Pilot study of a new freely available computer-aided polyp detection system in clinical practice
Please always quote using this URN: urn:nbn:de:bvb:20-opus-324459
- Purpose Computer-aided polyp detection (CADe) systems for colonoscopy are already presented to increase adenoma detection rate (ADR) in randomized clinical trials. Those commercially available closed systems often do not allow for data collection and algorithm optimization, for example regarding the usage of different endoscopy processors. Here, we present the first clinical experiences of a, for research purposes publicly available, CADe system. Methods We developed an end-to-end data acquisition and polyp detection system named EndoMind.Purpose Computer-aided polyp detection (CADe) systems for colonoscopy are already presented to increase adenoma detection rate (ADR) in randomized clinical trials. Those commercially available closed systems often do not allow for data collection and algorithm optimization, for example regarding the usage of different endoscopy processors. Here, we present the first clinical experiences of a, for research purposes publicly available, CADe system. Methods We developed an end-to-end data acquisition and polyp detection system named EndoMind. Examiners of four centers utilizing four different endoscopy processors used EndoMind during their clinical routine. Detected polyps, ADR, time to first detection of a polyp (TFD), and system usability were evaluated (NCT05006092). Results During 41 colonoscopies, EndoMind detected 29 of 29 adenomas in 66 of 66 polyps resulting in an ADR of 41.5%. Median TFD was 130 ms (95%-CI, 80–200 ms) while maintaining a median false positive rate of 2.2% (95%-CI, 1.7–2.8%). The four participating centers rated the system using the System Usability Scale with a median of 96.3 (95%-CI, 70–100). Conclusion EndoMind’s ability to acquire data, detect polyps in real-time, and high usability score indicate substantial practical value for research and clinical practice. Still, clinical benefit, measured by ADR, has to be determined in a prospective randomized controlled trial.…
Author: | Thomas J. Lux, Michael Banck, Zita Saßmannshausen, Joel Troya, Adrian Krenzer, Daniel Fitting, Boban Sudarevic, Wolfram G. Zoller, Frank Puppe, Alexander Meining, Alexander Hann |
---|---|
URN: | urn:nbn:de:bvb:20-opus-324459 |
Document Type: | Journal article |
Faculties: | Fakultät für Mathematik und Informatik / Institut für Informatik |
Medizinische Fakultät / Medizinische Klinik und Poliklinik II | |
Language: | English |
Parent Title (English): | International Journal of Colorectal Disease |
Year of Completion: | 2022 |
Volume: | 37 |
Issue: | 6 |
Pagenumber: | 1349-1354 |
Source: | International Journal of Colorectal Disease (2022) 37:6, 1349-1354 DOI: 10.1007/s00384-022-04178-8 |
DOI: | https://doi.org/10.1007/s00384-022-04178-8 |
Dewey Decimal Classification: | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
Tag: | CADe; artificial intelligence; colonoscopy; deep learning; polyp |
Release Date: | 2024/02/28 |
Licence (German): | CC BY: Creative-Commons-Lizenz: Namensnennung 4.0 International |