Chiral 2-alkylbranched acids, esters and alcohols. Preparation and stereospecific flavour evaluation
Please always quote using this URN: urn:nbn:de:bvb:20-opus-31898
- Racemic 2-alkylbranched acids are transformed to diastereomeric derivatives with (S)-2-hydroxy-3-phenylpropionic acid-N-methylamide or (S)-(-)-l-phenylethylamine and separated by liquid chromatography to pure diastereoisomers, which are subsequently hydrolyzed to yield optically pure acids. Enantiomeric alcohols are generated by LiAlH4-reduction of the corresponding acids, esters are synthesized by different methods. The odour impression of the enantiomeric compounds is investigated.
| Author: | Klaus Rettinger, Christian Burschka, Peter Scheeben, Heike Fuchs, Armin Mosandl |
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| URN: | urn:nbn:de:bvb:20-opus-31898 |
| Document Type: | Journal article |
| Faculties: | Fakultät für Chemie und Pharmazie / Institut für Anorganische Chemie |
| Language: | English |
| Year of Completion: | 1991 |
| Source: | In: Tetrahedron: Asymmetry (1991) 2, 10, S. 965 - 968. |
| Dewey Decimal Classification: | 5 Naturwissenschaften und Mathematik / 54 Chemie / 540 Chemie und zugeordnete Wissenschaften |
| GND Keyword: | Säure; Ester; Alkohol |
| Tag: | 2-alkylbranched acids; chirality and odour; esters and alcohols; flavour substances |
| Release Date: | 2010/12/13 |
| Licence (German): |  Deutsches Urheberrecht |