Supraoptic nuclei in vasopressin and hemodynamic responses to hemorrhage in rats
Please always quote using this URN: urn:nbn:de:bvb:20-opus-63057
- CARDIOVASCULAR and vasopressin (A VP) responses to hcmorrhagc wcrc studicd in rats with lesions of the hypothalamic supraoptic nuclei (SONL). Bleeding caused hypotension and increase in heart rate (HR) and A VP. SONL rats failed to fully recover from bleeding as compared to normal rats. Plasma A VP in SONL rats was in the normal in basal conditions, but failed to increase to levels attained in normal rats throughout the post-hemorrhage period. These data suggcst that the supraoptic nuclei are the primary regulatory sitcs for A VP release inCARDIOVASCULAR and vasopressin (A VP) responses to hcmorrhagc wcrc studicd in rats with lesions of the hypothalamic supraoptic nuclei (SONL). Bleeding caused hypotension and increase in heart rate (HR) and A VP. SONL rats failed to fully recover from bleeding as compared to normal rats. Plasma A VP in SONL rats was in the normal in basal conditions, but failed to increase to levels attained in normal rats throughout the post-hemorrhage period. These data suggcst that the supraoptic nuclei are the primary regulatory sitcs for A VP release in rcsponse to hemorrhage and that lack of adequate A VP release significantly retards blood pressure recovery after bleeding.…
Author: | G. Feuerstein, R. L. Zerbe, Anna-Leena Sirén |
---|---|
URN: | urn:nbn:de:bvb:20-opus-63057 |
Document Type: | Journal article |
Faculties: | Medizinische Fakultät / Neurochirurgische Klinik und Poliklinik |
Language: | English |
Year of Completion: | 1991 |
Source: | In: Neuroreport (1991) 2, 612-614. |
Dewey Decimal Classification: | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
GND Keyword: | Neurobiologie |
Tag: | Hemorrhage; Hypothalamus; Supraoptic nucleus; Vasopressin |
Release Date: | 2012/07/30 |
Licence (German): | Deutsches Urheberrecht |