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Environmental and hereditary factors in the causation of neoplasia, based on studies of the Xiphophorus fish melanoma system

Please always quote using this URN: urn:nbn:de:bvb:20-opus-86402
  • Neoplasia in Xiphophorus can be classified into: a) a Jarge group triggered by carcinogens; b) a large group triggered by promoters; and c) a small group that develops "spontaneously" according to Mendelian Jaw. The process leading to susceptibility for neoplasia is represented by the disintegration of gene systems that normally protect the fish from neoplasia. Interpopulational arid interracial hybridization is the most effective process that Ieads to disintegration of the protective gene systems. Environmental factors may completeNeoplasia in Xiphophorus can be classified into: a) a Jarge group triggered by carcinogens; b) a large group triggered by promoters; and c) a small group that develops "spontaneously" according to Mendelian Jaw. The process leading to susceptibility for neoplasia is represented by the disintegration of gene systems that normally protect the fish from neoplasia. Interpopulational arid interracial hybridization is the most effective process that Ieads to disintegration of the protective gene systems. Environmental factors may complete disintegration in somatic cells and thus may trigger neoplasia. The applications of the findings on Xiphophorus to humans are discussed.show moreshow less

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Metadaten
Author: F. Anders, E. Scholl, Manfred Schartl
URN:urn:nbn:de:bvb:20-opus-86402
Document Type:Conference Proceeding
Faculties:Medizinische Fakultät / Theodor-Boveri-Institut für Biowissenschaften
Language:English
Year of Completion:1981
Source:In: Phenotypic Expression in Pigment Cells: Pigment Cell / ed. Makoto Seiji. - [Tokyo]: Univ. of Tokyo Press, 1981. - S. 491-499. - ISBN: 0-86008-293-8
Dewey Decimal Classification:5 Naturwissenschaften und Mathematik / 54 Chemie / 540 Chemie und zugeordnete Wissenschaften
GND Keyword:Schwertkärpfling; Gen; Umweltfaktor; Tumor
Release Date:2014/06/12
Licence (German):License LogoDeutsches Urheberrecht