Genetically engineered S and F1C fimbriae differ in their contribution to adherence of Escherichia coli to cultured renal tubular cells
Please always quote using this URN: urn:nbn:de:bvb:20-opus-59644
- Escherichia coU K-12 strains producing S-fimbrial adhesins, FlC fimbriae, and mutagenized fimbriae were tested in a binding assay with a renal tubular cell line. S-fimbrial adhesins and FlC fimbriae mediated bindlog to tubular cells. The SfaA, SfaG, and SfaS subunits of S fimbriae contributed to attachment. Site-specific mutations in the sfaS gene reduced binding. The Inhibitionprofile of FlC fimbriae resembled that of S fimbriae.
| Author: | R. Marre, B. Kreft, Jörg Hacker |
|---|---|
| URN: | urn:nbn:de:bvb:20-opus-59644 |
| Document Type: | Journal article |
| Faculties: | Medizinische Fakultät / Institut für Molekulare Infektionsbiologie |
| Language: | English |
| Year of Completion: | 1990 |
| Source: | In: Infection and Immunity (1990) 58, 3434-3437. |
| Dewey Decimal Classification: | 5 Naturwissenschaften und Mathematik / 57 Biowissenschaften; Biologie / 570 Biowissenschaften; Biologie |
| GND Keyword: | Infektionsbiologie |
| Release Date: | 2011/11/26 |
| Licence (German): |  Deutsches Urheberrecht |