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Formin’ cellular structures: Physiological roles of Diaphanous (Dia) in actin dynamics

Please always quote using this URN: urn:nbn:de:bvb:20-opus-121305
  • Members of the Diaphanous (Dia) protein family are key regulators of fundamental actin driven cellular processes, which are conserved from yeast to humans. Researchers have uncovered diverse physiological roles in cell morphology, cell motility, cell polarity, and cell division, which are involved in shaping cells into tissues and organs. The identification of numerous binding partners led to substantial progress in our understanding of the differential functions of Dia proteins. Genetic approaches and new microscopy techniques allow importantMembers of the Diaphanous (Dia) protein family are key regulators of fundamental actin driven cellular processes, which are conserved from yeast to humans. Researchers have uncovered diverse physiological roles in cell morphology, cell motility, cell polarity, and cell division, which are involved in shaping cells into tissues and organs. The identification of numerous binding partners led to substantial progress in our understanding of the differential functions of Dia proteins. Genetic approaches and new microscopy techniques allow important new insights into their localization, activity, and molecular principles of regulation.show moreshow less

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Metadaten
Author: Sven Bogdan, Jörg Schultz, Jörg Grosshans
URN:urn:nbn:de:bvb:20-opus-121305
Document Type:Journal article
Faculties:Fakultät für Biologie / Theodor-Boveri-Institut für Biowissenschaften
Language:English
Parent Title (English):Communicative & Integrative Biology
Year of Completion:2013
Volume:6
Issue:e27634
Source:Communicative & Integrative Biology 6:6, e27634; http://dx.doi.org/10.4161/cib.27634
DOI:https://doi.org/10.4161/cib.27634
Pubmed Id:https://pubmed.ncbi.nlm.nih.gov/24719676
Dewey Decimal Classification:5 Naturwissenschaften und Mathematik / 57 Biowissenschaften; Biologie / 570 Biowissenschaften; Biologie
Tag:Drosophila; actin; cytoskeleton; development; formin; nucleator
Release Date:2016/02/18
Licence (German):License LogoCC BY-NC: Creative-Commons-Lizenz: Namensnennung, Nicht kommerziell