Diverse facets of sphingolipid involvement in bacterial infections
Zitieren Sie bitte immer diese URN: urn:nbn:de:bvb:20-opus-201757
- Sphingolipids are constituents of the cell membrane that perform various tasks as structural elements and signaling molecules, in addition to regulating many important cellular processes, such as apoptosis and autophagy. In recent years, it has become increasingly clear that sphingolipids and sphingolipid signaling play a vital role in infection processes. In many cases the attachment and uptake of pathogenic bacteria, as well as bacterial development and survival within the host cell depend on sphingolipids. In addition, sphingolipids canSphingolipids are constituents of the cell membrane that perform various tasks as structural elements and signaling molecules, in addition to regulating many important cellular processes, such as apoptosis and autophagy. In recent years, it has become increasingly clear that sphingolipids and sphingolipid signaling play a vital role in infection processes. In many cases the attachment and uptake of pathogenic bacteria, as well as bacterial development and survival within the host cell depend on sphingolipids. In addition, sphingolipids can serve as antimicrobials, inhibiting bacterial growth and formation of biofilms. This review will give an overview of our current information about these various aspects of sphingolipid involvement in bacterial infections.…
Autor(en): | Tobias C. Kunz, Vera Kozjak-Pavlovic |
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URN: | urn:nbn:de:bvb:20-opus-201757 |
Dokumentart: | Artikel / Aufsatz in einer Zeitschrift |
Institute der Universität: | Fakultät für Biologie / Theodor-Boveri-Institut für Biowissenschaften |
Sprache der Veröffentlichung: | Englisch |
Titel des übergeordneten Werkes / der Zeitschrift (Englisch): | Frontiers in Cell and Developmental Biology |
Erscheinungsjahr: | 2019 |
Band / Jahrgang: | 7 |
Heft / Ausgabe: | 203 |
Originalveröffentlichung / Quelle: | Frontiers in Cell and Developmental Biology 2019, 7:203. doi: 10.3389/fcell.2019.00203 |
DOI: | https://doi.org/10.3389/fcell.2019.00203 |
Allgemeine fachliche Zuordnung (DDC-Klassifikation): | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
Freie Schlagwort(e): | autophagy; ceramide; infection; pathogenic bacteria; sphingolipids |
Datum der Freischaltung: | 23.03.2020 |
Sammlungen: | Open-Access-Publikationsfonds / Förderzeitraum 2019 |
Lizenz (Deutsch): | CC BY: Creative-Commons-Lizenz: Namensnennung 4.0 International |