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Formin’ cellular structures: Physiological roles of Diaphanous (Dia) in actin dynamics
Please always quote using this URN: urn:nbn:de:bvb:20-opus-121305
- Members of the Diaphanous (Dia) protein family are key regulators of fundamental actin driven cellular processes, which are conserved from yeast to humans. Researchers have uncovered diverse physiological roles in cell morphology, cell motility, cell polarity, and cell division, which are involved in shaping cells into tissues and organs. The identification of numerous binding partners led to substantial progress in our understanding of the differential functions of Dia proteins. Genetic approaches and new microscopy techniques allow importantMembers of the Diaphanous (Dia) protein family are key regulators of fundamental actin driven cellular processes, which are conserved from yeast to humans. Researchers have uncovered diverse physiological roles in cell morphology, cell motility, cell polarity, and cell division, which are involved in shaping cells into tissues and organs. The identification of numerous binding partners led to substantial progress in our understanding of the differential functions of Dia proteins. Genetic approaches and new microscopy techniques allow important new insights into their localization, activity, and molecular principles of regulation.…
Author: | Sven Bogdan, Jörg Schultz, Jörg Grosshans |
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URN: | urn:nbn:de:bvb:20-opus-121305 |
Document Type: | Journal article |
Faculties: | Fakultät für Biologie / Theodor-Boveri-Institut für Biowissenschaften |
Language: | English |
Parent Title (English): | Communicative & Integrative Biology |
Year of Completion: | 2013 |
Volume: | 6 |
Issue: | e27634 |
Source: | Communicative & Integrative Biology 6:6, e27634; http://dx.doi.org/10.4161/cib.27634 |
DOI: | https://doi.org/10.4161/cib.27634 |
Pubmed Id: | https://pubmed.ncbi.nlm.nih.gov/24719676 |
Dewey Decimal Classification: | 5 Naturwissenschaften und Mathematik / 57 Biowissenschaften; Biologie / 570 Biowissenschaften; Biologie |
Tag: | Drosophila; actin; cytoskeleton; development; formin; nucleator |
Release Date: | 2016/02/18 |
Licence (German): | CC BY-NC: Creative-Commons-Lizenz: Namensnennung, Nicht kommerziell |