Crystal structure of the antibiotic monensin similarities and differences betweeen free acid and metal complex
Please always quote using this URN: urn:nbn:de:bvb:20-opus-61228
- The structure of monensin, C36H620 11 , has been deterrnined by X-ray analysis of its crystalline monohydrate (orthorhombic, a = 15.15, b = 23.61, c = 10.65 A, Z = 4, space group P212121). Phases were assigned by direct methods, malring use of the 'tangent formula'. Although the conformation of the free acid resembles that of the silver salt in being cyclic, there are differences in the hydrogen bonding pattern. These featurcs are discussed in relation to the cornplexation of metal ions by m.onensin.
| Author: | Werner K. Lutz, F. K. Winkler, J. D. Dunitz |
|---|---|
| URN: | urn:nbn:de:bvb:20-opus-61228 |
| Document Type: | Journal article |
| Faculties: | Medizinische Fakultät / Institut für Pharmakologie und Toxikologie |
| Language: | English |
| Year of Completion: | 1971 |
| Source: | In: Helvetica chimica acta (1971) 54, 4, 1103-8. |
| Dewey Decimal Classification: | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
| GND Keyword: | Toxikologie |
| Release Date: | 2012/01/31 |
| Licence (German): |  Deutsches Urheberrecht |