IgG monoclonal antibodies that inhibit osteoinductivity of human bone matrix-derived proteins (hBMP/NCP)
Please always quote using this URN: urn:nbn:de:bvb:20-opus-62388
- Monoclonal hBMP/NCP (human bone morphogenetic protein anrl associaterl noncollagenous proteins) antiborlies of the lgG class were prorlucerl. In vitro, 12 of 19 hBMP/NCP antiborlies showerl functional inhibition of hBMP/ NCP-induced chondroneogenesis in a neonatal muscle tissue assay. Inducing factors were characterized by their inhibiting antibodies with immunoblotting. Several peptide factors seem to be involved in the cascade of inducerl chondro- and osteogenesis.
| Author: | N. Kübler, J. Reuther, T. Kirchner, M. Pfaff, H. K. Müller-Hermelink, R. Albert, Walter Sebald |
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| URN: | urn:nbn:de:bvb:20-opus-62388 |
| Document Type: | Journal article |
| Faculties: | Fakultät für Biologie / Theodor-Boveri-Institut für Biowissenschaften |
| Language: | English |
| Year of Completion: | 1994 |
| Source: | In: International journal of oral and maxillofacial surgery (1994 Dec) 23, 6 part 2, 420-422. |
| Dewey Decimal Classification: | 5 Naturwissenschaften und Mathematik / 57 Biowissenschaften; Biologie / 570 Biowissenschaften; Biologie |
| GND Keyword: | Biochemie |
| Tag: | bone morphogenetic proteins; cartilage induction; neutralizing antibodies |
| Release Date: | 2012/03/16 |
| Licence (German): |  Deutsches Urheberrecht |