Crosslinking of hydrophilic polymers using polyperoxides
Please always quote using this URN: urn:nbn:de:bvb:20-opus-238109
- Hydrogels that can mimic mechanical properties and functions of biological tissue have attracted great interest in tissue engineering and biofabrication. In these fields, new materials and approaches to prepare hydrogels without using toxic starting materials or materials that decompose into toxic compounds remain to be sought after. Here, we report the crosslinking of commercial, unfunctionalized hydrophilic poly(2-ethyl-2-oxazoline) using peroxide copolymers in their melt. The influence of temperature, peroxide copolymer concentration, andHydrogels that can mimic mechanical properties and functions of biological tissue have attracted great interest in tissue engineering and biofabrication. In these fields, new materials and approaches to prepare hydrogels without using toxic starting materials or materials that decompose into toxic compounds remain to be sought after. Here, we report the crosslinking of commercial, unfunctionalized hydrophilic poly(2-ethyl-2-oxazoline) using peroxide copolymers in their melt. The influence of temperature, peroxide copolymer concentration, and duration of the crosslinking process has been investigated. The method allows to create hydrogels from unfunctionalized polymers in their melt and to control the mechanical properties of the resulting materials. The design of hydrogels with a suitable mechanical performance is of crucial importance in many existing and potential applications of soft materials, including medical applications.…
Author: | Solomiia Borova, Victor Tokarev, Philipp Stahlhut, Robert Luxenhofer |
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URN: | urn:nbn:de:bvb:20-opus-238109 |
Document Type: | Journal article |
Faculties: | Fakultät für Chemie und Pharmazie / Institut für Funktionsmaterialien und Biofabrikation |
Language: | English |
Parent Title (English): | Colloid and Polymer Science |
Year of Completion: | 2020 |
Volume: | 298 |
Pagenumber: | 1699–1713 |
Source: | Colloid and Polymer Science (2020) 298:1699–1713. https://doi.org/10.1007/s00396-020-04738-w |
DOI: | https://doi.org/10.1007/s00396-020-04738-w |
Dewey Decimal Classification: | 5 Naturwissenschaften und Mathematik / 54 Chemie / 540 Chemie und zugeordnete Wissenschaften |
Tag: | hydrogels; peroxide containing copolymers; poly(2-ethyl-2-oxazoline); radical crosslinking; thermal crosslinking |
Release Date: | 2021/05/20 |
Licence (German): | CC BY: Creative-Commons-Lizenz: Namensnennung 4.0 International |