Toxic trace elements in maternal and cord blood and social determinants in a Bolivian mining city
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- This study assessed lead, arsenic, and antimony in maternal and cord blood, and associations between maternal concentrations and social determinants in the Bolivian mining city of Oruro using the baseline assessment of the ToxBol/Mine-Niño birth cohort. We recruited 467 pregnant women, collecting venous blood and sociodemographic information as well as placental cord blood at birth. Metallic/semimetallic trace elements were measured using inductively coupled plasma mass spectrometry. Lead medians in maternal and cord blood were significantlyThis study assessed lead, arsenic, and antimony in maternal and cord blood, and associations between maternal concentrations and social determinants in the Bolivian mining city of Oruro using the baseline assessment of the ToxBol/Mine-Niño birth cohort. We recruited 467 pregnant women, collecting venous blood and sociodemographic information as well as placental cord blood at birth. Metallic/semimetallic trace elements were measured using inductively coupled plasma mass spectrometry. Lead medians in maternal and cord blood were significantly correlated (Spearman coefficient = 0.59; p < 0.001; 19.35 and 13.50 μg/L, respectively). Arsenic concentrations were above detection limit (3.30 μg/L) in 17.9 % of maternal and 34.6 % of cord blood samples. They were not associated (Fischer’s p = 0.72). Antimony medians in maternal and cord blood were weakly correlated (Spearman coefficient = 0.15; p < 0.03; 9.00 and 8.62 μg/L, respectively). Higher concentrations of toxic elements in maternal blood were associated with maternal smoking, low educational level, and partner involved in mining.…
Autor(en): | Flavia L. Barbieri, Jacques Gardon, María Ruiz-Castell, Pamela Paco V., Rebecca Muckelbauer, Corinne Casiot, Rémi Freydier, Jean-Louis Duprey, Chih-Mei Chen, Jacqueline Müller-Nordhorn, Thomas Keil |
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URN: | urn:nbn:de:bvb:20-opus-150385 |
Dokumentart: | Artikel / Aufsatz in einer Zeitschrift |
Institute der Universität: | Medizinische Fakultät / Institut für Klinische Epidemiologie und Biometrie |
Sprache der Veröffentlichung: | Englisch |
Titel des übergeordneten Werkes / der Zeitschrift (Englisch): | International Journal of Environmental Health Research |
Erscheinungsjahr: | 2016 |
Band / Jahrgang: | 26 |
Heft / Ausgabe: | 2 |
Seitenangabe: | 158-174 |
Originalveröffentlichung / Quelle: | International Journal of Environmental Health Research, 2016 Vol. 26, No. 2, 158–174. DOI: 10.1080/09603123.2015.1061114 |
DOI: | https://doi.org/10.1080/09603123.2015.1061114 |
PubMed-ID: | https://pubmed.ncbi.nlm.nih.gov/PMC4733940 |
Allgemeine fachliche Zuordnung (DDC-Klassifikation): | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
Freie Schlagwort(e): | environmental exposure; maternal exposure; metallic trace elements; prenatal exposure; risk factors |
Datum der Freischaltung: | 24.01.2019 |
Lizenz (Deutsch): | CC BY-NC-ND: Creative-Commons-Lizenz: Namensnennung, Nicht kommerziell, Keine Bearbeitungen 4.0 International |