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Evaluation of environmental and hereditary factors in carcinogenesis, based on studies in Xiphophorus

Please always quote using this URN: urn:nbn:de:bvb:20-opus-72741
  • Neoplasia in Xiphophorus can be classified into a) a large group that is triggered by carcinogens; b) a large group triggered by promoters; c) a small group that develops "spontaneously" following interpopulational and interracial hybridizations; and d) a small group that develops "spontaneously" following germ line mutation. The process leading to susceptibility for neoplasia is represented by the disintegration of gene systems that normally protect the fish from neoplasia. Hybridization is the most effective process that leads toNeoplasia in Xiphophorus can be classified into a) a large group that is triggered by carcinogens; b) a large group triggered by promoters; c) a small group that develops "spontaneously" following interpopulational and interracial hybridizations; and d) a small group that develops "spontaneously" following germ line mutation. The process leading to susceptibility for neoplasia is represented by the disintegration of gene systems that normally protect the fish from neoplasia. Hybridization is the most effective process that leads to disintegration of the protection gene systems. Environmental factors may complete disintegration and thus may trigger neoplasia. It is discussed whether the findings on Xiphophorus may also apply to humans.show moreshow less

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Metadaten
Author: F. Anders, Manfred Schartl, E. Scholl
URN:urn:nbn:de:bvb:20-opus-72741
Document Type:Conference Proceeding
Faculties:Medizinische Fakultät / Theodor-Boveri-Institut für Biowissenschaften
Language:English
Year of Completion:1981
Source:In: Phyletic Approaches to Cancer / ed. by. Clyde J. Dawe. - Tokyo: Japan Scientific Soc. Press, 1981. - S. 289-309. - (Proceedings of the international symposium of the Princess Takamatsu Cancer Research Fund ; 11)
Dewey Decimal Classification:5 Naturwissenschaften und Mathematik / 54 Chemie / 540 Chemie und zugeordnete Wissenschaften
GND Keyword:Schwertkärpfling; Gen; Umweltfaktor; Carcinogenese
Release Date:2014/05/22
Licence (German):License LogoDeutsches Urheberrecht