Incorporation and visualization of azido-functionalized N-oleoyl serinol in Jurkat cells, mouse brain astrocytes, 3T3 fibroblasts and human brain microvascular endothelial cells

Please always quote using this URN: urn:nbn:de:bvb:20-opus-191263
  • The synthesis and biological evaluation of azido-N-oleoyl serinol is reported. It mimicks biofunctional lipid ceramides and has shown to be capable of click reactions for cell membrane imaging in Jurkat and human brain microvascular endothelial cells.

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Author: T. Walter, L. Collenburg, L. Japtok, B. Kleuser, S. Schneider-Schaulies, N. Müller, J. Becam, A. Schubert-Unkmeir, J. N. Kong, E. Bieberich, J. Seibel
Document Type:Journal article
Faculties:Medizinische Fakultät / Institut für Hygiene und Mikrobiologie
Medizinische Fakultät / Institut für Virologie und Immunbiologie
Fakultät für Chemie und Pharmazie / Institut für Organische Chemie
Parent Title (English):Chemical Communications
Year of Completion:2016
Source:Chemical Communications (2016) 52:55, S. 8612-8614.
Dewey Decimal Classification:5 Naturwissenschaften und Mathematik / 54 Chemie / 547 Organische Chemie
6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit
Tag:Apoptosis; Ceramide; Golgi; Jurkat cells; N-oleoyl serinol
Release Date:2021/02/26
Licence (German):License LogoCC BY: Creative-Commons-Lizenz: Namensnennung