Insufficient sensitivity of joint aspiration during the two-stage exchange of the hip with spacers

Please always quote using this URN: urn:nbn:de:bvb:20-opus-175576
  • Background: Evaluation of infection persistence during the two-stage exchange of the hip is challenging. Joint aspiration before reconstruction is supposed to rule out infection persistence. Sensitivity and specificity of synovial fluid culture and synovial leucocyte count for detecting infection persistence during the two-stage exchange of the hip were evaluated. Methods: Ninety-two aspirations before planned joint reconstruction during the two-stage exchange with spacers of the hip were retrospectively analyzed. Results: TheBackground: Evaluation of infection persistence during the two-stage exchange of the hip is challenging. Joint aspiration before reconstruction is supposed to rule out infection persistence. Sensitivity and specificity of synovial fluid culture and synovial leucocyte count for detecting infection persistence during the two-stage exchange of the hip were evaluated. Methods: Ninety-two aspirations before planned joint reconstruction during the two-stage exchange with spacers of the hip were retrospectively analyzed. Results: The sensitivity and specificity of synovial fluid culture was 4.6 and 94.3%. The sensitivity and specificity of synovial leucocyte count at a cut-off value of 2000 cells/μl was 25.0 and 96.9%. C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) values were significantly higher before prosthesis removal and reconstruction or spacer exchange (p = 0.00; p = 0.013 and p = 0.039; p = 0.002) in the infection persistence group. Receiver operating characteristic area under the curve values before prosthesis removal and reconstruction or spacer exchange for ESR were lower (0.516 and 0.635) than for CRP (0.720 and 0.671). Conclusions: Synovial fluid culture and leucocyte count cannot rule out infection persistence during the two-stage exchange of the hip.show moreshow less

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Metadaten
Author: Sebastian Philipp BoelchORCiD, Manuel Weissenberger, Frederik Spohn, Maximilian Rudert, Martin Luedemann
URN:urn:nbn:de:bvb:20-opus-175576
Document Type:Journal article
Faculties:Medizinische Fakultät / Lehrstuhl für Orthopädie
Language:English
Parent Title (English):Journal of Orthopedic Surgery and Research
Year of Completion:2018
Volume:13
Issue:7
Source:Journal of Orthopedic Surgery and Research (2018) 13:7. DOI: 10.1186/s13018-017-0703-z
DOI:https://doi.org/10.1186/s13018-017-0703-z
Dewey Decimal Classification:6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 617 Chirurgie und verwandte medizinische Fachrichtungen
Tag:hip; joint aspiration; periprosthetic infection; spacer; two-stage exchange
Release Date:2019/02/06
Licence (German):License LogoCC BY: Creative-Commons-Lizenz: Namensnennung 4.0 International