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Panniculitis-like T-cell-lymphoma in the mesentery associated with hemophagocytic syndrome: autopsy case report
Please always quote using this URN: urn:nbn:de:bvb:20-opus-322665
- Background Panniculitis-like T-cell lymphoma is an uncommon type of non-Hodgkin lymphoma, occurring usually in the form of nodules within the subcutaneous fat tissue of the extremities or trunk. In the literature, subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is described as a distinct type of T-cell lymphoma with a variable clinical behavior, depending on molecular phenotype of T-cell receptor (TCR) and on the presence or absence of hemophagocytic syndrome. Case presentation We present a bioptic and autoptic case of a 65-yearsBackground Panniculitis-like T-cell lymphoma is an uncommon type of non-Hodgkin lymphoma, occurring usually in the form of nodules within the subcutaneous fat tissue of the extremities or trunk. In the literature, subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is described as a distinct type of T-cell lymphoma with a variable clinical behavior, depending on molecular phenotype of T-cell receptor (TCR) and on the presence or absence of hemophagocytic syndrome. Case presentation We present a bioptic and autoptic case of a 65-years old Caucasian man with panniculitic T-cell lymphoma with morphological and immunohistochemical features of SPTCL, limited to the retroperitoneal and mesenteric mass, i.e. without any cutaneous involvement, and associated with severe hemophagocytic lymphohistiocytosis. Conclusion A panniculitic T-cell lymphoma with morphological and molecular features of SPTCL, which is limited to mesentery, i.e. does not involve subcutaneous fat, seems to be exceedingly rare.…
Author: | Jan Hrudka, Václav Eis, Josef Heřman, Zuzana Prouzová, Andreas Rosenwald, Duška František |
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URN: | urn:nbn:de:bvb:20-opus-322665 |
Document Type: | Journal article |
Faculties: | Medizinische Fakultät / Pathologisches Institut |
Language: | English |
Parent Title (English): | Diagnostic Pathology |
Year of Completion: | 2019 |
Volume: | 14 |
Article Number: | 80 |
Source: | Diagnostic Pathology (2019) 14:80. https://doi.org/10.1186/s13000-019-0854-9 |
DOI: | https://doi.org/10.1186/s13000-019-0854-9 |
Dewey Decimal Classification: | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
Tag: | T-cell lymphoma; hemophagocytosis; lymphohistiocytosis; mesentery; panniculitis |
Release Date: | 2024/03/05 |
Licence (German): | CC BY: Creative-Commons-Lizenz: Namensnennung 4.0 International |