The human osteosarcoma cell line U-2 OS expresses a 3.8 kilobase mRNA which codes for the sequence of the PDGF-B chain
Please always quote using this URN: urn:nbn:de:bvb:20-opus-62588
- A cDNA clone of about 2500 basepairswas prepared from the human osteosarcoma cellline U-2 OS by hybridizing with a v-sis probe. Sequence analysis showed that this cDNA contains the coding region for the PDGF-B chain. Here we report that the mitogen secreted by these osteosarcoma cells contains the PDGF-B chain and is probably a homodimer of two B-chains.
| Author: | H. A. Weich, Walter Sebald, H. U. Schairer, J. Hoppe |
|---|---|
| URN: | urn:nbn:de:bvb:20-opus-62588 |
| Document Type: | Journal article |
| Faculties: | Fakultät für Biologie / Theodor-Boveri-Institut für Biowissenschaften |
| Language: | English |
| Year of Completion: | 1986 |
| Source: | In: FEBS Letters (1986 Mar 31) , 198(2), 344-348. |
| Dewey Decimal Classification: | 5 Naturwissenschaften und Mathematik / 57 Biowissenschaften; Biologie / 570 Biowissenschaften; Biologie |
| GND Keyword: | Biochemie |
| Tag: | Oncogene; Platelet-derived growthfactor; Tumor cell; cDNA |
| Release Date: | 2012/04/25 |
| Licence (German): |  Deutsches Urheberrecht |