Nerve biopsy in acquired neuropathies
Please always quote using this URN: urn:nbn:de:bvb:20-opus-259555
- A diagnosis of neuropathy can typically be determined through clinical assessment and focused investigation. With technological advances, including significant progress in genomics, the role of nerve biopsy has receded over recent years. However, making a specific and, in some cases, tissue-based diagnosis is essential across a wide array of potentially treatable acquired peripheral neuropathies. When laboratory investigations do not suggest a definitive diagnosis, nerve biopsy remains the final step to ascertain the etiology of the disease.A diagnosis of neuropathy can typically be determined through clinical assessment and focused investigation. With technological advances, including significant progress in genomics, the role of nerve biopsy has receded over recent years. However, making a specific and, in some cases, tissue-based diagnosis is essential across a wide array of potentially treatable acquired peripheral neuropathies. When laboratory investigations do not suggest a definitive diagnosis, nerve biopsy remains the final step to ascertain the etiology of the disease. The present review highlights the utility of nerve biopsy in confirming a diagnosis, while further illustrating the importance of a tissue-based diagnosis in relation to treatment strategies, particularly when linked to long-term immunosuppressive therapies,…
Author: | Claudia SommerORCiD, Antonia S. Carroll, Haruki Koike, Masahisa Katsuno, Nora Ort, Gen Sobue, Steve Vucic, Judith M. Spies, Kathrin Doppler, Matthew C. Kiernan |
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URN: | urn:nbn:de:bvb:20-opus-259555 |
Document Type: | Journal article |
Faculties: | Medizinische Fakultät / Neurologische Klinik und Poliklinik |
Language: | English |
Parent Title (English): | Journal of the Peripheral Nervous System |
Year of Completion: | 2021 |
Volume: | 26 |
Issue: | S2 |
Pagenumber: | S21-S41 |
Source: | Journal of the Peripheral Nervous System 2021, 26(S2):S21-S41. DOI: 10.1111/jns.12464 |
DOI: | https://doi.org/10.1111/jns.12464 |
Dewey Decimal Classification: | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
Tag: | inflammatory neuropathy; nerve biopsy; nerve tumor; neuroleukemiosis |
Release Date: | 2022/03/28 |
Licence (German): | CC BY-NC-ND: Creative-Commons-Lizenz: Namensnennung, Nicht kommerziell, Keine Bearbeitungen 4.0 International |