Isolation and Structural Elucidation of Novel Anti-Infective Naphthylisoquinoline Alkaloids from Ancistrocladus ealaensis, and Phytochemical Analysis of Two Congolese Medicinal Plants

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Herein described are the isolation, structural elucidation, and biological evaluation of highly thrilling monomeric and dimeric new naphthylisoquinoline alkaloids from A. ealaensis. The separation, chiral resolution, and characterization of a series of stereoisomeric 2,3-dihydrobenzofuran neolignans are also reported. The analytical and phytochemical analysis on two Congolese antimalarial herbal drugs is part of the last chapter of the results. In this last case, major concerns on widely used Congolese herbal drugs are discussed.
Im Rahmen dieser Dissertation werden Einblicke in die strukturelle Vielfalt und das therapeutische Potenzial von pflanzlichen Sekundärmetaboliten gewährt

Metadaten
Author:	Dieudonné Tshitenge Tshitenge
URN:	urn:nbn:de:bvb:20-opus-154175
Document Type:	Doctoral Thesis
Granting Institution:	Universität Würzburg, Graduate Schools
Faculties:	Graduate Schools / Graduate School of Life Sciences
Referee:	Prof. Dr. Gerhard Bringmann
Date of final exam:	2017/10/23
Language:	English
Year of Completion:	2019
DOI:	https://doi.org/10.25972/OPUS-15417
Dewey Decimal Classification:	5 Naturwissenschaften und Mathematik / 57 Biowissenschaften; Biologie / 570 Biowissenschaften; Biologie
GND Keyword:	Naphthylisochinolinalkaloide; Ancistrocladaceae; Kongo
Tag:	Alkaloid; Anti-infective; Isolation; Naphthylisoquinoline; Structural elucidation
Release Date:	2019/10/18
Licence (German):	CC BY: Creative-Commons-Lizenz: Namensnennung 4.0 International