - Hurtienne, Jörn T1 - Inter-coder reliability of categorising force-dynamic events in human-technology interaction N2 - Two studies are reported that investigate how readily accessible and applicable ten force-dynamic categories are to novices in describing short episodes of human-technology interaction (Study 1) and that establish a measure of inter-coder reliability when re-classifying these episodes into force-dynamic categories (Study 2). The results of the first study show that people can easily and confidently relate their experiences with technology to the definitions of force-dynamic events (e.g. “The driver released the handbrake” as an example of restraint removal). The results of the second study show moderate agreement between four expert coders across all ten force-dynamic categories (Cohen’s kappa = .59) when re-classifying these episodes. Agreement values for single force-dynamic categories ranged between ‘fair’ and ‘almost perfect’, i.e. between kappa = .30 and .95. Agreement with the originally intended classifications of study 1 was higher than the pure inter-coder reliabilities. Single coders achieved an average kappa of .71, indicating substantial agreement. Using more than one coder increased kappas to almost perfect: up to .87 for four coders. A qualitative analysis of the predicted versus the observed number of category confusions revealed that about half of the category disagreement could be predicted from strong overlaps in the definitions of force-dynamic categories. From the quantitative and qualitative results, guidelines are derived to aid the better training of coders in order to increase inter-coder reliability. KW - inter-coder reliability KW - force dynamics KW - image schemas KW - humantechnology interaction Y1 - 2013 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-194127 SN - 2197-2796 SN - 2197-2788 N1 - This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively. VL - 1 IS - 1 ER - TY - RPRT A1 - Höweler, Malte A1 - Xiang, Zuo A1 - Höpfner, Franz A1 - Nguyen, Giang T. A1 - Fitzek, Frank H. P. T1 - Towards Stateless Core Networks: Measuring State Access Patterns T2 - Würzburg Workshop on Next-Generation Communication Networks (WueWoWas'22) N2 - Future mobile communication networks, such as 5G and beyond, can benefit from Virtualized Network Functions (VNFs) when deployed on cloud infrastructures to achieve elasticity and scalability. However, new challenges arise as to managing states of Network Functions (NFs). Especially control plane VNFs, which are mainly found in cellular core networks like the 5G Core (5GC), received little attention since the shift towards virtualizing NFs. Most existing solutions for these core networks are often complex, intrusive, and are seldom compliant with the standard. With the emergence of 5G campus networks, UEs will be mainly machine-type devices. These devices communicate more deterministically, bringing new opportunities for elaborated state management. This work presents an emulation environment to perform rigorous measurements on state access patterns. The emulation comes with a fully parameterized Markov model for the UE to examine a wide variety of different devices. These measurements can then be used as a solid base for designing an efficient, simple, and standard conform state management solution that brings us further towards stateless core networks. KW - Datennetz KW - 5GC KW - VNF KW - SBA KW - measurements KW - MTC Y1 - 2022 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-280770 ER - TY - THES A1 - Jarschel, Michael T1 - An Assessment of Applications and Performance Analysis of Software Defined Networking T1 - Eine Untersuchung von Anwendungen und Leistungsbewertung von Software Defined Networking N2 - With the introduction of OpenFlow by the Stanford University in 2008, a process began in the area of network research, which questions the predominant approach of fully distributed network control. OpenFlow is a communication protocol that allows the externalization of the network control plane from the network devices, such as a router, and to realize it as a logically-centralized entity in software. For this concept, the term "Software Defined Networking" (SDN) was coined during scientific discourse. For the network operators, this concept has several advantages. The two most important can be summarized under the points cost savings and flexibility. Firstly, it is possible through the uniform interface for network hardware ("Southbound API"), as implemented by OpenFlow, to combine devices and software from different manufacturers, which increases the innovation and price pressure on them. Secondly, the realization of the network control plane as a freely programmable software with open interfaces ("Northbound API") provides the opportunity to adapt it to the individual circumstances of the operator's network and to exchange information with the applications it serves. This allows the network to be more flexible and to react more quickly to changing circumstances as well as transport the traffic more effectively and tailored to the user’s "Quality of Experience" (QoE). The approach of a separate network control layer for packet-based networks is not new and has already been proposed several times in the past. Therefore, the SDN approach has raised many questions about its feasibility in terms of efficiency and applicability. These questions are caused to some extent by the fact that there is no generally accepted definition of the SDN concept to date. It is therefore a part of this thesis to derive such a definition. In addition, several of the open issues are investigated. This Investigations follow the three aspects: Performance Evaluation of Software Defined Networking, applications on the SDN control layer, and the usability of SDN Northbound-API for creation application-awareness in network operation. Performance Evaluation of Software Defined Networking: The question of the efficiency of an SDN-based system was from the beginning one of the most important. In this thesis, experimental measurements of the performance of OpenFlow-enabled switch hardware and control software were conducted for the purpose of answering this question. The results of these measurements were used as input parameters for establishing an analytical model of the reactive SDN approach. Through the model it could be determined that the performance of the software control layer, often called "Controller", is crucial for the overall performance of the system, but that the approach is generally viable. Based on this finding a software for analyzing the performance of SDN controllers was developed. This software allows the emulation of the forwarding layer of an SDN network towards the control software and can thus determine its performance in different situations and configurations. The measurements with this software showed that there are quite significant differences in the behavior of different control software implementations. Among other things it has been shown that some show different characteristics for various switches, in particular in terms of message processing speed. Under certain circumstances this can lead to network failures. Applications on the SDN control layer: The core piece of software defined networking are the intelligent network applications that operate on the control layer. However, their development is still in its infancy and little is known about the technical possibilities and their limitations. Therefore, the relationship between an SDN-based and classical implementation of a network function is investigated in this thesis. This function is the monitoring of network links and the traffic they carry. A typical approach for this task has been built based on Wiretapping and specialized measurement hardware and compared with an implementation based on OpenFlow switches and a special SDN control application. The results of the comparison show that the SDN version can compete in terms of measurement accuracy for bandwidth and delay estimation with the traditional measurement set-up. However, a compromise has to be found for measurements below the millisecond range. Another question regarding the SDN control applications is whether and how well they can solve existing problems in networks. Two programs have been developed based on SDN in this thesis to solve two typical network issues. Firstly, the tool "IPOM", which enables considerably more flexibility in the study of effects of network structures for a researcher, who is confined to a fixed physical test network topology. The second software provides an interface between the Cloud Orchestration Software "OpenNebula" and an OpenFlow controller. The purpose of this software was to investigate experimentally whether a pre-notification of the network of an impending relocation of a virtual service in a data center is sufficient to ensure the continuous operation of that service. This was demonstrated on the example of a video service. Usability of the SDN Northbound API for creating application-awareness in network operation: Currently, the fact that the network and the applications that run on it are developed and operated separately leads to problems in network operation. SDN offers with the Northbound-API an open interface that enables the exchange between information of both worlds during operation. One aim of this thesis was to investigate whether this interface can be exploited so that the QoE experienced by the user can be maintained on high level. For this purpose, the QoE influence factors were determined on a challenging application by means of a subjective survey study. The application is cloud gaming, in which the calculation of video game environments takes place in the cloud and is transported via video over the network to the user. It was shown that apart from the most important factor influencing QoS, i.e., packet loss on the downlink, also the type of game type and its speed play a role. This demonstrates that in addition to QoS the application state is important and should be communicated to the network. Since an implementation of such a state conscious SDN for the example of Cloud Gaming was not possible due to its proprietary implementation, in this thesis the application “YouTube video streaming” was chosen as an alternative. For this application, status information is retrievable via the "Yomo" tool and can be used for network control. It was shown that an SDN-based implementation of an application-aware network has distinct advantages over traditional network management methods and the user quality can be obtained in spite of disturbances. N2 - Mit der Vorstellung von OpenFlow durch die Stanford Universität im Jahre 2008 begann ein Prozess im Bereich der Netzwerkforschung, der den vorherrschenden Ansatz der völlig verteilten Netzsteuerung in Frage stellt. Bei OpenFlow handelt es sich um ein Kommunikationsprotokoll, das es ermöglicht die Netzsteuerung aus den Netzwerkgeräten, z. B. einem Router, herauszulösen und als logisch-zentralisierte Einheit als reine Software zu realisieren. Ein Konzept für das im Verlauf des wissenschaftlichen Diskurses der Begriff „Software Defined Networking“ (SDN) geprägt wurde. Für die Betreiber von Netzwerken hat dieses Konzept verschiedene Vorteile. Die beiden wichtigsten lassen sich unter den Punkten Kostenersparnis und Flexibilität zusammenfassen. Zum einen ist es durch die einheitliche Schnittstelle zur Netzwerkhardware („Southbound-API“), wie sie von OpenFlow realisiert wird, möglich Geräte und Software verschiedener Hersteller miteinander zu kombinieren, was den Innovations- und Preisdruck auf diese erhöht. Zum anderen besteht durch die Realisierung der Netzwerksteuerung als frei programmierbare Software mit offenen Schnittstellen („Northbound-API“) die Möglichkeit diese an die individuellen Gegebenheiten des Betreibernetzes anzupassen als auch Informationen mit den Applikationen auszutauschen, die es bedient. Dadurch kann das Netz viel flexibler und schneller auf sich ändernde Gegebenheiten reagieren und den Verkehr effektiver und auf die vom Nutzer erfahrene „Quality of Experience“ (QoE) abgestimmt transportieren. Der Ansatz einer von der Hardware getrennten Netzwerkkontrollschicht für paket-basierte Netze ist nicht neu und wurde in der Vergangenheit bereits mehrfach vorgeschlagen. Daher sah und sieht sich der Ansatz von SDN vielen Fragen nach seiner Realisierbarkeit im Bezug auf Leistungsfähigkeit und Anwendbarkeit gegenüber. Diese Fragen rühren zum Teil auch daher, dass es bis dato keine allgemein anerkannte Definition des SDN Begriffes gibt. Daher ist es ein Teil dieser Doktorarbeit eine solche Definition herzuleiten. Darüber hinaus werden verschiedene der offenen Fragen auf ihre Lösung hin untersucht. Diese Untersuchungen folgen drei Teilaspekten: Leistungsbewertung von Software Defined Networking, Anwendungen auf der SDN Kontrollschicht und die Nutzbarkeit der SDN Northbound-API zum Herstellen eines Applikationsbewusstseins im Netzbetrieb. Leistungsbewertung von Software Defined Networking: Die Frage nach der Leistungsfähigkeit eines SDN-basierten Systems war von Beginn an eine der wichtigsten. In dieser Doktorarbeit wurden zu diesem Zweck experimentelle Messungen zur Leistung OpenFlow-fähiger Switch Hardware und Kontrollsoftware durchgeführt. Die Ergebnisse dieser Messungen dienten als Eingabeparameter zur Aufstellung eines analytischen Modells des reaktiven SDN Ansatzes. Durch das Modell ließ sich bestimmen, dass die Leistungsfähigkeit der Software Kontrollschicht, oft „Controller“ genannt, von entscheidender Bedeutung für die Gesamtleistung des Systems ist, aber der Ansatz insgesamt tragfähig ist. Basierend auf dieser Erkenntnis wurde eine Software zur Analyse der Leistungsfähigkeit von SDN Controllern entwickelt. Diese Software ermöglicht die Emulation der Weiterleitungsschicht eines SDN Netzes gegenüber der Kontrollsoftware und kann so deren Leistungsdaten in verschiedenen Situationen und Konfigurationen bestimmen. Die Messungen mit dieser Software zeigten, dass es durchaus gravierende Unterschiede im Verhalten verschiedener Kontrollsoftware Implementierungen gibt. Unter anderem konnte gezeigt werden, dass einige gegenüber verschiedenen Switches ein unterschiedliches Verhalten aufweisen, insbesondere in der Abarbeitungsgeschwindigkeit von Nachrichten. Ein Umstand der in bestimmten Fällen zu Netzausfällen führen kann. Anwendungen auf der SDN Kontrollschicht: Das Kernstück von Software Defined Networking sind die intelligenten Netzwerkapplikationen, die auf der Kontrollschicht betrieben werden. Allerdings steht deren Entwicklung noch am Anfang und es ist wenig über die technischen Möglichkeiten und deren Grenzen bekannt. Daher wurde in dieser Doktorarbeit der Frage nachgegangen, in welchem Verhältnis sich die Realisierung einer Netzwerkaufgabe mit SDN zur klassischen Umsetzung dieser bewegt. Bei dieser Aufgabe handelt es sich im speziellen um das Monitoring von Links und dem darauf befindlichen Netzwerkverkehr. Hier wurde ein typischer Ansatz für diese Aufgabe basierend auf Wiretapping und spezieller Messhardware aufgebaut und mit einer Implementierung durch OpenFlow Switches und einer speziellen SDN Kontrollapplikation verglichen. Die Ergebnisse des Vergleiches zeigen, dass die SDN Variante im Bezug auf Bandbreiten und Verzögerungsabschätzung durchaus mit dem traditionellen Messaufbau im Bezug auf Messgenauigkeit mithalten kann. Jedoch müssen Abstriche bezüglich der Verzögerungsmessung unterhalb des Millisekundenbereiches gemacht werden. Eine weitere Frage bezüglich der SDN Kontrollapplikationen besteht darin, ob und wie gut sich bestehende Probleme in Netzwerken jetzt mit SDN lösen lassen. Diesbezüglich wurden in dieser Doktorarbeit zwei Programme auf SDN Basis entwickelt, die zwei typische Netzwerkprobleme lösen. Zum einen das Tool „IPOM“, dass es ermöglicht via SDN auf Basis einer festen physikalischen Testnetz-Topologie eine andere zu emulieren und so einem Forscher auf dem Testnetz deutlich mehr Flexibilität bei der Untersuchung von Auswirkungen anderer Netzstrukturen zu ermöglichen. Die zweite Software stellt eine Schnittstelle zwischen der Cloud Orchestration Software „OpenNebula“ und einem OpenFlow Controller dar. Der Zweck dieser Software war es experimentell zu untersuchen, ob eine Vorwarnung des Netzes vor einem bevorstehenden Umzug eines virtuellen Dienstes in einem Datenzentrum hinreichend ist, um den kontinuierlichen Betrieb dieses Dienstes zu gewährleisten. Dieses konnte am Beispiel eines Videodienstes demonstriert werden. Nutzbarkeit der SDN Northbound-API zum Herstellen eines Applikationsbewusstseins im Netzbetrieb: Aktuell führt die Tatsache, dass Netz und Applikationen, die darauf laufen, separat entwickelt und betrieben werden zu Problemen im Netzbetrieb. SDN bietet mit der Northbound-API eine Schnittstelle an, die den Austausch zwischen Informationen beider Welten im Betrieb ermöglicht. Ein Ziel dieser Doktorarbeit war es zu untersuchen, ob sich diese Schnittstelle ausnutzen lässt, so dass die vom Nutzer erfahrene QoE hoch gehalten werden kann. Zu diesem Zwecke wurden zunächst mittels einer subjektiven Umfragestudie die Einflussfaktoren auf eine anspruchsvolle Applikation bestimmt. Bei der Applikation handelt es sich um Cloud Gaming, bei dem die Berechnung der Videospiele Umgebung in der Cloud stattfindet und per Video über das Netz transportiert wird. Hier konnte gezeigt werden, dass neben dem wichtigsten QoS Einflussfaktor Paketverlust auf dem Downlink auch die Art des Spieltyps und dessen Geschwindigkeit eine Rolle spielen. Dies belegt, dass neben QoS auch der Applikationszustand wichtig ist und dem Netz mitgeteilt werden sollte. Da eine Umsetzung eines solchen zustandsbewussten SDNs für das Beispiel Cloud Gaming auf Grund dessen proprietärer Implementierung nicht möglich war, wurde in dieser Doktorarbeit auf die Applikation YouTube Video Streaming ausgewichen. Für diese sind mit Hilfe des Tools „YoMo“ Statusinformationen abfragbar und können zur Netzsteuerung genutzt werden. Es konnte gezeigt werden, dass eine SDN-basierte Realisierung eines applikationsbewussten Netzes deutliche Vorteile gegenüber klassischen Netzwerk Management Methoden aufweist und die Nutzerqualität trotz Störfaktoren erhalten werden kann. T3 - Würzburger Beiträge zur Leistungsbewertung Verteilter Systeme - 03/14 KW - Leistungsbewertung KW - Netzwerk KW - Software Defined Networking KW - Quality of Experience KW - Cloud Gaming KW - Performance Evaluation Y1 - 2014 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-100795 SN - 1432-8801 ER - TY - JOUR A1 - Kaiser, Dennis A1 - Lesch, Veronika A1 - Rothe, Julian A1 - Strohmeier, Michael A1 - Spieß, Florian A1 - Krupitzer, Christian A1 - Montenegro, Sergio A1 - Kounev, Samuel T1 - Towards Self-Aware Multirotor Formations JF - Computers N2 - In the present day, unmanned aerial vehicles become seemingly more popular every year, but, without regulation of the increasing number of these vehicles, the air space could become chaotic and uncontrollable. In this work, a framework is proposed to combine self-aware computing with multirotor formations to address this problem. The self-awareness is envisioned to improve the dynamic behavior of multirotors. The formation scheme that is implemented is called platooning, which arranges vehicles in a string behind the lead vehicle and is proposed to bring order into chaotic air space. Since multirotors define a general category of unmanned aerial vehicles, the focus of this thesis are quadcopters, platforms with four rotors. A modification for the LRA-M self-awareness loop is proposed and named Platooning Awareness. The implemented framework is able to offer two flight modes that enable waypoint following and the self-awareness module to find a path through scenarios, where obstacles are present on the way, onto a goal position. The evaluation of this work shows that the proposed framework is able to use self-awareness to learn about its environment, avoid obstacles, and can successfully move a platoon of drones through multiple scenarios. KW - self-aware computing KW - unmanned aerial vehicles KW - multirotors KW - quadcopters KW - intelligent transportation systems Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-200572 SN - 2073-431X VL - 9 IS - 1 ER - TY - JOUR A1 - Kaltdorf, Kristin Verena A1 - Schulze, Katja A1 - Helmprobst, Frederik A1 - Kollmannsberger, Philip A1 - Dandekar, Thomas A1 - Stigloher, Christian T1 - Fiji macro 3D ART VeSElecT: 3D automated reconstruction tool for vesicle structures of electron tomograms JF - PLoS Computational Biology N2 - Automatic image reconstruction is critical to cope with steadily increasing data from advanced microscopy. We describe here the Fiji macro 3D ART VeSElecT which we developed to study synaptic vesicles in electron tomograms. We apply this tool to quantify vesicle properties (i) in embryonic Danio rerio 4 and 8 days past fertilization (dpf) and (ii) to compare Caenorhabditis elegans N2 neuromuscular junctions (NMJ) wild-type and its septin mutant (unc-59(e261)). We demonstrate development-specific and mutant-specific changes in synaptic vesicle pools in both models. We confirm the functionality of our macro by applying our 3D ART VeSElecT on zebrafish NMJ showing smaller vesicles in 8 dpf embryos then 4 dpf, which was validated by manual reconstruction of the vesicle pool. Furthermore, we analyze the impact of C. elegans septin mutant unc-59(e261) on vesicle pool formation and vesicle size. Automated vesicle registration and characterization was implemented in Fiji as two macros (registration and measurement). This flexible arrangement allows in particular reducing false positives by an optional manual revision step. Preprocessing and contrast enhancement work on image-stacks of 1nm/pixel in x and y direction. Semi-automated cell selection was integrated. 3D ART VeSElecT removes interfering components, detects vesicles by 3D segmentation and calculates vesicle volume and diameter (spherical approximation, inner/outer diameter). Results are collected in color using the RoiManager plugin including the possibility of manual removal of non-matching confounder vesicles. Detailed evaluation considered performance (detected vesicles) and specificity (true vesicles) as well as precision and recall. We furthermore show gain in segmentation and morphological filtering compared to learning based methods and a large time gain compared to manual segmentation. 3D ART VeSElecT shows small error rates and its speed gain can be up to 68 times faster in comparison to manual annotation. Both automatic and semi-automatic modes are explained including a tutorial. KW - Biology KW - Vesicles KW - Caenorhabditis elegans KW - Zebrafish KW - Septins KW - Synaptic vesicles KW - Neuromuscular junctions KW - Computer software KW - Synapses Y1 - 2017 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-172112 VL - 13 IS - 1 ER - TY - JOUR A1 - Kammerer, Klaus A1 - Göster, Manuel A1 - Reichert, Manfred A1 - Pryss, Rüdiger T1 - Ambalytics: a scalable and distributed system architecture concept for bibliometric network analyses JF - Future Internet N2 - A deep understanding about a field of research is valuable for academic researchers. In addition to technical knowledge, this includes knowledge about subareas, open research questions, and social communities (networks) of individuals and organizations within a given field. With bibliometric analyses, researchers can acquire quantitatively valuable knowledge about a research area by using bibliographic information on academic publications provided by bibliographic data providers. Bibliometric analyses include the calculation of bibliometric networks to describe affiliations or similarities of bibliometric entities (e.g., authors) and group them into clusters representing subareas or communities. Calculating and visualizing bibliometric networks is a nontrivial and time-consuming data science task that requires highly skilled individuals. In addition to domain knowledge, researchers must often provide statistical knowledge and programming skills or use software tools having limited functionality and usability. In this paper, we present the ambalytics bibliometric platform, which reduces the complexity of bibliometric network analysis and the visualization of results. It accompanies users through the process of bibliometric analysis and eliminates the need for individuals to have programming skills and statistical knowledge, while preserving advanced functionality, such as algorithm parameterization, for experts. As a proof-of-concept, and as an example of bibliometric analyses outcomes, the calculation of research fronts networks based on a hybrid similarity approach is shown. Being designed to scale, ambalytics makes use of distributed systems concepts and technologies. It is based on the microservice architecture concept and uses the Kubernetes framework for orchestration. This paper presents the initial building block of a comprehensive bibliometric analysis platform called ambalytics, which aims at a high usability for users as well as scalability. KW - system architecture design KW - bibliometric analysis KW - community detection Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-244916 SN - 1999-5903 VL - 13 IS - 8 ER - TY - JOUR A1 - Kammerer, Klaus A1 - Pryss, Rüdiger A1 - Hoppenstedt, Burkhard A1 - Sommer, Kevin A1 - Reichert, Manfred T1 - Process-driven and flow-based processing of industrial sensor data JF - Sensors N2 - For machine manufacturing companies, besides the production of high quality and reliable machines, requirements have emerged to maintain machine-related aspects through digital services. The development of such services in the field of the Industrial Internet of Things (IIoT) is dealing with solutions such as effective condition monitoring and predictive maintenance. However, appropriate data sources are needed on which digital services can be technically based. As many powerful and cheap sensors have been introduced over the last years, their integration into complex machines is promising for developing digital services for various scenarios. It is apparent that for components handling recorded data of these sensors they must usually deal with large amounts of data. In particular, the labeling of raw sensor data must be furthered by a technical solution. To deal with these data handling challenges in a generic way, a sensor processing pipeline (SPP) was developed, which provides effective methods to capture, process, store, and visualize raw sensor data based on a processing chain. Based on the example of a machine manufacturing company, the SPP approach is presented in this work. For the company involved, the approach has revealed promising results. KW - data stream processing KW - cyber-physical systems KW - processing pipeline KW - sensor networks Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-213089 SN - 1424-8220 VL - 20 IS - 18 ER - TY - THES A1 - Karch, Oliver T1 - Where am I? - Indoor localization based on range measurements T1 - Wo bin ich? - Lokalisation mit Hilfe von Entfernungsmesswerten N2 - Nowadays, robotics plays an important role in increasing fields of application. There exist many environments or situations where mobile robots instead of human beings are used, since the tasks are too hazardous, uncomfortable, repetitive, or costly for humans to perform. The autonomy and the mobility of the robot are often essential for a good solution of these problems. Thus, such a robot should at least be able to answer the question "Where am I?". This thesis investigates the problem of self-localizing a robot in an indoor environment using range measurements. That is, a robot equipped with a range sensor wakes up inside a building and has to determine its position using only its sensor data and a map of its environment. We examine this problem from an idealizing point of view (reducing it into a pure geometric one) and further investigate a method of Guibas, Motwani, and Raghavan from the field of computational geometry to solving it. Here, so-called visibility skeletons, which can be seen as coarsened representations of visibility polygons, play a decisive role. In the major part of this thesis we analyze the structures and the occurring complexities in the framework of this scheme. It turns out that the main source of complication are so-called overlapping embeddings of skeletons into the map polygon, for which we derive some restrictive visibility constraints. Based on these results we are able to improve one of the occurring complexity bounds in the sense that we can formulate it with respect to the number of reflex vertices instead of the total number of map vertices. This also affects the worst-case bound on the preprocessing complexity of the method. The second part of this thesis compares the previous idealizing assumptions with the properties of real-world environments and discusses the occurring problems. In order to circumvent these problems, we use the concept of distance functions, which model the resemblance between the sensor data and the map, and appropriately adapt the above method to the needs of realistic scenarios. In particular, we introduce a distance function, namely the polar coordinate metric, which seems to be well suited to the localization problem. Finally, we present the RoLoPro software where most of the discussed algorithms are implemented (including the polar coordinate metric). N2 - Heutzutage spielen autonome Roboter bei einer wachsenden Zahl von Anwendungsgebieten eine entscheidende Rolle. Sie werden überall dort anstelle von menschlichen Arbeitskräften eingesetzt, wo die jeweiligen Aufgaben für Menschen zu gefährlich, unangenehm, monoton oder schlicht zu teuer sind. Dabei sind die Autonomie und Mobilität des Roboters sehr oft grundlegend für eine gute Problemlösung. Ein solcher Roboter sollte also zumindest die Frage "Wo bin ich?" zufriedenstellend beantworten können. Diese Arbeit behandelt das Problem der Selbstlokalisation in einer Gebäudeumgebung mit Hilfe von Entfernungsmesswerten. Das heißt, ein Roboter - ausgestattet mit einem Entfernungssensor - wacht innerhalb eines Gebäudes auf und muss mit Hilfe seiner Sensordaten und einer Karte seiner Einsatzumgebung seine Position bestimmen. Wir betrachten eine idealisierte Variante dieser Aufgabe, die ein rein geometrisches Problem zum Inhalt hat, und untersuchen ein Verfahren von Guibas, Motwani und Raghavan aus dem Gebiet der Algorithmischen Geometrie, welches dieses löst. Hierbei spielen sogenannte Sichtbarkeitsskelette (vergröberte Darstellungen von Sichtbarkeitspolygonen) eine entscheidende Rolle. Im Hauptteil der Arbeit analysieren wir die Strukturen und die auftretenden Komplexitäten im Rahmen dieses Verfahrens. Es stellt sich heraus, dass die Hauptschwierigkeiten sogenannte überlappende Einbettungen von Skeletten in das Kartenpolygon zur Ursache haben, für die wir einige einschränkende Sichtbarkeitsbedingungen zeigen. Gestützt auf diese Resultate können wir die auftretenden Komplexitätsschranken dahingehend verbessern, dass wir diese nicht nur in Abhängigkeit der Gesamtzahl aller Kartenecken angeben, sondern in Abhängigkeit der Zahl der konkaven Ecken. Dies hat ebenfalls Auswirkungen auf die Worst-Case-Schranken für die Preprocessing-Komplexität des Verfahrens. Der zweite Teil der Arbeit vergleicht die anfangs gemachten idealisierenden Annahmen mit den Gegebenheiten realer Umgebungen und adressiert die auftretenden Probleme. Um diese zu umgehen verwenden wir das Konzept sogenannter Distanzfunktionen, welche die Ähnlichkeit zwischen den Sensordaten und der Karte modellieren, und passen das Verfahren auf geeignete Weise an die Bedürfnisse realistischer Szenarien an. Insbesondere führen wir eine Distanzfunktion ein - die Polarkoordinatenmetrik - welche sich für das Lokalisationsproblem besonders gut zu eignen scheint. Schlussendlich stellen wir die Software RoLoPro vor, in der die meisten der diskutierten Algorithmen (einschließlich der Polarkoordinatenmetrik) implementiert sind. KW - Autonomer Roboter KW - Mobiler Roboter KW - Lokalisation KW - Lokalisation KW - Autonomer Roboter KW - Sichtbarkeit KW - Ähnlichkeitsmaß KW - Algorithmische Geometrie KW - Localization KW - Autonomous Robot KW - Visibility KW - Similarity Measure KW - Computational Geometry Y1 - 2002 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-8442 ER - TY - JOUR A1 - Karl, Stefan A1 - Dandekar, Thomas T1 - Jimena: Efficient computing and system state identification for genetic regulatory networks JF - BMC Bioinformatics N2 - Background: Boolean networks capture switching behavior of many naturally occurring regulatory networks. For semi-quantitative modeling, interpolation between ON and OFF states is necessary. The high degree polynomial interpolation of Boolean genetic regulatory networks (GRNs) in cellular processes such as apoptosis or proliferation allows for the modeling of a wider range of node interactions than continuous activator-inhibitor models, but suffers from scaling problems for networks which contain nodes with more than ~10 inputs. Many GRNs from literature or new gene expression experiments exceed those limitations and a new approach was developed. Results: (i) As a part of our new GRN simulation framework Jimena we introduce and setup Boolean-tree-based data structures; (ii) corresponding algorithms greatly expedite the calculation of the polynomial interpolation in almost all cases, thereby expanding the range of networks which can be simulated by this model in reasonable time. (iii) Stable states for discrete models are efficiently counted and identified using binary decision diagrams. As application example, we show how system states can now be sampled efficiently in small up to large scale hormone disease networks (Arabidopsis thaliana development and immunity, pathogen Pseudomonas syringae and modulation by cytokinins and plant hormones). Conclusions: Jimena simulates currently available GRNs about 10-100 times faster than the previous implementation of the polynomial interpolation model and even greater gains are achieved for large scale-free networks. This speed-up also facilitates a much more thorough sampling of continuous state spaces which may lead to the identification of new stable states. Mutants of large networks can be constructed and analyzed very quickly enabling new insights into network robustness and behavior. KW - Boolean function KW - genetic regulatory network KW - interpolation KW - stable state KW - binary decision diagram KW - Boolean tree Y1 - 2013 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-128671 VL - 14 ER - TY - JOUR A1 - Kempf, Sebastian A1 - Krug, Markus A1 - Puppe, Frank T1 - KIETA: Key-insight extraction from scientific tables JF - Applied Intelligence N2 - An important but very time consuming part of the research process is literature review. An already large and nevertheless growing ground set of publications as well as a steadily increasing publication rate continue to worsen the situation. Consequently, automating this task as far as possible is desirable. Experimental results of systems are key-insights of high importance during literature review and usually represented in form of tables. Our pipeline KIETA exploits these tables to contribute to the endeavor of automation by extracting them and their contained knowledge from scientific publications. The pipeline is split into multiple steps to guarantee modularity as well as analyzability, and agnosticim regarding the specific scientific domain up until the knowledge extraction step, which is based upon an ontology. Additionally, a dataset of corresponding articles has been manually annotated with information regarding table and knowledge extraction. Experiments show promising results that signal the possibility of an automated system, while also indicating limits of extracting knowledge from tables without any context. KW - table extraction KW - table understanding KW - ontology KW - key-insight extraction KW - information extraction Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-324180 SN - 0924-669X VL - 53 IS - 8 ER - TY - JOUR A1 - Kern, Florian A1 - Kullmann, Peter A1 - Ganal, Elisabeth A1 - Korwisi, Kristof A1 - Stingl, René A1 - Niebling, Florian A1 - Latoschik, Marc Erich T1 - Off-The-Shelf Stylus: Using XR Devices for Handwriting and Sketching on Physically Aligned Virtual Surfaces JF - Frontiers in Virtual Reality N2 - This article introduces the Off-The-Shelf Stylus (OTSS), a framework for 2D interaction (in 3D) as well as for handwriting and sketching with digital pen, ink, and paper on physically aligned virtual surfaces in Virtual, Augmented, and Mixed Reality (VR, AR, MR: XR for short). OTSS supports self-made XR styluses based on consumer-grade six-degrees-of-freedom XR controllers and commercially available styluses. The framework provides separate modules for three basic but vital features: 1) The stylus module provides stylus construction and calibration features. 2) The surface module provides surface calibration and visual feedback features for virtual-physical 2D surface alignment using our so-called 3ViSuAl procedure, and surface interaction features. 3) The evaluation suite provides a comprehensive test bed combining technical measurements for precision, accuracy, and latency with extensive usability evaluations including handwriting and sketching tasks based on established visuomotor, graphomotor, and handwriting research. The framework’s development is accompanied by an extensive open source reference implementation targeting the Unity game engine using an Oculus Rift S headset and Oculus Touch controllers. The development compares three low-cost and low-tech options to equip controllers with a tip and includes a web browser-based surface providing support for interacting, handwriting, and sketching. The evaluation of the reference implementation based on the OTSS framework identified an average stylus precision of 0.98 mm (SD = 0.54 mm) and an average surface accuracy of 0.60 mm (SD = 0.32 mm) in a seated VR environment. The time for displaying the stylus movement as digital ink on the web browser surface in VR was 79.40 ms on average (SD = 23.26 ms), including the physical controller’s motion-to-photon latency visualized by its virtual representation (M = 42.57 ms, SD = 15.70 ms). The usability evaluation (N = 10) revealed a low task load, high usability, and high user experience. Participants successfully reproduced given shapes and created legible handwriting, indicating that the OTSS and it’s reference implementation is ready for everyday use. We provide source code access to our implementation, including stylus and surface calibration and surface interaction features, making it easy to reuse, extend, adapt and/or replicate previous results (https://go.uniwue.de/hci-otss). KW - virtual reality KW - augmented reality KW - handwriting KW - sketching KW - stylus KW - user interaction KW - usability evaluation KW - passive haptic feedback Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-260219 VL - 2 ER - TY - THES A1 - Kindermann, Philipp T1 - Angular Schematization in Graph Drawing N2 - Graphs are a frequently used tool to model relationships among entities. A graph is a binary relation between objects, that is, it consists of a set of objects (vertices) and a set of pairs of objects (edges). Networks are common examples of modeling data as a graph. For example, relationships between persons in a social network, or network links between computers in a telecommunication network can be represented by a graph. The clearest way to illustrate the modeled data is to visualize the graphs. The field of Graph Drawing deals with the problem of finding algorithms to automatically generate graph visualizations. The task is to find a "good" drawing, which can be measured by different criteria such as number of crossings between edges or the used area. In this thesis, we study Angular Schematization in Graph Drawing. By this, we mean drawings with large angles (for example, between the edges at common vertices or at crossing points). The thesis consists of three parts. First, we deal with the placement of boxes. Boxes are axis-parallel rectangles that can, for example, contain text. They can be placed on a map to label important sites, or can be used to describe semantic relationships between words in a word network. In the second part of the thesis, we consider graph drawings visually guide the viewer. These drawings generally induce large angles between edges that meet at a vertex. Furthermore, the edges are drawn crossing-free and in a way that makes them easy to follow for the human eye. The third and final part is devoted to crossings with large angles. In drawings with crossings, it is important to have large angles between edges at their crossing point, preferably right angles. N2 - Graphen sind häufig verwendete Werkzeuge zur Modellierung von Zusammenhängen zwischen Daten. Ein Graph ist eine binäre Relation zwischen Objekten, das heißt er besteht aus einer Menge von Objekten (Knoten) und einer Menge von Paaren von Objekten (Kanten). Netzwerke sind übliche Beispiele für das Modellieren von Daten als ein Graph. Beispielsweise lassen sich Beziehungen zwischen Personen in einem sozialen Netzwerk oder Netzanbindungen zwischen Computern in einem Telekommunikationsnetz als Graph darstellen. Die modellierten Daten können am anschaulichsten dargestellt werden, indem man die Graphen visualisiert. Der Bereich des Graphenzeichnens behandelt das Problem, Algorithmen zum automatischen Erzeugen von Graphenvisualisierungen zu finden. Das Ziel ist es, eine "gute" Zeichnung zu finden, was durch unterschiedliche Kriterien gemessen werden kann; zum Beispiel durch die Anzahl der Kreuzungen zwischen Kanten oder durch den Platzverbrauch. In dieser Arbeit beschäftigen wir uns mit Winkelschematisierung im Graphenzeichnen. Darunter verstehen wir Zeichnungen, in denen die Winkel (zum Beispiel zwischen Kanten an einem gemeinsamen Knoten oder einem Kreuzungspunkt) möglichst groß gestaltet sind. Die Arbeit besteht aus drei Teilen. Im ersten Teil betrachten wir die Platzierung von Boxen. Boxen sind achsenparallele Rechtecke, die zum Beispiel Text enthalten. Sie können beispielsweise auf einer Karte platziert werden, um wichtige Standorte zu beschriften, oder benutzt werden, um semantische Beziehungen zwischen Wörtern in einem Wortnetzwerk darzustellen. Im zweiten Teil der Arbeit untersuchen wir Graphenzeichnungen, die den Betrachter visuell führen. Im Allgemeinen haben diese Zeichnungen große Winkel zwischen Kanten, die sich in einem Knoten treffen. Außerdem werden die Verbindungen kreuzungsfrei und so gezeichnet, dass es dem menschlichen Auge leicht fällt, ihnen zu folgen. Im dritten und letzten Teil geht es um Kreuzungen mit großen Winkeln. In Zeichnungen mit Kreuzungen ist es wichtig, dass die Winkel zwischen Kanten an Kreuzungspunkten groß sind, vorzugsweise rechtwinklig. KW - graph drawing KW - angular schematization KW - boundary labeling KW - contact representation KW - word clouds KW - monotone drawing KW - smooth orthogonal drawing KW - simultaneous embedding KW - right angle crossing KW - independent crossing KW - Graphenzeichnen KW - Winkel KW - Kreuzung KW - v Y1 - 2016 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-112549 SN - 978-3-95826-020-7 (print) SN - 978-3-95826-021-4 (online) PB - Würzburg University Press CY - Würzburg ER - TY - JOUR A1 - Kirikkayis, Yusuf A1 - Gallik, Florian A1 - Winter, Michael A1 - Reichert, Manfred T1 - BPMNE4IoT: a framework for modeling, executing and monitoring IoT-driven processes JF - Future Internet N2 - The Internet of Things (IoT) enables a variety of smart applications, including smart home, smart manufacturing, and smart city. By enhancing Business Process Management Systems with IoT capabilities, the execution and monitoring of business processes can be significantly improved. Providing a holistic support for modeling, executing and monitoring IoT-driven processes, however, constitutes a challenge. Existing process modeling and process execution languages, such as BPMN 2.0, are unable to fully meet the IoT characteristics (e.g., asynchronicity and parallelism) of IoT-driven processes. In this article, we present BPMNE4IoT—A holistic framework for modeling, executing and monitoring IoT-driven processes. We introduce various artifacts and events based on the BPMN 2.0 metamodel that allow realizing the desired IoT awareness of business processes. The framework is evaluated along two real-world scenarios from two different domains. Moreover, we present a user study for comparing BPMNE4IoT and BPMN 2.0. In particular, this study has confirmed that the BPMNE4IoT framework facilitates the support of IoT-driven processes. KW - IoT KW - BPM KW - BPMN KW - IoT-driven processes Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-304097 SN - 1999-5903 VL - 15 IS - 3 ER - TY - THES A1 - Klein, Alexander T1 - Performance Issues of MAC and Routing Protocols in Wireless Sensor Networks T1 - Leistungsbeschränkende Faktoren von MAC und Routingprotokollen in drahtlosen Sensornetzen N2 - The focus of this work lies on the communication issues of Medium Access Control (MAC) and routing protocols in the context of WSNs. The communication challenges in these networks mainly result from high node density, low bandwidth, low energy constraints and the hardware limitations in terms of memory, computational power and sensing capabilities of low-power transceivers. For this reason, the structure of WSNs is always kept as simple as possible to minimize the impact of communication issues. Thus, the majority of WSNs apply a simple one hop star topology since multi-hop communication has high demands on the routing protocol since it increases the bandwidth requirements of the network. Moreover, medium access becomes a challenging problem due to the fact that low-power transceivers are very limited in their sensing capabilities. The first contribution is represented by the Backoff Preamble-based MAC Protocol with Sequential Contention Resolution (BPS-MAC) which is designed to overcome the limitations of low-power transceivers. Two communication issues, namely the Clear Channel Assessment (CCA) delay and the turnaround time, are directly addressed by the protocol. The CCA delay represents the period of time which is required by the transceiver to detect a busy radio channel while the turnaround time specifies the period of time which is required to switch between receive and transmit mode. Standard Carrier Sense Multiple Access (CSMA) protocols do not achieve high performance in terms of packet loss if the traffic is highly correlated due to the fact that the transceiver is not able to sense the medium during the switching phase. Therefore, a node may start to transmit data while another node is already transmitting since it has sensed an idle medium right before it started to switch its transceiver from receive to transmit mode. The BPS-MAC protocol uses a new sequential preamble-based medium access strategy which can be adapted to the hardware capabilities of the transceivers. The protocol achieves a very low packet loss rate even in wireless networks with high node density and event-driven traffic without the need of synchronization. This makes the protocol attractive to applications such as structural health monitoring, where event suppression is not an option. Moreover, acknowledgments or complex retransmission strategies become almost unnecessary since the sequential preamble-based contention resolution mechanism minimizes the collision probability. However, packets can still be lost as a consequence of interference or other issues which affect signal propagation. The second contribution consists of a new routing protocol which is able to quickly detect topology changes without generating a large amount of overhead. The key characteristics of the Statistic-Based Routing (SBR) protocol are high end-to-end reliability (in fixed and mobile networks), load balancing capabilities, a smooth continuous routing metric, quick adaptation to changing network conditions, low processing and memory requirements, low overhead, support of unidirectional links and simplicity. The protocol can establish routes in a hybrid or a proactive mode and uses an adaptive continuous routing metric which makes it very flexible in terms of scalability while maintaining stable routes. The hybrid mode is optimized for low-power WSNs since routes are only established on demand. The difference of the hybrid mode to reactive routing strategies is that routing messages are periodically transmitted to maintain already established routes. However, the protocol stops the transmission of routing messages if no data packets are transmitted for a certain time period in order to minimize the routing overhead and the energy consumption. The proactive mode is designed for high data rate networks which have less energy constraints. In this mode, the protocol periodically transmits routing messages to establish routes in a proactive way even in the absence of data traffic. Thus, nodes in the network can immediately transmit data since the route to the destination is already established in advance. In addition, a new delay-based routing message forwarding strategy is introduced. The forwarding strategy is part of SBR but can also be applied to many routing protocols in order to modify the established topology. The strategy can be used, e.g. in mobile networks, to decrease the packet loss by deferring routing messages with respect to the neighbor change rate. Thus, nodes with a stable neighborhood forward messages faster than nodes within a fast changing neighborhood. As a result, routes are established through nodes with correlated movement which results in fewer topology changes due to higher link durations. N2 - Im Rahmen dieser Arbeit werden leistungsbeschränkende Faktoren von Medium Access Control (MAC) und Routingprotokollen im Kontext von drahtlosen Sensornetzen untersucht. Zunächst werden typische Probleme des Funkkanals diskutiert. Anschließend führen eine Einteilung von MAC Protokollen, sowie eine Gegenüberstellung relevanter Protokolle in die Thematik ein. Daraufhin werden hardwarelimitierende Faktoren und deren Auswirkung auf die Effizienz von Kanalzugriffsprotokollen untersucht. Des Weiteren wird das vom Autor entwickelte Backoff Preamble-based MAC Protokoll (BPS-MAC) vorgestellt, welches auf die limitierten Fähigkeiten sensortypischer Hardware eingeht und für dichte Sensornetze mit korreliertem Datenverkehr optimiert ist. Ein weiterer Schwerpunkt dieser Arbeit stellt das Thema Routing dar. Hier wird ebenfalls mit einer Einteilung der Protokolle in die Thematik eingeführt. Darüber hinaus werden die wichtigsten Aufgaben von Routingprotokollen vorgestellt. Ein Überblick über häufig verwendete Routingmetriken und Routingprotokolle schließen die Einführung in diesen Themenkomplex ab. Abschließend wird das im Rahmen der Dissertation entwickelte Statistic-Based-Routing (SBR) Protokoll vorgestellt, welches ebenfalls für drahtlose Sensornetze optimiert ist. Der letzte Schwerpunkt beschreibt die Problematik der Leistungsbewertung von Routingprotokollen hinsichtlich klassischer Leistungsparameter wie Paketverlust und Verzögerung. Ebenfalls werden weitere Leistungsparameter wie zum Beispiel die vom Nutzer wahrgenommene Netzqualität genauer untersucht. T3 - Würzburger Beiträge zur Leistungsbewertung Verteilter Systeme - 03/10 KW - Routing KW - Drahtloses Sensorsystem KW - Leistungsbewertung KW - Diskrete Simulation KW - MAC KW - Kanalzugriff KW - Medium KW - MAC KW - routing KW - sensor KW - networks KW - simulation Y1 - 2010 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-52870 ER - TY - THES A1 - Klein, Dominik Werner T1 - Design and Evaluation of Components for Future Internet Architectures T1 - Entwurf und Bewertung von Komponenten für zukünftige Internet Architekturen N2 - Die derzeitige Internetarchitektur wurde nicht in einem geplanten Prozess konzipiert und entwickelt, sondern hat vielmehr eine evolutionsartige Entwicklung hinter sich. Auslöser für die jeweiligen Evolutionsschritte waren dabei meist aufstrebende Anwendungen, welche neue Anforderungen an die zugrundeliegende Netzarchitektur gestellt haben. Um diese Anforderungen zu erfüllen, wurden häufig neuartige Dienste oder Protokolle spezifiziert und in die bestehende Architektur integriert. Dieser Prozess ist jedoch meist mit hohem Aufwand verbunden und daher sehr träge, was die Entwicklung und Verbreitung innovativer Dienste beeinträchtigt. Derzeitig diskutierte Konzepte wie Software-Defined Networking (SDN) oder Netzvirtualisierung (NV) werden als eine Möglichkeit angesehen, die Altlasten der bestehenden Internetarchitektur zu lösen. Beiden Konzepten gemein ist die Idee, logische Netze über dem physikalischen Substrat zu betreiben. Diese logischen Netze sind hochdynamisch und können so flexibel an die Anforderungen der jeweiligen Anwendungen angepasst werden. Insbesondere erlaubt das Konzept der Virtualisierung intelligentere Netzknoten, was innovative neue Anwendungsfälle ermöglicht. Ein häufig in diesem Zusammenhang diskutierter Anwendungsfall ist die Mobilität sowohl von Endgeräten als auch von Diensten an sich. Die Mobilität der Dienste wird hierbei ausgenutzt, um die Zugriffsverzögerung oder die belegten Ressourcen im Netz zu reduzieren, indem die Dienste zum Beispiel in für den Nutzer geographisch nahe Datenzentren migriert werden. Neben den reinen Mechanismen bezüglich Dienst- und Endgerätemobilität sind in diesem Zusammenhang auch geeignete Überwachungslösungen relevant, welche die vom Nutzer wahrgenommene Dienstgüte bewerten können. Diese Lösungen liefern wichtige Entscheidungshilfen für die Migration oder überwachen mögliche Effekte der Migration auf die erfahrene Dienstgüte beim Nutzer. Im Falle von Video Streaming ermöglicht ein solcher Anwendungsfall die flexible Anpassung der Streaming Topologie für mobile Nutzer, um so die Videoqualität unabhängig vom Zugangsnetz aufrechterhalten zu können. Im Rahmen dieser Doktorarbeit wird der beschriebene Anwendungsfall am Beispiel einer Video Streaming Anwendung näher analysiert und auftretende Herausforderungen werden diskutiert. Des Weiteren werden Lösungsansätze vorgestellt und bezüglich ihrer Effizienz ausgewertet. Im Detail beschäftigt sich die Arbeit mit der Leistungsanalyse von Mechanismen für die Dienstmobilität und entwickelt eine Architektur zur Optimierung der Dienstmobilität. Im Bereich Endgerätemobilität werden Verbesserungen entwickelt, welche die Latenz zwischen Endgerät und Dienst reduzieren oder die Konnektivität unabhängig vom Zugangsnetz gewährleisten. Im letzten Teilbereich wird eine Lösung zur Überwachung der Videoqualität im Netz entwickelt und bezüglich ihrer Genauigkeit analysiert. N2 - Today’s Internet architecture was not designed from scratch but was driven by new services that emerged during its development. Hence, it is often described as patchwork where additional patches are applied in case new services require modifications to the existing architecture. This process however is rather slow and hinders the development of innovative network services with certain architecture or network requirements. Currently discussed technologies like Software-Defined Networking (SDN) or Network Virtualization (NV) are seen as key enabling technologies to overcome this rigid best effort legacy of the Internet. Both technologies offer the possibility to create virtual networks that accommodate the specific needs of certain services. These logical networks are operated on top of a physical substrate and facilitate flexible network resource allocation as physical resources can be added and removed depending on the current network and load situation. In addition, the clear separation and isolation of networks foster the development of application-aware networks that fulfill the special requirements of emerging applications. A prominent use case that benefits from these extended capabilities of the network is denoted with service component mobility. Services hosted on Virtual Machines (VMs) follow their consuming mobile endpoints, so that access latency as well as consumed network resources are reduced. Especially for applications like video streaming, which consume a large fraction of the available resources, is this an important means to relieve the resource constraints and eventually provide better service quality. Service and endpoint mobility both allow an adaptation of the used paths between an offered service, i.e., video streaming and the consuming users in case the service quality drops due to network problems. To make evidence-based adaptations in case of quality drops, a scalable monitoring component is required that is able to monitor the service quality for video streaming applications with reliable accuracy. This monograph details challenges that arise when deploying a certain service, i.e., video streaming, in a future virtualized network architecture and discusses possible solutions. In particular, this work evaluates the performance of mechanisms enabling service mobility and presents an optimized architecture for service mobility. Concerning endpoint mobility, improvements are developed that reduce the latency between endpoints and consumed services and ensure connectivity regardless of the used mobile access network. In the last part, a network-based video quality monitoring solution is developed and its accuracy is evaluated. T3 - Würzburger Beiträge zur Leistungsbewertung Verteilter Systeme - 01/14 KW - Leistungsbewertung KW - Netzwerkmanagement KW - Virtuelles Netzwerk KW - Mobiles Internet KW - Service Mobility KW - Endpoint Mobility KW - Video Quality Monitoring Y1 - 2014 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-93134 SN - 1432-8801 ER - TY - JOUR A1 - Klemz, Boris A1 - Rote, Günter T1 - Linear-Time Algorithms for Maximum-Weight Induced Matchings and Minimum Chain Covers in Convex Bipartite Graphs JF - Algorithmica N2 - A bipartite graph G=(U,V,E) is convex if the vertices in V can be linearly ordered such that for each vertex u∈U, the neighbors of u are consecutive in the ordering of V. An induced matching H of G is a matching for which no edge of E connects endpoints of two different edges of H. We show that in a convex bipartite graph with n vertices and m weighted edges, an induced matching of maximum total weight can be computed in O(n+m) time. An unweighted convex bipartite graph has a representation of size O(n) that records for each vertex u∈U the first and last neighbor in the ordering of V. Given such a compact representation, we compute an induced matching of maximum cardinality in O(n) time. In convex bipartite graphs, maximum-cardinality induced matchings are dual to minimum chain covers. A chain cover is a covering of the edge set by chain subgraphs, that is, subgraphs that do not contain induced matchings of more than one edge. Given a compact representation, we compute a representation of a minimum chain cover in O(n) time. If no compact representation is given, the cover can be computed in O(n+m) time. All of our algorithms achieve optimal linear running time for the respective problem and model, and they improve and generalize the previous results in several ways: The best algorithms for the unweighted problem versions had a running time of O(n\(^{2}\)) (Brandstädt et al. in Theor. Comput. Sci. 381(1–3):260–265, 2007. https://doi.org/10.1016/j.tcs.2007.04.006). The weighted case has not been considered before. KW - dynamic programming KW - graph algorithm KW - induced matching KW - chain cover KW - convex bipartite graph KW - certifying algorithm Y1 - 2022 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-267876 SN - 1432-0541 VL - 84 IS - 4 ER - TY - JOUR A1 - Koopmann, Tobias A1 - Stubbemann, Maximilian A1 - Kapa, Matthias A1 - Paris, Michael A1 - Buenstorf, Guido A1 - Hanika, Tom A1 - Hotho, Andreas A1 - Jäschke, Robert A1 - Stumme, Gerd T1 - Proximity dimensions and the emergence of collaboration: a HypTrails study on German AI research JF - Scientometrics N2 - Creation and exchange of knowledge depends on collaboration. Recent work has suggested that the emergence of collaboration frequently relies on geographic proximity. However, being co-located tends to be associated with other dimensions of proximity, such as social ties or a shared organizational environment. To account for such factors, multiple dimensions of proximity have been proposed, including cognitive, institutional, organizational, social and geographical proximity. Since they strongly interrelate, disentangling these dimensions and their respective impact on collaboration is challenging. To address this issue, we propose various methods for measuring different dimensions of proximity. We then present an approach to compare and rank them with respect to the extent to which they indicate co-publications and co-inventions. We adapt the HypTrails approach, which was originally developed to explain human navigation, to co-author and co-inventor graphs. We evaluate this approach on a subset of the German research community, specifically academic authors and inventors active in research on artificial intelligence (AI). We find that social proximity and cognitive proximity are more important for the emergence of collaboration than geographic proximity. KW - collaboration KW - dimensions of proximity KW - co-authorships KW - co-inventorships KW - embedding techniques Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-269831 SN - 1588-2861 VL - 126 IS - 12 ER - TY - THES A1 - Kosub, Sven T1 - Complexity and Partitions T1 - Komplexität von Partitionen N2 - Computational complexity theory usually investigates the complexity of sets, i.e., the complexity of partitions into two parts. But often it is more appropriate to represent natural problems by partitions into more than two parts. A particularly interesting class of such problems consists of classification problems for relations. For instance, a binary relation R typically defines a partitioning of the set of all pairs (x,y) into four parts, classifiable according to the cases where R(x,y) and R(y,x) hold, only R(x,y) or only R(y,x) holds or even neither R(x,y) nor R(y,x) is true. By means of concrete classification problems such as Graph Embedding or Entailment (for propositional logic), this thesis systematically develops tools, in shape of the boolean hierarchy of NP-partitions and its refinements, for the qualitative analysis of the complexity of partitions generated by NP-relations. The Boolean hierarchy of NP-partitions is introduced as a generalization of the well-known and well-studied Boolean hierarchy (of sets) over NP. Whereas the latter hierarchy has a very simple structure, the situation is much more complicated for the case of partitions into at least three parts. To get an idea of this hierarchy, alternative descriptions of the partition classes are given in terms of finite, labeled lattices. Based on these characterizations the Embedding Conjecture is established providing the complete information on the structure of the hierarchy. This conjecture is supported by several results. A natural extension of the Boolean hierarchy of NP-partitions emerges from the lattice-characterization of its classes by considering partition classes generated by finite, labeled posets. It turns out that all significant ideas translate from the case of lattices. The induced refined Boolean hierarchy of NP-partitions enables us more accuratly capturing the complexity of certain relations (such as Graph Embedding) and a description of projectively closed partition classes. N2 - Die klassische Komplexitätstheorie untersucht in erster Linie die Komplexität von Mengen, d.h. von Zerlegungen (Partitionen) einer Grundmenge in zwei Teile. Häufig werden aber natürliche Fragestellungen viel angemessener durch Zerlegungen in mehr als zwei Teile abgebildet. Eine besonders interessante Klasse solcher Fragestellungen sind Klassifikationsprobleme für Relationen. Zum Beispiel definiert eine Binärrelation R typischerweise eine Zerlegung der Menge aller Paare (x,y) in vier Teile, klassifizierbar danach, ob R(x,y) und R(y,x), R(x,y) aber nicht R(y,x), nicht R(x,y) aber dafür R(y,x) oder weder R(x,y) noch R(y,x) gilt. Anhand konkreter Klassifikationsprobleme, wie zum Beispiel der Einbettbarkeit von Graphen und der Folgerbarkeit für aussagenlogische Formeln, werden in der Dissertation Instrumente für eine qualitative Analyse der Komplexität von Partitionen, die von NP-Relationen erzeugt werden, in Form der Booleschen Hierarchie der NP-Partitionen und ihrer Erweiterungen systematisch entwickelt. Die Boolesche Hierarchie der NP-Partitionen wird als Verallgemeinerung der bereits bekannten und wohluntersuchten Boolesche Hierarchie über NP eingeführt. Während die letztere Hierarchie eine sehr einfache Struktur aufweist, stellt sich die Boolesche Hierarchie der NP-Partitionen im Falle von Zerlegungen in mindestens 3 Teile als sehr viel komplizierter heraus. Um einen Überblick über diese Hierarchien zu erlangen, werden alternative Beschreibungen der Klassen der Hierarchien mittels endlicher, bewerteter Verbände angegeben. Darauf aufbauend wird die Einbettungsvermutung aufgestellt, die uns die vollständige Information über die Struktur der Hierarchie liefert. Diese Vermutung wird mit verschiedene Resultaten untermauert. Eine Erweiterung der Booleschen Hierarchie der NP-Partitionen ergibt sich auf natürliche Weise aus der Charakterisierung ihrer Klassen durch Verbände. Dazu werden Klassen betrachtet, die von endlichen, bewerteten Halbordnungen erzeugt werden. Es zeigt sich, dass die wesentlichen Konzepte vom Verbandsfall übertragen werden können. Die entstehende Verfeinerung der Booleschen Hierarchie der NP-Partitionen ermöglicht die exaktere Analyse der Komplexität bestimmter Relationen (wie zum Beispiel der Einbettbarkeit von Graphen) und die Beschreibung projektiv abgeschlossener Partitionenklassen. KW - Partition KW - Boolesche Hierarchie KW - Komplexitätsklasse NP KW - Theoretische Informatik KW - Komplexitätstheorie KW - NP KW - Boolesche Hierarchie KW - Partitionen KW - Verbände KW - Halbordnungen KW - Theoretical computer science KW - computational complexity KW - NP KW - Boolean hierarchy KW - partitions KW - lattices KW - posets Y1 - 2001 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-2808 ER - TY - RPRT A1 - Kounev, Samuel A1 - Brosig, Fabian A1 - Huber, Nikolaus T1 - The Descartes Modeling Language N2 - This technical report introduces the Descartes Modeling Language (DML), a new architecture-level modeling language for modeling Quality-of-Service (QoS) and resource management related aspects of modern dynamic IT systems, infrastructures and services. DML is designed to serve as a basis for self-aware resource management during operation ensuring that system QoS requirements are continuously satisfied while infrastructure resources are utilized as efficiently as possible. KW - Ressourcenmanagement KW - Software Engineering KW - Resource and Performance Management KW - Software Performance Engineering KW - Software Performance Modeling KW - Performance Management KW - Quality-of-Service Y1 - 2014 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-104887 ER - TY - JOUR A1 - Kraft, Robin A1 - Birk, Ferdinand A1 - Reichert, Manfred A1 - Deshpande, Aniruddha A1 - Schlee, Winfried A1 - Langguth, Berthold A1 - Baumeister, Harald A1 - Probst, Thomas A1 - Spiliopoulou, Myra A1 - Pryss, Rüdiger T1 - Efficient processing of geospatial mHealth data using a scalable crowdsensing platform JF - Sensors N2 - Smart sensors and smartphones are becoming increasingly prevalent. Both can be used to gather environmental data (e.g., noise). Importantly, these devices can be connected to each other as well as to the Internet to collect large amounts of sensor data, which leads to many new opportunities. In particular, mobile crowdsensing techniques can be used to capture phenomena of common interest. Especially valuable insights can be gained if the collected data are additionally related to the time and place of the measurements. However, many technical solutions still use monolithic backends that are not capable of processing crowdsensing data in a flexible, efficient, and scalable manner. In this work, an architectural design was conceived with the goal to manage geospatial data in challenging crowdsensing healthcare scenarios. It will be shown how the proposed approach can be used to provide users with an interactive map of environmental noise, allowing tinnitus patients and other health-conscious people to avoid locations with harmful sound levels. Technically, the shown approach combines cloud-native applications with Big Data and stream processing concepts. In general, the presented architectural design shall serve as a foundation to implement practical and scalable crowdsensing platforms for various healthcare scenarios beyond the addressed use case. KW - mHealth KW - crowdsensing KW - tinnitus KW - geospatial data KW - cloud-native KW - stream processing KW - scalability KW - architectural design Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-207826 SN - 1424-8220 VL - 20 IS - 12 ER - TY - JOUR A1 - Kraft, Robin A1 - Reichert, Manfred A1 - Pryss, Rüdiger T1 - Towards the interpretation of sound measurements from smartphones collected with mobile crowdsensing in the healthcare domain: an experiment with Android devices JF - Sensors N2 - The ubiquity of mobile devices fosters the combined use of ecological momentary assessments (EMA) and mobile crowdsensing (MCS) in the field of healthcare. This combination not only allows researchers to collect ecologically valid data, but also to use smartphone sensors to capture the context in which these data are collected. The TrackYourTinnitus (TYT) platform uses EMA to track users' individual subjective tinnitus perception and MCS to capture an objective environmental sound level while the EMA questionnaire is filled in. However, the sound level data cannot be used directly among the different smartphones used by TYT users, since uncalibrated raw values are stored. This work describes an approach towards making these values comparable. In the described setting, the evaluation of sensor measurements from different smartphone users becomes increasingly prevalent. Therefore, the shown approach can be also considered as a more general solution as it not only shows how it helped to interpret TYT sound level data, but may also stimulate other researchers, especially those who need to interpret sensor data in a similar setting. Altogether, the approach will show that measuring sound levels with mobile devices is possible in healthcare scenarios, but there are many challenges to ensuring that the measured values are interpretable. KW - mHealth KW - crowdsensing KW - tinnitus KW - noise measurement KW - environmental sound Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-252246 SN - 1424-8220 VL - 22 IS - 1 ER - TY - THES A1 - Krenzer, Adrian T1 - Machine learning to support physicians in endoscopic examinations with a focus on automatic polyp detection in images and videos T1 - Maschinelles Lernen zur Unterstützung von Ärzten bei endoskopischen Untersuchungen mit Schwerpunkt auf der automatisierten Polypenerkennung in Bildern und Videos N2 - Deep learning enables enormous progress in many computer vision-related tasks. Artificial Intel- ligence (AI) steadily yields new state-of-the-art results in the field of detection and classification. Thereby AI performance equals or exceeds human performance. Those achievements impacted many domains, including medical applications. One particular field of medical applications is gastroenterology. In gastroenterology, machine learning algorithms are used to assist examiners during interventions. One of the most critical concerns for gastroenterologists is the development of Colorectal Cancer (CRC), which is one of the leading causes of cancer-related deaths worldwide. Detecting polyps in screening colonoscopies is the essential procedure to prevent CRC. Thereby, the gastroenterologist uses an endoscope to screen the whole colon to find polyps during a colonoscopy. Polyps are mucosal growths that can vary in severity. This thesis supports gastroenterologists in their examinations with automated detection and clas- sification systems for polyps. The main contribution is a real-time polyp detection system. This system is ready to be installed in any gastroenterology practice worldwide using open-source soft- ware. The system achieves state-of-the-art detection results and is currently evaluated in a clinical trial in four different centers in Germany. The thesis presents two additional key contributions: One is a polyp detection system with ex- tended vision tested in an animal trial. Polyps often hide behind folds or in uninvestigated areas. Therefore, the polyp detection system with extended vision uses an endoscope assisted by two additional cameras to see behind those folds. If a polyp is detected, the endoscopist receives a vi- sual signal. While the detection system handles the additional two camera inputs, the endoscopist focuses on the main camera as usual. The second one are two polyp classification models, one for the classification based on shape (Paris) and the other on surface and texture (NBI International Colorectal Endoscopic (NICE) classification). Both classifications help the endoscopist with the treatment of and the decisions about the detected polyp. The key algorithms of the thesis achieve state-of-the-art performance. Outstandingly, the polyp detection system tested on a highly demanding video data set shows an F1 score of 90.25 % while working in real-time. The results exceed all real-time systems in the literature. Furthermore, the first preliminary results of the clinical trial of the polyp detection system suggest a high Adenoma Detection Rate (ADR). In the preliminary study, all polyps were detected by the polyp detection system, and the system achieved a high usability score of 96.3 (max 100). The Paris classification model achieved an F1 score of 89.35 % which is state-of-the-art. The NICE classification model achieved an F1 score of 81.13 %. Furthermore, a large data set for polyp detection and classification was created during this thesis. Therefore a fast and robust annotation system called Fast Colonoscopy Annotation Tool (FastCAT) was developed. The system simplifies the annotation process for gastroenterologists. Thereby the i gastroenterologists only annotate key parts of the endoscopic video. Afterward, those video parts are pre-labeled by a polyp detection AI to speed up the process. After the AI has pre-labeled the frames, non-experts correct and finish the annotation. This annotation process is fast and ensures high quality. FastCAT reduces the overall workload of the gastroenterologist on average by a factor of 20 compared to an open-source state-of-art annotation tool. N2 - Deep Learning ermöglicht enorme Fortschritte bei vielen Aufgaben im Bereich der Computer Vision. Künstliche Intelligenz (KI) liefert ständig neue Spitzenergebnisse im Bereich der Erkennung und Klassifizierung. Dabei erreicht oder übertrifft die Leistung von KI teilweise die menschliche Leistung. Diese Errungenschaften wirken sich auf viele Bereiche aus, darunter auch auf medizinische Anwendungen. Ein besonderer Bereich der medizinischen Anwendungen ist die Gastroenterologie. In der Gastroenterologie werden Algorithmen des maschinellen Lernens eingesetzt, um den Untersucher bei medizinischen Eingriffen zu unterstützen. Eines der größten Probleme für Gastroenterologen ist die Entwicklung von Darmkrebs, die weltweit eine der häufigsten krebsbedingten Todesursachen ist. Die Erkennung von Polypen bei Darmspiegelungen ist das wichtigste Verfahren zur Vorbeugung von Darmkrebs. Dabei untersucht der Gastroenterologe den Dickdarm im Rahmen einer Koloskopie, um z.B. Polypen zu finden. Polypen sind Schleimhautwucherungen, die unterschiedlich stark ausgeprägt sein können. Diese Arbeit unterstützt Gastroenterologen bei ihren Untersuchungen mit automatischen Erkennungssystemen und Klassifizierungssystemen für Polypen. Der Hauptbeitrag ist ein Echtzeitpolypenerkennungssystem. Dieses System kann in jeder gastroenterologischen Praxis weltweit mit Open- Source-Software installiert werden. Das System erzielt Erkennungsergebnisse auf dem neusten Stand der Technik und wird derzeit in einer klinischen Studie in vier verschiedenen Praxen in Deutschland evaluiert. In dieser Arbeit werden zwei weitere wichtige Beiträge vorgestellt: Zum einen ein Polypenerkennungssystem mit erweiterter Sicht, das in einem Tierversuch getestet wurde. Polypen verstecken sich oft hinter Falten oder in nicht untersuchten Bereichen. Daher verwendet das Polypenerkennungssystem mit erweiterter Sicht ein Endoskop, das von zwei zusätzlichen Kameras unterstützt wird, um hinter diese Falten zu sehen. Wenn ein Polyp entdeckt wird, erhält der Endoskopiker ein visuelles Signal. Während das Erkennungssystem die beiden zusätzlichen Kameraeingaben verarbeitet, konzentriert sich der Endoskopiker wie gewohnt auf die Hauptkamera. Das zweite sind zwei Polypenklassifizierungsmodelle, eines für die Klassifizierung anhand der Form (Paris) und das andere anhand der Oberfläche und Textur (NICE-Klassifizierung). Beide Klassifizierungen helfen dem Endoskopiker bei der Behandlung und Entscheidung über den erkannten Polypen. Die Schlüsselalgorithmen der Dissertation erreichen eine Leistung, die dem neuesten Stand der Technik entspricht. Herausragend ist, dass das auf einem anspruchsvollen Videodatensatz getestete Polypenerkennungssystem einen F1-Wert von 90,25 % aufweist, während es in Echtzeit arbeitet. Die Ergebnisse übertreffen alle Echtzeitsysteme für Polypenerkennung in der Literatur. Darüber hinaus deuten die ersten vorläufigen Ergebnisse einer klinischen Studie des Polypenerkennungssystems auf eine hohe Adenomdetektionsrate ADR hin. In dieser Studie wurden alle Polypen durch das Polypenerkennungssystem erkannt, und das System erreichte einen hohe Nutzerfreundlichkeit von 96,3 (maximal 100). Bei der automatischen Klassifikation von Polypen basierend auf der Paris Klassifikations erreichte das in dieser Arbeit entwickelte System einen F1-Wert von 89,35 %, was dem neuesten Stand der Technik entspricht. Das NICE-Klassifikationsmodell erreichte eine F1- Wert von 81,13 %. Darüber hinaus wurde im Rahmen dieser Arbeit ein großer Datensatz zur Polypenerkennung und -klassifizierung erstellt. Dafür wurde ein schnelles und robustes Annotationssystem namens FastCAT entwickelt. Das System vereinfacht den Annotationsprozess für Gastroenterologen. Die Gastroenterologen annotieren dabei nur die wichtigsten Teile des endoskopischen Videos. Anschließend werden diese Videoteile von einer Polypenerkennungs-KI vorverarbeitet, um den Prozess zu beschleunigen. Nachdem die KI die Bilder vorbeschriftet hat, korrigieren und vervollständigen Nicht-Experten die Annotationen. Dieser Annotationsprozess ist schnell und gewährleistet eine hohe Qualität. FastCAT reduziert die Gesamtarbeitsbelastung des Gastroenterologen im Durchschnitt um den Faktor 20 im Vergleich zu einem Open-Source-Annotationstool auf dem neuesten Stand der Technik. KW - Deep Learning KW - Maschinelles Lernen KW - Maschinelles Sehen KW - Machine Learning KW - Object Detection KW - Medical Image Analysis KW - Computer Vision KW - Gastroenterologische Endoskopie KW - Polypektomie Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-319119 ER - TY - JOUR A1 - Krenzer, Adrian A1 - Heil, Stefan A1 - Fitting, Daniel A1 - Matti, Safa A1 - Zoller, Wolfram G. A1 - Hann, Alexander A1 - Puppe, Frank T1 - Automated classification of polyps using deep learning architectures and few-shot learning JF - BMC Medical Imaging N2 - Background Colorectal cancer is a leading cause of cancer-related deaths worldwide. The best method to prevent CRC is a colonoscopy. However, not all colon polyps have the risk of becoming cancerous. Therefore, polyps are classified using different classification systems. After the classification, further treatment and procedures are based on the classification of the polyp. Nevertheless, classification is not easy. Therefore, we suggest two novel automated classifications system assisting gastroenterologists in classifying polyps based on the NICE and Paris classification. Methods We build two classification systems. One is classifying polyps based on their shape (Paris). The other classifies polyps based on their texture and surface patterns (NICE). A two-step process for the Paris classification is introduced: First, detecting and cropping the polyp on the image, and secondly, classifying the polyp based on the cropped area with a transformer network. For the NICE classification, we design a few-shot learning algorithm based on the Deep Metric Learning approach. The algorithm creates an embedding space for polyps, which allows classification from a few examples to account for the data scarcity of NICE annotated images in our database. Results For the Paris classification, we achieve an accuracy of 89.35 %, surpassing all papers in the literature and establishing a new state-of-the-art and baseline accuracy for other publications on a public data set. For the NICE classification, we achieve a competitive accuracy of 81.13 % and demonstrate thereby the viability of the few-shot learning paradigm in polyp classification in data-scarce environments. Additionally, we show different ablations of the algorithms. Finally, we further elaborate on the explainability of the system by showing heat maps of the neural network explaining neural activations. Conclusion Overall we introduce two polyp classification systems to assist gastroenterologists. We achieve state-of-the-art performance in the Paris classification and demonstrate the viability of the few-shot learning paradigm in the NICE classification, addressing the prevalent data scarcity issues faced in medical machine learning. KW - machine learning KW - deep learning KW - endoscopy KW - gastroenterology KW - automation KW - image classification KW - transformer KW - deep metric learning KW - few-shot learning Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-357465 VL - 23 ER - TY - JOUR A1 - Krenzer, Adrian A1 - Makowski, Kevin A1 - Hekalo, Amar A1 - Fitting, Daniel A1 - Troya, Joel A1 - Zoller, Wolfram G. A1 - Hann, Alexander A1 - Puppe, Frank T1 - Fast machine learning annotation in the medical domain: a semi-automated video annotation tool for gastroenterologists JF - BioMedical Engineering OnLine N2 - Background Machine learning, especially deep learning, is becoming more and more relevant in research and development in the medical domain. For all the supervised deep learning applications, data is the most critical factor in securing successful implementation and sustaining the progress of the machine learning model. Especially gastroenterological data, which often involves endoscopic videos, are cumbersome to annotate. Domain experts are needed to interpret and annotate the videos. To support those domain experts, we generated a framework. With this framework, instead of annotating every frame in the video sequence, experts are just performing key annotations at the beginning and the end of sequences with pathologies, e.g., visible polyps. Subsequently, non-expert annotators supported by machine learning add the missing annotations for the frames in-between. Methods In our framework, an expert reviews the video and annotates a few video frames to verify the object’s annotations for the non-expert. In a second step, a non-expert has visual confirmation of the given object and can annotate all following and preceding frames with AI assistance. After the expert has finished, relevant frames will be selected and passed on to an AI model. This information allows the AI model to detect and mark the desired object on all following and preceding frames with an annotation. Therefore, the non-expert can adjust and modify the AI predictions and export the results, which can then be used to train the AI model. Results Using this framework, we were able to reduce workload of domain experts on average by a factor of 20 on our data. This is primarily due to the structure of the framework, which is designed to minimize the workload of the domain expert. Pairing this framework with a state-of-the-art semi-automated AI model enhances the annotation speed further. Through a prospective study with 10 participants, we show that semi-automated annotation using our tool doubles the annotation speed of non-expert annotators compared to a well-known state-of-the-art annotation tool. Conclusion In summary, we introduce a framework for fast expert annotation for gastroenterologists, which reduces the workload of the domain expert considerably while maintaining a very high annotation quality. The framework incorporates a semi-automated annotation system utilizing trained object detection models. The software and framework are open-source. KW - object detection KW - machine learning KW - deep learning KW - annotation KW - endoscopy KW - gastroenterology KW - automation Y1 - 2022 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-300231 VL - 21 IS - 1 ER - TY - JOUR A1 - Krueger, Beate A1 - Friedrich, Torben A1 - Förster, Frank A1 - Bernhardt, Jörg A1 - Gross, Roy A1 - Dandekar, Thomas T1 - Different evolutionary modifications as a guide to rewire two-component systems JF - Bioinformatics and Biology Insights N2 - Two-component systems (TCS) are short signalling pathways generally occurring in prokaryotes. They frequently regulate prokaryotic stimulus responses and thus are also of interest for engineering in biotechnology and synthetic biology. The aim of this study is to better understand and describe rewiring of TCS while investigating different evolutionary scenarios. Based on large-scale screens of TCS in different organisms, this study gives detailed data, concrete alignments, and structure analysis on three general modification scenarios, where TCS were rewired for new responses and functions: (i) exchanges in the sequence within single TCS domains, (ii) exchange of whole TCS domains; (iii) addition of new components modulating TCS function. As a result, the replacement of stimulus and promotor cassettes to rewire TCS is well defined exploiting the alignments given here. The diverged TCS examples are non-trivial and the design is challenging. Designed connector proteins may also be useful to modify TCS in selected cases. KW - histidine kinase KW - connector KW - Mycoplasma KW - engineering KW - promoter KW - sensor KW - response regulator KW - synthetic biology KW - sequence alignment Y1 - 2012 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-123647 N1 - This is an open access article. Unrestricted non-commercial use is permitted provided the original work is properly cited. VL - 6 ER - TY - JOUR A1 - Krupitzer, Christian A1 - Eberhardinger, Benedikt A1 - Gerostathopoulos, Ilias A1 - Raibulet, Claudia T1 - Introduction to the special issue “Applications in Self-Aware Computing Systems and their Evaluation” JF - Computers N2 - The joint 1st Workshop on Evaluations and Measurements in Self-Aware Computing Systems (EMSAC 2019) and Workshop on Self-Aware Computing (SeAC) was held as part of the FAS* conference alliance in conjunction with the 16th IEEE International Conference on Autonomic Computing (ICAC) and the 13th IEEE International Conference on Self-Adaptive and Self-Organizing Systems (SASO) in Umeå, Sweden on 20 June 2019. The goal of this one-day workshop was to bring together researchers and practitioners from academic environments and from the industry to share their solutions, ideas, visions, and doubts in self-aware computing systems in general and in the evaluation and measurements of such systems in particular. The workshop aimed to enable discussions, partnerships, and collaborations among the participants. This special issue follows the theme of the workshop. It contains extended versions of workshop presentations as well as additional contributions. KW - self-aware computing systems KW - quality evaluation KW - measurements KW - quality assurance KW - autonomous KW - self-adaptive KW - self-managing systems Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-203439 SN - 2073-431X VL - 9 IS - 1 ER - TY - JOUR A1 - Kuhn, Joachim A1 - Gripp, Tatjana A1 - Flieder, Tobias A1 - Dittrich, Marcus A1 - Hendig, Doris A1 - Busse, Jessica A1 - Knabbe, Cornelius A1 - Birschmann, Ingvild T1 - UPLC-MRM Mass Spectrometry Method for Measurement of the Coagulation Inhibitors Dabigatran and Rivaroxaban in Human Plasma and Its Comparison with Functional Assays JF - PLOS ONE N2 - Introduction The fast, precise, and accurate measurement of the new generation of oral anticoagulants such as dabigatran and rivaroxaban in patients' plasma my provide important information in different clinical circumstances such as in the case of suspicion of overdose, when patients switch from existing oral anticoagulant, in patients with hepatic or renal impairment, by concomitant use of interaction drugs, or to assess anticoagulant concentration in patients' blood before major surgery. Methods Here, we describe a quick and precise method to measure the coagulation inhibitors dabigatran and rivaroxaban using ultra-performance liquid chromatography electrospray ionization-tandem mass spectrometry in multiple reactions monitoring (MRM) mode (UPLC-MRM MS). Internal standards (ISs) were added to the sample and after protein precipitation; the sample was separated on a reverse phase column. After ionization of the analytes the ions were detected using electrospray ionization-tandem mass spectrometry. Run time was 2.5 minutes per injection. Ion suppression was characterized by means of post-column infusion. Results The calibration curves of dabigatran and rivaroxaban were linear over the working range between 0.8 and 800 mu g/L (r > 0.99). Limits of detection (LOD) in the plasma matrix were 0.21 mu g/L for dabigatran and 0.34 mu g/L for rivaroxaban, and lower limits of quantification (LLOQ) in the plasma matrix were 0.46 mu g/L for dabigatran and 0.54 mu g/L for rivaroxaban. The intraassay coefficients of variation (CVs) for dabigatran and rivaroxaban were < 4% and 6%; respectively, the interassay CVs were < 6% for dabigatran and < 9% for rivaroxaban. Inaccuracy was < 5% for both substances. The mean recovery was 104.5% (range 83.8-113.0%) for dabigatran and 87.0%(range 73.6-105.4%) for rivaroxaban. No significant ion suppressions were detected at the elution times of dabigatran or rivaroxaban. Both coagulation inhibitors were stable in citrate plasma at -20 degrees C, 4 degrees C and even at RT for at least one week. A method comparison between our UPLC-MRM MS method, the commercially available automated Direct Thrombin Inhibitor assay (DTI assay) for dabigatran measurement from CoaChrom Diagnostica, as well as the automated anti-Xa assay for rivaroxaban measurement from Chromogenix both performed by ACL-TOP showed a high degree of correlation. However, UPLC-MRM MS measurement of dabigatran and rivaroxaban has a much better selectivity than classical functional assays measuring activities of various coagulation factors which are susceptible to interference by other coagulant drugs. Conclusions Overall, we developed and validated a sensitive and specific UPLC-MRM MS assay for the quick and specific measurement of dabigatran and rivaroxaban in human plasma. KW - LC-MS/MS KW - validation KW - serum KW - quantification KW - apixaban KW - diagnostic accuracy KW - performance liquid chromatography KW - factor XA inhibitor KW - direct oral anticoagulants KW - direct thrombin inhibitor Y1 - 2015 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-136023 VL - 10 IS - 12 ER - TY - JOUR A1 - Kunz, Meik A1 - Liang, Chunguang A1 - Nilla, Santosh A1 - Cecil, Alexander A1 - Dandekar, Thomas T1 - The drug-minded protein interaction database (DrumPID) for efficient target analysis and drug development JF - Database N2 - The drug-minded protein interaction database (DrumPID) has been designed to provide fast, tailored information on drugs and their protein networks including indications, protein targets and side-targets. Starting queries include compound, target and protein interactions and organism-specific protein families. Furthermore, drug name, chemical structures and their SMILES notation, affected proteins (potential drug targets), organisms as well as diseases can be queried including various combinations and refinement of searches. Drugs and protein interactions are analyzed in detail with reference to protein structures and catalytic domains, related compound structures as well as potential targets in other organisms. DrumPID considers drug functionality, compound similarity, target structure, interactome analysis and organismic range for a compound, useful for drug development, predicting drug side-effects and structure–activity relationships. KW - drug-minded protein KW - database Y1 - 2016 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-147369 VL - 2016 ER - TY - JOUR A1 - Landeck, Maximilian A1 - Alvarez Igarzábal, Federico A1 - Unruh, Fabian A1 - Habenicht, Hannah A1 - Khoshnoud, Shiva A1 - Wittmann, Marc A1 - Lugrin, Jean-Luc A1 - Latoschik, Marc Erich T1 - Journey through a virtual tunnel: Simulated motion and its effects on the experience of time JF - Frontiers in Virtual Reality N2 - This paper examines the relationship between time and motion perception in virtual environments. Previous work has shown that the perception of motion can affect the perception of time. We developed a virtual environment that simulates motion in a tunnel and measured its effects on the estimation of the duration of time, the speed at which perceived time passes, and the illusion of self-motion, also known as vection. When large areas of the visual field move in the same direction, vection can occur; observers often perceive this as self-motion rather than motion of the environment. To generate different levels of vection and investigate its effects on time perception, we developed an abstract procedural tunnel generator. The generator can simulate different speeds and densities of tunnel sections (visibly distinguishable sections that form the virtual tunnel), as well as the degree of embodiment of the user avatar (with or without virtual hands). We exposed participants to various tunnel simulations with different durations, speeds, and densities in a remote desktop and a virtual reality (VR) laboratory study. Time passed subjectively faster under high-speed and high-density conditions in both studies. The experience of self-motion was also stronger under high-speed and high-density conditions. Both studies revealed a significant correlation between the perceived passage of time and perceived self-motion. Subjects in the virtual reality study reported a stronger self-motion experience, a faster perceived passage of time, and shorter time estimates than subjects in the desktop study. Our results suggest that a virtual tunnel simulation can manipulate time perception in virtual reality. We will explore these results for the development of virtual reality applications for therapeutic approaches in our future work. This could be particularly useful in treating disorders like depression, autism, and schizophrenia, which are known to be associated with distortions in time perception. For example, the tunnel could be therapeutically applied by resetting patients’ time perceptions by exposing them to the tunnel under different conditions, such as increasing or decreasing perceived time. KW - passage of time KW - illusion of self-motion KW - vection KW - virtual tunnel KW - therapeutic application KW - virtual reality KW - extended reality (XR) Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-301519 SN - 2673-4192 VL - 3 ER - TY - JOUR A1 - Latoschik, Marc Erich A1 - Wienrich, Carolin T1 - Congruence and plausibility, not presence: pivotal conditions for XR experiences and effects, a novel approach JF - Frontiers in Virtual Reality N2 - Presence is often considered the most important quale describing the subjective feeling of being in a computer-generated and/or computer-mediated virtual environment. The identification and separation of orthogonal presence components, i.e., the place illusion and the plausibility illusion, has been an accepted theoretical model describing Virtual Reality (VR) experiences for some time. This perspective article challenges this presence-oriented VR theory. First, we argue that a place illusion cannot be the major construct to describe the much wider scope of virtual, augmented, and mixed reality (VR, AR, MR: or XR for short). Second, we argue that there is no plausibility illusion but merely plausibility, and we derive the place illusion caused by the congruent and plausible generation of spatial cues and similarly for all the current model’s so-defined illusions. Finally, we propose congruence and plausibility to become the central essential conditions in a novel theoretical model describing XR experiences and effects. KW - XR KW - experience KW - presence KW - congruence KW - plausibility KW - coherence KW - theory KW - prediction Y1 - 2022 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-284787 SN - 2673-4192 VL - 3 ER - TY - RPRT A1 - Le, Duy Thanh A1 - Großmann, Marcel A1 - Krieger, Udo R. T1 - Cloudless Resource Monitoring in a Fog Computing System Enabled by an SDN/NFV Infrastructure T2 - Würzburg Workshop on Next-Generation Communication Networks (WueWoWas'22) N2 - Today’s advanced Internet-of-Things applications raise technical challenges on cloud, edge, and fog computing. The design of an efficient, virtualized, context-aware, self-configuring orchestration system of a fog computing system constitutes a major development effort within this very innovative area of research. In this paper we describe the architecture and relevant implementation aspects of a cloudless resource monitoring system interworking with an SDN/NFV infrastructure. It realizes the basic monitoring component of the fundamental MAPE-K principles employed in autonomic computing. Here we present the hierarchical layering and functionality within the underlying fog nodes to generate a working prototype of an intelligent, self-managed orchestrator for advanced IoT applications and services. The latter system has the capability to monitor automatically various performance aspects of the resource allocation among multiple hosts of a fog computing system interconnected by SDN. KW - Datennetz KW - fog computing KW - SDN/NVF KW - container virtualization KW - autonomic orchestration KW - docker Y1 - 2022 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-280723 ER - TY - THES A1 - Lehrieder, Frank T1 - Performance Evaluation and Optimization of Content Distribution using Overlay Networks T1 - Leistungsbewertung und Optimierung von Overlay Netzwerken zum Verteilen großer Datenmengen N2 - The work presents a performance evaluation and optimization of so-called overlay networks for content distribution in the Internet. Chapter 1 describes the importance which have such networks in today's Internet, for example, for the transmission of video content. The focus of this work is on overlay networks based on the peer-to-peer principle. These are characterized by the fact that users who download content, also contribute to the distribution process by sharing parts of the data to other users. This enables efficient content distribution because each user not only consumes resources in the system, but also provides its own resources. Chapter 2 of the monograph contains a detailed description of the functionality of today's most popular overlay network BitTorrent. It explains the various components and their interaction. This is followed by an illustration of why such overlay networks for Internet service providers (ISPs) are problematic. The reason lies in the large amount of inter-ISP traffic that is produced by these overlay networks. Since this inter-ISP traffic leads to high costs for ISPs, they try to reduce it by improved mechanisms for overlay networks. One optimization approach is the use of topology awareness within the overlay networks. It provides users of the overlay networks with information about the underlying physical network topology. This allows them to avoid inter-ISP traffic by exchanging data preferrentially with other users that are connected to the same ISP. Another approach to save inter-ISP traffic is caching. In this case the ISP provides additional computers in its network, called caches, which store copies of popular content. The users of this ISP can then obtain such content from the cache. This prevents that the content must be retrieved from locations outside of the ISP's network, and saves costly inter-ISP traffic in this way. In the third chapter of the thesis, the results of a comprehensive measurement study of overlay networks, which can be found in today's Internet, are presented. After a short description of the measurement methodology, the results of the measurements are described. These results contain data on a variety of characteristics of current P2P overlay networks in the Internet. These include the popularity of content, i.e., how many users are interested in specific content, the evolution of the popularity and the size of the files. The distribution of users within the Internet is investigated in detail. Special attention is given to the number of users that exchange a particular file within the same ISP. On the basis of these measurement results, an estimation of the traffic savings that can achieved by topology awareness is derived. This new estimation is of scientific and practical importance, since it is not limited to individual ISPs and files, but considers the whole Internet and the total amount of data exchanged in overlay networks. Finally, the characteristics of regional content are considered, in which the popularity is limited to certain parts of the Internet. This is for example the case of videos in German, Italian or French language. Chapter 4 of the thesis is devoted to the optimization of overlay networks for content distribution through caching. It presents a deterministic flow model that describes the influence of caches. On the basis of this model, it derives an estimate of the inter-ISP traffic that is generated by an overlay network, and which part can be saved by caches. The results show that the influence of the cache depends on the structure of the overlay networks, and that caches can also lead to an increase in inter-ISP traffic under certain circumstances. The described model is thus an important tool for ISPs to decide for which overlay networks caches are useful and to dimension them. Chapter 5 summarizes the content of the work and emphasizes the importance of the findings. In addition, it explains how the findings can be applied to the optimization of future overlay networks. Special attention is given to the growing importance of video-on-demand and real-time video transmissions. N2 - Die Arbeit beschäftigt sich mit der Leistungsbewertung und Optimierung von sogenannten Overlay-Netzwerken zum Verteilen von großen Datenmengen im Internet. Im Kapitel 1 der Arbeit wird die große Bedeutung erläutert, die solche Netzwerke im heutigen Internet haben, beispielsweise für die Übertragung von Video-Inhalten. Im Fokus der Arbeit liegen Overlay-Netzwerke, die auf dem Peer-to-peer Prinzip basieren. Diese zeichnen sich dadurch aus, dass Nutzer, die Inhalte herunterladen, auch gleichzeitig an dem Verteilprozess teilnehmen, indem sie Teile der Daten an andere Nutzer weitergeben. Dies ermöglicht eine effiziente Verteilung der Daten, weil jeder Nutzer nicht nur Ressourcen im System belegt, sondern auch eigene Ressourcen einbringt. Kapitel 2 der Arbeit enthält eine detaillierte Beschreibung der Funktionsweise des heute populärsten Overlay-Netzwerks BitTorrent. Es werden die einzelnen Komponenten erläutert und deren Zusammenspiel erklärt. Darauf folgt eine Darstellung, warum solche Overlay-Netzwerke für Internet-Anbieter (Internet service provider, ISP) problematisch sind. Der Grund dafür liegt in der großen Menge an Inter-ISP Verkehr, den diese Overlays erzeugen. Da solcher Inter-ISP Verkehr zu hohen Kosten für ISPs führt, versuchen diese den Inter-ISP Verkehr zu reduzieren, indem sie die Mechanismen der Overlay-Netzwerke optimieren. Ein Ansatz zur Optimierung ist die Verwendung von Topologiebewusstsein innerhalb der Overlay-Netzwerke. Dabei erhalten die Nutzer der Overlay-Netzwerke Informationen über die zugrunde liegende, physikalische Netzwerktopologie. Diese ermöglichen es ihnen, Inter-ISP Verkehr zu vermeiden, indem sie Daten bevorzugt mit anderen Nutzern austauschen, die mit dem gleichen ISP verbunden sind. Ein weiterer Ansatz, um Inter-ISP Verkehr einzusparen, ist Caching. Dabei stellt der ISP zusätzliche Rechner, sogenannte Caches, in seinem Netzwerk zur Verfügung, die Kopien populärer Inhalte zwischenspeichern. Die Nutzer dieses ISP können solche Inhalte nun von den Caches beziehen. Dies verhindert, dass populäre Inhalte mehrfach von außerhalb des betrachteten ISPs bezogen werden müssen, und spart so kostenintensiven Inter-ISP Verkehr ein. Im dritten Kapitel der Arbeit werden Ergebnisse einer umfassenden Messung von Overlay-Netzwerken vorgestellt, wie sie heute im Internet anzutreffen sind. Nach einer kurzen Darstellung der bei der Messung verwendeten Methodik werden die Resultate der Messungen beschrieben. Diese Ergebnisse enthalten Daten über eine Vielzahl von Eigenschaften von heutigen P2P-basierten Overlay-Netzwerken im Internet. Dazu zählen die Popularität von Inhalten, d.h., wie viele Nutzer an bestimmten Inhalten interessiert sind, die zeitliche Entwicklung der Popularität und die Größe der Daten. Im Detail wird auch die Verteilung der Nutzer über das Internet analysiert. Ein besonderes Augenmerk liegt dabei auf der Anzahl der Nutzer, die gleichzeitig und im Netz desselben ISP eine bestimmte Datei tauschen. Auf der Basis dieser Messergebnisse wird eine Abschätzung durchgeführt, welches Einsparpotential die Optimierung von Overlay-Netzwerken durch Topologiebewusstsein bietet. Diese neuartige Abschätzung ist von wissenschaftlicher und praktischer Bedeutung, da sie sich nicht auf einzelne ISPs und Dateien beschränkt, sondern des gesamte Internet und die Menge aller in Overlay-Netzwerken verfügbaren Dateien umfasst. Schließlich werden die Besonderheiten von regionalen Inhalten betrachtet, bei denen sich die Popularität auf bestimmte Teile des Internets beschränkt. Dies ist beispielsweise bei Videos in deutscher, italienischer oder französischer Sprache der Fall. Kapitel 4 der Arbeit widmet sich der Optimierung von Overlay-Netzwerken zum Verteilen großer Datenmengen durch Caching. Es wird ein deterministisches Flussmodel entwickelt, das den Einfluss von Caches beschreibt. Auf der Basis dieses Modells leitet er eine Abschätzung des Inter-ISP Verkehrs ab, der von einem Overlay-Netzwerk erzeugt wird, und welcher Teil davon durch Caches eingespart werden kann. Die Ergebnisse zeigen, dass der Einfluss von Caches von der Struktur der Overlay-Netzwerke abhängt und dass Caches unter bestimmten Umständen auch zu einem erhöhten Inter-ISP Verkehr führen können. Das beschriebene Modell ist somit ein wichtiges Hilfsmittel für ISPs um zu entscheiden, für welche Overlay-Netzwerke Caches sinnvoll sind, und um diese anschließend richtig zu dimensionieren. Kapitel 5 fasst den Inhalt der Arbeit zusammen und stellt die Bedeutung der gewonnenen Erkenntnisse heraus. Abschließend wird erläutert, in welcher Weise die in der Arbeit beschriebenen Ergebnisse wichtige Grundlagen für die Optimierung von zukünftigen Overlay-Netzwerken darstellen werden. Dabei wird besonders auf die wachsende Bedeutung von Video-On-Demand und Echt-Zeit Video-Übertragungen eingegangen. T3 - Würzburger Beiträge zur Leistungsbewertung Verteilter Systeme - 01/13 KW - Leistungsbewertung KW - Verteiltes System KW - Overlay-Netz KW - Overlay Netzwerke KW - Overlay networks Y1 - 2013 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-76018 ER - TY - JOUR A1 - Lesch, Veronika A1 - König, Maximilian A1 - Kounev, Samuel A1 - Stein, Anthony A1 - Krupitzer, Christian T1 - Tackling the rich vehicle routing problem with nature-inspired algorithms JF - Applied Intelligence N2 - In the last decades, the classical Vehicle Routing Problem (VRP), i.e., assigning a set of orders to vehicles and planning their routes has been intensively researched. As only the assignment of order to vehicles and their routes is already an NP-complete problem, the application of these algorithms in practice often fails to take into account the constraints and restrictions that apply in real-world applications, the so called rich VRP (rVRP) and are limited to single aspects. In this work, we incorporate the main relevant real-world constraints and requirements. We propose a two-stage strategy and a Timeline algorithm for time windows and pause times, and apply a Genetic Algorithm (GA) and Ant Colony Optimization (ACO) individually to the problem to find optimal solutions. Our evaluation of eight different problem instances against four state-of-the-art algorithms shows that our approach handles all given constraints in a reasonable time. KW - logistics KW - rich vehicle routing problem KW - ant-colony optimization KW - genetic algorithm KW - real-world application Y1 - 2022 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-268942 SN - 1573-7497 VL - 52 ER - TY - RPRT A1 - Lhamo, Osel A1 - Nguyen, Giang T. A1 - Fitzek, Frank H. P. T1 - Virtual Queues for QoS Compliance of Haptic Data Streams in Teleoperation T2 - Würzburg Workshop on Next-Generation Communication Networks (WueWoWas'22) N2 - Tactile Internet aims at allowing perceived real-time interactions between humans and machines. This requires satisfying a stringent latency requirement of haptic data streams whose data rates vary drastically as the results of perceptual codecs. This introduces a complex problem for the underlying network infrastructure to fulfill the pre-defined level of Quality of Service (QoS). However, novel networking hardware with data plane programming capability allows processing packets differently and opens up a new opportunity. For example, a dynamic and network-aware resource management strategy can help satisfy the QoS requirements of different priority flows without wasting precious bandwidth. This paper introduces virtual queues for service differentiation between different types of traffic streams, leveraging protocol independent switch architecture (PISA). We propose coordinating the management of all the queues and dynamically adapting their sizes to minimize packet loss and delay due to network congestion and ensure QoS compliance. KW - Datennetz KW - data plane programming KW - software defined network KW - P4 KW - virtual queue KW - haptic data Y1 - 2022 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-280762 ER - TY - JOUR A1 - Li, Ningbo A1 - Guan, Lianwu A1 - Gao, Yanbin A1 - Du, Shitong A1 - Wu, Menghao A1 - Guang, Xingxing A1 - Cong, Xiaodan T1 - Indoor and outdoor low-cost seamless integrated navigation system based on the integration of INS/GNSS/LIDAR system JF - Remote Sensing N2 - Global Navigation Satellite System (GNSS) provides accurate positioning data for vehicular navigation in open outdoor environment. In an indoor environment, Light Detection and Ranging (LIDAR) Simultaneous Localization and Mapping (SLAM) establishes a two-dimensional map and provides positioning data. However, LIDAR can only provide relative positioning data and it cannot directly provide the latitude and longitude of the current position. As a consequence, GNSS/Inertial Navigation System (INS) integrated navigation could be employed in outdoors, while the indoors part makes use of INS/LIDAR integrated navigation and the corresponding switching navigation will make the indoor and outdoor positioning consistent. In addition, when the vehicle enters the garage, the GNSS signal will be blurred for a while and then disappeared. Ambiguous GNSS satellite signals will lead to the continuous distortion or overall drift of the positioning trajectory in the indoor condition. Therefore, an INS/LIDAR seamless integrated navigation algorithm and a switching algorithm based on vehicle navigation system are designed. According to the experimental data, the positioning accuracy of the INS/LIDAR navigation algorithm in the simulated environmental experiment is 50% higher than that of the Dead Reckoning (DR) algorithm. Besides, the switching algorithm developed based on the INS/LIDAR integrated navigation algorithm can achieve 80% success rate in navigation mode switching. KW - vehicular navigation KW - GNSS/INS integrated navigation KW - INS/LIDAR integrated navigation KW - switching navigation Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-216229 SN - 2072-4292 VL - 12 IS - 19 ER - TY - JOUR A1 - Liman, Leon A1 - May, Bernd A1 - Fette, Georg A1 - Krebs, Jonathan A1 - Puppe, Frank T1 - Using a clinical data warehouse to calculate and present key metrics for the radiology department: implementation and performance evaluation JF - JMIR Medical Informatics N2 - Background: Due to the importance of radiologic examinations, such as X-rays or computed tomography scans, for many clinical diagnoses, the optimal use of the radiology department is 1 of the primary goals of many hospitals. Objective: This study aims to calculate the key metrics of this use by creating a radiology data warehouse solution, where data from radiology information systems (RISs) can be imported and then queried using a query language as well as a graphical user interface (GUI). Methods: Using a simple configuration file, the developed system allowed for the processing of radiology data exported from any kind of RIS into a Microsoft Excel, comma-separated value (CSV), or JavaScript Object Notation (JSON) file. These data were then imported into a clinical data warehouse. Additional values based on the radiology data were calculated during this import process by implementing 1 of several provided interfaces. Afterward, the query language and GUI of the data warehouse were used to configure and calculate reports on these data. For the most common types of requested reports, a web interface was created to view their numbers as graphics. Results: The tool was successfully tested with the data of 4 different German hospitals from 2018 to 2021, with a total of 1,436,111 examinations. The user feedback was good, since all their queries could be answered if the available data were sufficient. The initial processing of the radiology data for using them with the clinical data warehouse took (depending on the amount of data provided by each hospital) between 7 minutes and 1 hour 11 minutes. Calculating 3 reports of different complexities on the data of each hospital was possible in 1-3 seconds for reports with up to 200 individual calculations and in up to 1.5 minutes for reports with up to 8200 individual calculations. Conclusions: A system was developed with the main advantage of being generic concerning the export of different RISs as well as concerning the configuration of queries for various reports. The queries could be configured easily using the GUI of the data warehouse, and their results could be exported into the standard formats Excel and CSV for further processing. KW - data warehouse KW - eHealth KW - hospital data KW - electronic health records KW - radiology KW - statistics and numerical data KW - medical records Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-349411 SN - 2291-9694 VL - 11 ER - TY - JOUR A1 - Linsenmann, Thomas A1 - März, Alexander A1 - Dufner, Vera A1 - Stetter, Christian A1 - Weiland, Judith A1 - Westermaier, Thomas T1 - Optimization of radiation settings for angiography using 3D fluoroscopy for imaging of intracranial aneurysms JF - Computer Assisted Surgery N2 - Mobile 3D fluoroscopes have become increasingly available in neurosurgical operating rooms. We recently reported its use for imaging cerebral vascular malformations and aneurysms. This study was conducted to evaluate various radiation settings for the imaging of cerebral aneurysms before and after surgical occlusion. Eighteen patients with cerebral aneurysms with the indication for surgical clipping were included in this prospective analysis. Before surgery the patients were randomized into one of three different scan protocols according (default settings of the 3D fluoroscope): Group 1: 110 kV, 80 mA (enhanced cranial mode), group 2: 120 kV, 64 mA (lumbar spine mode), group 3: 120 kV, 25 mA (head/neck settings). Prior to surgery, a rotational fluoroscopy scan (duration 24 s) was performed without contrast agent followed by another scan with 50 ml of intravenous iodine contrast agent. The image files of both scans were transferred to an Apple PowerMac(R) workstation, subtracted and reconstructed using OsiriX(R) MD 10.0 software. The procedure was repeated after clip placement. The image quality regarding preoperative aneurysm configuration and postoperative assessment of aneurysm occlusion and vessel patency was analyzed by 2 independent reviewers using a 6-grade scale. This technique quickly supplies images of adequate quality to depict intracranial aneurysms and distal vessel patency after aneurysm clipping. Regarding these features, a further optimization to our previous protocol seems possible lowering the voltage and increasing tube current. For quick intraoperative assessment, image subtraction seems not necessary. Thus, a native scan without a contrast agent is not necessary. Further optimization may be possible using a different contrast injection protocol. KW - 3D fluoroscopy KW - aneurysm KW - fluoroscopy KW - intraoperative imaging Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-259251 VL - 26 IS - 1 ER - TY - JOUR A1 - Loda, Sophia A1 - Krebs, Jonathan A1 - Danhof, Sophia A1 - Schreder, Martin A1 - Solimando, Antonio G. A1 - Strifler, Susanne A1 - Rasche, Leo A1 - Kortüm, Martin A1 - Kerscher, Alexander A1 - Knop, Stefan A1 - Puppe, Frank A1 - Einsele, Hermann A1 - Bittrich, Max T1 - Exploration of artificial intelligence use with ARIES in multiple myeloma research JF - Journal of Clinical Medicine N2 - Background: Natural language processing (NLP) is a powerful tool supporting the generation of Real-World Evidence (RWE). There is no NLP system that enables the extensive querying of parameters specific to multiple myeloma (MM) out of unstructured medical reports. We therefore created a MM-specific ontology to accelerate the information extraction (IE) out of unstructured text. Methods: Our MM ontology consists of extensive MM-specific and hierarchically structured attributes and values. We implemented “A Rule-based Information Extraction System” (ARIES) that uses this ontology. We evaluated ARIES on 200 randomly selected medical reports of patients diagnosed with MM. Results: Our system achieved a high F1-Score of 0.92 on the evaluation dataset with a precision of 0.87 and recall of 0.98. Conclusions: Our rule-based IE system enables the comprehensive querying of medical reports. The IE accelerates the extraction of data and enables clinicians to faster generate RWE on hematological issues. RWE helps clinicians to make decisions in an evidence-based manner. Our tool easily accelerates the integration of research evidence into everyday clinical practice. KW - natural language processing KW - ontology KW - artificial intelligence KW - multiple myeloma KW - real world evidence Y1 - 2019 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-197231 SN - 2077-0383 VL - 8 IS - 7 ER - TY - RPRT A1 - Loh, Frank A1 - Geißler, Stefan A1 - Hoßfeld, Tobias T1 - LoRaWAN Network Planning in Smart Environments: Towards Reliability, Scalability, and Cost Reduction T2 - Würzburg Workshop on Next-Generation Communication Networks (WueWoWas'22) N2 - The goal in this work is to present a guidance for LoRaWAN planning to improve overall reliability for message transmissions and scalability. At the end, the cost component is discussed. Therefore, a five step approach is presented that helps to plan a LoRaWAN deployment step by step: Based on the device locations, an initial gateway placement is suggested followed by in-depth frequency and channel access planning. After an initial planning phase, updates for channel access and the initial gateway planning is suggested that should also be done periodically during network operation. Since current gateway placement approaches are only studied with random channel access, there is a lot of potential in the cell planning phase. Furthermore, the performance of different channel access approaches is highly related on network load, and thus cell size and sensor density. Last, the influence of different cell planning ideas on expected costs are discussed. KW - Datennetz KW - LoRaWan Y1 - 2022 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-280829 ER - TY - JOUR A1 - Loh, Frank A1 - Mehling, Noah A1 - Hoßfeld, Tobias T1 - Towards LoRaWAN without data loss: studying the performance of different channel access approaches JF - Sensors N2 - The Long Range Wide Area Network (LoRaWAN) is one of the fastest growing Internet of Things (IoT) access protocols. It operates in the license free 868 MHz band and gives everyone the possibility to create their own small sensor networks. The drawback of this technology is often unscheduled or random channel access, which leads to message collisions and potential data loss. For that reason, recent literature studies alternative approaches for LoRaWAN channel access. In this work, state-of-the-art random channel access is compared with alternative approaches from the literature by means of collision probability. Furthermore, a time scheduled channel access methodology is presented to completely avoid collisions in LoRaWAN. For this approach, an exhaustive simulation study was conducted and the performance was evaluated with random access cross-traffic. In a general theoretical analysis the limits of the time scheduled approach are discussed to comply with duty cycle regulations in LoRaWAN. KW - LoRaWAN KW - IoT KW - channel management KW - scheduling KW - collision Y1 - 2022 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-302418 SN - 1424-8220 VL - 22 IS - 2 ER - TY - JOUR A1 - Loh, Frank A1 - Poignée, Fabian A1 - Wamser, Florian A1 - Leidinger, Ferdinand A1 - Hoßfeld, Tobias T1 - Uplink vs. Downlink: Machine Learning-Based Quality Prediction for HTTP Adaptive Video Streaming JF - Sensors N2 - Streaming video is responsible for the bulk of Internet traffic these days. For this reason, Internet providers and network operators try to make predictions and assessments about the streaming quality for an end user. Current monitoring solutions are based on a variety of different machine learning approaches. The challenge for providers and operators nowadays is that existing approaches require large amounts of data. In this work, the most relevant quality of experience metrics, i.e., the initial playback delay, the video streaming quality, video quality changes, and video rebuffering events, are examined using a voluminous data set of more than 13,000 YouTube video streaming runs that were collected with the native YouTube mobile app. Three Machine Learning models are developed and compared to estimate playback behavior based on uplink request information. The main focus has been on developing a lightweight approach using as few features and as little data as possible, while maintaining state-of-the-art performance. KW - HTTP adaptive video streaming KW - quality of experience prediction KW - machine learning Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-241121 SN - 1424-8220 VL - 21 IS - 12 ER - TY - RPRT A1 - Loh, Frank A1 - Raffeck, Simon A1 - Geißler, Stefan A1 - Hoßfeld, Tobias T1 - Paving the Way for an Energy Efficient and Sustainable Future Internet of Things T2 - KuVS Fachgespräch - Würzburg Workshop on Modeling, Analysis and Simulation of Next-Generation Communication Networks 2023 (WueWoWAS’23) N2 - In this work, we describe the network from data collection to data processing and storage as a system based on different layers. We outline the different layers and highlight major tasks and dependencies with regard to energy consumption and energy efficiency. With this view, we can outwork challenges and questions a future system architect must answer to provide a more sustainable, green, resource friendly, and energy efficient application or system. Therefore, all system layers must be considered individually but also altogether for future IoT solutions. This requires, in particular, novel sustainability metrics in addition to current Quality of Service and Quality of Experience metrics to provide a high power, user satisfying, and sustainable network. KW - Internet of Things KW - energy efficiency KW - sustainability Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-322161 ER - TY - JOUR A1 - Loh, Frank A1 - Wamser, Florian A1 - Poignée, Fabian A1 - Geißler, Stefan A1 - Hoßfeld, Tobias T1 - YouTube Dataset on Mobile Streaming for Internet Traffic Modeling and Streaming Analysis JF - Scientific Data N2 - Around 4.9 billion Internet users worldwide watch billions of hours of online video every day. As a result, streaming is by far the predominant type of traffic in communication networks. According to Google statistics, three out of five video views come from mobile devices. Thus, in view of the continuous technological advances in end devices and increasing mobile use, datasets for mobile streaming are indispensable in research but only sparsely dealt with in literature so far. With this public dataset, we provide 1,081 hours of time-synchronous video measurements at network, transport, and application layer with the native YouTube streaming client on mobile devices. The dataset includes 80 network scenarios with 171 different individual bandwidth settings measured in 5,181 runs with limited bandwidth, 1,939 runs with emulated 3 G/4 G traces, and 4,022 runs with pre-defined bandwidth changes. This corresponds to 332 GB video payload. We present the most relevant quality indicators for scientific use, i.e., initial playback delay, streaming video quality, adaptive video quality changes, video rebuffering events, and streaming phases. KW - internet traffic KW - mobile streaming KW - YouTube Y1 - 2022 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-300240 VL - 9 IS - 1 ER - TY - JOUR A1 - Lopez-Arreguin, A. J. R. A1 - Montenegro, S. T1 - Improving engineering models of terramechanics for planetary exploration JF - Results in Engineering N2 - This short letter proposes more consolidated explicit solutions for the forces and torques acting on typical rover wheels, that can be used as a method to determine their average mobility characteristics in planetary soils. The closed loop solutions stand in one of the verified methods, but at difference of the previous, observables are decoupled requiring a less amount of physical parameters to measure. As a result, we show that with knowledge of terrain properties, wheel driving performance rely in a single observable only. Because of their generality, the formulated equations established here can have further implications in autonomy and control of rovers or planetary soil characterization. KW - Wheel KW - Terramechanics KW - Forces KW - Torque KW - Robotics Y1 - 2019 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-202490 VL - 3 ER - TY - JOUR A1 - Lugrin, Jean-Luc A1 - Latoschik, Marc Erich A1 - Habel, Michael A1 - Roth, Daniel A1 - Seufert, Christian A1 - Grafe, Silke T1 - Breaking Bad Behaviors: A New Tool for Learning Classroom Management Using Virtual Reality JF - Frontiers in ICT N2 - This article presents an immersive virtual reality (VR) system for training classroom management skills, with a specific focus on learning to manage disruptive student behavior in face-to-face, one-to-many teaching scenarios. The core of the system is a real-time 3D virtual simulation of a classroom populated by twenty-four semi-autonomous virtual students. The system has been designed as a companion tool for classroom management seminars in a syllabus for primary and secondary school teachers. This will allow lecturers to link theory with practice using the medium of VR. The system is therefore designed for two users: a trainee teacher and an instructor supervising the training session. The teacher is immersed in a real-time 3D simulation of a classroom by means of a head-mounted display and headphone. The instructor operates a graphical desktop console, which renders a view of the class and the teacher whose avatar movements are captured by a marker less tracking system. This console includes a 2D graphics menu with convenient behavior and feedback control mechanisms to provide human-guided training sessions. The system is built using low-cost consumer hardware and software. Its architecture and technical design are described in detail. A first evaluation confirms its conformance to critical usability requirements (i.e., safety and comfort, believability, simplicity, acceptability, extensibility, affordability, and mobility). Our initial results are promising and constitute the necessary first step toward a possible investigation of the efficiency and effectiveness of such a system in terms of learning outcomes and experience. KW - virtual reality training KW - immersive classroom management KW - immersive classroom KW - virtual agent interaction KW - student simulation Y1 - 2016 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-147945 VL - 3 IS - 26 ER - TY - THES A1 - Löffler, Andre T1 - Constrained Graph Layouts: Vertices on the Outer Face and on the Integer Grid T1 - Graphzeichnen unter Nebenbedingungen: Knoten auf der Außenfacette und mit ganzzahligen Koordinaten N2 - Constraining graph layouts - that is, restricting the placement of vertices and the routing of edges to obey certain constraints - is common practice in graph drawing. In this book, we discuss algorithmic results on two different restriction types: placing vertices on the outer face and on the integer grid. For the first type, we look into the outer k-planar and outer k-quasi-planar graphs, as well as giving a linear-time algorithm to recognize full and closed outer k-planar graphs Monadic Second-order Logic. For the second type, we consider the problem of transferring a given planar drawing onto the integer grid while perserving the original drawings topology; we also generalize a variant of Cauchy's rigidity theorem for orthogonal polyhedra of genus 0 to those of arbitrary genus. N2 - Das Einschränken von Zeichnungen von Graphen, sodass diese bestimmte Nebenbedingungen erfüllen - etwa solche, die das Platzieren von Knoten oder den Verlauf von Kanten beeinflussen - sind im Graphzeichnen allgegenwärtig. In dieser Arbeit befassen wir uns mit algorithmischen Resultaten zu zwei speziellen Einschränkungen, nämlich dem Platzieren von Knoten entweder auf der Außenfacette oder auf ganzzahligen Koordinaten. Für die erste Einschränkung untersuchen wir die außen k-planaren und außen k-quasi-planaren Graphen und geben einen auf monadische Prädikatenlogik zweiter Stufe basierenden Algorithmus an, der überprüft, ob ein Graph voll außen k-planar ist. Für die zweite Einschränkung untersuchen wir das Problem, eine gegebene planare Zeichnung eines Graphen auf das ganzzahlige Koordinatengitter zu transportieren, ohne dabei die Topologie der Zeichnung zu verändern; außerdem generalisieren wir eine Variante von Cauchys Starrheitssatz für orthogonale Polyeder von Geschlecht 0 auf solche von beliebigem Geschlecht. KW - Graphenzeichnen KW - Komplexität KW - Algorithmus KW - Algorithmische Geometrie KW - Kombinatorik KW - Planare Graphen KW - Polyeder KW - Konvexe Zeichnungen Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-215746 SN - 978-3-95826-146-4 SN - 978-3-95826-147-1 N1 - Parallel erschienen als Druckausgabe in Würzburg University Press, ISBN 978-3-95826-146-4, 32,90 EUR PB - Würzburg University Press CY - Würzburg ET - 1. Auflage ER - TY - JOUR A1 - Madeira, Octavia A1 - Gromer, Daniel A1 - Latoschik, Marc Erich A1 - Pauli, Paul T1 - Effects of Acrophobic Fear and Trait Anxiety on Human Behavior in a Virtual Elevated Plus-Maze JF - Frontiers in Virtual Reality N2 - The Elevated Plus-Maze (EPM) is a well-established apparatus to measure anxiety in rodents, i.e., animals exhibiting an increased relative time spent in the closed vs. the open arms are considered anxious. To examine whether such anxiety-modulated behaviors are conserved in humans, we re-translated this paradigm to a human setting using virtual reality in a Cave Automatic Virtual Environment (CAVE) system. In two studies, we examined whether the EPM exploration behavior of humans is modulated by their trait anxiety and also assessed the individuals’ levels of acrophobia (fear of height), claustrophobia (fear of confined spaces), sensation seeking, and the reported anxiety when on the maze. First, we constructed an exact virtual copy of the animal EPM adjusted to human proportions. In analogy to animal EPM studies, participants (N = 30) freely explored the EPM for 5 min. In the second study (N = 61), we redesigned the EPM to make it more human-adapted and to differentiate influences of trait anxiety and acrophobia by introducing various floor textures and lower walls of closed arms to the height of standard handrails. In the first experiment, hierarchical regression analyses of exploration behavior revealed the expected association between open arm avoidance and Trait Anxiety, an even stronger association with acrophobic fear. In the second study, results revealed that acrophobia was associated with avoidance of open arms with mesh-floor texture, whereas for trait anxiety, claustrophobia, and sensation seeking, no effect was detected. Also, subjects’ fear rating was moderated by all psychometrics but trait anxiety. In sum, both studies consistently indicate that humans show no general open arm avoidance analogous to rodents and that human EPM behavior is modulated strongest by acrophobic fear, whereas trait anxiety plays a subordinate role. Thus, we conclude that the criteria for cross-species validity are met insufficiently in this case. Despite the exploratory nature, our studies provide in-depth insights into human exploration behavior on the virtual EPM. KW - elevated plus-maze KW - EPM KW - anxiety KW - virtual reality KW - translational neuroscience KW - acrophobia KW - trait anxiety Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-258709 VL - 2 ER - TY - JOUR A1 - Maiwald, Ferdinand A1 - Bruschke, Jonas A1 - Schneider, Danilo A1 - Wacker, Markus A1 - Niebling, Florian T1 - Giving historical photographs a new perspective: introducing camera orientation parameters as new metadata in a large-scale 4D application JF - Remote Sensing N2 - The ongoing digitization of historical photographs in archives allows investigating the quality, quantity, and distribution of these images. However, the exact interior and exterior camera orientations of these photographs are usually lost during the digitization process. The proposed method uses content-based image retrieval (CBIR) to filter exterior images of single buildings in combination with metadata information. The retrieved photographs are automatically processed in an adapted structure-from-motion (SfM) pipeline to determine the camera parameters. In an interactive georeferencing process, the calculated camera positions are transferred into a global coordinate system. As all image and camera data are efficiently stored in the proposed 4D database, they can be conveniently accessed afterward to georeference newly digitized images by using photogrammetric triangulation and spatial resection. The results show that the CBIR and the subsequent SfM are robust methods for various kinds of buildings and different quantity of data. The absolute accuracy of the camera positions after georeferencing lies in the range of a few meters likely introduced by the inaccurate LOD2 models used for transformation. The proposed photogrammetric method, the database structure, and the 4D visualization interface enable adding historical urban photographs and 3D models from other locations. KW - historical images KW - 4D-GIS KW - content-based image retrieval KW - Structure-from-Motion KW - camera orientation KW - feature matching Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-311103 SN - 2072-4292 VL - 15 IS - 7 ER - TY - THES A1 - Martin, Rüdiger T1 - Resilience, Provisioning, and Control for the Network of the Future T1 - Ausfallsicherheit, Dimensionierungsansätze und Kontrollmechanismen für das Netz der Zukunft N2 - The Internet sees an ongoing transformation process from a single best-effort service network into a multi-service network. In addition to traditional applications like e-mail,WWW-traffic, or file transfer, future generation networks (FGNs) will carry services with real-time constraints and stringent availability and reliability requirements like Voice over IP (VoIP), video conferencing, virtual private networks (VPNs) for finance, other real-time business applications, tele-medicine, or tele-robotics. Hence, quality of service (QoS) guarantees and resilience to failures are crucial characteristics of an FGN architecture. At the same time, network operations must be efficient. This necessitates sophisticated mechanisms for the provisioning and the control of future communication infrastructures. In this work we investigate such echanisms for resilient FGNs. There are many aspects of the provisioning and control of resilient FGNs such as traffic matrix estimation, traffic characterization, traffic forecasting, mechanisms for QoS enforcement also during failure cases, resilient routing, or calability concerns for future routing and addressing mechanisms. In this work we focus on three important aspects for which performance analysis can deliver substantial insights: load balancing for multipath Internet routing, fast resilience concepts, and advanced dimensioning techniques for resilient networks. Routing in modern communication networks is often based on multipath structures, e.g., equal-cost multipath routing (ECMP) in IP networks, to facilitate traffic engineering and resiliency. When multipath routing is applied, load balancing algorithms distribute the traffic over available paths towards the destination according to pre-configured distribution values. State-of-the-art load balancing algorithms operate either on the packet or the flow level. Packet level mechanisms achieve highly accurate traffic distributions, but are known to have negative effects on the performance of transport protocols and should not be applied. Flow level mechanisms avoid performance degradations, but at the expense of reduced accuracy. These inaccuracies may have unpredictable effects on link capacity requirements and complicate resource management. Thus, it is important to exactly understand the accuracy and dynamics of load balancing algorithms in order to be able to exercise better network control. Knowing about their weaknesses, it is also important to look for alternatives and to assess their applicability in different networking scenarios. This is the first aspect of this work. Component failures are inevitable during the operation of communication networks and lead to routing disruptions if no special precautions are taken. In case of a failure, the robust shortest-path routing of the Internet reconverges after some time to a state where all nodes are again reachable – provided physical connectivity still exists. But stringent availability and reliability criteria of new services make a fast reaction to failures obligatory for resilient FGNs. This led to the development of fast reroute (FRR) concepts for MPLS and IP routing. The operations of MPLS-FRR have already been standardized. Still, the standards leave some degrees of freedom for the resilient path layout and it is important to understand the tradeoffs between different options for the path layout to efficiently provision resilient FGNs. In contrast, the standardization for IP-FRR is an ongoing process. The applicability and possible combinations of different concepts still are open issues. IP-FRR also facilitates a comprehensive resilience framework for IP routing covering all steps of the failure recovery cycle. These points constitute another aspect of this work. Finally, communication networks are usually over-provisioned, i.e., they have much more capacity installed than actually required during normal operation. This is a precaution for various challenges such as network element failures. An alternative to this capacity overprovisioning (CO) approach is admission control (AC). AC blocks new flows in case of imminent overload due to unanticipated events to protect the QoS for already admitted flows. On the one hand, CO is generally viewed as a simple mechanism, AC as a more complex mechanism that complicates the network control plane and raises interoperability issues. On the other hand, AC appears more cost-efficient than CO. To obtain advanced provisioning methods for resilient FGNs, it is important to find suitable models for irregular events, such as failures and different sources of overload, and to incorporate them into capacity dimensioning methods. This allows for a fair comparison between CO and AC in various situations and yields a better understanding of the strengths and weaknesses of both concepts. Such an advanced capacity dimensioning method for resilient FGNs represents the third aspect of this work. N2 - Das Internet befindet sich gegenwärtig in einem Transformationsprozess von einem Netz mit einer einzigen best-effort Dienstklasse hin zu einem Mehr-Dienste-Netz. Zusätzlich zu herkömmlichen Anwendungen wie E-Mail, WWW oder Datenübertragung werden zukünftige Netze Dienste mit Echtzeitbedürfnissen und strikten Anforderungen an Verfügbarkeit und Zuverlässigkeit wie Voice over IP (VoIP), Videokonferenzdienste, Virtual Private Networks (VPNs) für Finanzanwendungen und andere Geschäftsanwendungen mit Echtzeitanforderungen, Tele-Medizin oder Telerobotik tragen. Daher sind die Gewährleistung von Dienstgüte und Ausfallsicherheit wesentliche Merkmale zukünftiger Netzarchitekturen. Gleichzeitig muss der Netzbetrieb effizient sein. Dies zieht den Bedarf an ausgefeilten Mechanismen für die Dimensionierung und Kontrolle ausfallsicherer Kommunikationsstrukturen nach sich. In dieser Arbeit werden solche Mechanismen, nämlich Lastaufteilung, Konzepte zur schnellen Reaktion im Fehlerfall und intelligente Ansätze zur Netzdimensionierung, untersucht. T3 - Würzburger Beiträge zur Leistungsbewertung Verteilter Systeme - 03/08 KW - Backbone-Netz KW - load balancing KW - resilience KW - fast reroute KW - admission control KW - overprovisioning Y1 - 2008 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-28497 ER - TY - RPRT A1 - Martino, Luigi A1 - Deutschmann, Jörg A1 - Hielscher, Kai-Steffen A1 - German, Reinhard T1 - Towards a 5G Satellite Communication Framework for V2X T2 - KuVS Fachgespräch - Würzburg Workshop on Modeling, Analysis and Simulation of Next-Generation Communication Networks 2023 (WueWoWAS’23) N2 - In recent years, satellite communication has been expanding its field of application in the world of computer networks. This paper aims to provide an overview of how a typical scenario involving 5G Non-Terrestrial Networks (NTNs) for vehicle to everything (V2X) applications is characterized. In particular, a first implementation of a system that integrates them together will be described. Such a framework will later be used to evaluate the performance of applications such as Vehicle Monitoring (VM), Remote Driving (RD), Voice Over IP (VoIP), and others. Different configuration scenarios such as Low Earth Orbit and Geostationary Orbit will be considered. KW - 5G KW - non-terrestrial networks KW - satellite communication Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-322148 ER - TY - RPRT A1 - Mazigh, Sadok Mehdi A1 - Beausencourt, Marcel A1 - Bode, Max Julius A1 - Scheffler, Thomas T1 - Using P4-INT on Tofino for Measuring Device Performance Characteristics in a Network Lab T2 - KuVS Fachgespräch - Würzburg Workshop on Modeling, Analysis and Simulation of Next-Generation Communication Networks 2023 (WueWoWAS’23) N2 - This paper presents a prototypical implementation of the In-band Network Telemetry (INT) specification in P4 and demonstrates a use case, where a Tofino Switch is used to measure device and network performance in a lab setting. This work is based on research activities in the area of P4 data plane programming conducted at the network lab of HTW Berlin. KW - P4-INT Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-322084 ER - TY - THES A1 - Menth, Michael T1 - Efficient admission control and routing for resilient communication networks T1 - Effiziente Zugangskontrolle und Verkehrslenkung für ausfallsichere Kommunikationsnetze N2 - This work is subdivided into two main areas: resilient admission control and resilient routing. The work gives an overview of the state of the art of quality of service mechanisms in communication networks and proposes a categorization of admission control (AC) methods. These approaches are investigated regarding performance, more precisely, regarding the potential resource utilization by dimensioning the capacity for a network with a given topology, traffic matrix, and a required flow blocking probability. In case of a failure, the affected traffic is rerouted over backup paths which increases the traffic rate on the respective links. To guarantee the effectiveness of admission control also in failure scenarios, the increased traffic rate must be taken into account for capacity dimensioning and leads to resilient AC. Capacity dimensioning is not feasible for existing networks with already given link capacities. For the application of resilient NAC in this case, the size of distributed AC budgets must be adapted according to the traffic matrix in such a way that the maximum blocking probability for all flows is minimized and that the capacity of all links is not exceeded by the admissible traffic rate in any failure scenario. Several algorithms for the solution of that problem are presented and compared regarding their efficiency and fairness. A prototype for resilient AC was implemented in the laboratories of Siemens AG in Munich within the scope of the project KING. Resilience requires additional capacity on the backup paths for failure scenarios. The amount of this backup capacity depends on the routing and can be minimized by routing optimization. New protection switching mechanisms are presented that deviate the traffic quickly around outage locations. They are simple and can be implemented, e.g, by MPLS technology. The Self-Protecting Multi-Path (SPM) is a multi-path consisting of disjoint partial paths. The traffic is distributed over all faultless partial paths according to an optimized load balancing function both in the working case and in failure scenarios. Performance studies show that the network topology and the traffic matrix also influence the amount of required backup capacity significantly. The example of the COST-239 network illustrates that conventional shortest path routing may need 50% more capacity than the optimized SPM if all single link and node failures are protected. N2 - Diese Arbeit gliedert sich in zwei Hauptteile: Ausfallsichere Zugangskontrolle und ausfallsichere Verkehrslenkung. Die Arbeit beschreibt zu Beginn den Stand der Technik für Dienstgütemechanismen in Kommunikationsnetzen und nimmt eine Kategorisierung von Zugangskontrollmethoden vor. Diese Ansätze werden hinsichtlich ihrer potentiellen Auslastung der Leitungskapaztitäten untersucht, indem die Kapazität für ein Netz mit gegebnener Topology, Verkehrsmatrix und geforderten Flussblockierwahrscheinlichkeiten dimensioniert wird. Im Falle eines Fehlers werden betroffene Flüsse automatisch über Ersatzpfade umgeleitet, was die Verkehrslast auf deren Übertragungsleitungen erhöht. Um die Wirksamkeit der Zugangskontrolle auch in Fehlerfällen zu gewährleisten, muss diese erhöhte Verkehrslast bei der Dimensionierung berücksichtigt werden, was zu einer ausfallsicheren Zugangskontrolle führt. Kapazitätsdimensionierung ist in bereits existierenden Netzen mit festen Linkbandbreiten nicht mehr möglich. Für die Anwendung von ausfallsicherer Zugangskontrolle in diesem Fall muss die Größe von verteilten Zugangskontrollbudgets gemäß der Verkehrsmatrix so angepasst werden, dass die maximale Blockierwahrscheinlichkeit aller Flüsse minimiert wird und die Kapazität aller Links in keinem Fehlerfall durch die zulässige Verkehrrate überschritten wird. Es werden unterschiedliche Algorithmen für die Lösung dieses Problems vorgeschlagen und hinsichtlich ihrer Effizienz und Fairness verglichen. Ein Prototyp für ausfallsichere Zugangskontrolle wurde im Rahmen des KING-Projektes in den Labors der Siemens AG in München implementiert. Ausfallsicherheit benötigt Zusatzkapazitäten auf den Ersatzpfaden für Fehlerfälle. Die Menge der Zusatzkapazität hängt von der Verkehrslenkung ab und kann durch Optimierung verringert werden. Es werden neue Mechanismen für Ersatzschaltungen vorgestellt, die den Verkehr schnell um Fehlerstellen im Netz herumleiten können. Sie zeichnen sich durch ihre Einfachheit aus und können z.B. in MPLS-Technologie implementiert werden. Der "Self-Protecting Multi-Path" (SPM) ist ein Multipfad, der aus disjunkten Teilpfaden besteht. Der Verkehr wird sowohl im Normalbetrieb als auch in Ausfallszenarien über alle intakten Teilpfade gemäß einer optimierten Lastverteilungsfunktion weitergeleitet. Leistungsuntersuchungen zeigen, dass die Menge an benötigter Zusatzkapazität deutlich von der Netztopologie und der Verkehrsmatrix abhängt. Das Beispiel des COST-239 Netzes veranschaulicht, dass herkömmliche Verkehrslenkung auf den kürzesten Wegen 50% mehr Kapazität benötigen kann als der optimierte SPM, wenn alle einzelnen Übertragungsleitungs- und Vermittlungsknotenausfälle geschützt werden. T3 - Würzburger Beiträge zur Leistungsbewertung Verteilter Systeme - 03/04 KW - Kommunikation KW - Netzwerk KW - Ausfallsicheres System KW - Kommunikationsnetze KW - Ausfallsicherheit KW - Zugangskontrolle KW - Verkehrslenkung KW - Communication Networks KW - Resilience KW - Admission Control KW - Routing Y1 - 2004 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-9949 ER - TY - JOUR A1 - Merget, Benjamin A1 - Koetschan, Christian A1 - Hackl, Thomas A1 - Förster, Frank A1 - Dandekar, Thomas A1 - Müller, Tobias A1 - Schultz, Jörg A1 - Wolf, Matthias T1 - The ITS2 Database JF - Journal of Visual Expression N2 - The internal transcribed spacer 2 (ITS2) has been used as a phylogenetic marker for more than two decades. As ITS2 research mainly focused on the very variable ITS2 sequence, it confined this marker to low-level phylogenetics only. However, the combination of the ITS2 sequence and its highly conserved secondary structure improves the phylogenetic resolution1 and allows phylogenetic inference at multiple taxonomic ranks, including species delimitation. The ITS2 Database presents an exhaustive dataset of internal transcribed spacer 2 sequences from NCBI GenBank accurately reannotated. Following an annotation by profile Hidden Markov Models (HMMs), the secondary structure of each sequence is predicted. First, it is tested whether a minimum energy based fold (direct fold) results in a correct, four helix conformation. If this is not the case, the structure is predicted by homology modeling. In homology modeling, an already known secondary structure is transferred to another ITS2 sequence, whose secondary structure was not able to fold correctly in a direct fold. The ITS2 Database is not only a database for storage and retrieval of ITS2 sequence-structures. It also provides several tools to process your own ITS2 sequences, including annotation, structural prediction, motif detection and BLAST search on the combined sequence-structure information. Moreover, it integrates trimmed versions of 4SALE and ProfDistS for multiple sequence-structure alignment calculation and Neighbor Joining tree reconstruction. Together they form a coherent analysis pipeline from an initial set of sequences to a phylogeny based on sequence and secondary structure. In a nutshell, this workbench simplifies first phylogenetic analyses to only a few mouse-clicks, while additionally providing tools and data for comprehensive large-scale analyses. KW - homology modeling KW - molecular systematics KW - internal transcribed spacer 2 KW - alignment KW - genetics KW - secondary structure KW - ribosomal RNA KW - phylogenetic tree KW - phylogeny Y1 - 2012 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-124600 VL - 61 IS - e3806 ER - TY - RPRT A1 - Metzger, Florian T1 - Crowdsensed QoE for the community - a concept to make QoE assessment accessible N2 - In recent years several community testbeds as well as participatory sensing platforms have successfully established themselves to provide open data to everyone interested. Each of them with a specific goal in mind, ranging from collecting radio coverage data up to environmental and radiation data. Such data can be used by the community in their decision making, whether to subscribe to a specific mobile phone service that provides good coverage in an area or in finding a sunny and warm region for the summer holidays. However, the existing platforms are usually limiting themselves to directly measurable network QoS. If such a crowdsourced data set provides more in-depth derived measures, this would enable an even better decision making. A community-driven crowdsensing platform that derives spatial application-layer user experience from resource-friendly bandwidth estimates would be such a case, video streaming services come to mind as a prime example. In this paper we present a concept for such a system based on an initial prototype that eases the collection of data necessary to determine mobile-specific QoE at large scale. In addition we reason why the simple quality metric proposed here can hold its own. KW - Quality of Experience KW - Crowdsourcing KW - Crowdsensing KW - QoE Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-203748 N1 - Originally written in 2017, but never published. ER - TY - THES A1 - Milbrandt, Jens T1 - Performance Evaluation of Efficient Resource Management Concepts for Next Generation IP Networks T1 - Effiziente Konzepte und Leistungsbewertung zum Ressourcen Management in zukünftigen IP Netzen N2 - Next generation networks (NGNs) must integrate the services of current circuit-switched telephone networks and packet-switched data networks. This convergence towards a unified communication infrastructure necessitates from the high capital expenditures (CAPEX) and operational expenditures (OPEX) due to the coexistence of separate networks for voice and data. In the end, NGNs must offer the same services as these legacy networks and, therefore, they must provide a low-cost packet-switched solution with real-time transport capabilities for telephony and multimedia applications. In addition, NGNs must be fault-tolerant to guarantee user satisfaction and to support business-critical processes also in case of network failures. A key technology for the operation of NGNs is the Internet Protocol (IP) which evolved to a common and well accepted standard for networking in the Internet during the last 25 years. There are two basically different approaches to achieve QoS in IP networks. With capacity overprovisioning (CO), an IP network is equipped with sufficient bandwidth such that network congestion becomes very unlikely and QoS is maintained most of the time. The second option to achieve QoS in IP networks is admission control (AC). AC represents a network-inherent intelligence that admits real-time traffic flows to a single link or an entire network only if enough resources are available such that the requirements on packet loss and delay can be met. Otherwise, the request of a new flow is blocked. This work focuses on resource management and control mechanisms for NGNs, in particular on AC and associated bandwidth allocation methods. The first contribution consists of a new link-oriented AC method called experience-based admission control (EBAC) which is a hybrid approach dealing with the problems inherent to conventional AC mechanisms like parameter-based or measurement-based AC (PBAC/MBAC). PBAC provides good QoS but suffers from poor resource utilization and, vice versa, MBAC uses resources efficiently but is susceptible to QoS violations. Hence, EBAC aims at increasing the resource efficiency while maintaining the QoS which increases the revenues of ISPs and postpones their CAPEX for infrastructure upgrades. To show the advantages of EBAC, we first review today’s AC approaches and then develop the concept of EBAC. EBAC is a simple mechanism that safely overbooks the capacity of a single link to increase its resource utilization. We evaluate the performance of EBAC by its simulation under various traffic conditions. The second contribution concerns dynamic resource allocation in transport networks which implement a specific network admission control (NAC) architecture. In general, the performance of different NAC systems may be evaluated by conventional methods such as call blocking analysis which has often been applied in the context of multi-service asynchronous transfer mode (ATM) networks. However, to yield more practical results than abstract blocking probabilities, we propose a new method to compare different AC approaches by their respective bandwidth requirements. To present our new method for comparing different AC systems, we first give an overview of network resource management (NRM) in general. Then we present the concept of adaptive bandwidth allocation (ABA) in capacity tunnels and illustrate the analytical performance evaluation framework to compare different AC systems by their capacity requirements. Different network characteristics influence the performance of ABA. Therefore, the impact of various traffic demand models and tunnel implementations, and the influence of resilience requirements is investigated. In conclusion, the resources in NGNs must be exclusively dedicated to admitted traffic to guarantee QoS. For that purpose, robust and efficient concepts for NRM are required to control the requested bandwidth with regard to the available transmission capacity. Sophisticated AC will be a key function for NRM in NGNs and, therefore, efficient resource management concepts like experience-based admission control and adaptive bandwidth allocation for admission-controlled capacity tunnels, as presented in this work are appealing for NGN solutions. N2 - In meiner Dissertation zum Thema “Performance Evaluation of Efficient Resource Management Concepts for Next Generation IP Networks” werden im Wesentlichen zwei miteinander verwobene Konzepte zur effizienten Nutzung von Übertragungsressourcen in zukünftigen IP Netzen untersucht. Das Management solcher Ressourcen ist zur Unterstützung qualitativ hochwertiger Netzdiensten (z.B. IP Telephonie, IP TV, etc.) in Zukunft unabdingbar. Gegenwärtig werden diese Dienste durch den Einsatz hoher Übertragungskapazitäten (engl. capacity overprovisioning) in den IP Breitbandnetzen ermöglicht. Um in Spitzenlastzeiten die Qualität der Dienste aufrecht zu erhalten, sind die Bandbreiten derart hoch angesetzt, dass unter normalen Umständen die Ressourcen nur sehr schwach ausgelastet sind (im Bereich zwischen 10 und 30 Prozent). Diese Überdimensionierungslösung ist einfach zu realisieren aber auch sehr kostenintensiv, ineffizient und vor allem nicht (zukunfts-)sicher, da bei ständig steigendem Bandbreitenbedarf, die Netzkapazitäten häufig angepasst werden müssen. Eine Effizienzsteigerung bei der Ressourcennutzung in heutigen Kommunikationsnetzen ist daher ein wichtiges Kriterium für die Wirtschaftlichkeit zukünftiger IP Netze. Erreicht werden kann dies mit den Mitteln der Netzzugangskontrolle (engl. admission control, kurz AC), welche bereits in verschiedenen Formen entwickelt, untersucht und teilweise auch in heutigen IP Netzen realisiert ist. Die AC stellt eine vergleichsweise komplexe Lösung zur Aufrechterhaltung der Dienstgüte in IP Netzen dar. Daher sind einfache und effiziente Mechanismen/Automatismen zur Durchführung der AC gefordert, um deren Einsatz an Stelle der Überdimensionierung zu rechtfertigen. Den zuvor genannten Forderungen nach effizienter Ressourcennutzung entsprechend stellt der erste Hauptbeitrag der Dissertation einen neuen Ansatz zur AC dar, die so genannte erfahrungsbasierte Netzzugangskontrolle (engl. experience-based admission control, kurz EBAC). Gegenüber den existierenden alternativen, d.h. parameter- oder mess-basierten Verfahren der AC zeichnet sich die EBAC durch effiziente Ressourcennutzung und begünstigt gleichzeitig die Aufrechterhaltung der Dienstgüte. Die genaue Funktionsweise der EBAC und die simulative Leistungsuntersuchung sind in der Dissertation nachzulesen. Der zweite Themenschwerpunkt der Dissertation greift eine tunnel-basierte Netzarchitektur auf und präsentiert mit deren Hilfe eine neue Methode zur Bewertung verschiedener Bandbreitenallokationsstrategien in Kombination mit AC. Die neue Bewertungsmethode wird zwar anhand einer speziellen tunnel-basierten AC untersucht, lässt sich aber auf alle Arten so genannter budget-basierter AC anwenden. Bei der konventionellen Leistungsbewertung verschiedener AC-Systeme dienen abstrakte Blockierungswahrscheinlichkeiten als Leistungsmaß. Im Gegensatz hierzu, bewertet die neue Methode die Leistung eines AC-Systems anhand des zugehörigen Bandbreitenbedarfs in Abhängigkeit verschiedener Einflussfaktoren, z.B. der avisierten Blockierwahrscheinlichkeit des AC-Systems, der Verkehrszusammensetzung, des Verkehrsvolumens, der Verkehrsdynamik und vor allem der angewandten Bandbreitenallokationsstrategie. In zukünftigen IP Netzen müssen die Ressourcen zur Datenübertragung besser verwaltet und kontrolliert werden. Zugelassener Verkehr mit hohen Dienstgüteanforderungen muss exklusiv Bandbreite zugewiesen werden, um die geforderte Dienstgüte garantieren zu können. Um dieses Ziel zu erreichen werden robuste und effiziente Konzepte zum Management von Netzressourcen benötigt. Intelligenter Netzzugangskontrolle wird eine Schlüsselfunktion in zukünftigen IP Netzen zukommen. Die in dieser Dissertation vorgestellten, effizienten Ressourcenmanagementkonzepte „erfahrungsbasierte Netzzugangskontrolle“ und „adaptive Bandbreitenallokation in zugangskontrollierten Kapazitätstunnel“ tragen zum Erreichen dieses Ziels bei. T3 - Würzburger Beiträge zur Leistungsbewertung Verteilter Systeme - 01/07 KW - Ressourcenmanagement KW - Leistungsbewertung KW - Rechnernetz KW - IP KW - Ressourcen Management KW - Leistungsbewertung KW - zukünftige Kommunikationsnetze KW - Resource Management KW - Performance Analysis KW - Next Generation Networks Y1 - 2007 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-23332 ER - TY - THES A1 - Mäder, Andreas T1 - Performance Models for UMTS 3.5G Mobile Wireless Systems T1 - Leistungsmodelle für UMTS 3.5G Mobilfunksysteme N2 - Mobile telecommunication systems of the 3.5th generation (3.5G) constitute a first step towards the requirements of an all-IP world. As the denotation suggests, 3.5G systems are not completely new designed from scratch. Instead, they are evolved from existing 3G systems like UMTS or cdma2000. 3.5G systems are primarily designed and optimized for packet-switched best-effort traffic, but they are also intended to increase system capacity by exploiting available radio resources more efficiently. Systems based on cdma2000 are enhanced with 1xEV-DO (EV-DO: evolution, data-optimized). In the UMTS domain, the 3G partnership project (3GPP) specified the High Speed Packet Access (HSPA) family, consisting of High Speed Downlink Packet Access (HSDPA) and its counterpart High Speed Uplink Packet Access (HSUPA) or Enhanced Uplink. The focus of this monograph is on HSPA systems, although the operation principles of other 3.5G systems are similar. One of the main contributions of our work are performance models which allow a holistic view on the system. The models consider user traffic on flow-level, such that only on significant changes of the system state a recalculation of parameters like bandwidth is necessary. The impact of lower layers is captured by stochastic models. This approach combines accurate modeling and the ability to cope with computational complexity. Adopting this approach to HSDPA, we develop a new physical layer abstraction model that takes radio resources, scheduling discipline, radio propagation and mobile device capabilities into account. Together with models for the calculation of network-wide interference and transmit powers, a discrete-event simulation and an analytical model based on a queuing-theoretical approach are proposed. For the Enhanced Uplink, we develop analytical models considering independent and correlated other-cell interference. N2 - Die vorliegende Arbeit beschäftigt sich mit Mobilfunksystemen der Generation 3.5 im Allgemeinen, und mit den UMTS-spezifischen Ausprägungen HSDPA (High Speed Downlink Packet Access) und HSUPA (High Speed Uplink Packet Access) bzw. Enhanced Uplink im speziellen. Es werden integrierte Systeme betrachtet, d.h. 3.5G Datenkanäle koexistieren mit "klassischen" UMTS Datenkanälen wie in den Spezifikationen von UMTS Release ´99 beschrieben. T3 - Würzburger Beiträge zur Leistungsbewertung Verteilter Systeme - 02/08 KW - Mobilfunk KW - Leistungsbewertung KW - UMTS KW - HSPA KW - Funkressourcenverwaltung KW - Modellierungstechniken KW - Netzwerkplanung KW - UMTS KW - HSPA KW - radio resource management KW - modeling techniques KW - network planning Y1 - 2008 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-32525 ER - TY - JOUR A1 - Müller, Konstantin A1 - Leppich, Robert A1 - Geiß, Christian A1 - Borst, Vanessa A1 - Pelizari, Patrick Aravena A1 - Kounev, Samuel A1 - Taubenböck, Hannes T1 - Deep neural network regression for normalized digital surface model generation with Sentinel-2 imagery JF - IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing N2 - In recent history, normalized digital surface models (nDSMs) have been constantly gaining importance as a means to solve large-scale geographic problems. High-resolution surface models are precious, as they can provide detailed information for a specific area. However, measurements with a high resolution are time consuming and costly. Only a few approaches exist to create high-resolution nDSMs for extensive areas. This article explores approaches to extract high-resolution nDSMs from low-resolution Sentinel-2 data, allowing us to derive large-scale models. We thereby utilize the advantages of Sentinel 2 being open access, having global coverage, and providing steady updates through a high repetition rate. Several deep learning models are trained to overcome the gap in producing high-resolution surface maps from low-resolution input data. With U-Net as a base architecture, we extend the capabilities of our model by integrating tailored multiscale encoders with differently sized kernels in the convolution as well as conformed self-attention inside the skip connection gates. Using pixelwise regression, our U-Net base models can achieve a mean height error of approximately 2 m. Moreover, through our enhancements to the model architecture, we reduce the model error by more than 7%. KW - Deep learning KW - multiscale encoder KW - sentinel KW - surface model Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-349424 SN - 1939-1404 VL - 16 ER - TY - JOUR A1 - Nagler, Matthias A1 - Nägele, Thomas A1 - Gilli, Christian A1 - Fragner, Lena A1 - Korte, Arthur A1 - Platzer, Alexander A1 - Farlow, Ashley A1 - Nordborg, Magnus A1 - Weckwerth, Wolfram T1 - Eco-Metabolomics and Metabolic Modeling: Making the Leap From Model Systems in the Lab to Native Populations in the Field JF - Frontiers in Plant Science N2 - Experimental high-throughput analysis of molecular networks is a central approach to characterize the adaptation of plant metabolism to the environment. However, recent studies have demonstrated that it is hardly possible to predict in situ metabolic phenotypes from experiments under controlled conditions, such as growth chambers or greenhouses. This is particularly due to the high molecular variance of in situ samples induced by environmental fluctuations. An approach of functional metabolome interpretation of field samples would be desirable in order to be able to identify and trace back the impact of environmental changes on plant metabolism. To test the applicability of metabolomics studies for a characterization of plant populations in the field, we have identified and analyzed in situ samples of nearby grown natural populations of Arabidopsis thaliana in Austria. A. thaliana is the primary molecular biological model system in plant biology with one of the best functionally annotated genomes representing a reference system for all other plant genome projects. The genomes of these novel natural populations were sequenced and phylogenetically compared to a comprehensive genome database of A. thaliana ecotypes. Experimental results on primary and secondary metabolite profiling and genotypic variation were functionally integrated by a data mining strategy, which combines statistical output of metabolomics data with genome-derived biochemical pathway reconstruction and metabolic modeling. Correlations of biochemical model predictions and population-specific genetic variation indicated varying strategies of metabolic regulation on a population level which enabled the direct comparison, differentiation, and prediction of metabolic adaptation of the same species to different habitats. These differences were most pronounced at organic and amino acid metabolism as well as at the interface of primary and secondary metabolism and allowed for the direct classification of population-specific metabolic phenotypes within geographically contiguous sampling sites. KW - eco-metabolomics KW - in situ analysis KW - metabolomics KW - metabolic modeling KW - SNP KW - natural variation KW - Jacobian matrix KW - green systems biology Y1 - 2018 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-189560 SN - 1664-462X VL - 9 IS - 1556 ER - TY - JOUR A1 - Naseem, Muhammad A1 - Dandekar, Thomas T1 - The Role of Auxin-Cytokinin Antagonism in Plant-Pathogen Interactions JF - PLOS Pathogens N2 - No abstract available. KW - disease KW - pseudomas-syringae KW - arabidpsis thaliana KW - immunity KW - organogenesis KW - transcription KW - resistance KW - crosstalk Y1 - 2012 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-131901 VL - 8 IS - 11 ER -